Scott Campbell Coleman

Works (3)

Updated: February 10th, 2025 14:29

2000 article

Comparative Metabolism of Chloroacetamide Herbicides and Selected Metabolites in Human and Rat Liver Microsomes

Coleman, S., Linderman, R., Hodgson, E., & Rose, R. L. (2000, December 1). Environmental Health Perspectives.

By: S. Coleman*, R. Linderman n, E. Hodgson* & R. Rose*

author keywords: chloroacetamide herbicides; human cytochrome P450; in vitro metabolism
topics (OpenAlex): Pesticide Residue Analysis and Safety; Pesticide Exposure and Toxicity
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2. Zero Hunger (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1999 article

In vitro metabolism of alachlor by human liver microsomes and human cytochrome P450 isoforms

Coleman, S., Liu, S., Linderman, R., Hodgson, E., & Rose, R. L. (1999, August 1). Chemico-Biological Interactions.

By: S. Coleman*, S. Liu  n, R. Linderman n, E. Hodgson n & R. Rose n

author keywords: alachlor; CDEPA; human CYP; herbicides
MeSH headings : Acetamides / metabolism; Animals; Cytochrome P-450 Enzyme System / metabolism; Female; Herbicides / metabolism; Humans; In Vitro Techniques; Isoenzymes / metabolism; Male; Mice; Mice, Inbred Strains; Microsomes, Liver / metabolism; Rats; Rats, Long-Evans
topics (OpenAlex): Pharmacogenetics and Drug Metabolism; Carcinogens and Genotoxicity Assessment; Pesticide Exposure and Toxicity
TL;DR: It is demonstrated that male human liver microsomes are able to metabolize alachlor to CDEPA, a widely used pre-emergent chloroacetanilide herbicide which has been classified by the USEPA as a probable human carcinogen and 2,6-diethylbenzoquinone imine (DEBQI), a putative carcinogenic metabolite. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Flavin-containing monooxygenase and cytochrome P450 mediated metabolism of pesticides: from mouse to human

Reviews in Toxicology, 2(1998), 231–243.

By: E. Hodgson, N. Cherrington, S. Coleman, S. Liu, J. Falls, Y. Cao, J. Goldstein, R. Rose

Source: NC State University Libraries
Added: August 6, 2018

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