Center for Environmental and Health Effects of PFAS

Works Published in 1986

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Displaying all 5 works

Sorted by most recent date added to the index first, which may not be the same as publication date order.

1986 journal article

sn-l, 2-Diacylglycerols mimic the effects of 12-<i>0</i>-tetradecanoylphorbol-13-acetate <i>in vivo</i> by inducing biochemical changes associated with tumor promotion in mouse epidermis

Carcinogenesis, 7(11), 1865–1870.

By: R. Smart*, M. Huang & A. Conney

MeSH headings : Animals; DNA / biosynthesis; Diglycerides / toxicity; Female; Glycerides / toxicity; Mice; Mice, Inbred Strains; Ornithine Decarboxylase / biosynthesis; Protein Kinase C / analysis; Skin / drug effects; Skin / metabolism; Skin Neoplasms / chemically induced; Tetradecanoylphorbol Acetate
TL;DR: Several sn-1,2-diacylglycerols mimic TPA in vivo with respect to their effects on certain biochemical parameters associated with tumor promotion in mouse skin, and these effects are determined by measuring the incorporation of [3H]thymidine into epidermal DNA. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: April 10, 2022

1986 journal article

Effect of ellagic acid and 3-<i>O</i>-decylellagic acid on the formation of benzo[<i>a</i>]pyrene-derived DNA adducts <i>in vivo</i> and on the tumorigenicity of 3-methylcholanthrene in mice

Carcinogenesis, 7(10), 1669–1675.

By: R. Smart*, M. Huang, R. Chang, J. Sayer*, D. Jerina*, A. Wood, A. Conney

MeSH headings : Animals; Antineoplastic Agents / pharmacology; Benzo(a)pyrene / metabolism; Benzopyrans / pharmacology; DNA / metabolism; Dose-Response Relationship, Drug; Ellagic Acid / pharmacology; Female; Lung / metabolism; Methylcholanthrene; Mice; Mice, Inbred BALB C; Skin / metabolism; Skin Neoplasms / chemically induced; Skin Neoplasms / prevention & control; Time Factors; Tritium
TL;DR: Ellagic acid and 3-O-decylellagic acid are not effective in inhibiting [3H]B[a]P DNA adduct formation in mouse skin and lung and that ellagic acid does not inhibit 3-MC-induced skin tumorigenesis in BALB/c or CD-1 mice. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: April 10, 2022

1986 journal article

Disposition of the naturally occurring antimutagenic plant phenol, ellagic acid, and its synthetic derivatives, 3-<i>O</i>-decylellagic acid and 3, 3'-di-<i>O</i>-methylellagic acid in mice

Carcinogenesis, 7(10), 1663–1667.

By: R. Smart*, M. Huang, R. Chang, J. Sayer*, D. Jerina* & A. Conney

MeSH headings : 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide / toxicity; Animals; Antineoplastic Agents / metabolism; Benzopyrans / metabolism; Ellagic Acid / analogs & derivatives; Ellagic Acid / metabolism; Ellagic Acid / pharmacology; Feces / analysis; Female; Injections, Intraperitoneal; Injections, Intravenous; Liver / metabolism; Lung / metabolism; Mice; Mutation
TL;DR: The effect of ellagic acid and some of its more lipophilic derivatives on the mutagenicity of (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenz[a]pyrene was examined in Salmonella typhimurium TA100. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: April 10, 2022

1986 journal article

Effect of dietary ascorbate on covalent binding of benzene to bone marrow and hepatic tissue in vivo

Biochemical Pharmacology, 35(18), 3180–3182.

By: R. Smart* & V. Zannoni*

MeSH headings : Animals; Ascorbic Acid / administration & dosage; Ascorbic Acid / pharmacology; Benzene / metabolism; Bone Marrow / drug effects; Bone Marrow / metabolism; Diet; Guinea Pigs; Liver / drug effects; Liver / metabolism; Male
Sources: Crossref, ORCID
Added: April 9, 2022

1986 conference paper

Parameters Affecting Refuse Methanogenesis and the Solids Composition of Anaerobically Degraded Refuse

Presented at the Ninth Annual Madison Waste Conference, Department of Engineering Professional Development, University of Wisconsin, Madison, WI.

By: M. Barlaz, R. Ham & M. Milke

Event: Ninth Annual Madison Waste Conference at Department of Engineering Professional Development, University of Wisconsin, Madison, WI on September 9-10, 1986

Source: NC State University Libraries
Added: February 27, 2022

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