Terri S. Hamrick

Works (7)

Updated: July 5th, 2023 16:02

2013 journal article

Extrauterine Listeriosis in the gravid mouse influences embryonic growth and development

PLoS One, 8(8).

By: M. Suyemoto, T. Hamrick, P. Spears, J. Horton, I. Washington, E. Havell, L. Borst , P. Orndorff

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

In Vitro Properties of a Listeria monocytogenes Bacteriophage-Resistant Mutant Predict Its Efficacy as a Live Oral Vaccine Strain

INFECTION AND IMMUNITY, 79(12), 5001–5009.

By: P. Spears n, M. Suyemoto n, T. Hamrick*, R. Wolf n, E. Havell n & P. Orndorff n

MeSH headings : Administration, Oral; Animals; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Bacterial Vaccines / administration & dosage; Bacterial Vaccines / immunology; Bacterial Vaccines / standards; Bacteriophages / physiology; Cells, Cultured; Enterocytes / microbiology; Female; Listeria monocytogenes / genetics; Listeria monocytogenes / virology; Listeriosis / microbiology; Listeriosis / prevention & control; Mice; Mice, Inbred BALB C; Mutagenesis, Insertional; Mutation; Time Factors; Vaccines, Attenuated / administration & dosage; Vaccines, Attenuated / standards
TL;DR: The results indicate that oral administration of a profoundly attenuated listeria monocytogenes glcV mutant can safely elicit solid protective immunity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

A Listeria monocytogenes mutant defective in bacteriophage attachment is attenuated in orally inoculated mice and impaired in enterocyte intracellular growth

INFECTION AND IMMUNITY, 76(9), 4046–4054.

By: P. Spears n, M. Suyemoto n, A. Palermo n, J. Horton n, T. Hamrick*, E. Havell n, P. Orndorff n

MeSH headings : Animals; Bacterial Adhesion; Bacteriophages / physiology; DNA Transposable Elements; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Enterocytes / microbiology; Female; Genetic Complementation Test; Glycosyltransferases / genetics; Listeria monocytogenes / pathogenicity; Listeria monocytogenes / virology; Listeriosis / microbiology; Liver / microbiology; Mice; Mice, Inbred A; Molecular Sequence Data; Mutagenesis, Insertional; Receptors, Virus / genetics; Sequence Analysis, DNA; Spleen / microbiology; Survival Analysis; Viral Plaque Assay; Virulence; Virulence Factors / genetics; Virus Attachment
TL;DR: Interestingly, the glcV lesion, while preventing phage attachment, did not alter the mutant's ability to bind to cultured mouse enterocyte monolayers, rather, the mutation appeared to alter a subsequent step in intracellular replication measured by a reduction in plaque-forming efficiency and plaque size. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2006 review

Host and bacterial factors in listeriosis pathogenesis

[Review of ]. VETERINARY MICROBIOLOGY, 114(1-2), 1–15.

By: P. Orndorff n, T. Hamrick*, I. Smoak n & E. Havell n

author keywords: listeria; pathogenesis; pregnancy; predisposition; veterinary
MeSH headings : Animals; Cytosol / microbiology; Disease Susceptibility / microbiology; Environment; Female; Food Microbiology; Humans; Immunity, Cellular / immunology; Listeria / growth & development; Listeria / pathogenicity; Listeriosis / immunology; Listeriosis / microbiology; Listeriosis / transmission; Mice; Pregnancy; Pregnancy Complications, Infectious / immunology; Pregnancy Complications, Infectious / microbiology; Vacuoles / microbiology
TL;DR: There are many features of the pathogenesis of listeriosis that have remained mysterious despite the extensive use of the microorganism in the study of cell-mediated immunity and intracellular growth, and Informational advances such as the sequence of the mouse and listerial genomes, and technical advancessuch as the discovery of listersia-susceptible mouse strains, may renew interest in the project. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Characterization of Escherichia coli type 1 pilus mutants with altered binding specificities

JOURNAL OF BACTERIOLOGY, 183(13), 4099–4102.

By: S. Harris n, P. Spears n, E. Havell n, T. Hamrick n, . Horton  n & P. Orndorff n

MeSH headings : Adhesins, Bacterial / genetics; Adhesins, Bacterial / metabolism; Adhesins, Escherichia coli; Alleles; Chromosomes, Bacterial; Escherichia coli / physiology; Fimbriae Proteins; Fimbriae, Bacterial / genetics; Fimbriae, Bacterial / metabolism; Molecular Sequence Data; Mutation; Phenotype; Plasmids; Recombination, Genetic
TL;DR: PCR mutagenesis and a unique enrichment scheme were used to obtain two mutants, each with a single lesion in fimH, the chromosomal gene that encodes the adhesin protein (FimH) of Escherichia coli type 1 pili that were noteworthy in part because both were altered in the normal range of cell types bound by FimH. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Genetic characterization of Escherichia coli type 1 pilus adhesin mutants and identification of a novel binding phenotype

JOURNAL OF BACTERIOLOGY, 182(14), 4012–4021.

By: T. Hamrick n, S. Harris n, P. Spears n, E. Havell n, . Horton  n, P. Russell n, P. Orndorff n

MeSH headings : Adhesins, Bacterial / genetics; Adhesins, Escherichia coli; Animals; Bacterial Adhesion / genetics; Base Sequence; Chromosome Mapping; Erythrocytes / microbiology; Escherichia coli / genetics; Escherichia coli / pathogenicity; Fimbriae Proteins; Guinea Pigs; Hemagglutination Tests; Macrophages / microbiology; Mice; Molecular Sequence Data; Phenotype; Point Mutation
TL;DR: Temperature shift experiments revealed that new FimH biosynthesis was required for the phenotypic change, and a temperature-sensitive (ts) fimH mutant that agglutinated guinea pig erythrocytes but not at 42 degrees C was chosen for further study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Host and bacterial factors involved in the innate ability of mouse macrophages to eliminate internalized unopsonized Escherichia coli

INFECTION AND IMMUNITY, 68(1), 125–132.

By: T. Hamrick n, E. Havell n, . Horton  n & P. Orndorff n

MeSH headings : Adhesins, Bacterial / immunology; Adhesins, Escherichia coli; Animals; Cell Line; Cytotoxicity, Immunologic; Escherichia coli / immunology; Fimbriae Proteins; Macrophages, Peritoneal / immunology; Macrophages, Peritoneal / microbiology; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Phagocytosis; Species Specificity
TL;DR: Host and bacterial factors involved in the nonopsonic phagocytosis and killing of Escherichia coli K-12 by mouse macrophages were examined to better understand genetic and cellular factors that influence innate immunity and there was no correlation between the bacteriocidal effectiveness of amacrophage population and the number of bacteria bound per macrophage. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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