Works Published in 2015
Displaying works 1 - 20 of 195 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2015 journal article
Healthy n-6/n-3 fatty acid composition from five European game meat species remains after cooking
BMC Research Notes, 8(1).
bmcresnotes.biomedcentral.com (publisher PDF)
Source: ORCID
Added: January 28, 2024
2015 journal article
Loss of Hif-2α Rescues the Hif-1α Deletion Phenotype of Neonatal Respiratory Distress In Mice.
PloS One.
MeSH headings : Animals; Animals, Newborn; Basic Helix-Loop-Helix Transcription Factors / deficiency; Basic Helix-Loop-Helix Transcription Factors / genetics; Gene Deletion; Gene Regulatory Networks; Genotype; Hypoxia-Inducible Factor 1, alpha Subunit / deficiency; Hypoxia-Inducible Factor 1, alpha Subunit / genetics; Lung / metabolism; Lung / pathology; Mice; Phenotype; Respiratory Distress Syndrome, Newborn / genetics; Respiratory Distress Syndrome, Newborn / metabolism; Respiratory Distress Syndrome, Newborn / pathology; Signal Transduction; Survival Analysis; Transcription, Genetic
TL;DR:
Investigation of the independent role of Hif-2α in lung epithelium and its ability to alter H IF-1α-mediated lung maturation suggests that modulation of hormone-mediated, NF-κB, C/EBPα, and c-MYC signaling are central to HIF-mediated changes in lung development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: August 2, 2023
2015 journal article
Hypoxia Inducible Factors Modulate Mitochondrial Oxygen Consumption and Transcriptional Regulation of Nuclear-Encoded Electron Transport Chain Genes.
Biochemistry, 6.
MeSH headings : Animals; Cell Hypoxia; Cells, Cultured; Clone Cells; Electron Transport Complex IV / antagonists & inhibitors; Electron Transport Complex IV / genetics; Electron Transport Complex IV / metabolism; Embryo, Mammalian / cytology; Embryo, Mammalian / metabolism; Enzyme Induction / drug effects; Enzyme Inhibitors / pharmacology; Gene Expression Profiling; Hypoxia-Inducible Factor 1, alpha Subunit / genetics; Hypoxia-Inducible Factor 1, alpha Subunit / metabolism; Mice; Mice, Transgenic; Mitochondria / drug effects; Mitochondria / enzymology; Mitochondria / metabolism; Oxidative Phosphorylation / drug effects; Oxygen Consumption / drug effects; RNA, Messenger / metabolism; Recombinant Proteins / metabolism; Transcriptional Activation / drug effects
TL;DR:
It is proposed that adaptation to hypoxic stress of CcO as the main cellular oxygen consumer is mediated by induction of hypoxia-sensitive tissue-specific isoforms, and it is suggested that HIF1 plays a central role in maintaining homeostasis in cellular respiration duringhypoxic stress via regulation of C c oxidase activity.
(via Semantic Scholar)
Source: ORCID
Added: August 2, 2023
2015 journal article
Angiotensin II-induced hypertensive renal inflammation is mediated through HMGB1-TLR4 signaling in rat tubulo-epithelial cells.
Experimental Cell Research, 7.
MeSH headings : Angiotensin II; Animals; Antihypertensive Agents / pharmacology; Cell Line; Epithelial Cells / immunology; Epithelial Cells / metabolism; HMGB1 Protein / metabolism; Hypertension / chemically induced; Hypertension / complications; Hypertension / metabolism; Kidney Failure, Chronic / etiology; Kidney Failure, Chronic / immunology; Kidney Failure, Chronic / metabolism; Kidney Tubules / pathology; Losartan / pharmacology; NF-kappa B / metabolism; Rats; Signal Transduction; Toll-Like Receptor 4 / metabolism
TL;DR:
A key role for HMGB1-TLR4 signaling is indicated in AngII-mediated inflammation in the renal epithelial cells, suggesting this pathway as a potential therapeutic target for hypertensive renal dysfunctions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: August 2, 2023
2015 journal article
In vivo tracking and immunological properties of pulsed porcine monocyte-derived dendritic cells
Molecular Immunology, 63(2), 343–354.
MeSH headings : Animals; Cell Shape; Cell Survival; Cell Tracking / methods; Dendritic Cells / cytology; Dendritic Cells / immunology; Dextrans / metabolism; Enzyme-Linked Immunospot Assay; Humans; Immunization; Immunohistochemistry; Interferon-gamma / metabolism; Lymph Nodes / pathology; Magnetic Resonance Imaging; Magnetite Nanoparticles; Monocytes / cytology; Phenotype; Staining and Labeling; Sus scrofa
TL;DR:
The results showed that after one single subcutaneous dose of pulsed MoDCs, pigs were able to elicit specific local and systemic immune responses and the dynamic imaging of MRI-based DC tracking was shown using SPIO particles.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 1, 2023
2015 journal article
Demonstration of the Cell Clonality in Canine Hematopoietic Tumors by X-chromosome Inactivation Pattern Analysis
Veterinary Pathology, 52(1), 61–69.
Contributors: H. Mochizuki* , Y. Goto-Koshino *, M. Takahashi*, Y. Fujino*, K. Ohno * & H. Tsujimoto *
MeSH headings : Animals; Biomarkers, Tumor / metabolism; Clone Cells; Dogs; Female; Hematologic Neoplasms / genetics; Hematologic Neoplasms / pathology; Hematologic Neoplasms / veterinary; Heterozygote; Humans; Leukemia / genetics; Leukemia / pathology; Leukemia / veterinary; Lymphoma / genetics; Lymphoma / pathology; Lymphoma / veterinary; Male; Polymorphism, Genetic / genetics; X Chromosome Inactivation
TL;DR:
XCIP analysis was successfully employed to demonstrate the cell clonality of canine hematopoietic tumors in this study and will be applicable to evaluate theClonality in various proliferative disorders in dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: May 23, 2023
2015 journal article
Construction of a multicolor GeneScan analytical system to detect clonal rearrangements of immunoglobulin and T cell receptor genes in canine lymphoid tumors
Veterinary Immunology and Immunopathology, 165(1-2), 81–87.
Contributors: Y. Goto-Koshino *, H. Mochizuki* , M. Sato*, K. Nakashima *, S. Hiyoshi*, A. Fujiwara-Igarashi *, S. Maeda *, K. Nakamura *
MeSH headings : Animals; Dog Diseases / genetics; Dog Diseases / immunology; Dogs / genetics; Gene Rearrangement / genetics; Genes, T-Cell Receptor gamma / genetics; Immunoglobulin Heavy Chains / genetics; Immunoglobulins / genetics; Lymphoma / genetics; Lymphoma / immunology; Lymphoma / veterinary; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Receptors, Antigen, T-Cell / genetics
TL;DR:
A multicolor GeneScan analytical system to improve the sensitivity and resolution of the clonality analysis of antigen receptor gene rearrangements in dogs and may prove to be helpful for the diagnosis of lymphoid tumors in dogs.
(via Semantic Scholar)
Source: ORCID
Added: May 23, 2023
2015 journal article
Environmental influences on the seasonal distribution of Vibrio parahaemolyticus in the Pacific Northwest of the USA.
FEMS Microbiology Ecology.
author keywords: pathogens; Vibrio; HABS; microbial ecology
MeSH headings : Animals; Diatoms / isolation & purification; Diatoms / microbiology; Dinoflagellida / chemistry; Dinoflagellida / microbiology; Harmful Algal Bloom; Humans; Kainic Acid / analogs & derivatives; Kainic Acid / analysis; Ostreidae / microbiology; Phytoplankton / isolation & purification; Phytoplankton / pathogenicity; Salinity; Seasons; Seawater / chemistry; Seawater / microbiology; Silicates / analysis; Silicates / chemistry; Temperature; Vibrio Infections / epidemiology; Vibrio parahaemolyticus / isolation & purification; Vibrio parahaemolyticus / pathogenicity; Washington / epidemiology; Water Microbiology
TL;DR:
Results from this study differ from those in other regions corroborating previous findings that environmental factors that trigger vibrio and HAB events may differ depending on geographic locations, and caution should be used when applying results from one region to another.
(via Semantic Scholar)
Source: ORCID
Added: December 30, 2022
2015 journal article
Surveillance for Waterborne Disease Outbreaks Associated with Drinking Water - United States, 2011-2012.
MMWR. Morbidity and Mortality Weekly Report.
MeSH headings : Acute Disease; Disease Outbreaks / statistics & numerical data; Drinking Water / microbiology; Drinking Water / parasitology; Drinking Water / virology; Gastrointestinal Diseases / epidemiology; Gastrointestinal Diseases / microbiology; Gastrointestinal Diseases / parasitology; Gastrointestinal Diseases / virology; Humans; Legionella / isolation & purification; Legionellosis / epidemiology; Population Surveillance; Respiratory Tract Diseases / epidemiology; Respiratory Tract Diseases / microbiology; United States / epidemiology; Water Microbiology; Water Pollution / adverse effects
Source: ORCID
Added: December 30, 2022
2015 journal article
Outbreaks Associated With Environmental and Undetermined Water Exposures - United States, 2011-2012.
MMWR. Morbidity and Mortality Weekly Report.
MeSH headings : Acute Disease; Disease Outbreaks / statistics & numerical data; Drinking Water / microbiology; Environmental Exposure / adverse effects; Fresh Water / parasitology; Gastrointestinal Diseases / epidemiology; Gastrointestinal Diseases / parasitology; Giardia / isolation & purification; Humans; Legionella / isolation & purification; Respiratory Tract Diseases / epidemiology; Respiratory Tract Diseases / microbiology; United States / epidemiology; Water Microbiology; Water Pollution
TL;DR:
Exposures to contaminated water can lead to waterborne disease outbreaks associated with various sources, including many that are classified and reported separately as drinking water or recreational water.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: December 30, 2022
2015 journal article
Epidemiology and Ecology of Opportunistic Premise Plumbing Pathogens: Legionella pneumophila, Mycobacterium avium, and Pseudomonas aeruginosa.
Environmental Health Perspectives.
MeSH headings : Housing; Humans; Legionella pneumophila / physiology; Legionnaires' Disease / epidemiology; Legionnaires' Disease / microbiology; Legionnaires' Disease / prevention & control; Mycobacterium avium / physiology; Pseudomonas Infections / epidemiology; Pseudomonas Infections / microbiology; Pseudomonas Infections / prevention & control; Pseudomonas aeruginosa / physiology; Tuberculosis / epidemiology; Tuberculosis / microbiology; Tuberculosis / prevention & control; Water Supply
TL;DR:
A review of the epidemiology and ecology of these three bacterial OPPPs, specifically to identify common and unique features, and the need to develop means to reduce OPPP exposure is presented.
(via Semantic Scholar)
Source: ORCID
Added: December 30, 2022
2015 journal article
A Prospective Study of Marine Phytoplankton and Reported Illness Among Recreational Beachgoers in Puerto Rico, 2009.
Environmental Health Perspectives.
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Bathing Beaches / statistics & numerical data; Child; Child, Preschool; Cohort Studies; Cyanobacteria / isolation & purification; Environmental Exposure / statistics & numerical data; Exanthema / microbiology; Eye Diseases / microbiology; Female; Humans; Infant; Male; Middle Aged; Phytoplankton / isolation & purification; Prospective Studies; Puerto Rico; Recreation; Respiratory Tract Diseases / microbiology; Seawater / adverse effects; Seawater / microbiology
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: December 30, 2022
2015 journal article
The Risk of Cyanobacterial Toxins in Dialysate: What Do We Know?
Seminars in Dialysis.
MeSH headings : Bacterial Toxins / analysis; Bacterial Toxins / poisoning; Cyanobacteria Toxins; Dialysis Solutions / chemistry; Humans; Marine Toxins / analysis; Marine Toxins / poisoning; Microcystins / analysis; Microcystins / poisoning; Poisoning / prevention & control; Renal Dialysis
TL;DR:
Until these issues are adequately addressed, hemodialysis centers should be aware of the potential for cyanotoxins to be present in their potable water supply, particularly when it comes from surface water sources prone to cyanobacterial blooms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: December 30, 2022
2015 journal article
Outbreaks of Illness Associated with Recreational Water--United States, 2011-2012.
MMWR. Morbidity and Mortality Weekly Report. https://europepmc.org/articles/PMC4584744
Source: ORCID
Added: December 30, 2022
2015 journal article
Extreme Precipitation and Emergency Room Visits for Gastrointestinal Illness in Areas with and without Combined Sewer Systems: An Analysis of Massachusetts Data, 2003-2007.
Environmental Health Perspectives.
MeSH headings : Drinking Water / adverse effects; Emergency Service, Hospital / statistics & numerical data; Gastrointestinal Diseases / epidemiology; Gastrointestinal Diseases / etiology; Humans; Massachusetts / epidemiology; Rain; Recreation; Wastewater / toxicity; Water Supply
TL;DR:
The findings suggest an increased risk for GI illness among consumers whose drinking water source may be impacted by CSOs after extreme precipitation after heavy rainfall.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: December 30, 2022
2015 journal article
Self-Reported Acute Health Effects and Exposure to Companion Animals
Zoonoses and Public Health.
author keywords: Pets; acute disease; signs and symptoms; zoonotic diseases; allergy
MeSH headings : Adolescent; Adult; Animals; Child; Child, Preschool; Female; Gastrointestinal Diseases / etiology; Humans; Hypersensitivity; Male; Middle Aged; Odds Ratio; Pets; Respiratory Tract Diseases / etiology; Skin Diseases / etiology; Young Adult
TL;DR:
Results indicate that contact with animals, especially unfamiliar animals, was significantly associated with GI, respiratory and skin/eye symptoms, which could be attributable to zoonotic infections and allergic reactions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: December 30, 2022
2015 journal article
Landscape risk factors for Lyme disease in the eastern broadleaf forest province of the Hudson River valley and the effect of explanatory data classification resolution
author keywords: Land use; Landcover; Lyme disease; Landscape design; Negative binomial regression; New York
MeSH headings : Agriculture; Animals; Borrelia burgdorferi / isolation & purification; Ecosystem; Environmental Monitoring; Forests; Humans; Ixodes / microbiology; Lyme Disease / epidemiology; Models, Statistical; New York / epidemiology; Risk Factors; Rivers; Statistics, Nonparametric
TL;DR:
Results indicate that regional landscape models for Lyme disease rate are robust to NLCD landcover classification resolution.
(via Semantic Scholar)
Source: ORCID
Added: December 30, 2022
2015 journal article
Environmental risk factors associated with Helicobacter pylori seroprevalence in the United States: a cross-sectional analysis of NHANES data
Epidemiology and Infection.
author keywords: Environmental exposure; Helicobacter pylori; nutrition surveys; seroepidemiological studies; seroprevalence
MeSH headings : Adolescent; Adult; Age Factors; Child; Child, Preschool; Cross-Sectional Studies; Female; Health Status; Helicobacter Infections / epidemiology; Helicobacter Infections / ethnology; Helicobacter pylori; Humans; Male; Middle Aged; Nutrition Surveys; Occupations / statistics & numerical data; Seroepidemiologic Studies; Socioeconomic Factors; Soil Microbiology; United States / epidemiology; Water Wells / microbiology; Young Adult
TL;DR:
A disproportionate burden of infection is associated with poor health and crowded living conditions, but risks vary by age and race/ethnicity, and interventions to reduce the burden of infections in the United States are needed.
(via Semantic Scholar)
Source: ORCID
Added: December 30, 2022
2015 journal article
One Health and Cyanobacteria in Freshwater Systems: Animal Illnesses and Deaths Are Sentinel Events for Human Health Risks
MeSH headings : Animal Diseases / epidemiology; Animals; Cyanobacteria; Environmental Monitoring; Fresh Water / microbiology; Harmful Algal Bloom; Humans; Public Health; Risk Assessment / methods
TL;DR:
It is found that illnesses or deaths among livestock, dogs and fish are all potentially useful as sentinel events for the presence of harmful cyanobacteria that may impact human health.
(via Semantic Scholar)
Source: ORCID
Added: December 30, 2022
2015 journal article
Flooding and Clostridium difficile Infection: A Case-Crossover Analysis
International Journal of Environmental Research and Public Health.
author keywords: epidemiology; Clostridium difficile; community-associated; flooding; case-crossover
MeSH headings : Adult; Aged; Anti-Bacterial Agents / therapeutic use; Antibiotics, Antitubercular; Climate Change; Clostridioides difficile / isolation & purification; Clostridium Infections / drug therapy; Clostridium Infections / epidemiology; Cross-Over Studies; Female; Floods; Humans; Logistic Models; Male; Massachusetts / epidemiology; Middle Aged; Odds Ratio; Sex Distribution; Young Adult
TL;DR:
Although the authors were unable to differentiate community-associated versus nosocomial infections, a potential increase in C. difficile infections should be considered as more flooding is projected due to climate change.
(via Semantic Scholar)
Source: ORCID
Added: December 30, 2022
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