Works (6)

Updated: July 5th, 2023 21:17

2017 journal article

Evaluation of the Impacts of Epilepsy in Dogs on Their Caregivers

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 53(3), 143–149.

Contributors: J. Nettifee n, K. Munana n & E. Griffith n

MeSH headings : Animals; Anticonvulsants / economics; Anticonvulsants / therapeutic use; Caregivers; Data Collection; Dog Diseases / drug therapy; Dog Diseases / economics; Dogs; Epilepsy / drug therapy; Epilepsy / economics; Epilepsy / veterinary; Humans; Quality of Life; Surveys and Questionnaires
TL;DR: The majority of respondents reported positive scores for overallquality of life, although scores were significantly lower for dogs with poorly controlled epilepsy and medication-related adverse effects, and monthly medication cost was not associated with quality of life score. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

The impact of carboplatin and toceranib phosphate on serum vascular endothelial growth factor (VEGF) and metalloproteinase-9 (MMP-9) levels and survival in canine osteosarcoma

Canadian Journal of Veterinary Research, 81(3), 199–205.

By: T. Gieger, J. Nettifee-Osborne, B. Hallman, C. Johannes, D. Clarke, M. Nolan, L. Williams

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Effect of Chronic Administration of Phenobarbital, or Bromide, on Pharmacokinetics of Levetiracetam in Dogs with Epilepsy

JOURNAL OF VETERINARY INTERNAL MEDICINE, 29(2), 614–619.

By: K. Munana n, J. Nettifee-Osborne n & M. Papich n

Contributors: K. Muñana n, J. Nettifee-Osborne n & M. Papich n

author keywords: Antiepileptic drug; Canine; Drug disposition; Drug interactions; Seizures
MeSH headings : Animals; Anticonvulsants / administration & dosage; Anticonvulsants / pharmacokinetics; Anticonvulsants / therapeutic use; Area Under Curve; Bromides / administration & dosage; Bromides / therapeutic use; Dog Diseases / blood; Dog Diseases / drug therapy; Dog Diseases / metabolism; Dogs; Epilepsy / blood; Epilepsy / drug therapy; Epilepsy / veterinary; Half-Life; Levetiracetam; Phenobarbital / administration & dosage; Phenobarbital / therapeutic use; Piracetam / administration & dosage; Piracetam / analogs & derivatives; Piracetam / pharmacokinetics; Piracetam / therapeutic use
TL;DR: Significant Dosage increases might be indicated when utilizing LEV as add‐on treatment with phenobarbital in dogs when administered concurrently with conventional AEDs. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2013 journal article

Assessment of the prevalence and clinical features of cryptogenic epilepsy in dogs: 45 cases (2003-2011)

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 242(5), 651–657.

By: M. Schwartz n, K. Munana n & J. Nettifee-Osborne n

Contributors: M. Schwartz n, K. Muñana n & J. Nettifee-Osborne n

MeSH headings : Animals; Dog Diseases / diagnosis; Dogs; Epilepsy / diagnosis; Epilepsy / veterinary; Female; Longevity; Male; Retrospective Studies
TL;DR: Cryptogenic epilepsy was diagnosed in a substantial proportion of dogs with an onset of epileptic seizures at ≥ 7 years of age and was considered acceptable in most dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2012 journal article

Evaluation of Levetiracetam as Adjunctive Treatment for Refractory Canine Epilepsy: A Randomized, Placebo-Controlled, Crossover Trial

JOURNAL OF VETERINARY INTERNAL MEDICINE, 26(2), 341–348.

By: K. Munana n, W. Thomas*, K. Inzana*, J. Nettifee-Osborne n, K. McLucas*, N. Olby n, C. Mariani n, P. Early n

Contributors: K. Muñana n, W. Thomas*, K. Inzana*, J. Nettifee-Osborne n, K. McLucas*, N. Olby n, C. Mariani n, P. Early n

author keywords: Clinical pharmacology; CNS disorders; Dog; Epilepsy; Neurology; Seizures
MeSH headings : Animals; Anticonvulsants / administration & dosage; Anticonvulsants / adverse effects; Anticonvulsants / blood; Cross-Over Studies; Dog Diseases / blood; Dog Diseases / drug therapy; Dogs; Double-Blind Method; Epilepsy / blood; Epilepsy / drug therapy; Epilepsy / veterinary; Female; Levetiracetam; Male; Piracetam / administration & dosage; Piracetam / adverse effects; Piracetam / analogs & derivatives; Piracetam / blood; Quality of Life; Seizures / blood; Seizures / drug therapy; Seizures / veterinary; Statistics, Nonparametric
TL;DR: Adjunctive treatment with LEV appears safe in epileptic dogs and effectiveness over placebo was not demonstrated, although the power of the study was limited. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2012 journal article

The pharmacokinetics of midazolam after intravenous, intramuscular, and rectal administration in healthy dogs

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 36(5), 471–477.

By: M. Schwartz n, K. Munana n, J. Nettifee-Osborne n, K. Messenger n & M. Papich n

Contributors: M. Schwartz n, K. Muñana n, J. Nettifee-Osborne n, K. Messenger n & M. Papich n

MeSH headings : Administration, Rectal; Animals; Anticonvulsants / administration & dosage; Anticonvulsants / blood; Anticonvulsants / pharmacokinetics; Chromatography, High Pressure Liquid; Dogs; Female; Injections, Intramuscular / veterinary; Injections, Intravenous / veterinary; Male; Midazolam / administration & dosage; Midazolam / blood; Midazolam / pharmacokinetics
TL;DR: It is suggested that IM midazolam might be useful in treating seizures in dogs when venous access is unavailable, but higher doses may be needed to account for intermediate bioavailability. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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