Works (7)
Updated: October 1st, 2024 05:03
2024 journal article
MARCKS Inhibition Alters Bovine Neutrophil Responses to <i>Salmonella</i> Typhimurium
BIOMEDICINES, 12(2).
author keywords: neutrophils; Salmonella; MARCKS; respiratory burst; migration; phagocytosis
TL;DR:
This study demonstrates that MARCKS inhibition attenuated STm-induced neutrophil adhesion and chemotaxis and enhanced neutrophil phagocytosis and respiratory burst in response to STm, the first report describing the role of MARCKS protein in neutrophil antibacterial responses.
(via Semantic Scholar)
open access via www.mdpi.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 22, 2024
2024 article
Pathogenic diversification of the gut commensal <i>Providencia alcalifaciens</i> via acquisition of a second type III secretion system
Klein, J. A., Predeus, A. V., Greissl, A. R., Clark-Herrera, M. M., Cruz, E., Cundiff, J. A., … Knodler, L. A. (2024, September 10). INFECTION AND IMMUNITY.
author keywords: type III secretion; virulence; pathogenesis; enteric bacteria; diarrhea
Source: Web Of Science
Added: September 23, 2024
2023 article
Nonredundant Dimethyl Sulfoxide Reductases Influence Salmonella enterica Serotype Typhimurium Anaerobic Growth and Virulence
Cruz, E., Haeberle, A. L., Westerman, T. L., Durham, M. E., Suyemoto, M. M., Knodler, L. A., & Elfenbein, J. R. (2023, February 1). INFECTION AND IMMUNITY.
author keywords: DMSO; Salmonella; anaerobic metabolism; bovine ileal loop model; dimethyl sulfoxide; murine infection; type 3 secretion system
MeSH headings : Animals; Virulence; Anaerobiosis; Type III Secretion Systems / metabolism; Dimethyl Sulfoxide / pharmacology; Dimethyl Sulfoxide / metabolism; Serogroup; Oxidoreductases / metabolism; Salmonella typhimurium; Mammals
TL;DR:
It is demonstrated that an S. enterica serotype Typhimurium mutant with loss of function in all three putative DMSO reductases (ΔdmsA3) poorly colonizes the mammalian intestine when the microbiota is intact and when inflammation is absent, and suggest D MSO is a physiologically relevant electron acceptor that supports S. entersica fitness in the gut.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: March 13, 2023
2021 journal article
Sulfate Import in Salmonella Typhimurium Impacts Bacterial Aggregation and the Respiratory Burst in Human Neutrophils
INFECTION AND IMMUNITY, 89(6).
author keywords: Salmonella; cysteine metabolism; flagellar motility; neutrophils; respiratory burst
MeSH headings : Cysteine / metabolism; Flagella / physiology; Genes, Bacterial; Host-Pathogen Interactions / immunology; Humans; Mutation; Neutrophils / immunology; Neutrophils / metabolism; Respiratory Burst / immunology; Salmonella Infections / immunology; Salmonella Infections / microbiology; Salmonella typhimurium / physiology; Sulfates / metabolism; Type III Secretion Systems / genetics; Type III Secretion Systems / metabolism
TL;DR:
It is demonstrated that Salmonella Typhimurium has numerous mechanisms to limit the magnitude of the neutrophil respiratory burst, and this data further inform the understanding of howSalmonella may alter human neutrophIL antimicrobial defenses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 10, 2021
2021 journal article
YeiE Regulates Motility and Gut Colonization in Salmonella enterica Serotype Typhimurium
MBIO, 12(3).
author keywords: Salmonella; flagellar gene regulation; gastrointestinal infection; host-pathogen interactions; transcriptional regulation
MeSH headings : Animals; Bacterial Proteins / genetics; Cattle; Female; Flagella / genetics; Flagella / physiology; Gastrointestinal Microbiome; Gene Expression; Gene Expression Regulation, Bacterial; Mice; Mice, Inbred C57BL; Movement; Salmonella Infections, Animal / microbiology; Salmonella typhimurium / genetics; Salmonella typhimurium / metabolism; Salmonella typhimurium / pathogenicity; Serogroup; Virulence
TL;DR:
It is indicated that YeiE promotes virulence by enhancing cell motility, thereby providing a new regulatory control point for flagellar expression in Salmonella Typhimurium.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: September 27, 2021
2018 journal article
The Salmonella type-3 secretion system-1 and flagellar motility influence the neutrophil respiratory burst
PLOS ONE, 13(9).
MeSH headings : Fimbriae, Bacterial / physiology; Genotype; Granulocyte-Macrophage Colony-Stimulating Factor / pharmacology; Humans; Interleukin-8 / pharmacology; Neutrophils / cytology; Neutrophils / metabolism; Neutrophils / microbiology; Reactive Oxygen Species / metabolism; Respiratory Burst / drug effects; Salmonella / genetics; Salmonella / metabolism; Type III Secretion Systems / drug effects; Type III Secretion Systems / metabolism
TL;DR:
It is demonstrated that both the type-3 secretion system-1 and flagellar motility, which are established virulence factors in enteric salmonellosis, also appear to directly influence the magnitude of the neutrophil respiratory burst in response to STm in vitro.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 16, 2018
2016 journal article
Evaluation of serum amyloid A and haptoglobin concentrations as prognostic indicators for horses with colic
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 248(8), 935–940.
MeSH headings : Animals; Blood Chemical Analysis / veterinary; Case-Control Studies; Colic / blood; Colic / complications; Colic / veterinary; Haptoglobins / analysis; Hematologic Tests / veterinary; Horse Diseases / blood; Horse Diseases / drug therapy; Horse Diseases / surgery; Horses; Prognosis; Prospective Studies; Serum Amyloid A Protein / analysis
TL;DR:
Horses with colic that had an abnormally increased SAA concentration were more likely to require surgical intervention, develop thrombophlebitis, or be euthanized because of a poor prognosis despite treatment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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