Emily Elizabeth Wear

Works (10)

Updated: April 5th, 2024 09:02

2021 journal article

Loss of Small-RNA-Directed DNA Methylation in the Plant Cell Cycle Promotes Germline Reprogramming and Somaclonal Variation

CURRENT BIOLOGY, 31(3), 591-+.

MeSH headings : Arabidopsis / genetics; Arabidopsis / metabolism; Cell Cycle; Cytosine; DNA Methylation; DNA, Plant; Gene Expression Regulation, Plant; Germ Cells / metabolism; Histones / genetics; Histones / metabolism; Plants / metabolism; RNA, Small Interfering / genetics
TL;DR: Comparative analysis with methylomes of various tissues and cell types suggests that loss of small-RNA-directed non-CG methylation during DNA replication promotes germline reprogramming and epigenetic variation in plants propagated as clones. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 4, 2020

2020 journal article

Arabidopsis DNA Replication Initiates in Intergenic, AT-Rich Open Chromatin(1)([OPEN])

PLANT PHYSIOLOGY, 183(1), 206–220.

By: E. Wheeler n, A. Brooks n, L. Concia n, D. Vera*, E. Wear n, C. LeBlanc*, U. Ramu*, M. Vaughn ...

MeSH headings : Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Chromatin / metabolism; DNA Replication / genetics; DNA Replication / physiology; DNA, Plant / metabolism; DNA, Plant / physiology; Replication Origin / genetics; Replication Origin / physiology
TL;DR: A new functional assay to label and map very early replicating loci that must, by definition, include at least a subset of replication origins, and indicates that IRs are associated with accessible chromatin. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 15, 2020

2020 journal article

Comparing DNA replication programs reveals large timing shifts at centromeres of endocycling cells in maize roots

PLOS GENETICS, 16(10).

By: E. Wear n, J. Song, G. Zynda, L. Mickelson-Young n, C. LeBlanc*, T. Lee n, D. Deppong n, G. Allen n ...

MeSH headings : Cell Nucleus / drug effects; Cell Nucleus / genetics; Centromere / drug effects; Centromere / genetics; DNA Replication / drug effects; DNA Replication / genetics; DNA Replication Timing / drug effects; DNA Replication Timing / genetics; DNA, Plant / drug effects; DNA, Plant / genetics; Deoxyuridine / analogs & derivatives; Deoxyuridine / pharmacology; Endocytosis / drug effects; Meristem / drug effects; Meristem / genetics; Mitosis / drug effects; Mitosis / genetics; Nucleosomes / drug effects; Plant Roots / drug effects; Plant Roots / genetics; Plant Roots / growth & development; S Phase / genetics; Zea mays / genetics; Zea mays / growth & development
Sources: Web Of Science, NC State University Libraries
Added: November 9, 2020

2018 article

Chromatin structure profile data from DNS-seq: Differential nuclease sensitivity mapping of four reference tissues of B73 maize (Zea mays L)

Turpin, Z. M., Vera, D. L., Savadel, S. D., Lung, P.-Y., Wear, E. E., Mickelson-Young, L., … Bass, H. W. (2018, October). DATA IN BRIEF, Vol. 20, pp. 358–363.

By: Z. Turpin*, D. Vera*, S. Savadel*, P. Lung*, E. Wear n, L. Mickelson-Young n, W. Thompson n, L. Hanley-Bowdoin n ...

TL;DR: Data from Next-Generation Sequencing of differential micrococcal nuclease digestions of formaldehyde-crosslinked chromatin in selected tissues of maize (Zea mays) inbred line B73 are presented. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: December 3, 2018

2018 journal article

Genome-Wide Analysis of the Arabidopsis Replication Timing Program

PLANT PHYSIOLOGY, 176(3), 2166–2185.

By: L. Concia n, A. Brooks n, E. Wheeler n, G. Zynda, E. Wear n, C. LeBlanc*, J. Song, T. Lee n ...

MeSH headings : Arabidopsis / genetics; Chromatin / genetics; Chromatin / metabolism; Chromosomes, Plant; DNA Replication Timing; DNA Transposable Elements; Flow Cytometry; Genome, Plant; Genome-Wide Association Study; S Phase / genetics; Sequence Analysis, DNA / methods
TL;DR: The thymidine analog, 5-ethynyl-2′-deoxyuridine, is used in combination with flow sorting and Repli-Seq to describe the genome-wide replication timing program for Arabidopsis (Arabidopsis thaliana) Col-0 suspension cells, and genomic regions that replicate predominantly during early, mid, and late S phase are identified. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Genomic Analysis of the DNA Replication Timing Program during Mitotic S Phase in Maize (Zea mays) Root Tips

PLANT CELL, 29(9), 2126–2149.

By: E. Wear n, J. Song, G. Zynda, C. LeBlanc*, T. Lee n, L. Mickelson-Young n, L. Concia n, P. Mulvaney n ...

MeSH headings : Base Sequence; Chromosomes, Plant / genetics; DNA Replication Timing / genetics; DNA Transposable Elements / genetics; Genes, Plant; Genomics; Meristem / cytology; Meristem / genetics; Mitosis / genetics; Models, Genetic; S Phase / genetics; Tandem Repeat Sequences / genetics; Time Factors; Transcription, Genetic; Zea mays / cytology; Zea mays / genetics
TL;DR: A novel adaptation of the “Repli-seq” assay for use in intact root tips of maize (Zea mays) that includes several different cell lineages and present whole-genome replication timing profiles from cells in early, mid, and late S phase of the mitotic cell cycle is reported. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2017 journal article

Repliscan: a tool for classifying replication timing regions

BMC BIOINFORMATICS, 18, 1–14.

By: G. Zynda, J. Song, L. Concia n, E. Wear n, L. Hanley-Bowdoin n, W. Thompson n, M. Vaughn

author keywords: DNA replication; Repli-seq; Classification
MeSH headings : DNA Replication Timing; Genome; Genome Size; High-Throughput Nucleotide Sequencing / methods; Sequence Analysis, DNA / methods; Software
TL;DR: To accurately detect and classify regions of replication across the genome, Repliscan is presented, which robustly normalizes, automatically removes outlying and uninformative data points, and classifies Repli-seq signals into discrete combinations of replication signatures. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2016 journal article

A flow cytometric method for estimating S-phase duration in plants

JOURNAL OF EXPERIMENTAL BOTANY, 67(21), 6077–6087.

By: L. Mickelson-Young n, E. Wear n, P. Mulvaney n, T. Lee n, E. Szymanski n, G. Allen n, L. Hanley-Bowdoin n, W. Thompson n

author keywords: Arabidopsis; barley; EdU; flow cytometry; maize; replication timing; rice; S-phase duration; wheat
MeSH headings : Arabidopsis / cytology; Arabidopsis / growth & development; DNA, Plant / metabolism; Deoxyuridine / analogs & derivatives; Deoxyuridine / metabolism; Flow Cytometry / methods; G1 Phase / physiology; G2 Phase / physiology; Hordeum / cytology; Hordeum / growth & development; Meristem / cytology; Meristem / growth & development; Oryza / cytology; Oryza / growth & development; S Phase / physiology; Triticum / cytology; Triticum / growth & development; Zea mays / cytology; Zea mays / growth & development
TL;DR: This work estimated S-phase duration for several plant species by following EdU-labeled nuclei from G1 to G2 using bivariate flow cytometry, finding that S- phase duration is relatively consistent over a range of genome sizes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

Defining multiple, distinct, and shared spatiotemporal patterns of DNA replication and endoreduplication from 3D image analysis of developing maize (Zea mays L.) root tip nuclei

PLANT MOLECULAR BIOLOGY, 89(4-5), 339–351.

By: H. Bass*, G. Hoffman*, T. Lee n, E. Wear n, S. Joseph*, G. Allen n, L. Hanley-Bowdoin n, W. Thompson n

author keywords: Cell cycle; DNA synthesis; Grass
MeSH headings : Cell Nucleus / genetics; Cell Nucleus / metabolism; DNA Replication / genetics; DNA Replication Timing / genetics; DNA, Plant / biosynthesis; DNA, Plant / genetics; Endoreduplication / genetics; Genes, Plant; Imaging, Three-Dimensional; Meristem / genetics; Meristem / growth & development; Meristem / metabolism; Models, Biological; S Phase / genetics; Zea mays / genetics; Zea mays / growth & development; Zea mays / metabolism
TL;DR: 3D quantitative analysis of DNA replication and endoreduplication in nuclei from pulse-labeled developing maize root tips revealed that maize euchromatin exists as an intermingled mixture of two components distinguished by their condensation state and replication timing. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2009 journal article

Invasion of a West Everglades wetland by Melaleuca quinquenervia countered by classical biological control

BIOLOGICAL CONTROL, 48(1), 73–78.

By: P. Tipping*, M. Martin*, K. Nimmo*, R. Pierce*, M. Smart*, E. White n, P. Madeira*, T. Center*

author keywords: Weed biological control; Melaleuca; Florida Everglades; Community level impacts
TL;DR: This is the first study with controls that quantifies the population level regulation ofmelaleuca by introduced biological control agents and corroborates other correlative studies that documented significant changes in melaleuca communities after the introduction and establishment of biological controlagents. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.