Works Published in 2015
Displaying works 21 - 25 of 25 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2015 journal article
Immuno-modulatory strategies for reduction of HIV reservoir cells
JOURNAL OF THEORETICAL BIOLOGY, 372, 146–158.
author keywords: Immune response; Mathematical model; Inverse problem; Stability analysis
MeSH headings : Anti-HIV Agents / chemistry; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / virology; CD8-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / virology; Cell Proliferation; Computer Simulation; HIV Infections / immunology; HIV Infections / therapy; HIV-1; Homeostasis; Humans; Models, Biological; Viral Load; Virus Latency
TL;DR:
The findings indicate that the strategy of reactivating the reservoir combined with enhancement of the killing rate of HIV-specific CD8+ T cells is able to eradicate the reservoir.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Declining liver graft quality threatens the future of liver transplantation in the United States
Liver Transplantation, 21(8), 1040–1050.
MeSH headings : Adult; Computer Simulation; Databases, Factual; Donor Selection / trends; Female; Forecasting; Graft Survival; Health Care Rationing / trends; Health Services Needs and Demand / trends; Humans; Liver Transplantation / adverse effects; Liver Transplantation / trends; Male; Middle Aged; Models, Theoretical; Needs Assessment; Postoperative Complications / etiology; Process Assessment, Health Care / trends; Reproducibility of Results; Risk Assessment; Risk Factors; Time Factors; Tissue Donors / supply & distribution; Treatment Outcome; United States
TL;DR:
The transplant community will need to accept inferior grafts and potentially worse posttransplant outcomes and/or develop new strategies for increasing organ donation and utilization in order to maintain the number of LTs at the current level.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2015 journal article
Doubly robust learning for estimating individualized treatment with censored data
BIOMETRIKA, 102(1), 151–168.
author keywords: Censored data; Doubly robust estimator; Individualized treatment rule; Risk bound; Support vector machine
TL;DR:
Nonparametric methods for estimating an optimal individualized treatment rule in the presence of censored data are developed and a doubly robust estimator is proposed which requires correct specification of either the censoring model or survival model but not both.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2015 journal article
Estimation of time-varying mortality rates using continuous models for Daphnia magna
APPLIED MATHEMATICS LETTERS, 44, 12–16.
author keywords: Structured population model; Leslie matrix model; Sinko-Streifer model; Daphnia magna; Time-dependent mortality rate
TL;DR:
It is found that a continuous differential equation model with a time-varying mortality rate was the most accurate model for describing the authors' experimental D. magna survival data.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Optimal design of non-equilibrium experiments for genetic network interrogation
APPLIED MATHEMATICS LETTERS, 40, 84–89.
author keywords: Optimal experimental design; Inverse problem; Uncertainty analysis; Brome mosaic virus; Synthetic biology; Genetic networks
TL;DR:
An optimal design algorithm is developed that calculates optimal observation times in conjunction with optimal experimental perturbations in order to maximize the amount of information gained from longitudinal data derived from such experiments.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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