Wanyi Tai

Works (3)

Updated: July 5th, 2023 15:41

2014 journal article

Bio-lnspired Synthetic Nanovesicles for Glucose-Responsive Release of Insulin

BIOMACROMOLECULES, 15(10), 3495–3502.

By: W. Tai n, R. Mo n, J. Di n, V. Subramanian n, X. Gu n, J. Buse *, Z. Gu n

MeSH headings : Animals; Blood Glucose / drug effects; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Experimental / metabolism; Drug Delivery Systems / methods; Gluconates / chemistry; Glucose / administration & dosage; Glucose / chemistry; Glucose Oxidase / metabolism; Hydrogen-Ion Concentration; Insulin / administration & dosage; Insulin / chemistry; Male; Mice; Mice, Inbred C57BL; Polymers / administration & dosage; Polymers / chemistry
TL;DR: In vivo experiments demonstrate that a single injection of the developed nanovesicle facilitated stabilization of the blood glucose levels in the normoglycemic state (<200 mg/dL) for up to 5 days. (via Semantic Scholar)
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6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Clickable Protein Nanocapsules for Targeted Delivery of Recombinant p53 Protein

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(43), 15319–15325.

By: M. Zhao*, Y. Liu *, R. Hsieh*, N. Wang*, W. Tai*, K. Joo*, P. Wang *, Z. Gu*, Y. Tang *

MeSH headings : Amino Acid Sequence; Azides / chemistry; Cell Survival / drug effects; Click Chemistry; Drug Carriers / chemistry; Drug Carriers / metabolism; Drug Carriers / toxicity; Drug Liberation; Gonadotropin-Releasing Hormone / chemistry; HeLa Cells; Humans; Ligands; Nanocapsules / chemistry; Nanocapsules / toxicity; Peptide Fragments / chemistry; Peptide Fragments / metabolism; Polyethylene Glycols / chemistry; Recombinant Proteins / chemistry; Single-Chain Antibodies / chemistry; Single-Chain Antibodies / metabolism; Surface Properties; Tumor Suppressor Protein p53 / chemistry
TL;DR: The results validate a general approach for targeted protein delivery into tumor cells using cellular-responsive nanocarriers, opening up new opportunities for the development of intracellular protein-based anticancer treatment. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Self-folded redox/acid dual-responsive nanocarriers for anticancer drug delivery

CHEMICAL COMMUNICATIONS, 50(95), 15105–15108.

By: Y. Lu n, R. Mo n, W. Tai n, W. Sun n, D. Pacardo n, C. Qian  n, Q. Shen *, F. Ligler n, Z. Gu n

MeSH headings : Antineoplastic Agents / administration & dosage; Antineoplastic Agents / chemistry; Cell Survival / drug effects; Doxorubicin / administration & dosage; Doxorubicin / chemistry; Drug Carriers / administration & dosage; Drug Carriers / chemistry; Folic Acid / administration & dosage; Folic Acid / chemistry; Glutathione / chemistry; HeLa Cells; Humans; Nanoparticles / administration & dosage; Nanoparticles / chemistry; Oxidation-Reduction; Peptides / chemistry; Polyethylene Glycols / chemistry
TL;DR: Self-folded redox/acid dual-responsive nanocarriers developed for physiologically triggered delivery of anticancer drugs suggest their potential as a promising formulation for tumor-targeted chemotherapy. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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