Works Published in 1996
Displaying works 81 - 84 of 84 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
1996 journal article
The use of mechanistically defined chemical mixtures (MDCM) to assess mixture component effects on the percutaneous absorption and cutaneous disposition of topically exposed chemicals .2. Development of a general dermatopharmacokinetic model for use in risk assessment
TOXICOLOGY AND APPLIED PHARMACOLOGY, 141(2), 487–496.
MeSH headings : Animals; Models, Biological; Perfusion; Risk Assessment; Skin / metabolism; Skin Absorption; Swine
TL;DR:
This model supports the MDCM concept that defining and then simulating those components of a complex mixture that could have a significant impact on the absorption of a marker toxic compound would be a useful screening approach in the risk assessment of topical chemical mixtures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1996 journal article
The use of mechanistically defined chemical mixtures (MDCM) to assess component effects on the percutaneous absorption and cutaneous disposition of topically exposed chemicals .1. Studies with parathion mixtures in isolated perfused porcine skin
TOXICOLOGY AND APPLIED PHARMACOLOGY, 141(2), 473–486.
MeSH headings : Animals; Dimethyl Sulfoxide / pharmacology; Female; Insecticides / pharmacokinetics; Parathion / pharmacokinetics; Perfusion; Risk Assessment; Skin / blood supply; Skin / metabolism; Skin Absorption; Surface-Active Agents / pharmacology; Swine
TL;DR:
This study indicated multiple levels of interactive effects on PA absorption which must be incorporated into any effort to identify critical mechanisms which affect risk assessment of topically exposed mixtures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
1996 chapter
The pig as a model for cutaneous pharmacology and toxicology research
In M. E. Tumbleson & L. B. Schook (Eds.), Advances in swine in biomedical research (pp. 425–458).
Ed(s): . M. E. Tumbleson & L. Schook
TL;DR:
The pig has been a well accepted model for cutaneous absorption and toxicity studies because the integument is morphologically and functionally similar to human skin, and how the pig is utilized in this field is reviewed, with particular reference to studies conducted in the laboratory.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018
1996 conference paper
Integrated biochemical and molecular mechanisms of sulfur mustard vesication in skin: vascular and basement membrane targets
Proceedings of the 1996 Medical Defense Bioscience Review, 977–986. Aberdeen, MD: U.S. Army Medical Research Institute of Chemical Defense.
Source: NC State University Libraries
Added: August 6, 2018
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