Works Published in 2015

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Displaying works 1 - 20 of 25 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2015 journal article

Trends in BMI and obesity in U.S. women of childbearing age during the period of 1980–2010

Health Systems, 4(3), 176–186.

author keywords: obesity; body mass index; health disparities; simulation
TL;DR: There are differences in weight gain in black and white women, the racial disparity has worsened over time and that changes in theracial disparity were not because of changes inThe age structure of the population. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, ORCID
Added: May 17, 2021

2015 conference paper

Optimal distribution of the influenza vaccine

Proceedings - Winter Simulation Conference, 2015-January, 1411–1420.

By: O. Ozaltin n, O. Dalgic & F. Erenay*

Contributors: O. Ozaltin n, O. Dalgic & F. Erenay*

TL;DR: An agent-based stochastic simulation model is used, and the best policy returned by this approach outperforms alternative policies recommended by the Advisory Committee on Immunization Practices and Centers for Disease Control and Prevention. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: May 6, 2020

2015 journal article

A robust method for estimating optimal treatment regimes

Biometrics, 71, 271–273.

By: B. Zhang*, A. Tsiatis n, E. Laber n & M. Davidian n

MeSH headings : Breast Neoplasms / epidemiology; Breast Neoplasms / therapy; Clinical Trials as Topic / methods; Decision Support Systems, Clinical; Female; Humans; Models, Statistical; Outcome Assessment, Health Care / methods
Sources: Crossref, ORCID
Added: January 27, 2020

2015 chapter

Chapter 9: Value search estimators for optimal dynamic treatment regimes

In Adaptive Treatment Strategies in Practice (pp. 135–155).

By: M. Davidian*, A. Tsiatis & E. Laber

Sources: Crossref, ORCID
Added: January 22, 2020

2015 journal article

Properties of Estimators in Exponential Family Settings with Observationbased Stopping Rules

Journal of Biometrics & Biostatistics, 07(01).

TL;DR: It is established that the ordinary sample average is a very sensible choice, contrary to commonly encountered statements, in the context of outcomes following an exponential family distribution and with a stochastic stopping rule that includes a deterministic rule and completely random sample size as special cases. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 19, 2020

2015 journal article

On sparse representation for optimal individualized treatment selection with penalized outcome weighted learning

Stat, 4(1), 59–68.

author keywords: penalization; personalized medicine; support vector machine
TL;DR: This article develops a variable selection method based on penalized outcome weighted learning through which an optimal treatment rule is considered as a classification problem where each subject is weighted proportional to his or her clinical outcome. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 13, 2020

2015 journal article

Using pilot data to size a two-arm randomized trial to find a nearly optimal personalized treatment strategy

Statistics in Medicine, 35(8), 1245–1256.

author keywords: personalized medicine; sample size calculation; treatment regimes; nonregular asymptotics; projection confidence region
MeSH headings : Biostatistics; Computer Simulation; Confidence Intervals; Data Interpretation, Statistical; Evidence-Based Practice / statistics & numerical data; Female; Fertility; Humans; Male; Models, Statistical; Pilot Projects; Precision Medicine / statistics & numerical data; Pregnancy; Randomized Controlled Trials as Topic / statistics & numerical data; Regression Analysis; Sample Size
TL;DR: This work offers a simple and robust method for powering a single stage, two‐armed randomized clinical trial when the primary aim is estimating the optimal single stage personalized treatment strategy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, ORCID
Added: January 13, 2020

2015 journal article

Correlation of parameter estimators for models admitting multiple parametrizations

International Journal of Pure and Applied Mathematics, 105(3), 497–522.

By: K. Adoteye n, R. Baraldi, K. Flores, J. Nardini, H. Banks & W. Thompson

Source: Crossref
Added: August 18, 2019

2015 journal article

Optimal design for minimizing uncertainty in dynamic equilibrium systems

Eurasian Journal of Mathematical and Computer Applications, 3(1), 23–47.

By: H. Banks, R. Baraldi & K. Flores

Source: NC State University Libraries
Added: July 10, 2019

2015 journal article

Exact solution approach for a class of nonlinear bilevel knapsack problems

JOURNAL OF GLOBAL OPTIMIZATION, 61(2), 291–310.

By: B. Beheshti*, O. Ozaltin, M. Zare* & O. Prokopyev*

author keywords: Bilevel programming; Integer programming; Value functions; Knapsack problem
TL;DR: An exact solution approach is proposed using an equivalent single-level value function reformulation for nonlinear bilevel knapsack problems with quadratic and fractional binary objective functions. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Using Decision Lists to Construct Interpretable and Parsimonious Treatment Regimes

BIOMETRICS, 71(4), 895–904.

author keywords: Decision lists; Exploratory analyses; Interpretability; Personalized medicine; Treatment regimes
MeSH headings : Biometry / methods; Breast Neoplasms / drug therapy; Clinical Protocols; Clinical Trials as Topic / statistics & numerical data; Computer Simulation; Decision Trees; Depression / therapy; Evidence-Based Medicine / statistics & numerical data; Female; Humans; Models, Statistical; Precision Medicine / statistics & numerical data
TL;DR: A simple, yet flexible class of treatment regimes whose members are representable as a short list of if–then statements are proposed, which are immediately interpretable and are therefore an appealing choice for broad application in practice. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Estimation After a Group Sequential Trial

STATISTICS IN BIOSCIENCES, 7(2), 187–205.

By: E. Milanzi*, G. Molenberghs*, A. Alonso*, M. Kenward*, A. Tsiatis n, M. Davidian n, G. Verbeke*

author keywords: Exponential family; Frequentist inference; Generalized sample average; Joint modeling; Likelihood inference; Missing at random; Sample average
TL;DR: It is shown that the ordinary sample average is a viable option for estimation following a group sequential trial, for a wide class of stopping rules and for random outcomes with a distribution in the exponential family, and it is consistent and asymptotically unbiased. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Structured estimation for the nonparametric Cox model

ELECTRONIC JOURNAL OF STATISTICS, 9(1), 492–534.

By: J. Bradic* & R. Song n

TL;DR: Theoretical properties of the non-parametric Cox proportional hazards model in a high dimensional non-asymptotic setting are studied and it is shown that bounded effects can lead to prediction bounds similar to the simple linear models, whereas unbounded effects can leads to larger prediction bounds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

UNCERTAINTY QUANTIFICATION IN MODELING HIV VIRAL MECHANICS

MATHEMATICAL BIOSCIENCES AND ENGINEERING, 12(5), 937–964.

MeSH headings : Algorithms; Anti-HIV Agents / therapeutic use; CD4-Positive T-Lymphocytes / virology; Clinical Trials as Topic; HIV Infections / drug therapy; HIV Infections / physiopathology; HIV Infections / virology; HIV-1 / physiology; Humans; Least-Squares Analysis; Models, Biological; Models, Statistical; RNA, Viral / analysis; Reverse Transcriptase Inhibitors / therapeutic use; Uncertainty; Viral Load
TL;DR: An in-host model for HIV-1 infection dynamics developed and validated with patient data in earlier work is considered and Bootstrapping and asymptotic theory are compared in the context of confidence intervals for the resulting parameter estimates. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Predicting Liver Transplant Capacity Using Discrete Event Simulation

MEDICAL DECISION MAKING, 35(6), 784–796.

author keywords: liver transplantation; organ donors; forecast; simulation
MeSH headings : Computer Simulation; Forecasting; Health Services Accessibility / statistics & numerical data; Health Services Accessibility / trends; Health Services Needs and Demand / statistics & numerical data; Health Services Needs and Demand / trends; Humans; Liver Transplantation / statistics & numerical data; Liver Transplantation / trends; Tissue Donors / supply & distribution; Tissue Survival; United States; Waiting Lists
TL;DR: A discrete event simulation model informed by current donor characteristics to predict future LT trends through the year 2030 can be used to develop policy interventions to prevent a further decline in this lifesaving therapy. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Penalized q-learning for dynamic treatment regimens

Statistica Sinica, 25(3), 901–920.

By: R. Song, W. Wang, D. Zeng & M. Kosorok

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Reducing disparities in large-scale emergency medical service systems

Journal of the Operational Research Society, 66(7), 1169–1181.

By: H. Toro-Díaz*, M. Mayorga n, L. McLay*, H. Rajagopalan* & C. Saydam*

author keywords: location/allocation in healthcare; hypercube model; tabu search
TL;DR: This work approaches the planning of large-scale EMS systems including fairness considerations using a Tabu Search-based heuristic with an embedded approximation procedure for the queuing submodel, extending the approach in which strategic decisions (location) and operative decisions (dispatching) are combined to balance efficiency and fairness. (via Semantic Scholar)
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2015 journal article

Increasing Prevalence of Diabetes During Pregnancy in South Carolina

Journal of Women’s Health, 24(4), 316–323.

By: C. Lynch*, N. Baker*, J. Korte*, J. Mauldin*, M. Mayorga n & K. Hunt*

MeSH headings : Adult; Black or African American / statistics & numerical data; Birth Certificates; Black People / statistics & numerical data; Diabetes Mellitus, Type 2 / ethnology; Diabetes, Gestational / ethnology; Female; Health Surveys; Hispanic or Latino / statistics & numerical data; Humans; Maternal Age; Pregnancy; Pregnancy in Diabetics / ethnology; Prevalence; Socioeconomic Factors; South Carolina / epidemiology; White People / statistics & numerical data; Young Adult
TL;DR: An increasing prevalence of diabetes during pregnancy is reported, as well as substantial lack of agreement in reporting of diabetes prevalence across administrative databases, which is impacted by screening, diagnostic, and reporting practices across different data sources, aswell as by actual changes in prevalence over time. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

The genomes of two key bumblebee species with primitive eusocial organization

Genome Biology, 16.

By: B. Sadd, S. Barribeau, G. Bloch, D. Graaf, P. Dearden, C. Elsik, J. Gadau, C. Grimmelikhuijzen ...

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Statistical validation of structured population models for Daphnia magna

MATHEMATICAL BIOSCIENCES, 266, 73–84.

By: K. Adoteye n, H. Banks n, K. Cross n, S. Eytcheson n, K. Flores n, G. LeBlanc n, T. Nguyen n, C. Ross n ...

author keywords: Sensitivity analysis; Structured population model; Uncertainty quantification; Density-dependence; Multi-scale data; Daphnia magna
MeSH headings : Animals; Daphnia; Models, Statistical; Population Dynamics
TL;DR: This study develops structured population models that exemplify specific mechanisms and uses multi-scale experimental data in order to test their importance, and shows that fecundity and survival rates are affected by both time-varying density-independent factors and density-dependent factors. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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