Works (2)
Updated: November 3rd, 2025 23:44
2007 article
Synthesis, Stability, and Cellular Internalization of Gold Nanoparticles Containing Mixed Peptide−Poly(ethylene glycol) Monolayers
Liu, Y., Shipton, M. K., Ryan, J., Kaufman, E. D., Franzen, S., & Feldheim, D. L. (2007, February 9). Analytical Chemistry, Vol. 79, pp. 2221–2229.
MeSH headings : Amino Acid Sequence; Endocytosis; Gold / chemistry; HeLa Cells; Humans; Molecular Structure; Molecular Weight; Nanoparticles / chemistry; Peptides / chemical synthesis; Peptides / chemistry; Polyethylene Glycols / chemistry; Spectrometry, Fluorescence; Sulfhydryl Compounds / chemistry
topics (OpenAlex): Advanced biosensing and bioanalysis techniques; Quantum Dots Synthesis And Properties; RNA Interference and Gene Delivery
TL;DR:
The assembly of poly(ethylene glycol) (PEG) and mixed peptide/PEG monolayers on gold nanoparticle surfaces is described to provide useful cues in the assembly of stable peptides/gold nanoparticle bioconjugates capable of being internalized into cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2004 article
Cellular Trajectories of Peptide-Modified Gold Particle Complexes: Comparison of Nuclear Localization Signals and Peptide Transduction Domains
Tkachenko, A. G., Xie, H., Liu, Y., Coleman, D., Ryan, J., Glomm, W. R., … Feldheim, D. L. (2004, April 28). Bioconjugate Chemistry.
MeSH headings : 3T3 Cells; Animals; Biological Transport, Active / physiology; Cell Line, Tumor; Cell Nucleus / drug effects; Cell Nucleus / metabolism; Gene Products, tat / chemistry; Gold / chemistry; Gold / pharmacokinetics; HeLa Cells; Humans; Macromolecular Substances; Mice; Nuclear Localization Signals / drug effects; Nuclear Localization Signals / metabolism; Peptides / chemistry; Peptides / pharmacokinetics; Protein Structure, Tertiary / physiology; Serum Albumin, Bovine / chemistry; Serum Albumin, Bovine / pharmacokinetics; Temperature; Transduction, Genetic
topics (OpenAlex): RNA Interference and Gene Delivery; Advanced biosensing and bioanalysis techniques; Immunotherapy and Immune Responses
TL;DR:
Video-enhanced color differential interference contrast microscopy and transmission electron microscopy indicated that transport of nanoparticles into the cytoplasm and nucleus depends on peptide sequence and cell line, and cellular uptake of Tat PTD peptide-gold nanoparticle conjugates was temperature dependent, suggesting an endosomal pathway of uptake.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018