Jennifer Rae Hutchinson

Works (2)

Updated: July 9th, 2023 19:05

2008 journal article

Genomic Consequences of Background Effects on scalloped Mutant Expressivity in the Wing of Drosophila melanogaster

GENETICS, 181(3), 1065–1076.

By: I. Dworkin n, E. Kennerly n, D. Tack *, J. Hutchinson n, J. Brown n, J. Mahaffey n, G. Gibson n

MeSH headings : Animals; Drosophila Proteins / genetics; Drosophila melanogaster / anatomy & histology; Drosophila melanogaster / cytology; Drosophila melanogaster / genetics; Drosophila melanogaster / metabolism; Epistasis, Genetic; Gene Expression Regulation; Genetic Linkage; Genetic Variation; Genome, Insect / genetics; Genomics; Molecular Sequence Data; Mutation; Nuclear Proteins / genetics; Oligonucleotide Array Sequence Analysis; Transcription Factors / genetics; Transcription, Genetic; Wings, Animal / metabolism
TL;DR: This study demonstrates that phenotypic expressivity of the scallopedE3 (sdE3) mutation of Drosophila melanogaster is background dependent and is the result of at least one major modifier segregating between two standard lab wild-type strains and demonstrates that the epistatic interaction between sdE3 and an optomotor blind mutation is backgrounddependent. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2007 journal article

The appendage role of insect disco genes and possible implications on the evolution of the maggot larval form

DEVELOPMENTAL BIOLOGY, 309(1), 56–69.

By: M. Patel n, L. Farzana n, L. Robertson n, J. Hutchinson n, N. Grubbs n, M. Shepherd n, J. Mahaffey n

author keywords: drosophila; segment identity; zinc finger; appendage; limb; pattern formation
MeSH headings : Animals; Biological Evolution; Body Patterning; DNA-Binding Proteins / metabolism; Drosophila / embryology; Drosophila / growth & development; Drosophila / metabolism; Drosophila Proteins / metabolism; Head / embryology; Head / growth & development; Larva / growth & development; Larva / metabolism; Transcription Factors / metabolism; Tribolium / embryology; Tribolium / growth & development; Tribolium / metabolism
TL;DR: It is proposed that the disco genes always function as appendage factors, but their appendage nature is masked during Drosophila embryogenesis due to the reduction of limb fields in the maggot style Drosophile larva. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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