Works (3)

Updated: July 7th, 2023 21:13

2019 journal article

Genome-wide DNA copy number analysis and targeted transcriptional analysis of canine histiocytic malignancies identifies diagnostic signatures and highlights disruption of spindle assembly complex

CHROMOSOME RESEARCH, 27(3), 179–202.

By: K. Kennedy n, R. Thomas n, J. Durrant n, T. Jiang n, A. Motsinger-Reif n & M. Breen n

author keywords: Histiocytic sarcoma; Chromothripsis; MMP9; Aurora kinase; Dendritic cell sarcoma
MeSH headings : Animals; Chromosome Disorders; DNA Copy Number Variations / genetics; Dog Diseases / diagnosis; Dog Diseases / genetics; Dogs; Gene Expression Profiling; Genome / genetics; Histiocytic Disorders, Malignant / diagnosis; Histiocytic Disorders, Malignant / genetics; Histiocytic Disorders, Malignant / veterinary; Humans; Immunohistochemistry / methods; Matrix Metalloproteinase 9 / metabolism; Spindle Apparatus / pathology
Source: Web Of Science
Added: September 30, 2019

2017 journal article

Integrated immunohistochemical and DNA copy number profiling analysis provides insight into the molecular pathogenesis of canine follicular lymphoma

VETERINARY AND COMPARATIVE ONCOLOGY, 15(3), 852–867.

By: R. Thomas n, Z. Demeter*, K. Kennedy n, L. Borst n, K. Singh*, V. Valli, K. Le Boedec*, M. Breen n

author keywords: BCL2; canine; comparative genomic hybridization; fluorescence in situ hybridization; follicular lymphoma; immunohistochemistry
MeSH headings : Animals; DNA Copy Number Variations / genetics; DNA Fingerprinting / veterinary; Dog Diseases / etiology; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Female; Genome-Wide Association Study / veterinary; Lymphoma, Follicular / etiology; Lymphoma, Follicular / genetics; Lymphoma, Follicular / pathology; Lymphoma, Follicular / veterinary; Male; Risk Factors
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

BRAF Mutations in Canine Cancers

PLOS ONE, 10(6).

By: H. Mochizuki n, K. Kennedy n, S. Shapiro n & M. Breen n

MeSH headings : Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Dogs; Exons / genetics; Female; Genetic Predisposition to Disease; Humans; Male; Molecular Sequence Data; Mutation / genetics; Neoplasms / genetics; Neoplasms / veterinary; Proto-Oncogene Proteins B-raf / chemistry; Proto-Oncogene Proteins B-raf / genetics; Sequence Analysis, DNA
Sources: Web Of Science, ORCID
Added: August 6, 2018