Akihiko H. Yamamoto
Works (10)
Updated: August 9th, 2023 21:14
2008 journal article
Neurogenetic networks for startle-induced locomotion in Drosophila melanogaster
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 105(34), 12393–12398.
author keywords: behavioral genetics; epistasis; sensorimotor integration; startle behavior; P-element insertional mutagenesis
MeSH headings : Animals; DNA Transposable Elements; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Epistasis, Genetic; Gene Regulatory Networks / physiology; Locomotion / genetics; Locomotion / physiology; Mutation; Nervous System Physiological Phenomena; Reflex, Startle / genetics; Reflex, Startle / physiology
TL;DR:
It is found that behavioral and neuroanatomical phenotypes are determined by a common set of genes that are organized as partially overlapping genetic networks.
(via Semantic Scholar)
open access via www.pnas.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Pleiotropic effects of Drosophila neuralized on complex behaviors and brain structure
GENETICS, 179(3), 1327–1336.
MeSH headings : Alleles; Alternative Splicing / genetics; Animals; Behavior; Brain / anatomy & histology; DNA Transposable Elements; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Female; Gene Expression Regulation, Developmental; Genes, Insect; Male; Mutagenesis, Insertional; Mutation / genetics; RNA, Messenger / genetics; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Ubiquitin-Protein Ligases / genetics; Ubiquitin-Protein Ligases / metabolism
TL;DR:
The diverse phenotypic effects arising from nearby P-element insertions in neur provide a new appreciation of the concept of allelic effects on phenotype, in which the wild type and null mutant are at the extreme ends of a continuum of pleiotropic allelic Effects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
The early developmental gene Semaphorin 5c contributes to olfactory behavior in adult Drosophila
GENETICS, 176(2), 947–956.
MeSH headings : Aging / physiology; Animals; Animals, Genetically Modified; Antibodies, Monoclonal; Avoidance Learning; Behavior, Animal; Benzaldehydes; Cell Adhesion Molecules, Neuronal / immunology; Crosses, Genetic; Drosophila Proteins / genetics; Drosophila melanogaster / genetics; Drosophila melanogaster / growth & development; Drosophila melanogaster / physiology; Gene Expression Regulation, Developmental; Membrane Glycoproteins / genetics; Mutation; Odorants; Semaphorins / genetics; Smell / physiology
TL;DR:
The results demonstrate how hypomorphic mutation of an early developmental gene results in genomewide transcriptional consequences and alterations in brain structure accompanied by profound impairment of adult behavior.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster
GENETICS, 174(3), 1349–1363.
MeSH headings : Animals; Behavior, Animal; DNA Transposable Elements / genetics; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Epistasis, Genetic; Genes, Insect; Mutagenesis, Insertional; Mutation; Odorants; Smell / genetics; Smell / physiology
TL;DR:
The results show that the manifestation of epistatic networks dynamically changes with alterations in the environment, and surprisingly, epistatic interactions shifted with changes in the concentration of the olfactory stimulus.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
Pleiotropic fitness effects of the Tre1-Gr5a region in Drosophila melanogaster
NATURE GENETICS, 38(7), 824–829.
MeSH headings : Animals; DNA Transposable Elements / genetics; DNA, Intergenic / genetics; Drosophila Proteins / genetics; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Epistasis, Genetic; Female; Genes, Insect; Insulin / metabolism; Longevity / genetics; Male; Mutation; Phenotype; Quantitative Trait, Heritable; Receptors, Cell Surface / genetics; Receptors, G-Protein-Coupled / genetics; Repetitive Sequences, Nucleic Acid; Signal Transduction; Taste / genetics
TL;DR:
It is demonstrated that single P-element insertions in the intergenic region between the gustatory receptor 5a and trapped in endoderm 1, which encodes an orphan receptor, exert complex pleiotropic effects on fitness traits, including selective nutrient intake, life span, and resistance to starvation and heat stress.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Quantitative trait loci affecting starvation resistance in Drosophila melanogaster
GENETICS, 166(4), 1807–1823.
MeSH headings : Analysis of Variance; Animals; Crosses, Genetic; DNA Transposable Elements / genetics; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Genes, Insect / genetics; Genes, Insect / physiology; Genetic Complementation Test; Genetic Variation; Mutation / genetics; Quantitative Trait Loci; Starvation / genetics
TL;DR:
The genes identified are involved in oogenesis, metabolism, and feeding behaviors, indicating a possible link to reproduction and survival, and also imply that resource allocation during development and at the cellular level may also influence the phenotypic response to starvation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
The DSC1 channel, encoded by the smi60E locus, contributes to odor-guided behavior in Drosophila melanogaster
Genetics, 161(4), 1507–1516.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Epistatic interactions attenuate mutations affecting startle behaviour in Drosophila melanogaster
Yamamoto, A., Anholt, R. R. H., & Mackay, T. F. C. Genetical Research, 91(6), 373–382.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Overexpression of myocilin in the Drosophila eye activates the unfolded protein response: Implications for glaucoma
Carbone, M. A., Ayroles, J. F., Yamamoto, A., Morozova, T. V., West, S. A., Magwire, M. M., … Anholt, R. R. H. PLoS One, 4(1).
Source: NC State University Libraries
Added: August 6, 2018
journal article
Quantitative genomics of locomotor behavior in Drosophila melanogaster
Jordan, K. W., Carbone, M. A., Yamamoto, A., Morgan, T. J., & Mackay, T. F. Genome Biology, 8(8).
Source: NC State University Libraries
Added: August 6, 2018
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