Chad Harmon Stahl

Works (16)

Updated: January 2nd, 2024 09:02

2023 article

Intestinal Oxidative Damages By F18+<i>Escherichia Coli </i>and Its Amelioration with an Antibacterial Bacitracin Fed to Nursery Pigs

Duarte, M. E. E., Stahl, C., & Kim, S. W. (2023, November 6). JOURNAL OF ANIMAL SCIENCE, Vol. 101, pp. 185–186.

By: M. Duarte n , C. Stahl n & S. Kim n 

author keywords: F18+E. coli; oxidative damages; pigs
TL;DR: F18+E. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: December 11, 2023

2014 journal article

Dietary Calcium Deficiency and Excess Both Impact Bone Development and Mesenchymal Stem Cell Lineage Priming in Neonatal Piglets

JOURNAL OF NUTRITION, 144(12), 1935–1942.

By: Y. Li n & C. Stahl n

author keywords: calcium; swine; mesenchymal stem cells; neonate; differentiation potential
MeSH headings : Adipocytes / drug effects; Animals; Animals, Newborn; Bone Development / drug effects; Calcium / deficiency; Calcium, Dietary / administration & dosage; Calcium, Dietary / blood; Cell Differentiation / drug effects; Cell Lineage / drug effects; Creatinine / urine; Diet; Dose-Response Relationship, Drug; Fatty Acid-Binding Proteins / genetics; Fatty Acid-Binding Proteins / metabolism; Female; Male; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / drug effects; Osteocalcin / genetics; Osteocalcin / metabolism; Osteogenesis / drug effects; PPAR gamma / genetics; PPAR gamma / metabolism; Parathyroid Hormone / blood; RNA, Messenger / genetics; RNA, Messenger / metabolism; Swine
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Dietary supplementation of Bifidobacterium longum strain AH1206 increases its cecal abundance and elevates intestinal interleukin-10 expression in the neonatal piglet

Food and Chemical Toxicology, 60, 116–122.

By: T. Herfel n, S. Jacobi n, X. Lin n, Z. Jouni*, M. Chichlowski *, C. Stahl n, J. Odle n 

Contributors: T. Herfel n, S. Jacobi n, X. Lin n, Z. Jouni*, M. Chichlowski *, C. Stahl n, J. Odle n 

author keywords: Bifidobacteria; Probiotic; Infant; Intestinal health; Immune system; IL-10
MeSH headings : Animal Feed / microbiology; Animals; Animals, Newborn; Bifidobacterium; Cecum / microbiology; Colony Count, Microbial; Dietary Supplements; Immunoglobulin G / blood; Immunoglobulin M / blood; Interleukin-10 / genetics; Interleukin-10 / metabolism; Probiotics / administration & dosage; Swine; Weight Gain
TL;DR: Dietary supplementation with B. longum (AH1206) may be safe for human infants based on a lack of growth, development or deleterious immune-related effects observed in piglets, based on findings in the suckling piglet model. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

The Suckling Piglet as an Agrimedical Model for the Study of Pediatric Nutrition and Metabolism

Annual Review of Animal Biosciences, 2(1), 419–444.

By: J. Odle n , X. Lin n, S. Jacobi n, S. Kim n  & C. Stahl n

Contributors: J. Odle n , X. Lin n, S. Jacobi n, S. Kim n  & C. Stahl n

author keywords: agrimedical; milk; infant; fatty acid; oligosaccharide; amino acid; calcium; phosphorous
MeSH headings : Animal Nutritional Physiological Phenomena; Animals; Animals, Suckling; Child; Child Nutritional Physiological Phenomena; Humans; Swine / physiology
TL;DR: The broad scope of this review is to outline the fundamental elements of the piglet model and to highlight key aspects of relevance to various macronutrients, including lipids, carbohydrates, proteins/amino acids, and calcium/phosphorus. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Sublethal Staphylococcal Enterotoxin B Challenge Model in Pigs To Evaluate Protection following Immunization with a Soybean-Derived Vaccine

CLINICAL AND VACCINE IMMUNOLOGY, 20(1), 24–32.

By: L. Hudson*, B. Seabolt n, J. Odle n , K. Bost*, C. Stahl n & K. Piller*

Contributors: L. Hudson*, B. Seabolt n, J. Odle n , K. Bost*, C. Stahl n & K. Piller*

MeSH headings : Animals; Antibodies, Bacterial / blood; Antibodies, Neutralizing / blood; Antitoxins / blood; Disease Models, Animal; Drug Stability; Drug Storage; Enterotoxins / immunology; Enterotoxins / toxicity; Male; Neutralization Tests; Plants, Genetically Modified / genetics; Poisoning / pathology; Poisoning / prevention & control; Soybeans / genetics; Staphylococcal Vaccines / administration & dosage; Staphylococcal Vaccines / genetics; Staphylococcal Vaccines / immunology; Staphylococcal Vaccines / isolation & purification; Swine; Vaccines, Synthetic / administration & dosage; Vaccines, Synthetic / genetics; Vaccines, Synthetic / immunology; Vaccines, Synthetic / isolation & purification
TL;DR: The potential for soybean-derived proteins as a platform technology for sustainable vaccine manufacturing and the usefulness of a sublethal challenge model in pigs for evaluating the efficacy of potential SEB vaccine candidates are demonstrated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2011 journal article

Dietary Calcium Restriction Affects Mesenchymal Stem Cell Activity and Bone Development in Neonatal Pigs

JOURNAL OF NUTRITION, 141(3), 373–379.

By: A. Mahajan n, L. Alexander n, B. Seabolt n, D. Catrambone*, J. McClung *, J. Odle n , T. Pfeiler n, E. Loboa n, C. Stahl n

Contributors: A. Mahajan n, L. Alexander n, B. Seabolt n, D. Catrambone*, J. McClung *, J. Odle n , T. Pfeiler n, E. Loboa n, C. Stahl n

MeSH headings : 25-Hydroxyvitamin D3 1-alpha-Hydroxylase / genetics; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase / metabolism; Animals; Animals, Newborn; Bone Density; Bone Development; Bone and Bones / chemistry; Calcitriol / blood; Calcium / blood; Calcium / deficiency; Calcium, Dietary / administration & dosage; Cell Differentiation; Cell Proliferation; Cells, Cultured; Female; Gene Expression Regulation; Male; Mechanical Phenomena; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / metabolism; Nutritional Status; Parathyroid Hormone / blood; RNA, Messenger / metabolism; Receptors, Calcium-Sensing / genetics; Receptors, Calcium-Sensing / metabolism; Sus scrofa
TL;DR: The results indicate that neonatal Ca nutrition is crucial for bone integrity and suggest that early-life Ca restriction may have long-term effects on bone integrity via programming of MSC. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

Dietary Phosphate Restriction Decreases Stem Cell Proliferation and Subsequent Growth Potential in Neonatal Pigs

JOURNAL OF NUTRITION, 140(3), 477–482.

By: L. Alexander n, A. Mahajan n, J. Odle n , K. Flann*, R. Rhoads * & C. Stahl n

Contributors: L. Alexander n, A. Mahajan n, J. Odle n , K. Flann*, R. Rhoads * & C. Stahl n

MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Bone Density / drug effects; Bone Marrow / drug effects; Bone Marrow / metabolism; Cell Proliferation / drug effects; Diet / veterinary; Female; Kidney / drug effects; Kidney / metabolism; Male; Mesenchymal Stem Cells / drug effects; Phosphorus / deficiency; Phosphorus, Dietary / pharmacology; Swine / growth & development; Weight Gain / drug effects
TL;DR: Data indicate that in addition to reductions in muscle and bone growth, dietary PO(4) affects proliferation of tissue-specific stem cells in vivo, which may have profound implications for life-long growth potential. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

Evaluation of Phage Treatment as a Strategy to Reduce Salmonella Populations in Growing Swine

FOODBORNE PATHOGENS AND DISEASE, 8(2), 261–266.

By: T. Callaway *, T. Edrington*, A. Brabban*, B. Kutter*, L. Karriker *, C. Stahl n, E. Wagstrom*, R. Anderson * ...

MeSH headings : Animal Husbandry / methods; Animals; Bacterial Shedding; Bacteriolysis; Cecum / microbiology; Colony Count, Microbial / veterinary; Feces / microbiology; Gastrointestinal Contents / microbiology; Humans; Microbial Viability; Pest Control, Biological / methods; Rectum / microbiology; Salmonella Food Poisoning / prevention & control; Salmonella Infections, Animal / microbiology; Salmonella Infections, Animal / prevention & control; Salmonella Infections, Animal / virology; Salmonella Phages / physiology; Salmonella typhimurium / growth & development; Salmonella typhimurium / isolation & purification; Salmonella typhimurium / physiology; Salmonella typhimurium / virology; Sus scrofa / growth & development; Sus scrofa / microbiology; Sus scrofa / virology; Time Factors
TL;DR: The number of pigs that contained inoculated Salmonella Typhimurium was reduced by phage treatment, but a significant reduction was only observed in the rectum, and further research needs to be performed to determine the most efficacious dosing regimens and the most effective combinations of phages targeting the diverseSalmonella population found in swine before they can enter the food supply. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Occurrence of Salmonella-Specific Bacteriophages in Swine Feces Collected from Commercial Farms

FOODBORNE PATHOGENS AND DISEASE, 7(7), 851–856.

By: T. Callaway *, T. Edrington*, A. Brabban*, E. Kutter *, L. Karriker *, C. Stahl n, E. Wagstrom*, R. Anderson * ...

MeSH headings : Agglutination Tests; Animal Husbandry / methods; Animals; Coliphages / growth & development; Coliphages / isolation & purification; Escherichia coli / growth & development; Escherichia coli / virology; Feces / microbiology; Feces / virology; Microbial Viability; Pest Control, Biological / methods; Salmonella / classification; Salmonella / growth & development; Salmonella / isolation & purification; Salmonella / virology; Salmonella Food Poisoning / prevention & control; Salmonella Phages / growth & development; Salmonella Phages / isolation & purification; Salmonella typhimurium / classification; Salmonella typhimurium / growth & development; Salmonella typhimurium / isolation & purification; Salmonella typhimurium / virology; Serotyping; Species Specificity; Sus scrofa / microbiology; Sus scrofa / virology; Viral Plaque Assay
TL;DR: The results indicate that bacteriophages are widespread in commercial swine, but those capable of killing Salmonella Typhimurium may be present at relatively low population levels; and that phages could potentially be used as a food safety pathogen reduction strategy in swine. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Oral Vaccine Formulations Stimulate Mucosal and Systemic Antibody Responses against Staphylococcal Enterotoxin B in a Piglet Model

CLINICAL AND VACCINE IMMUNOLOGY, 17(8), 1163–1169.

By: T. Inskeep*, C. Stahl n, J. Odle n , J. Oakes *, L. Hudson*, K. Bost*, K. Piller*

Contributors: T. Inskeep*, C. Stahl n, J. Odle n , J. Oakes *, L. Hudson*, K. Bost*, K. Piller*

MeSH headings : Adjuvants, Immunologic / administration & dosage; Administration, Oral; Amino Acid Substitution / genetics; Animals; Animals, Newborn; Antibodies, Bacterial / blood; Antitoxins / blood; Cholera Toxin / administration & dosage; Enterotoxins / administration & dosage; Enterotoxins / immunology; Enterotoxins / toxicity; Feces / chemistry; Female; Humans; Immunity, Mucosal; Immunization, Secondary / methods; Immunoglobulin A / analysis; Immunoglobulin G / blood; Male; Mutant Proteins / administration & dosage; Mutant Proteins / immunology; Mutant Proteins / toxicity; Mutation, Missense; Staphylococcal Vaccines / administration & dosage; Staphylococcal Vaccines / adverse effects; Staphylococcal Vaccines / immunology; Staphylococcal Vaccines / toxicity; Superantigens / administration & dosage; Superantigens / immunology; Superantigens / toxicity; Swine; Time Factors; Vaccines, Synthetic / administration & dosage; Vaccines, Synthetic / adverse effects; Vaccines, Synthetic / immunology; Vaccines, Synthetic / toxicity
TL;DR: In vitro studies suggested that rmSEB could be a safe subunit vaccine and provide additional evidence for the potential use of nontoxic forms of SEB as vaccines. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

A calcitonin receptor (CALCR) single nucleotide polymorphism is associated with growth performance and bone integrity in response to dietary phosphorus deficiency

JOURNAL OF ANIMAL SCIENCE, 88(3), 1009–1016.

By: L. Alexander n, A. Qu*, S. Cutler*, A. Mahajan n, M. Rothschild*, W. Cai *, J. Dekkers *, C. Stahl n

author keywords: bone; genotype; phosphorus; pig
MeSH headings : Alkaline Phosphatase / blood; Animals; Body Weight / genetics; Body Weight / physiology; Bone and Bones / physiology; Female; Genotype; Phosphorus / blood; Phosphorus / deficiency; Polymorphism, Single Nucleotide / genetics; Polymorphism, Single Nucleotide / physiology; Receptors, Calcitonin / genetics; Receptors, Calcitonin / physiology; Swine / genetics; Swine / growth & development; Swine / physiology
TL;DR: It is demonstrated that genetic background impacts P utilization in young pigs and genetic polymorphisms in several target genes related to mineral utilization are identified, supportive of the association of this CALCR SNP with bone integrity and its response to dietary P restriction. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Dihydroxy-cholecalciferol stimulates adipocytic differentiation of porcine mesenchymal stem cells

JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 20(7), 512–520.

By: A. Mahajan n & C. Stahl*

author keywords: Mesenchymal stem cells; Dihydroxy-cholecalciferol; Pig; Adipogenesis; Osteogenesis
MeSH headings : Adipocytes / cytology; Adipocytes / metabolism; Adipogenesis / drug effects; Animals; Calcitriol / blood; Calcitriol / pharmacology; Cell Differentiation / drug effects; Cell Proliferation / drug effects; Cells, Cultured; Gene Expression / drug effects; Gene Expression Regulation / drug effects; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / drug effects; Mesenchymal Stem Cells / physiology; PPAR gamma / metabolism; RNA, Messenger / metabolism; Swine / blood; Swine / physiology
TL;DR: The data suggest that 1,25(OH)(2)D(3) stimulates the differentiation of porcine MSC towards an adipocytic phenotype, and the concentrations of mRNAs encoding peroxisome proliferator-activated receptor gamma, lipoprotein lipase, and adipocyte-binding protein 2 were increased and decreased, respectively. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2008 article

Introduction to the symposium: Appropriate animal models for nutritional research in health and disease

Stahl, C. H., Lei, X., & Larson, B. (2008, February). JOURNAL OF NUTRITION, Vol. 138, pp. 389–390.

By: C. Stahl n, X. Lei * & B. Larson*

MeSH headings : Animal Nutritional Physiological Phenomena; Animals; Cattle; Humans; Models, Animal; Nutritional Physiological Phenomena; Nutritional Sciences; Swine
TL;DR: This symposium was an opportunity for both animal and human nutrition researchers to meet and discuss and redefine strategies relating to the use of experimental animal nutrition knowledge. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Physical activity prevents augmented body fat accretion in moderately iron-deficient rats

JOURNAL OF NUTRITION, 138(7), 1293–1297.

By: J. McClung *, N. Andersen*, T. Tarr*, C. Stahl n & A. Young *

MeSH headings : Adipose Tissue / anatomy & histology; Animals; Blood Glucose / metabolism; Body Composition; Body Weight; Bone Density; Eating; Humans; Insulin / blood; Iron Deficiencies; Iron, Dietary / administration & dosage; Male; Models, Animal; Models, Biological; Motor Activity / physiology; Rats; Rats, Sprague-Dawley; Running / physiology
TL;DR: After 12 wk, ID rats were not anemic, but body iron stores were reduced as indicated by diminished femur iron, and moderate iron deficiency may cause increased body fat accretion in rats and PA attenuates that effect. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Response to dietary phosphorus deficiency is affected by genetic background in growing pigs

JOURNAL OF ANIMAL SCIENCE, 86(10), 2585–2595.

By: L. Alexander n, A. Qu*, S. Cutler*, A. Mahajan n, S. Lonergan *, M. Rothschild, T. Weber, B. Kerr, C. Stahl n

author keywords: bone; meat quality; phosphorus; pig
MeSH headings : Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Body Composition / drug effects; Body Composition / genetics; Bone Density; Diet / veterinary; Female; Gene Expression Regulation; Kidney / metabolism; Meat / standards; Phosphorus / deficiency; Phosphorus, Dietary / pharmacology; Swine / genetics; Swine / growth & development
TL;DR: Different mechanisms of P utilization between these genetic lines are indicated, which may lead to strategies to increase efficiency of growth in a more environmentally friendly manner. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Dietary inclusion of colicin E1 is effective in preventing postweaning diarrhea caused by F18-positive Escherichia coli in pigs

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 51(11), 3830–3835.

By: S. Cutler*, S. Lonergan *, N. Cornick*, A. Johnson * & C. Stahl n

MeSH headings : Animal Feed; Animals; Body Weight / drug effects; Colicins / administration & dosage; Colicins / pharmacology; Diarrhea / etiology; Diarrhea / prevention & control; Enterotoxigenic Escherichia coli / drug effects; Enterotoxigenic Escherichia coli / metabolism; Escherichia coli Infections / complications; Escherichia coli Infections / microbiology; Escherichia coli Proteins / metabolism; Feces / microbiology; Fimbriae Proteins / metabolism; Gene Expression / drug effects; Ileum / drug effects; Ileum / metabolism; Ileum / microbiology; Interleukin-1beta / genetics; Lymphotoxin-alpha / genetics; Male; Swine; Swine Diseases / etiology; Swine Diseases / prevention & control; Weaning
TL;DR: The dietary inclusion of colicin E1 may be an effective alternative to conventional antibiotics in the diets of weaning pigs for the prevention of PWD caused by F18-positive enterotoxigenic E. coli. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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