Works Published in 2015
Displaying works 41 - 60 of 259 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2015 journal article
Prediction of human population responses to toxic compounds by a collaborative competition
Nature Biotechnology, 33(9), 933–940.
MeSH headings : Computer Simulation; Dose-Response Relationship, Drug; Genetic Predisposition to Disease / genetics; Genetics, Population; Hazardous Substances / toxicity; High-Throughput Screening Assays / methods; Humans; Incidence; Lymphocytes / cytology; Lymphocytes / drug effects; Lymphocytes / physiology; Models, Genetic; Risk Assessment / methods; Toxicity Tests / methods
TL;DR:
The results from a community-based DREAM challenge to predict toxicities of environmental compounds with potential adverse health effects for human populations highlight the possibility of predicting health risks associated with unknown compounds, although risk estimation accuracy remains suboptimal.
(via Semantic Scholar)
www.nature.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: Crossref
Added: February 24, 2020
2015 journal article
Erratum: Prediction of human population responses to toxic compounds by a collaborative competition
Nature Biotechnology, 33(10), 1109–1109.
TL;DR:
The authors have added 12 additional authors to the list of “Other participants in the NIEHS-NCATS-UNC DREAM Toxicogenetics Collaboration,” including Alok Jaiswal, Antti Poso, Himanshu Chheda, Ismeet Kaur, Jing Tang, John-Patrick Mpindi, Krister Wennerberg, Natalio Krasnogor, Samuel Kaski and Tero Aittokallio.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2015 journal article
Pharmacometabolomic Assessments of Atenolol and Hydrochlorothiazide Treatment Reveal Novel Drug Response Phenotypes
CPT: Pharmacometrics & Systems Pharmacology, 4(11), 669–679.
TL;DR:
The metabolites identified herein may serve as biomarkers for improving treatment decisions and elucidating mechanisms driving HTN treatment responses as part of a quantitative systems pharmacology approach.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Crossref
Added: February 24, 2020
2015 journal article
Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder
The American Journal of Human Genetics, 96(2), 283–294.
MeSH headings : Bipolar Disorder / genetics; Depressive Disorder, Major / genetics; Genetic Testing / methods; Genetics, Medical / methods; Humans; Linear Models; Mental Disorders / genetics; Multifactorial Inheritance / genetics; Multivariate Analysis; Polymorphism, Single Nucleotide / genetics; Risk Assessment / methods; Schizophrenia / genetics
TL;DR:
The multivariate approach significantly increases the prediction accuracy for schizophrenia, bipolar disorder, and major depressive disorder in the discovery as well as in independent validation datasets and is a flexible and powerful tool to maximize prediction accuracy.
(via Semantic Scholar)
Source: Crossref
Added: February 24, 2020
2015 journal article
Selective Internal Radiation Therapy: Quantifying Distal Penetration and Distribution of Resin and Glass Microspheres in a Surrogate Arterial Model
Journal of Vascular and Interventional Radiology, 26(6), 897–904.e2.
MeSH headings : Animals; Embolization, Therapeutic / methods; Glass / chemistry; Hemodynamics; Hepatic Artery / pathology; Hepatic Artery / physiopathology; Humans; Injections, Intra-Arterial; Liver Circulation; Liver Neoplasms / blood supply; Liver Neoplasms / pathology; Liver Neoplasms / radiotherapy; Microspheres; Models, Anatomic; Particle Size; Radiopharmaceuticals / administration & dosage; Resins, Synthetic / chemistry; Technetium Tc 99m Aggregated Albumin / administration & dosage
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: February 24, 2020
2015 journal article
Influence of Drawdown Period on Overflow Volume and Pollutant Treatment for Detention-Based Stormwater Control Measures in Raleigh, North Carolina
Journal of Sustainable Water in the Built Environment, 1(2), 05015001.
author keywords: Hydraulic retention time; Stormwater wetlands; Overflow volume; North Carolina
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: Crossref
Added: February 24, 2020
2015 journal article
Comparison of Runoff Quality and Quantity from a Commercial Low-Impact and Conventional Development in Raleigh, North Carolina
Journal of Environmental Engineering, 141(2), 05014005.
author keywords: Low impact development; Green infrastructure; Grey infrastructure; Stormwater management; Runoff; Nutrients; Infiltration; North Carolina; Hydrology; Peak flow
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science; OpenAlex)
Source: Crossref
Added: February 24, 2020
2015 journal article
Perspectives of wildlife conservation professionals on intensive deer management
Wildlife Society Bulletin, 39(4), 751–756.
author keywords: deer management; North American Model; Odocoileus virginianus; privatization; Texas; white-tailed deer
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Crossref
Added: February 21, 2020
2015 chapter
Quantitative SNP Genotyping of Polyploids with MassARRAY and Other Platforms
In Methods in Molecular Biology (Vol. 1245, pp. 215–241).
Contributors: M. Mollinari* & O. Serang*
author keywords: Polyploids; MassARRAY; SNP; Quantitative genotyping
MeSH headings : Alleles; Crosses, Genetic; Genetic Loci / genetics; Genotype; Genotyping Techniques / methods; Polymorphism, Single Nucleotide / genetics; Polyploidy; Saccharum / genetics; Software; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Statistics as Topic
TL;DR:
The experimental methods for collecting relative allele intensities and the practical concerns for inferring genotypes using Bayesian inference via the software package SuperMASSA are described and demonstrated.
(via Semantic Scholar)
Source: ORCID
Added: February 21, 2020
2015 journal article
Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis
Nature Communications, 6(1).
MeSH headings : Adolescent; Adult; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral / genetics; Child; Cystic Fibrosis / genetics; Cystic Fibrosis / metabolism; Cystic Fibrosis / pathology; Female; Genome-Wide Association Study; Humans; Lung / metabolism; Lung / pathology; Male; Middle Aged; Mucin-4 / genetics; Mucins / genetics; Severity of Illness Index; Transcription Factors / genetics; Young Adult
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Crossref
Added: February 5, 2020
2015 journal article
Identification of Novel Gene Targets and Putative Regulators of Arsenic-Associated DNA Methylation in Human Urothelial Cells and Bladder Cancer
Chemical Research in Toxicology, 28(6), 1144–1155.
MeSH headings : Adult; Aged; Arsenic / metabolism; Arsenic / toxicity; Cell Transformation, Neoplastic / chemically induced; DNA Methylation / drug effects; DNA Methylation / genetics; Female; Humans; Middle Aged; Urinary Bladder Neoplasms / chemically induced; Urinary Bladder Neoplasms / genetics; Urinary Bladder Neoplasms / pathology; Urothelium / cytology; Urothelium / drug effects; Young Adult
TL;DR:
Both the arsenic- and cancer-associated genes are enriched for the binding sites of common transcription factors known to play roles in carcinogenesis, demonstrating a novel potential mechanistic link between iAs exposure and bladder cancer.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
6. Clean Water and Sanitation
(Web of Science)
Source: Crossref
Added: February 5, 2020
2015 journal article
A robust method for estimating optimal treatment regimes
Biometrics, 71, 271–273.
MeSH headings : Breast Neoplasms / epidemiology; Breast Neoplasms / therapy; Clinical Trials as Topic / methods; Decision Support Systems, Clinical; Female; Humans; Models, Statistical; Outcome Assessment, Health Care / methods
Sources: Crossref, NC State University Libraries
Added: January 27, 2020
2015 chapter
Chapter 9: Value search estimators for optimal dynamic treatment regimes
In Adaptive Treatment Strategies in Practice (pp. 135–155).
Sources: Crossref, NC State University Libraries
Added: January 22, 2020
2015 journal article
Special issue on Bayesian nonparametrics
Journal of Statistical Planning and Inference, 166, 1.
Source: Crossref
Added: January 19, 2020
2015 journal article
Properties of Estimators in Exponential Family Settings with Observationbased Stopping Rules
Journal of Biometrics & Biostatistics, 07(01).
TL;DR:
It is established that the ordinary sample average is a very sensible choice, contrary to commonly encountered statements, in the context of outcomes following an exponential family distribution and with a stochastic stopping rule that includes a deterministic rule and completely random sample size as special cases.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 19, 2020
2015 journal article
On tests of activation map dimensionality for fMRI-based studies of learning
Frontiers in Neuroscience, 9.
author keywords: canonical variates analysis; cognitive learning; BOLD fMRI; statistical parametric mapping; interaction test
TL;DR:
The development of the framework, a large scale simulation study, and the subsequent application to a study of motor learning in healthy adults found that the study of linear dimensionality is able to capture learning effects.
(via Semantic Scholar)
Source: ORCID
Added: January 15, 2020
2015 journal article
Movement prediction using accelerometers in a human population
Biometrics, 72(2), 513–524.
author keywords: Accelerometer; Activity type; Movelets; Prediction
MeSH headings : Accelerometry / statistics & numerical data; Activities of Daily Living; Forecasting; Humans; Movement / physiology; Posture; Supervised Machine Learning
TL;DR:
Analysis of statistical methods for predicting the types of human activity at sub‐second resolution using triaxial accelerometry data indicates that prediction of activity types for data collected during natural activities of daily living may actually be possible.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, NC State University Libraries
Added: January 15, 2020
2015 journal article
On the sample covariance matrix estimator of reduced effective rank population matrices, with applications to fPCA
Bernoulli, 21(2), 1200–1230.
author keywords: covariance matrix; eigenvalue; eigenvector; fPCA; high dimensions; minimax rate; optimal rate of convergence; PCA; scree plot; sparsity
TL;DR:
It is shown that identifying jumps in the empirical spectrum that consistently estimate jumped in the spectrum of $\Sigma$ is not necessarily informative for other goals, for instance for the selection of those sample eigenvalues and eigenvectors that are consistent estimates of their population counterparts.
(via Semantic Scholar)
Source: ORCID
Added: January 15, 2020
2015 journal article
Factors Associated with Parent Concern for Child Weight and Parenting Behaviors
Childhood Obesity, 11(3), 269–274.
MeSH headings : Adolescent; Adult; Body Mass Index; Child; Educational Status; Female; Health Behavior; Health Knowledge, Attitudes, Practice; Humans; Male; Obesity / epidemiology; Obesity / prevention & control; Obesity / psychology; Parenting / psychology; Parents / education; Parents / psychology; Pennsylvania / epidemiology; Social Perception; Surveys and Questionnaires
TL;DR:
Results support the hypothesis that normal weight parents are more likely to engage in healthy behaviors and that overweight parents areMore likely to report concern about child weight, however, overweight parents are also morelikely to acknowledge overweight status in their own child.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 14, 2020
2015 journal article
Likelihood-based Inference with Missing Data Under Missing-at-Random
Scandinavian Journal of Statistics, 43(2), 436–454.
author keywords: confidence interval; fractional imputation; likelihood ratio; nonresponse; profile likelihood ratio
TL;DR:
This work has shown that approximating the integral by Monte Carlo sampling does not necessarily lead to a valid likelihood over the entire parameter space because the Monte Carlo samples are generated from a distribution with a fixed parameter value.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 14, 2020
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