Works (3)
Updated: July 5th, 2023 15:41
2014 journal article
Bio-lnspired Synthetic Nanovesicles for Glucose-Responsive Release of Insulin
BIOMACROMOLECULES, 15(10), 3495–3502.
MeSH headings : Animals; Blood Glucose / drug effects; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Experimental / metabolism; Drug Delivery Systems / methods; Gluconates / chemistry; Glucose / administration & dosage; Glucose / chemistry; Glucose Oxidase / metabolism; Hydrogen-Ion Concentration; Insulin / administration & dosage; Insulin / chemistry; Male; Mice; Mice, Inbred C57BL; Polymers / administration & dosage; Polymers / chemistry
TL;DR:
In vivo experiments demonstrate that a single injection of the developed nanovesicle facilitated stabilization of the blood glucose levels in the normoglycemic state (<200 mg/dL) for up to 5 days.
(via Semantic Scholar)
open access via doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Clickable Protein Nanocapsules for Targeted Delivery of Recombinant p53 Protein
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(43), 15319–15325.
MeSH headings : Amino Acid Sequence; Azides / chemistry; Cell Survival / drug effects; Click Chemistry; Drug Carriers / chemistry; Drug Carriers / metabolism; Drug Carriers / toxicity; Drug Liberation; Gonadotropin-Releasing Hormone / chemistry; HeLa Cells; Humans; Ligands; Nanocapsules / chemistry; Nanocapsules / toxicity; Peptide Fragments / chemistry; Peptide Fragments / metabolism; Polyethylene Glycols / chemistry; Recombinant Proteins / chemistry; Single-Chain Antibodies / chemistry; Single-Chain Antibodies / metabolism; Surface Properties; Tumor Suppressor Protein p53 / chemistry
TL;DR:
The results validate a general approach for targeted protein delivery into tumor cells using cellular-responsive nanocarriers, opening up new opportunities for the development of intracellular protein-based anticancer treatment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Self-folded redox/acid dual-responsive nanocarriers for anticancer drug delivery
CHEMICAL COMMUNICATIONS, 50(95), 15105–15108.
MeSH headings : Antineoplastic Agents / administration & dosage; Antineoplastic Agents / chemistry; Cell Survival / drug effects; Doxorubicin / administration & dosage; Doxorubicin / chemistry; Drug Carriers / administration & dosage; Drug Carriers / chemistry; Folic Acid / administration & dosage; Folic Acid / chemistry; Glutathione / chemistry; HeLa Cells; Humans; Nanoparticles / administration & dosage; Nanoparticles / chemistry; Oxidation-Reduction; Peptides / chemistry; Polyethylene Glycols / chemistry
TL;DR:
Self-folded redox/acid dual-responsive nanocarriers developed for physiologically triggered delivery of anticancer drugs suggest their potential as a promising formulation for tumor-targeted chemotherapy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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