Works (21)

Updated: February 22nd, 2026 05:07

2026 journal article

Establishment of a sedation threshold score for orthopedic radiographs in dogs and evaluation of inter-rater reliability and accuracy of video-based assessment

The Canadian Veterinary Journal, 67(2), 180–187.

By: R. Pinho, D. Pang, C. Leriquier, D. Gagnon, J. Benito & M. Freire

Source: NC State University Libraries
Added: February 20, 2026

2025 journal article

Use of a novel subcutaneous injection site in the region of acupuncture point GV20 for premedicating cats before general anesthesia

The Canadian Veterinary Journal, 66(5), 537–545.

By: B. Solash, J. Cheema, M. Freire, J. Benito & D. Pang

Source: NC State University Libraries
Added: February 20, 2026

2024 journal article

Clinical findings and prognostic factors for immediate survival in 33 dogs undergoing surgery for biliary peritonitis

Veterinary Surgery, 54(2), 276–286.

By: S. Renaud*, M. Freire*, E. O'Toole*, L. Huneault*, M. Llido*, B. Ringwood, T. Juette*, D. Gagnon*

MeSH headings : Animals; Dogs; Dog Diseases / surgery; Dog Diseases / mortality; Dog Diseases / diagnosis; Peritonitis / veterinary; Peritonitis / surgery; Peritonitis / mortality; Retrospective Studies; Male; Female; Prognosis; Postoperative Complications / veterinary; Postoperative Complications / mortality; Risk Factors; Biliary Tract Diseases / veterinary; Biliary Tract Diseases / surgery; Biliary Tract Diseases / mortality
topics (OpenAlex): Gallbladder and Bile Duct Disorders; Pancreatitis Pathology and Treatment; Pediatric Hepatobiliary Diseases and Treatments
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 20, 2026

2024 journal article

Comparison of sedation with dexmedetomidine administered subcutaneously at 2 different locations on the head in dogs

The Canadian Veterinary Journal, 65(4), 351–358.

By: M. Llido, C. Leriquier, T. Juette, J. Benito & M. Freire

Source: NC State University Libraries
Added: February 20, 2026

2024 journal article

Subclinical bacteriuria and surgical-site infection in 140 dogs with orthopedic and neurological conditions

The Canadian Veterinary Journal, 65(12), 1253–1259.

By: M. Porcel Sánchez, D. Gagnon, B. Brisson, K. Hoddinott, T. Juette & M. Freire

Source: NC State University Libraries
Added: February 20, 2026

2023 journal article

Comparison of sedation with dexmedetomidine/atipamezole administered subcutaneously at GV20 acupuncture point with usual routes of administration in dogs presented for orthopaedic radiographs

Journal of Small Animal Practice, 64(12), 759–768.

By: C. Leriquier*, M. Freire*, M. Llido*, G. Beauchamp*, X. Montasell*, D. Gagnon*, J. Benito*

MeSH headings : Animals; Dogs; Acupuncture Points; Dexmedetomidine / administration & dosage; Dexmedetomidine / adverse effects; Double-Blind Method; Hypnotics and Sedatives / administration & dosage; Hypnotics and Sedatives / adverse effects; Orthopedics; Prospective Studies; Dog Diseases / diagnostic imaging; Injections, Subcutaneous / methods
topics (OpenAlex): Anesthesia and Sedative Agents; Veterinary Pharmacology and Anesthesia; Acupuncture Treatment Research Studies
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries, ORCID
Added: October 10, 2025

2023 journal article

Effects of Transfixation Pin Positioning on the Biomechanical Properties of Acrylic External Skeletal Fixators in a Fracture Gap Model

Veterinary and Comparative Orthopaedics and Traumatology, 36(06), 273–278.

By: J. Lahiani*, M. Freire*, X. Montasell, T. Juette* & D. Gagnon*

MeSH headings : Animals; Biomechanical Phenomena; Fractures, Bone / surgery; Fractures, Bone / veterinary; External Fixators; Bone Nails; Cadaver
topics (OpenAlex): Bone fractures and treatments; Hip and Femur Fractures; Pelvic and Acetabular Injuries
Sources: Crossref, NC State University Libraries
Added: February 20, 2026

2022 journal article

A disposable, canister-free negative-pressure wound therapy device proves feasible, but of inferior efficacy to conventional therapies for treating cutaneous wounds in dogs

American Journal of Veterinary Research, 83(10).

By: M. Freire*, C. Job*, I. Hassanpour*, J. Benito*, D. Pang*, M. Paquet*, C. Theoret*

MeSH headings : Animals; Bandages / veterinary; Dogs; Female; Granulation Tissue; Negative-Pressure Wound Therapy / veterinary; Skin; Wound Healing
topics (OpenAlex): Wound Healing and Treatments; Surgical Sutures and Adhesives; Surgical site infection prevention
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries, ORCID
Added: October 10, 2025

2022 journal article

Surgical correction of left auricular aneurysm herniation through a pericardial defect in a dog with atrial fibrillation and mitral valve disease

Veterinary Record Case Reports, 10(3).

By: M. Freire*, B. Conversy*, J. De Lasalle, P. Fontaine, F. Rousseau‐Blass* & D. Pang*

topics (OpenAlex): Cardiovascular Conditions and Treatments; Cardiac Arrhythmias and Treatments; Coronary Artery Anomalies
Sources: ORCID, Crossref, NC State University Libraries
Added: February 20, 2026

2020 journal article

Uretero-Cutaneous Fistula and Renal Abscessation as a Complication of Ureteral Stenting in a Dog

Journal of the American Animal Hospital Association, 56(3), e563–03.

By: X. Montasell, M. Dunn & M. Freire*

MeSH headings : Abscess / etiology; Abscess / veterinary; Animals; Cutaneous Fistula / diagnosis; Cutaneous Fistula / etiology; Cutaneous Fistula / veterinary; Diagnosis, Differential; Dog Diseases / diagnosis; Dog Diseases / etiology; Dog Diseases / surgery; Dogs; Female; Kidney Diseases / diagnosis; Kidney Diseases / etiology; Kidney Diseases / veterinary; Postoperative Complications / diagnosis; Postoperative Complications / etiology; Postoperative Complications / veterinary; Stents / adverse effects; Stents / veterinary; Ureteral Diseases / diagnosis; Ureteral Diseases / etiology; Ureteral Diseases / veterinary; Ureteral Obstruction / surgery; Ureteral Obstruction / veterinary
topics (OpenAlex): Pediatric Urology and Nephrology Studies; Veterinary Medicine and Surgery; Renal and Vascular Pathologies
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 20, 2026

2019 journal article

Transvaginal uterine evisceration during labor in a Bengal queen

Journal of Feline Medicine and Surgery Open Reports, 5(2).

By: M. Freire* & M. Diaw*

topics (OpenAlex): Urological Disorders and Treatments; Veterinary Medicine and Surgery; Hernia repair and management
Sources: Crossref, NC State University Libraries
Added: February 20, 2026

2018 journal article

Characterization of gene expression in naturally occurring feline degenerative joint disease-associated pain

The Veterinary Journal, 243, 42–47.

By: M. Ashwell n, M. Freire n, A. O’Nan n, J. Benito n, J. Hash n, R. McCulloch*, B. Lascelles n

author keywords: Cat; Degenerative joint disease; Neurobiological signature; Osteoarthritis; Pain
MeSH headings : Animals; Cat Diseases / genetics; Cats; Female; Ganglia, Spinal / metabolism; Ganglia, Spinal / physiopathology; Gene Expression; Gene Expression Profiling; Lumbosacral Region / physiopathology; Male; Osteoarthritis, Spine / veterinary; Pain / genetics; Pain / veterinary; Spinal Cord Dorsal Horn / metabolism; Spinal Cord Dorsal Horn / physiopathology
topics (OpenAlex): Veterinary Orthopedics and Neurology; Veterinary Equine Medical Research; Osteoarthritis Treatment and Mechanisms
Sources: Crossref, NC State University Libraries, Web Of Science, ORCID
Added: February 11, 2019

2018 journal article

Chylous ascites associated with abdominal trauma and intestinal resection-anastomosis in a pet ferret (Mustela putorius furo)

Journal of the American Veterinary Medical Association, 252(10), 1272–1278.

By: L. Chassang, I. Langlois, P. Loos, M. Freire* & E. O'Toole

MeSH headings : Abdominal Injuries / surgery; Abdominal Injuries / veterinary; Anastomosis, Surgical / adverse effects; Anastomosis, Surgical / veterinary; Animals; Chylous Ascites / diagnosis; Chylous Ascites / etiology; Chylous Ascites / veterinary; Diagnosis, Differential; Ferrets / injuries; Male; Pets
topics (OpenAlex): Lymphatic Disorders and Treatments; Gastrointestinal disorders and treatments; Congenital Diaphragmatic Hernia Studies
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 20, 2026

2016 journal article

Comparison of thermal and mechanical quantitative sensory testing in client-owned dogs with chronic naturally occurring pain and normal dogs

The Veterinary Journal, 210, 95–97.

By: M. Freire n, D. Knazovicky n, B. Case n, A. Thomson n & B. Lascelles n

Contributors: M. Freire n, D. Knazovicky n, B. Case n, A. Thomson n & B. Lascelles n

author keywords: Canine; Central Sensitization; Chronic pain; Mechanical sensory threshold; Thermal sensory threshold
MeSH headings : Animals; Central Nervous System Sensitization; Dog Diseases / physiopathology; Dogs; Osteoarthritis / physiopathology; Osteoarthritis / veterinary; Pain / physiopathology; Pain / veterinary; Sensory Thresholds
topics (OpenAlex): Veterinary Orthopedics and Neurology; Veterinary Equine Medical Research; Veterinary Pharmacology and Anesthesia
TL;DR: Whether QST is different between dogs with chronic pain and normal dogs needs further investigation using a larger group of animals and age, weight and sex matched groups. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 25, 2020

2015 journal article

A canine-specific anti-nerve growth factor antibody alleviates pain and improves mobility and function in dogs with degenerative joint disease-associated pain

BMC Veterinary Research, 11(1), 101.

By: B. Lascelles n, D. Knazovicky n, B. Case n, M. Freire*, J. Innes, A. Drew*, D. Gearing*

Contributors: B. Lascelles n, D. Knazovicky n, B. Case n, M. Freire*, J. Innes, A. Drew*, D. Gearing*

author keywords: Nerve growth factor; Dog; Antibody; Pain; Model; Osteoarthritis; Accelerometry; Actimetry
MeSH headings : Animals; Antibodies / immunology; Antibodies / therapeutic use; Dog Diseases / therapy; Dogs; Double-Blind Method; Female; Immunotherapy / veterinary; Male; Nerve Growth Factor / immunology; Osteoarthritis / therapy; Osteoarthritis / veterinary; Pain / drug therapy; Pain / veterinary
topics (OpenAlex): Veterinary Orthopedics and Neurology; Tendon Structure and Treatment; Veterinary Equine Medical Research
TL;DR: These pilot data demonstrate a positive analgesic effect of anti-NGF antibody in dogs suffering from chronic pain, similar to that expected with an NSAID. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Pathology of Articular Cartilage and Synovial Membrane From Elbow Joints With and Without Degenerative Joint Disease in Domestic Cats

Veterinary Pathology, 51(5), 968–978.

By: M. Freire n, D. Meuten n & D. Lascelles n

author keywords: degenerative joint disease; elbow joint; feline; histopathology; medial compartment joint disease; synovial osteochondromatosis
MeSH headings : Animals; Bone and Bones / pathology; Cartilage, Articular / anatomy & histology; Cartilage, Articular / pathology; Cat Diseases / pathology; Cats; Female; Forelimb / anatomy & histology; Forelimb / pathology; Joint Diseases / pathology; Joint Diseases / veterinary; Joints / anatomy & histology; Joints / pathology; Male; Severity of Illness Index; Synovial Membrane / anatomy & histology; Synovial Membrane / pathology
topics (OpenAlex): Musculoskeletal synovial abnormalities and treatments; Tendon Structure and Treatment; Elbow and Forearm Trauma Treatment
TL;DR: Lesions observed in these animals are most consistent with synovial osteochondromatosis secondary to degenerative joint disease, but a fragmented medial coronoid process or osteochondritis dissecans does not appear to play a role. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Evaluation of the clinical use of tepoxalin and meloxicam in cats

Journal of Feline Medicine and Surgery, 15(8), 678–690.

By: A. Charlton n, J. Benito n, W. Simpson*, M. Freire n & B. Lascelles n

MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / therapeutic use; Cat Diseases / drug therapy; Cats; Female; Male; Meloxicam; Pyrazoles / adverse effects; Pyrazoles / therapeutic use; Retrospective Studies; Thiazines / adverse effects; Thiazines / therapeutic use; Thiazoles / adverse effects; Thiazoles / therapeutic use
topics (OpenAlex): Inflammatory mediators and NSAID effects; Adrenal Hormones and Disorders; Veterinary Equine Medical Research
TL;DR: Tepoxalin and meloxicam are well tolerated in the clinical setting at the doses prescribed in this study, and several statistically significant changes for serum biochemistry and hematology parameters were within normal limits. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Feasibility and repeatability of cold and mechanical quantitative sensory testing in normal dogs

The Veterinary Journal, 199(2), 245–250.

By: J. Briley n, M. Williams n, M. Freire n, E. Griffith n & B. Lascelles n

author keywords: Canine; Quantitative sensory testing; Pressure algometer; Electronic von Frey anesthesiometer
MeSH headings : Animals; Cold Temperature; Dogs / physiology; Electrical Equipment and Supplies / veterinary; Feasibility Studies; Female; Male; Mechanoreceptors / physiology; Pain Measurement / methods; Reproducibility of Results; Sensation / physiology; Sensory Thresholds / physiology
topics (OpenAlex): Veterinary Equine Medical Research; Infrared Thermography in Medicine; Meat and Animal Product Quality
TL;DR: Both mechanical QST devices tested provided repeatable, reliable sensory threshold measurements in normal, client-owned dogs and contribute to the validation of the EVF and PA as tools to obtain repeated QST data over time in dogs to assess somatosensory processing changes. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Cross-Sectional Study of the Prevalence of Radiographic Degenerative Joint Disease in Domesticated Cats

Veterinary Surgery, 39(5), 535–544.

By: B. Lascelles n, J. Henry III n, J. Brown n, I. Robertson n, A. Sumrell n, W. Simpson*, S. Wheeler n, B. Hansen n ...

MeSH headings : Age Factors; Animals; Cat Diseases / diagnostic imaging; Cat Diseases / epidemiology; Cats; Cross-Sectional Studies; Female; Joint Diseases / diagnostic imaging; Joint Diseases / epidemiology; Joint Diseases / veterinary; Male; Poisson Distribution; Prevalence; Prospective Studies; Radiography
topics (OpenAlex): Veterinary Orthopedics and Neurology; Veterinary Oncology Research; Hypertrophic osteoarthropathy and related conditions
TL;DR: Radiographically visible DJD is very common in domesticated cats, even in young animals and is strongly associated with age, which requires further investigation of its associated clinical signs. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Meniscal Mineralization in Domestic Cats

Veterinary Surgery, 39(5), 545–552.

By: M. Freire n, J. Brown n, I. Robertson n, A. Pease n, J. Hash n, S. Hunter n, W. Simpson*, A. Thomson Sumrell n, B. Lascelles n

MeSH headings : Age Factors; Animals; Calcinosis / diagnostic imaging; Calcinosis / pathology; Calcinosis / veterinary; Cat Diseases / diagnostic imaging; Cat Diseases / pathology; Cats; Female; Joint Diseases / diagnostic imaging; Joint Diseases / pathology; Joint Diseases / veterinary; Male; Menisci, Tibial / diagnostic imaging; Menisci, Tibial / pathology; Pain Measurement / veterinary; Prospective Studies; Radiography; Stifle / diagnostic imaging; Stifle / pathology
topics (OpenAlex): Veterinary Equine Medical Research; Veterinary Orthopedics and Neurology; Veterinary Medicine and Surgery
TL;DR: Meniscal mineralization is a common condition in domestic cats and seems to indicate medial compartment DJD, which is a cause, or a consequence of joint degeneration, in dogs. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, Web Of Science, ORCID
Added: August 6, 2018

2008 journal article

Efficacy of tolfenamic acid and meloxicam in the control of postoperative pain following ovariohysterectomy in the cat

Veterinary Anaesthesia and Analgesia, 35(6), 501–510.

By: J. Benito-de-la-Víbora*, B. Lascelles n, P. García-Fernández*, M. Freire* & I. Gómez de Segura*

MeSH headings : Analgesics / therapeutic use; Animals; Cats / surgery; Female; Hysterectomy / adverse effects; Hysterectomy / veterinary; Meloxicam; Ovariectomy / adverse effects; Ovariectomy / veterinary; Pain Measurement / veterinary; Pain, Postoperative / drug therapy; Pain, Postoperative / veterinary; Thiazines / therapeutic use; Thiazoles / therapeutic use; ortho-Aminobenzoates / therapeutic use
topics (OpenAlex): Veterinary Pharmacology and Anesthesia; Veterinary Equine Medical Research; Anesthesia and Pain Management
TL;DR: Tolfenamic acid and meloxicam administered preoperatively provided a similar analgesic effect in the postoperative period lasting 24 hours, suggesting mechanical thresholds may be a better way of evaluating postoperative analgesia provided by nonsteroidal anti-inflammatory drugs in cats. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, NC State University Libraries, ORCID
Added: August 6, 2018

Employment

Updated: February 20th, 2026 12:31

2025 - present

North Carolina State University Raleigh, North Carolina, US
Associate Professor Orthopedics Clinical Sciences

2014 - 2025

University of Montreal Montreal, Quebec, CA
Associate Professor Small Animal Surgery Clinical Sciences

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