Lauren Brenna Gilvey

Works (5)

Updated: July 11th, 2023 20:10

2009 journal article

Characterization of Dehaloperoxidase Compound ES and Its Reactivity with Trihalophenols†

Biochemistry, 48(5), 995–1005.

By: J. Feducia n , R. Dumarieh n, L. Gilvey n, T. Smirnova n , S. Franzen n  & R. Ghiladi n 

Contributors: J. Feducia n , R. Dumarieh n, L. Gilvey n, T. Smirnova n , S. Franzen n  & R. Ghiladi n 

MeSH headings : Animals; Binding Sites; Chlorophenols / chemistry; Chlorophenols / metabolism; Crystallography, X-Ray; Cytochrome-c Peroxidase / chemistry; Cytochrome-c Peroxidase / metabolism; Electron Transport Complex IV / chemistry; Electron Transport Complex IV / metabolism; Hemoglobins / chemistry; Hemoglobins / metabolism; Peroxidases / chemistry; Peroxidases / metabolism; Polychaeta / enzymology
TL;DR: It is demonstrated that the first detectable intermediate following the addition of hydrogen peroxide to ferric DHP contains both a ferryl heme and a tyrosyl radical, analogous to Compound ES of cytochrome c peroxidase. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2006 journal article

Proximal cavity, distal histidine, and substrate hydrogen-bonding mutations modulate the activity of Amphitrite ornata dehaloperoxidase

BIOCHEMISTRY, 45(30), 9085–9094.

By: S. Franzen n , J. Belyea n, L. Gilvey n, M. Davis n, C. Chaudhary n, T. Sit n , S. Lommel n

Contributors: S. Franzen n , J. Belyea n, L. Gilvey n, M. Davis n, C. Chaudhary n, T. Sit n , S. Lommel n

MeSH headings : Animals; Binding Sites / genetics; Hemoglobins; Histidine / chemistry; Histidine / genetics; Hydrogen Bonding; Mutagenesis, Site-Directed; Peroxidases / chemistry; Peroxidases / genetics; Peroxidases / metabolism; Phenylalanine / genetics; Polychaeta / enzymology; Polychaeta / genetics; Substrate Specificity / genetics; Tyrosine / genetics; Valine / genetics
TL;DR: The role of tyrosine 38 (Y38), which hydrogen bonds to the hydroxyl group of the substrate, was probed and it was suggested that abolishing this hydrogen bond may open a pathway for the escape of the one-electron product, the phenoxy radical leading to polymeric products. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2006 journal article

The pH dependence of the activity of dehaloperoxidase from Amphitrite ornata

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 1774(1), 121–130.

By: S. Franzen n , L. Gilvey n & J. Belyea n

author keywords: peroxidase; Fourier-transform infrared spectroscopy; X-ray crystallography; enzyme kinetics
MeSH headings : Animals; Crystallography, X-Ray; Hemoglobins / metabolism; Hydrogen-Ion Concentration; Kinetics; Peroxidases / metabolism; Phenols / metabolism; Polychaeta / enzymology; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared
TL;DR: A study of the pH dependence of the activity of DHP reveals a substantial difference in mechanism, and other known peroxidases, which oxidize substrates at the heme edge are discussed by comparison. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Enzyme function of the globin dehaloperoxidase from Amphitrite ornata is activated by substrate binding

BIOCHEMISTRY, 44(48), 15637–15644.

By: J. Belyea n, L. Gilvey n, M. Davis n, M. Godek n, T. Sit n , S. Lommel n, S. Franzen n 

Contributors: J. Belyea n, L. Gilvey n, M. Davis n, M. Godek n, T. Sit n , S. Lommel n, S. Franzen n 

MeSH headings : Animals; Cloning, Molecular; Enzyme Activation; Escherichia coli / enzymology; Escherichia coli / genetics; Globins / metabolism; Hemoglobins; Hydrogen Peroxide / metabolism; Peroxidases / antagonists & inhibitors; Peroxidases / genetics; Peroxidases / metabolism; Phenols / metabolism; Polychaeta / enzymology; Protein Binding; Recombinant Proteins / isolation & purification; Recombinant Proteins / metabolism
TL;DR: The present study shows that, unlike other known peroxidases, DHP activity requires the addition of substrate, TBP, prior to the cosubstrate, peroxide. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2004 journal article

Characterization of single- and double-stranded DNA on gold surfaces

LANGMUIR, 20(25), 11134–11140.

By: S. Moses n, S. Brewer n, L. Lowe n, S. Lappi n, L. Gilvey n, M. Sauthier n, R. Tenent n, D. Feldheim n, S. Franzen n 

MeSH headings : DNA / chemistry; Gold / chemistry; Surface Properties; Temperature; Time Factors
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.