Works (2)

Updated: July 5th, 2023 15:56

2017 journal article

Furosemide continuous rate infusion diluted with 5% dextrose in water or hypertonic saline in normal adult dogs: a pilot study

JOURNAL OF VETERINARY CARDIOLOGY, 19(1), 44–56.

By: D. Adin n, C. Atkins n, M. Papich n, T. DeFrancesco n, E. Griffiths n, M. Penteado*, K. Kurtz n, A. Klein n

author keywords: Lasix; Diuretic; Sodium; Salt
MeSH headings : Animals; Cross-Over Studies; Diuretics / administration & dosage; Diuretics / adverse effects; Diuretics / pharmacokinetics; Dogs; Furosemide / administration & dosage; Furosemide / adverse effects; Furosemide / pharmacokinetics; Glucose / administration & dosage; Infusions, Intravenous / veterinary; Male; Pilot Projects; Saline Solution, Hypertonic / administration & dosage; Single-Blind Method; Water
TL;DR: Diuresis was similar for both furosemide CRI methods; however, the H-SAL method induced less renin-angiotensin-aldosterone system activation than the DEX method, suggesting that dilution of a furo Semine CRI with 2.4% hypertonic saline may be well tolerated in heart failure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 journal article

Phase I trial of doxorubicin-containing low temperature sensitive liposomes in spontaneous canine tumors

CLINICAL CANCER RESEARCH, 12(13), 4004–4010.

By: M. Hauck n, S. LaRue*, W. Petros*, J. Poulson*, D. Yu, I. Spasojevic, A. Pruitt n, A. Klein n ...

MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / adverse effects; Antineoplastic Agents / pharmacokinetics; Carcinoma / therapy; Carcinoma / veterinary; Combined Modality Therapy; Dog Diseases / therapy; Dogs; Dose-Response Relationship, Drug; Doxorubicin / administration & dosage; Doxorubicin / adverse effects; Doxorubicin / pharmacokinetics; Drug Administration Schedule; Drug Delivery Systems; Female; Hyperthermia, Induced / methods; Liposomes; Male; Maximum Tolerated Dose; Microwaves / therapeutic use; Sarcoma / therapy; Sarcoma / veterinary; Temperature; Treatment Outcome
TL;DR: LTSL-doxorubicin offers a novel approach to improving drug delivery to solid tumors and was well tolerated and resulted in favorable response profiles in these patients. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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