Chemical and Biomolecular Engineering

Works Published in 2014

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Displaying works 21 - 40 of 236 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2014 journal article

Design of synthetic yeast promoters via tuning of nucleosome architecture

Nat Comms, 5.

By: K. Curran*, N. Crook*, A. Karim*, A. Gupta*, A. Wagman* & H. Alper*

MeSH headings : Gene Expression Regulation, Fungal; Models, Genetic; Mutation / genetics; Nucleosomes / metabolism; Promoter Regions, Genetic; Saccharomyces cerevisiae / genetics
TL;DR: It is demonstrated that nucleosome architecture can have a role in defining yeast promoter activity and a computationally-guided approach is utilized that can enable both the redesign of endogenous promoter sequences and the de novo design of synthetic promoters. (via Semantic Scholar)
Source: ORCID
Added: May 6, 2021

2014 journal article

Rapidly dissolving poly(vinyl alcohol)/cyclodextrin electrospun nanofibrous membranes

RSC Advances, 4(26), 13274–13279.

By: J. Manasco n, C. Tang n, N. Burns n, C. Saquing n & S. Khan n

TL;DR: It is found that PVA plays a synergistic role in facilitating fiber formation, enabling us to produce fibers with a high cyclodextrin content, and the amount of drug loading and the dissolution rate of the drug-containing fibers can be tuned by over two orders of magnitude by varying the HPβCD/PVA ratio. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Crossref
Added: March 27, 2021

2014 journal article

Foam electrospinning: A multiple jet, needle-less process for nanofiber production

AIChE Journal, 60(4), 1355–1364.

By: A. Higham n, C. Tang n, A. Landry n, M. Pridgeon n, E. Lee n, A. Andrady n, S. Khan n

author keywords: nanotechnology; electrospinning; nanofiber
UN Sustainable Development Goal Categories
Source: Crossref
Added: March 27, 2021

2014 journal article

Improved cell infiltration of highly porous 3D nanofibrous scaffolds formed by combined fiber–fiber charge repulsions and ultra-sonication

Journal of Materials Chemistry B, 2(46), 8116–8122.

By: S. Jeong*, N. Burns n, C. Bonino n, I. Kwon*, S. Khan n & E. Alsberg*

TL;DR: RD-modified alginate mats with increased thickness and porosity were achieved by pairing high humidity electrospinning with post-processing ultra-sonication, showing great promise for the design of cell-permeable nanofibrous scaffolds for tissue-engineering applications. (via Semantic Scholar)
Source: Crossref
Added: March 27, 2021

2014 journal article

Photo-activated ionic gelation of alginate hydrogel: real-time rheological monitoring of the two-step crosslinking mechanism

Soft Matter, 10(27), 4990–5002.

By: A. Higham n, C. Bonino n, S. Raghavan* & S. Khan n

MeSH headings : Alginates / chemistry; Alginates / radiation effects; Biphenyl Compounds / chemistry; Biphenyl Compounds / radiation effects; Calcium Carbonate / chemistry; Calcium Carbonate / radiation effects; Cross-Linking Reagents / chemistry; Cross-Linking Reagents / radiation effects; Elasticity; Glucuronic Acid / chemistry; Glucuronic Acid / radiation effects; Hexuronic Acids / chemistry; Hexuronic Acids / radiation effects; Hydrogels / chemistry; Onium Compounds / chemistry; Onium Compounds / radiation effects; Rheology; Ultraviolet Rays; Viscosity
TL;DR: The presence of dark curing is the result of the acidic environment persisting within the sample, allowing CaCO3 to dissociate, thereby releasing free Ca(2+) ions capable of binding with the available appropriate ionic blocks of the polymer chains. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Crossref
Added: March 27, 2021

2014 journal article

Metronomic docetaxel in PRINT® nanoparticles and EZH2 silencing have synergistic antitumor effect in ovarian cancer

Molecular Cancer Therapeutics, 13(7), 1750–1757.

By: K. Gharpure, K. Chu, C. Bowerman*, T. Miyake, S. Pradeep, S. Mangala*, H. Han*, R. Rupaimoole ...

MeSH headings : Administration, Metronomic; Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / chemistry; Cell Line, Tumor; Docetaxel; Enhancer of Zeste Homolog 2 Protein; Female; Gene Silencing / drug effects; Humans; Mice; Mice, Nude; Nanoparticles / administration & dosage; Nanoparticles / chemistry; Ovarian Neoplasms / drug therapy; Ovarian Neoplasms / genetics; Ovarian Neoplasms / metabolism; Ovarian Neoplasms / pathology; Polycomb Repressive Complex 2 / antagonists & inhibitors; Polycomb Repressive Complex 2 / genetics; Polycomb Repressive Complex 2 / metabolism; RNA, Small Interfering / administration & dosage; RNA, Small Interfering / genetics; Randomized Controlled Trials as Topic; Taxoids / administration & dosage; Taxoids / chemistry
TL;DR: Investigation of a combination of metronomic doses of a novel delivery vehicle, PLGA-PRINT nanoparticles containing docetaxel, and antiangiogenic mEZH2 siRNA incorporated into chitosan nanoparticles showed significant antitumor activity in preclinical models of ovarian cancer. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: January 3, 2021

2014 journal article

Using Targeted Chromatin Regulators to Engineer Combinatorial and Spatial Transcriptional Regulation

Cell, 158(1), 110–120.

MeSH headings : Chromatin / metabolism; Gene Expression Regulation, Fungal; Gene Regulatory Networks; Genes, Reporter; Saccharomyces cerevisiae / genetics; Saccharomyces cerevisiae / metabolism; Saccharomyces cerevisiae Proteins / chemistry; Saccharomyces cerevisiae Proteins / metabolism; Transcription, Genetic
TL;DR: A synthetic biology approach to decipher the complexity of chromatin regulation by studying emergent transcriptional behaviors from engineered combinatorial, spatial, and temporal patterns of individual CRs. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2014 journal article

Platelet-like Nanoparticles: Mimicking Shape, Flexibility, and Surface Biology of Platelets To Target Vascular Injuries

ACS Nano, 8(11), 11243–11253.

By: A. Anselmo*, C. Modery-Pawlowski*, S. Menegatti*, S. Kumar*, D. Vogus*, L. Tian*, M. Chen*, T. Squires*, A. Sen Gupta*, S. Mitragotri*

author keywords: platelets; synthetic cells; layer-by-layer; nanotechnology; hemostat; vascular targeting
MeSH headings : Animals; Blood Platelets / pathology; Cell Adhesion; Cell Shape; Female; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Nanoparticles; Platelet Aggregation; Spectroscopy, Fourier Transform Infrared; Vascular System Injuries / pathology
TL;DR: Platelet-like nanoparticles (PLNs) offer a nanoscale technology that integrates platelet-mimetic biophysical and biochemical properties for potential applications in injectable synthetic hemostats and vascularly targeted payload delivery. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020

2014 journal article

Production of lignofuels and electrofuels by extremely thermophilic microbes

Biofuels, 5(5), 499–515.

By: M. Keller*, A. Loder n, M. Basen*, J. Izquierdo n, R. Kelly n & M. Adams*

author keywords: extreme thermophiles; Pyrococcus furiosus; Metallosphaera sedula; Caldicellulosiruptor; biofuels; electrofuels; CO2 fixation; lignocellulose
TL;DR: Recent progress towards the synthesis of lignofuels and electrofuels by extremely thermophilic microorganisms is reviewed, including temperature-regulated biosynthesis of industrial organic chemicals and liquid fuel molecules. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: February 24, 2020

2014 journal article

Effect of ultraviolet/ozone treatment on the surface and bulk properties of poly(dimethyl siloxane) and poly(vinylmethyl siloxane) networks

Polymer, 55(14), 3107–3119.

By: A. Özçam n, K. Efimenko n & J. Genzer n

author keywords: Silicone elastomers; Surface modification; PDMS
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 21, 2020

2014 journal article

Electrospun Nanofibers for Design and Fabrication of Electrocatalysts and Electrolyte Membranes for Fuel cells

Electrospun Nanofibers for Energy and Environmental Applications.

Contributors: X. Zhang n, Y. Yao n & Z. Lin n

UN Sustainable Development Goal Categories
Source: ORCID
Added: October 15, 2019

2014 journal article

review of recent developments in membrane separators for rechargeable lithium-ion batteries

Energy & Environmental Science, 7.

By: H. Lee, M. Yanilmaz, O. Toprakci, K. Fu & X. Zhang

Source: ORCID
Added: August 15, 2019

2014 journal article

Tuning electrochemical performance of Si-based anodes for lithium-ion batteries by employing atomic layer deposition alumina coating

Journal of Materials Chemistry A, 2.

By: Y. Li, Y. Sun, G. Xu, Y. Lu, S. Zhang, L. Xue, J. Jur, X. Zhang

Source: ORCID
Added: August 15, 2019

2014 journal article

Sulfur gradient-distributed CNF composite: a self-inhibiting cathode for binder-free lithium-sulfur batteries

Chemical Communications, 50.

By: K. Fu, Y. Li, M. Dirican, C. Chen, Y. Lu, J. Zhu, Y. Li, L. Cao, P. Bradford, X. Zhang

Source: ORCID
Added: August 15, 2019

2014 journal article

One-dimensional SiOC/C composite nanofibers as binder-free anodes for lithium-ion batteries

Journal of Power Sources, 254.

By: Y. Li, Y. Hu, Y. Lu, S. Zhang, G. Xu, K. Fu, S. Li, C. Chen ...

Source: ORCID
Added: August 15, 2019

2014 journal article

Copper-doped Li4Ti5O12/carbon nanofiber composites as anode for high-performance sodium-ion batteries

Journal of Power Sources, 272.

By: Y. Ge, H. Jiang, K. Fu, C. Zhang, J. Zhu, C. Chen, Y. Lu, Y. Qiu, X. Zhang

Source: ORCID
Added: August 15, 2019

2014 journal article

Comparison of Si/C, Ge/C and Sn/C composite nanofiber anodes used in advanced lithium-ion batteries

Solid State Ionics, 254.

By: S. Li, C. Chen, K. Fu, L. Xue, C. Zhao, S. Zhang, Y. Hu, L. Zhou, X. Zhang

Source: ORCID
Added: August 15, 2019

2014 journal article

Centrifugal spinning: An alternative approach to fabricate nanofibers at high speed and low cost

Polymer Reviews, 54.

By: X. Zhang & Y. Lu

Source: ORCID
Added: August 15, 2019

2014 journal article

A model colloidal gel for coordinated measurements of force, structure, and rheology

Journal of Rheology, 58(5), 1485–1504.

By: L. Hsiao*, M. Solomon*, K. Whitaker* & E. Furst*

Sources: Crossref, NC State University Libraries
Added: July 27, 2019

2014 journal article

Role of shear-induced dynamical heterogeneity in the nonlinear rheology of colloidal gels

Soft Matter, 10(46), 9254–9259.

TL;DR: The effect of flow-induced dynamical heterogeneity on the nonlinear elastic modulus of weakly aggregated colloidal gels that have undergone yielding by an imposed step strain deformation is reported. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 27, 2019

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