Works (11)

Updated: July 9th, 2023 21:19

2007 journal article

Potential therapy for mucus hypersecretion in COPD.

404nOtfound, 3, 66–71.

By: J. Park n & K. Adler n

UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Protein kinase C delta regulates airway mucin secretion via phosphorylation of MARCKS protein

AMERICAN JOURNAL OF PATHOLOGY, 171(6), 1822–1830.

By: J. Park n, A. Crews n, W. Lampe n, S. Fang n, J. Park n & K. Adler n

MeSH headings : Acetophenones / pharmacology; Benzopyrans / pharmacology; Bronchi / drug effects; Bronchi / enzymology; Bronchi / metabolism; Bryostatins / pharmacology; Cell Line; Enzyme Activation; Epithelial Cells / drug effects; Epithelial Cells / enzymology; Epithelial Cells / metabolism; Humans; Intracellular Signaling Peptides and Proteins / metabolism; Membrane Proteins / metabolism; Mucins / metabolism; Myristoylated Alanine-Rich C Kinase Substrate; Phosphorylation; Protein Kinase C-delta / antagonists & inhibitors; Protein Kinase C-delta / genetics; Protein Kinase C-delta / physiology; Protein Kinase Inhibitors / pharmacology; Tetradecanoylphorbol Acetate / pharmacology
Source: Web Of Science
Added: August 6, 2018

2007 article

Protein kinase C delta regulates airway mucin secretion via phosphorylation of MARCKS protein.

404nOtfound, Vol. 175, p. A752.

By: J. Park, A. Crews & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2007 article

The (S)?enantiomer of albuterol activates expression of iNOS via activation of NF-kB in primary cultures of normal human bronchial epithelial cells.

404nOtfound, Vol. 175, p. A178.

By: J. Waterman, J. Park, A. Crews & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

(R)-Albuterol elicits antiinflammatory effects in human airway epithelial cells via iNOS

American Journal of Respiratory Cell and Molecular Biology, 34(1), 119–127.

By: B. Chorley, Y. Li, S. Fang, J. Park & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Mechanisms of mucus secretion in the airways.

404nOtfound, 2, 24–29.

By: K. Adler n, S. Fang n, K. Lin n & J. Park n

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Potential therapy for mucus hypersecretion in chronic obstructive pulmonary disease [translated into Chinese].

404nOtfound, 86, 2890–2892.

By: J. Park & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2005 article

Human Neutrophil Elastase provokes mucin secretion by NHBE cells via a Protein Kinase C delta (PKC?)?mediated mechanism.

404nOtfound, Vol. 2, p. A110.

By: J. Park, B. Chorley & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase C delta-mediated mechanism

AMERICAN JOURNAL OF PATHOLOGY, 167(3), 651–661.

By: J. Park n, F. He n, L. Martin n, Y. Li n, B. Chorley n & K. Adler n

MeSH headings : Bronchi / cytology; Bronchi / drug effects; Bronchi / metabolism; Cell Differentiation; Cells, Cultured; Enzyme Activation / drug effects; Epithelial Cells / cytology; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Humans; Isoenzymes / metabolism; Leukocyte Elastase / pharmacology; Mucins / metabolism; Protein Kinase C / metabolism; Protein Kinase C / physiology; Protein Kinase C-delta; Protein Kinase Inhibitors / pharmacology
TL;DR: The results suggest HNE stimulation of mucin release by human airway epithelial cells involves intracellular activation of PKC, specifically the delta isoform. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2004 article

MARCKS protein interaction with the ?secretory module? regulates airway mucin secretion.

American Journal of Respiratory and Critical Care Medicine, Vol. 169, p. A535.

By: J. Park, S. Fang, A. Gruber & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

2003 article

Human neutrophil elastase provokes release of MUC5B mucin from normal bronchial epithelial cells in vitro via a PKC-dependent mechanism.

American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A203.

By: J. Park, F. He, Y. Li, L. Martin & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

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