Works Published in 2012

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2012 journal article

Production of prostaglandin E-2 in response to infection with modified vaccinia Ankara virus

VIROLOGY, 428(2), 146–155.

By: J. Pollara*, A. Spesock, D. Pickup, S. Laster* & I. Petty

author keywords: Poxvirus; Vaccine; Lipid mediator; Cyclooxygenase-2; Cytosolic phospholipase A(2); NF-kappa B
MeSH headings : Animals; Arachidonic Acid / metabolism; Cell Line; Cyclooxygenase 2 / genetics; Cyclooxygenase 2 / metabolism; Dinoprostone / metabolism; Humans; Mice; Vaccinia / enzymology; Vaccinia / metabolism; Vaccinia / virology; Vaccinia virus / genetics; Vaccinia virus / physiology; Viral Proteins / genetics; Viral Proteins / metabolism
TL;DR: In this study, PGE₂ production in vitro by cells infected with the poxvirus vaccine strain, modified vaccinia Ankara virus (MVA), is investigated and it is demonstrated that MVA induced the release of AA from infected cells, and this was, most unusually, independent of host cytosolic phospholipase A₁ activity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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