Center for Environmental and Health Effects of PFAS

Works Published in 2005

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Displaying works 21 - 40 of 67 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2005 journal article

Déjà Vu All Over Again: Skin Cap Still Contains a High-Potency Glucocorticosteroid

Archives of Dermatology, 141(6).

By: D. Swanson, M. Pittelkow, L. Benson, A. Hawkridge & D. Muddiman*

MeSH headings : Administration, Topical; Adrenal Cortex Hormones / adverse effects; Adrenal Cortex Hormones / chemistry; Adrenal Cortex Hormones / therapeutic use; Chemistry, Pharmaceutical; Dermatologic Agents / adverse effects; Dermatologic Agents / pharmacology; Dermatologic Agents / therapeutic use; Female; Humans; Male; Materials Testing; Psoriasis / diagnosis; Psoriasis / drug therapy; Risk Assessment; Sensitivity and Specificity
Sources: Crossref, NC State University Libraries
Added: August 28, 2020

2005 conference paper

Multipopulation cooperative coevolutionary programming (MCCP) to enhance design innovation

Proceedings of the 2005 conference on Genetic and evolutionary computation - GECCO '05. Presented at the the 2005 conference.

By: E. Zechman n & S. Ranjithan n

Event: the 2005 conference

TL;DR: An evolutionary algorithm called Multipopulation Cooperative Coevolutionary Programming (MCCP) is described, that extends Genetic Programming to search for a set of maximally different solutions for program induction problems to yield potentially more creative designs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 28, 2020

2005 journal article

Quantitative mass spectral evidence for the absence of circulating brain natriuretic peptide (BNP-32) in severe human heart failure

Proceedings of the National Academy of Sciences, 102(48), 17442–17447.

By: A. Hawkridge*, D. Heublein*, H. Bergen*, A. Cataliotti*, J. Burnett* & D. Muddiman*

author keywords: biomarkers; electrospray ionization; Fourier transform-ion cyclotron resonance MS; immunoaffinity purification; targeted proteomics
MeSH headings : Chromatography, Liquid; Female; Heart Failure / metabolism; Humans; Isotope Labeling; Male; Mass Spectrometry; Natriuretic Peptide, Brain / blood; Natriuretic Peptide, Brain / isolation & purification
TL;DR: An immunoaffinity purification assay is developed and used to isolate endogenous BNP-32 from New York Heart Association class IV patient plasma for subsequent analysis by nano-liquid chromatography (LC) electrospray ionization Fourier transform ion cyclotron resonance (FT-ICR) MS. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020

2005 journal article

Evaluation of Protein Depletion Methods for the Analysis of Total-, Phospho- and Glycoproteins in Lumbar Cerebrospinal Fluid

Journal of Proteome Research, 4(3), 837–845.

By: Y. Ogata*, M. Charlesworth* & D. Muddiman*

author keywords: cerebrospinal fluid; human; two-dimensional gel electrophoresis; mass spectrometry; glycoprotein; phosphoprotein; protein depletion; low-abundance protein
MeSH headings : Adult; Aged; Cerebrospinal Fluid Proteins / analysis; Cerebrospinal Fluid Proteins / classification; Cerebrospinal Fluid Proteins / isolation & purification; Chromatography, Affinity; Electrophoresis, Gel, Two-Dimensional; Female; Fluorescent Dyes; Glycoproteins / cerebrospinal fluid; Glycoproteins / isolation & purification; Humans; Immunoglobulins; Male; Mass Spectrometry; Methods; Microspheres; Middle Aged; Phosphoproteins / cerebrospinal fluid; Phosphoproteins / isolation & purification
TL;DR: Phospho- and glycoprotein specific fluorescent stains and mass spectrometry were used to map proteins from CSF on two-dimensional gel electropherograms after immunoaffinity based protein removal, and fifty proteins were identified from 66 spots, and 12 proteins have not been annotated in previously published 2D gels. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020

2005 journal article

Coordination-Driven Self-Assemblies with a Carborane Backbone

Journal of the American Chemical Society, 127(34), 12131–12139.

By: H. Jude*, H. Disteldorf*, S. Fischer*, T. Wedge*, A. Hawkridge*, A. Arif*, M. Hawthorne*, D. Muddiman*, P. Stang*

MeSH headings : Boranes / chemistry; Crystallography, X-Ray; Isotope Labeling; Magnetic Resonance Spectroscopy; Molecular Structure; Pyridines / chemistry; Spectrometry, Mass, Electrospray Ionization
TL;DR: Isotopically resolved mass spectrometry data confirm the existence of the rectangle, triangle, and hexagon, and NMR data are consistent with the formation of all five assemblies. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020

2005 journal article

Gentle Protein Ionization Assisted by High-Velocity Gas Flow

Analytical Chemistry, 77(19), 6174–6183.

By: P. Yang*, R. Cooks, Z. Ouyang, A. Hawkridge & D. Muddiman*

MeSH headings : Cytochromes c / chemistry; Hydrogen-Ion Concentration; Ions / chemistry; Myoglobin / chemistry; Proteins / chemistry; Spectrometry, Mass, Electrospray Ionization / instrumentation; Spectrometry, Mass, Electrospray Ionization / methods; Ubiquitin / chemistry
TL;DR: Evidence is provided for the importance of the conditions used in the desolvation process for the preservation of the protein conformation and suggest that the conditions achieved when using high-velocity gas flows to assist droplet evaporation and ion Desolvation are much gentler than those in conventional ESI experiments. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020

2005 journal article

Statistical Evaluation of Internal and External Mass Calibration Laws Utilized in Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

Analytical Chemistry, 77(8), 2406–2414.

MeSH headings : Calibration; Cyclotrons; Data Interpretation, Statistical; Fourier Analysis; Polymers / analysis; Polymers / chemistry; Propylene Glycols / analysis; Propylene Glycols / chemistry; Quaternary Ammonium Compounds / chemistry; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization / methods
TL;DR: The statistical evaluation of two common and three new calibration laws utilized in Fourier transform ion cyclotron resonance mass spectrometry are presented and the number of calibrant ions as well as their required m/z range is investigated in order to successfully achieve high MMA. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020

2005 journal article

Derivatives of pentamidine designed to target the Leishmania lipophosphoglycan

Tetrahedron Letters, 46(4), 695–698.

By: K. Kramp*, K. DeWitt*, J. Flora*, D. Muddiman*, K. Slunt* & T. Houston*

author keywords: boronate drug targeting; pentamidine; Leishmania
TL;DR: Pentamidine has been modified with boronic acids so that it might bind more selectively to the phosphodisaccharide repeating unit of the LPG, which could serve to target the drug to the protozoan surface and increase its efficacy in vivo. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020

2005 journal article

Leveling response factors in the electrospray ionization process using a heated capillary interface

Journal of the American Society for Mass Spectrometry, 16(5), 772–778.

By: J. Frahm*, D. Muddiman* & M. Burke*

MeSH headings : Capillary Action; DNA / analysis; DNA / chemistry; Equipment Design; Equipment Failure Analysis; Hot Temperature; Humans; Specimen Handling / instrumentation; Specimen Handling / methods; Spectrometry, Mass, Electrospray Ionization / instrumentation; Spectrometry, Mass, Electrospray Ionization / methods
TL;DR: The implementation of a heated electrospray source was used to denature amplicons containing 7-deaza purines, which can be used to facilitate sequencing by mass spectrometry. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020

2005 journal article

Normalization of relative peptide ratios derived from in-gel digests: applications to protein variant analysis at the peptide level

Rapid Communications in Mass Spectrometry, 19(19), 2871–2877.

By: H. Bergen*, D. Muddiman*, J. O'Brien* & J. Hoyer*

MeSH headings : Algorithms; Chromatography, High Pressure Liquid / methods; Gas Chromatography-Mass Spectrometry / methods; Gas Chromatography-Mass Spectrometry / standards; Humans; Osmotic Fragility; Peptide Mapping / methods; Peptide Mapping / standards; Reference Values; Reproducibility of Results; Sensitivity and Specificity; Spectrin / analysis; Spectrin / chemistry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR: A strategy was developed to normalize for sample variability due to ionization efficiency, solvent effects, digestion and extraction efficiency by utilizing multiple isotopically labeled internal standards for multiple peptides derived from the same protein. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020

2005 journal article

Effect of post-excitation radius on ion abundance, mass measurement accuracy, and isotopic distributions in Fourier transform ion cyclotron resonance mass spectrometry

Rapid Communications in Mass Spectrometry, 19(7), 915–918.

By: A. Hawkridge*, A. Nepomuceno*, S. Lovik*, C. Mason* & D. Muddiman*

MeSH headings : Bradykinin / analysis; Ions; Isotopes; Reproducibility of Results; Spectroscopy, Fourier Transform Infrared / instrumentation; Spectroscopy, Fourier Transform Infrared / methods; Tritium
TL;DR: The findings presented herein underscore the importance of determining the optimal post-excitation radius in FT-ICR-MS to achieve high ion abundance (low limits of detection), high MMA, and valid isotopic distributions. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020

2005 conference paper

Investigation and Demonstration of an Evolutionary Computation-Based Model Correction Procedure for a Numerical Simulation Model

Impacts of Global Climate Change. Presented at the World Water and Environmental Resources Congress 2005.

By: E. Zechman n, G. Mahinthakumar n & S. Ranjithan n

Event: World Water and Environmental Resources Congress 2005

Sources: Crossref, NC State University Libraries
Added: February 24, 2020

2005 conference paper

A Genetic Programming-Based Surrogate Model Development and Its Application to a Groundwater Source Identification Problem

Impacts of Global Climate Change. Presented at the World Water and Environmental Resources Congress 2005.

By: E. Zechman n, B. Mirghani n, G. Mahinthakumar n & S. Ranjithan n

Event: World Water and Environmental Resources Congress 2005

TL;DR: This paper investigates a groundwater source identification problem in which chemical signals at observation wells are used to reconstruct the pollution loading scenario using a simulation-optimization approach that uses a genetic algorithm to conduct the search. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020

2005 journal article

Structure of hybrid polyhedral oligomeric silsesquioxane propyl methacrylate oligomers using ion mobility mass spectrometry and molecular mechanics

Chemistry of Materials, 17(10), 2537–2545.

By: S. Anderson*, E. Baker*, C. Mitchell*, T. Haddad* & M. Bowers*

Contributors: S. Anderson*, E. Baker*, C. Mitchell*, T. Haddad* & M. Bowers*

UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: ORCID
Added: December 5, 2019

2005 journal article

Structural motifs of DNA complexes in the gas phase

International Journal of Mass Spectrometry, 240(3), 183–193.

By: J. Gidden*, E. Baker*, A. Ferzoco* & M. Bowers*

Contributors: J. Gidden*, E. Baker*, A. Ferzoco* & M. Bowers*

author keywords: ion mobility; DNA; helix; conformations
Source: ORCID
Added: December 5, 2019

2005 journal article

Structural characterization of G-quadruplexes in deoxyguanosine clusters using ion mobility mass spectrometry

Journal of the American Society For Mass Spectrometry, 16(7), 989–997.

Contributors: E. Baker*, S. Bernstein* & M. Bowers*

MeSH headings : Deoxyguanosine / chemistry; Molecular Structure; Nanotechnology; Spectrometry, Mass, Electrospray Ionization / methods
TL;DR: The aggregation and conformation of deoxyguanosine in an ammonium acetate buffer solution were examined and results provide compelling evidence that quadruplexes are present in solution and retain their structure during the spray process, dehydration, and detection. (via Semantic Scholar)
Source: ORCID
Added: December 5, 2019

2005 journal article

Structural analysis of metal interactions with the dinucleotide duplex, dCG center dot dCG, using ion mobility mass spectrometry

Journal of Physical Chemistry B, 109(11), 4808–4810.

By: E. Baker*, M. Manard*, J. Gidden* & M. Bowers*

Contributors: E. Baker*, M. Manard*, J. Gidden* & M. Bowers*

MeSH headings : Mass Spectrometry / methods; Metals / chemistry; Nucleotides / chemistry
TL;DR: The metal binding properties of the dinucleotide duplex, dCG x dCG, were analyzed in the gas phase with ion mobility mass spectrometry and a structure was observed where the two C-G base pairs were Watson-Crick bound. (via Semantic Scholar)
Source: ORCID
Added: December 5, 2019

2005 journal article

Probing shapes of bichromophoric metal-organic complexes using ion mobility mass spectrometry

Journal of the American Chemical Society, 127(51), 18222–18228.

By: E. Baker*, J. Bushnell*, S. Wecksler*, M. Lim*, M. Manard*, N. Dupuis*, P. Ford*, M. Bowers*

Contributors: E. Baker*, J. Bushnell*, . Wecksler*, M. Lim*, M. Manard*, N. Dupuis*, P. Ford*, M. Bowers*

TL;DR: DFT structures, in good agreement with the IM-MS cross sections, indicate two "bent" conformations with the planes of the porphyrin and Fe2S2 rings at different angles with respect to each other. (via Semantic Scholar)
Source: ORCID
Added: December 5, 2019

2005 journal article

Re: "Cancer incidence among pesticide applicators exposed to alachlor in the agricultural health study" [2] (multiple letters)

American Journal of Epidemiology, 161(1), 101–103.

By: C. Poole*, M. Cullen*, R. Irons*, J. Acquavella*, W. Lee, J. Hoppin, A. Blair, J. Lubin ...

Contributors: C. Poole*, M. Cullen*, R. Irons*, J. Acquavella*, W. Lee, J. Hoppin, A. Blair, J. Lubin ...

MeSH headings : Acetamides; Adult; Agricultural Workers' Diseases / epidemiology; Causality; Female; Herbicides; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; Neoplasms / epidemiology; North Carolina / epidemiology; Occupational Exposure / statistics & numerical data; Reference Values
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: ORCID
Added: September 13, 2019

2005 journal article

Pesticide Use and Breast Cancer Risk among Farmers' Wives in the Agricultural Health Study

American Journal of Epidemiology, 161(2), 121–135.

By: L. Engel*, D. Hill*, J. Hoppin*, J. Lubin*, C. Lynch*, J. Pierce, C. Samanic*, D. Sandler*, A. Blair*, M. Alavanja*

Contributors: L. Engel*, D. Hill*, J. Hoppin*, J. Lubin*, C. Lynch*, J. Pierce, C. Samanic*, D. Sandler*, A. Blair*, M. Alavanja*

author keywords: agriculture; agrochemicals; breast neoplasms; fungicides; industrial; herbicides; insecticides; pesticides; risk
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases / chemically induced; Breast Neoplasms / chemically induced; Female; Follow-Up Studies; Humans; Iowa; Life Style; Male; Middle Aged; North Carolina; Occupational Exposure / adverse effects; Pesticides / adverse effects; Prospective Studies; Reproductive History; Risk Factors; Spouses
TL;DR: The authors found no clear association of breast cancer risk with farm size or washing of clothes worn during pesticide application, but risk was modestly elevated among women whose homes were closest to areas of pesticide application. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

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