Works Published in 2017
Displaying works 1 - 20 of 289 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2017 journal article
Lipopolysaccharide-induced neutrophil extracellular trap formation in canine neutrophils is dependent on histone H3 citrullination by peptidylarginine deiminase
Veterinary Immunology and Immunopathology, 193-194, 29–37.
escholarship.org (repository)
Sources: Crossref, NC State University Libraries, ORCID
Added: December 10, 2023
2017 journal article
Evaluation of the analgesic and pharmacokinetic properties of transdermally administered fentanyl in goats.
Journal of Veterinary Emergency and Critical Care (San Antonio, Tex. : 2001).
MeSH headings : Administration, Cutaneous; Analgesics, Opioid / administration & dosage; Analgesics, Opioid / pharmacokinetics; Analgesics, Opioid / pharmacology; Animals; Female; Fentanyl / administration & dosage; Fentanyl / pharmacokinetics; Fentanyl / pharmacology; Goat Diseases / drug therapy; Goats; Pain, Postoperative / drug therapy; Pain, Postoperative / veterinary; Prospective Studies
TL;DR:
Ease of administration, duration of analgesia, and decreased dosing frequency make TFPs an attractive option for pain management in goats and resulted in consistent FEN absorption and plasma concentrations within the human and ovine therapeutic ranges.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: March 16, 2023
2017 journal article
Association between Survival Time and Changes in NT-proBNP in Cats Treated for Congestive Heart Failure
Journal of Veterinary Internal Medicine, 31(3), 678–684.
MeSH headings : Animals; Biomarkers / blood; Cat Diseases / blood; Cat Diseases / mortality; Cats; Female; Heart Failure / mortality; Heart Failure / veterinary; Male; Natriuretic Peptide, Brain / blood; Peptide Fragments / blood; Prospective Studies; Severity of Illness Index; Survival Analysis
TL;DR:
Cats with a larger percent decrease in NT‐proBNP during hospitalization and no evidence of CHF at the time of re‐evaluation had longer survival times, and additional studies are needed to determine whether NT‐ ProBNP can help guide treatment in cats with CHF.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: February 23, 2023
2017 journal article
Protein corona modulation of hepatocyte uptake and molecular mechanisms of gold nanoparticle toxicity
Nanotoxicology, 11(1), 64–75.
Contributors: K. Choi*, J. Riviere * & N. Monteiro-Riviere*
author keywords: Gold nanoparticles; human hepatocytes; cell uptake; cytochrome P450; mechanisms of action
MeSH headings : Albumins / chemistry; Blood Proteins / chemistry; Cell Survival / drug effects; Dose-Response Relationship, Drug; Gene Expression Profiling; Gold / chemistry; Gold / metabolism; Gold / toxicity; Hepatocytes / drug effects; Hepatocytes / metabolism; Humans; Metal Nanoparticles / chemistry; Metal Nanoparticles / toxicity; Polyethylene Glycols / chemistry; Polyethyleneimine / chemistry; Protein Corona / metabolism; Reactive Oxygen Species / metabolism; Transcriptome / drug effects
TL;DR:
Human hepatic uptake of 40 and 80 nm AuNP with branched polyethylenimine (BPEI), lipoic acid (LA) and polyethylene glycol (PEG) coatings as well as human plasma protein (HP) and human serum albumin (HSA) coronas was investigated to better understanding of the dramatic effect of protein coronas (PC) on AuNP cellular uptake, cytotoxicity and their underlying molecular mechanisms of action.
(via Semantic Scholar)
Source: ORCID
Added: September 25, 2022
2017 chapter
Multi-walled carbon nanotube exposure alters protein expression in human keratinocytes
In Nanomedicine in Cancer (pp. 461–485).
Contributors: F. Witzmann & N. Monteiro-Riviere
Source: ORCID
Added: September 25, 2022
2017 journal article
Intracellular imaging of quantum dots, gold, and iron oxide nanoparticles with associated endocytic pathways
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 9(2).
Contributors: D. Chen *, N. Monteiro-Riviere* & L. Zhang *
MeSH headings : Animals; Cell Line; Cell Membrane / chemistry; Cell Membrane / metabolism; Endocytosis / physiology; Gold; Humans; Intracellular Space / chemistry; Intracellular Space / diagnostic imaging; Intracellular Space / metabolism; Membrane Microdomains; Metal Nanoparticles; Mice; Molecular Imaging / methods; Nanomedicine; Quantum Dots
TL;DR:
Knowing the different methodologies used to determine the endocytic pathways will increase the understanding of NP toxicity, cancer cell targeting, and imaging, so that surface coatings can be created for efficient cell uptake of metallic NP with minimal cytotoxicity.
(via Semantic Scholar)
Source: ORCID
Added: September 25, 2022
2017 chapter
Abstract TMEM-020: OVARIAN ADENOCARCINOMA IN JAGUARS ( PANTHERA ONCA ): A NATURALLY-OCCURRING MODEL OF HUMAN INHERITED OVARIAN CANCER?
Contributors: S. Corner, M. Parys, A. Moresco* , V. Yuzbasiyan-Gurkan & D. Agnew *
TL;DR:
The purpose of this study is to investigate the genetic pathogenesis of ovarian adenocarcinoma in jaguars by identifying an inherited germline mutation in BRCA1, BRC a2 or other cancer genes with known involvement in human ovarian and breast cancer.
(via Semantic Scholar)
Source: ORCID
Added: June 16, 2022
2017 journal article
59 EFFECT OF PELLET VOLUME AND THAWING TEMPERATURE ON VITRIFICATION EFFICACY WITH DOMESTIC CAT SEMEN COLLECTED VIA URETHRAL CATHETERIZATION
Reproduction Fertility and Development.
Contributors: A. Moresco* , H. Bateman*, J. Newsom* & W. Swanson*
TL;DR:
Although variations in pellet volume and thawing temperature had minimal effect on sperm motility or acrosome status immediately post-thaw, sperm function appeared to be enhanced when vitrified pellets were thawed at a higher temperature.
(via Semantic Scholar)
Source: ORCID
Added: June 16, 2022
2017 journal article
Presumptive keratoglobus in a great horned owl (Bubo virginianus)
Veterinary Ophthalmology, 20(6), 560–567.
Contributors: R. Lau, A. Moresco* , S. Woods*, C. Reilly*, M. Hawkins*, C. Murphy *, S. Hollingsworth*, D. Hacker, K. Freeman*
author keywords: avian; great horned owl; keratoconus; keratoglobus; megalocornea; raptor
MeSH headings : Animals; Animals, Wild; Bird Diseases / diagnosis; Bird Diseases / pathology; Corneal Diseases / diagnosis; Corneal Diseases / pathology; Corneal Diseases / veterinary; Male; Strigiformes
TL;DR:
This GHOW represents the first reported case of presumptive keratoglobus in a raptor, and was humanely euthanized.
(via Semantic Scholar)
Source: ORCID
Added: June 16, 2022
2017 conference paper
Ovarian adenocarcinoma in jaguars (Panthera onca): a naturally-occurring model of human inherited ovarian cancer?
11th Biennial Ovarian Cancer Research Symposium, –020. http://clincancerres.aacrjournals.org/content/23/11_Supplement/TMEM-020
Source: ORCID
Added: June 16, 2022
2017 journal article
SERIAL ULTRASOUND to ESTIMATE FETAL GROWTH CURVES in SOUTHERN TAMANDUA (TAMANDUA TETRADACTYLA)
Journal of Zoo and Wildlife Medicine, 48(2), 294–297.
Contributors: R. Thompson *, T. Wolf, H. Robertson, M. Colburn, A. Moreno *, A. Moresco* , A. Napier, S. Nofs *
author keywords: Anteater; fetal growth; reproduction; Tamandua tetradactyla; ultrasound; Xenarthra
MeSH headings : Animals; Female; Pregnancy; Pregnancy, Animal / physiology; Species Specificity; Ultrasonography / veterinary; Xenarthra / physiology
TL;DR:
From 2012 to 2015, 16 pregnancies were monitored by ultrasonography in nine tamanduas (Tamandua tetradactyla) housed in three zoological facilities, establishing fetal growth curves using thoracic and skull landmarks described for giant anteaters.
(via Semantic Scholar)
Source: ORCID
Added: June 16, 2022
2017 journal article
Epidemiology of bacterial conjunctivitis in chinchillas (Chinchilla lanigera): 49 cases (2005 to 2015)
Journal of Small Animal Practice, 58(4), 238–245.
MeSH headings : Animals; Bacteria / classification; Bacteria / isolation & purification; Chinchilla; Conjunctivitis, Bacterial / epidemiology; Conjunctivitis, Bacterial / microbiology; Conjunctivitis, Bacterial / veterinary; Disease Susceptibility / veterinary; Female; Male; Retrospective Studies; Treatment Outcome
TL;DR:
With the exception of duration of clinical signs, information on the anamnesis or physical examination findings cannot aid in distinguishing conjunctivitis caused by P. aeruginosa or other Gram-negative bacteria from the ones caused by Gram-positive bacteria.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 2, 2022
2017 journal article
Comparison of rectal and tympanic thermometry in chinchillas (Chinchilla lanigera)
Journal of American Veterinary Medical Association, 251(5), 552–558.
MeSH headings : Animals; Body Temperature / physiology; Chinchilla; Ear; Fever; Prospective Studies; Rectum; Reproducibility of Results; Thermometers
TL;DR:
Rectal thermometer insertion depth and duration of manual restraint had a significant effect on rectal temperature measurements in chinchillas.
(via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries
Added: June 2, 2022
2017 journal article
Modeling the transmission of Perkinsus marinus in the Eastern oyster Crassostrea virginica
Fisheries Research, 186, 82–93.
Source: ORCID
Added: November 8, 2021
2017 journal article
Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression
Proceedings of the National Academy of Sciences of the United States of America, 114(30), E6147–E6156.
author keywords: siRNA; lipopolymeric nanoparticle; glioblastoma transcription factor; brain tumor-initiating cells; convection-enhanced delivery
MeSH headings : Animals; Carcinogenesis / genetics; Drug Resistance, Neoplasm; Female; Genetic Therapy / methods; Glioblastoma / drug therapy; Glioblastoma / genetics; Glioblastoma / pathology; Humans; Male; Mice; Mice, Nude; Nanoparticles / therapeutic use; RNA Interference; Xenograft Model Antitumor Assays
TL;DR:
A lipopolymeric nanoparticle (LPNP) formulation is reported that demonstrates a surprisingly high affinity for BTICs and the capacity to encapsulate multiple siRNAs for potent and targeted anti-BTIC therapy and establishes a flexible nonviral gene therapy platform with thecapacity to channel multiplexed RNAi schemes to address the challenges posed by tumor heterogeneity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: October 31, 2021
2017 journal article
Hitting the nail on the head: Combining oncolytic adenovirusmediated virotherapy and immunomodulation for the treatment of glioma
Oncotarget, 8(51), 89391–89405.
Contributors: W. Panek* , J. Kane*, J. Young *, A. Rashidi*, J. Kim*, D. Kanojia *, M. Lesniak *
author keywords: combinatory therapy; glioma; immunomodulator(s); checkpoint blockade; oncolytic adenovirus
TL;DR:
The strengths and weaknesses of adenoviral oncolytic therapy are discussed, and the genetic modifications that result in more effective and targeted viral agents are highlighted and areas for which more work is needed are considered.
(via Semantic Scholar)
Source: ORCID
Added: October 31, 2021
2017 journal article
Multiplexed nanomedicine for brain tumors: Nanosized Hercules to tame our Lernaean Hydra inside?
Nanomedicine, 12(20), 2435–2439.
Contributors: W. Panek* , O. Khan *, D. Yu * & M. Lesniak *
author keywords: GBM; nanoparticle; nanomedicine; brain tumor; siRNA; convection enhanced delivery; BTIC/brain tumor-initiating cells; stem cell transcription factor
Source: ORCID
Added: October 31, 2021
2017 journal article
A Comparative Study of Replication-Incompetent and -Competent Adenoviral Therapy-Mediated Immune Response in a Murine Glioma Model
Molecular Therapy - Oncolytics, 5, 97–104.
Contributors: J. Kim*, J. Miska *, J. Young *, A. Rashidi*, J. Kane*, W. Panek* , D. Kanojia *, Y. Han *, I. Balyasnikova *, M. Lesniak *
TL;DR:
It is suggested that cell death caused by replication-competent adenoviral vectors is required to induce a significant anti-tumor immune response and survival benefits in immunocompetent mice bearing intracranial glioma.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: October 31, 2021
2017 journal article
Surface chemistry of gold nanoparticles determines the biocorona composition impacting cellular uptake, toxicity and gene expression profiles in human endothelial cells
Nanotoxicology, 11(4), 507–519.
Contributors: P. Chandran *, J. Riviere * & N. Monteiro-Riviere*
author keywords: Biocorona; gold nanoparticles; surface chemistry; endothelial cells; mechanistic toxicology
MeSH headings : Albumins / metabolism; Cell Survival / drug effects; Circular Dichroism; Endothelial Cells / drug effects; Endothelial Cells / metabolism; Gold / chemistry; Gold / toxicity; Human Umbilical Vein Endothelial Cells; Humans; Metal Nanoparticles / chemistry; Metal Nanoparticles / toxicity; Particle Size; Polyethylene Glycols / chemistry; Polyethyleneimine / chemistry; Protein Corona / metabolism; Proteomics; Surface Properties; Transcriptome / drug effects
TL;DR:
NP surface chemistry is shown to play the dominant role over size in determining the biocorona composition, which in turn modulates cell uptake, and biological responses, consequently defining the potential safety and efficacy of nanoformulations.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: April 29, 2021
2017 journal article
Bacterial endotoxin (lipopolysaccharide) binds to the surface of gold nanoparticles, interferes with biocorona formation and induces human monocyte inflammatory activation
Nanotoxicology, 11(9-10), 1157–1175.
Contributors: Y. Li *, Z. Shi *, I. Radauer-Preiml*, A. Andosch*, E. Casals *, U. Luetz-Meindl*, M. Cobaleda*, Z. Lin *
author keywords: Nano-immunosafety; endotoxin contamination; biocorona modulation; gold nanoparticles; inflammatory effects
MeSH headings : Adsorption; Blood Proteins / chemistry; Computational Biology; Gold / chemistry; Gold / toxicity; HEK293 Cells; Humans; Inflammation; Interleukin-1 / biosynthesis; Lipopolysaccharides / chemistry; Lipopolysaccharides / toxicity; Metal Nanoparticles / chemistry; Metal Nanoparticles / toxicity; Models, Biological; Monocytes / drug effects; Monocytes / immunology; Particle Size; Protein Corona / analysis; Surface Properties
TL;DR:
The unintentional adsorption of LPS onto the NP surface can affect the biocorona formation and the inflammatory properties of NPs.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: April 29, 2021
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