Works (3)

Updated: July 5th, 2023 15:52

2011 journal article

Dietary Calcium Restriction Affects Mesenchymal Stem Cell Activity and Bone Development in Neonatal Pigs

JOURNAL OF NUTRITION, 141(3), 373–379.

By: A. Mahajan n, L. Alexander n, B. Seabolt n, D. Catrambone*, J. McClung*, J. Odle n, T. Pfeiler n, E. Loboa n, C. Stahl n

Contributors: A. Mahajan n, L. Alexander n, B. Seabolt n, D. Catrambone*, J. McClung*, J. Odle n, T. Pfeiler n, E. Loboa n, C. Stahl n

MeSH headings : 25-Hydroxyvitamin D3 1-alpha-Hydroxylase / genetics; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase / metabolism; Animals; Animals, Newborn; Bone Density; Bone Development; Bone and Bones / chemistry; Calcitriol / blood; Calcium / blood; Calcium / deficiency; Calcium, Dietary / administration & dosage; Cell Differentiation; Cell Proliferation; Cells, Cultured; Female; Gene Expression Regulation; Male; Mechanical Phenomena; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / metabolism; Nutritional Status; Parathyroid Hormone / blood; RNA, Messenger / metabolism; Receptors, Calcium-Sensing / genetics; Receptors, Calcium-Sensing / metabolism; Sus scrofa
TL;DR: The results indicate that neonatal Ca nutrition is crucial for bone integrity and suggest that early-life Ca restriction may have long-term effects on bone integrity via programming of MSC. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

Dietary Phosphate Restriction Decreases Stem Cell Proliferation and Subsequent Growth Potential in Neonatal Pigs

JOURNAL OF NUTRITION, 140(3), 477–482.

By: L. Alexander n, A. Mahajan n, J. Odle n, K. Flann*, R. Rhoads* & C. Stahl n

Contributors: L. Alexander n, A. Mahajan n, J. Odle n, K. Flann*, R. Rhoads* & C. Stahl n

MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Bone Density / drug effects; Bone Marrow / drug effects; Bone Marrow / metabolism; Cell Proliferation / drug effects; Diet / veterinary; Female; Kidney / drug effects; Kidney / metabolism; Male; Mesenchymal Stem Cells / drug effects; Phosphorus / deficiency; Phosphorus, Dietary / pharmacology; Swine / growth & development; Weight Gain / drug effects
TL;DR: Data indicate that in addition to reductions in muscle and bone growth, dietary PO(4) affects proliferation of tissue-specific stem cells in vivo, which may have profound implications for life-long growth potential. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2008 journal article

Response to dietary phosphorus deficiency is affected by genetic background in growing pigs

JOURNAL OF ANIMAL SCIENCE, 86(10), 2585–2595.

By: L. Alexander n, A. Qu*, S. Cutler*, A. Mahajan n, S. Lonergan*, M. Rothschild*, T. Weber, B. Kerr, C. Stahl n

author keywords: bone; meat quality; phosphorus; pig
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Body Composition / drug effects; Body Composition / genetics; Bone Density; Diet / veterinary; Female; Gene Expression Regulation; Kidney / metabolism; Meat / standards; Phosphorus / deficiency; Phosphorus, Dietary / pharmacology; Swine / genetics; Swine / growth & development
TL;DR: Different mechanisms of P utilization between these genetic lines are indicated, which may lead to strategies to increase efficiency of growth in a more environmentally friendly manner. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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