Morgan Marie Barnes
College of Sciences
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Works (4)
Updated: November 27th, 2024 11:02
2024 article
Quantitative sampling by IR-MALDESI is not susceptible to tissue heterogeneity in a multi-organ model
Joignant, A. N., Hector, E. C., Barnes, M. M., Kullman, S. W., & Muddiman, D. C. (2024, November 13). ANALYTICAL AND BIOANALYTICAL CHEMISTRY.
author keywords: IR-MALDESI; Mass spectrometry imaging; Quantitative; Zebrafish
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: Web Of Science
Added: November 25, 2024
2023 article
Comparative analysis of sucrose-embedding for whole-body zebrafish MSI by IR-MALDESI
Wang, M. F., Ritter, M. M., Kullman, S. W., & Muddiman, D. C. (2023, August 29). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 8.
author keywords: IR-MALDESI; Mass spectrometry imaging; Sucrose; PFA; Zebrafish
TL;DR:
Danio rerio, or zebrafish, are model organisms for various disease states and can be imaged as a multi-organ sample to analyze morphological and metabolomic preservation as a result of sample preparation to compare sucrose-embedding with paraformaldehyde fixation against conventional fresh-frozen sample preparation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 25, 2023
2023 article
Maximized Spatial Information and Minimized Acquisition Time of Top-Hat IR-MALDESI-MSI of Zebrafish Using Nested Regions of Interest (nROIs)
Joignant, A. N., Ritter, M. M., Knizner, K. T., Garrard, K. P., Kullman, S. W., & Muddiman, D. C. (2023, August 1). JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, Vol. 8.
author keywords: IR-MALDESI; mass spectrometry imaging; spatialresolution; nested region of interest; zebrafish
TL;DR:
The nROI method was characterized on mouse liver and applied to top-hat MSI of zebrafish using a novel optical train, which resulted in a significant improvement in both acquisition time and spatial detail of the zebra fish.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 21, 2023
2021 journal article
Vitamin D deficiency promotes accumulation of bioactive lipids and increased endocannabinoid tone in zebrafish
JOURNAL OF LIPID RESEARCH, 62.
author keywords: MS; metabolomics; lipidomics; lipids; nutrition; endocannabinoid biosynthesis; MSI; IR-MALDESI; anandamide
MeSH headings : Animals; Endocannabinoids / metabolism; Lipid Metabolism; Lipids / chemistry; Vitamin D Deficiency / metabolism; Zebrafish
TL;DR:
Investigation of putative linkages between vitamin D deficiency and metabolic disruption of bioactive lipids by MS imaging and expression of genes involved in EC biosynthesis, metabolism, and receptor signaling in adipose tissue and liver suggest that VDD may promote accumulation of bio active lipids and increased EC tone in zebrafish.
(via Semantic Scholar)
open access via www.jlr.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 19, 2021
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