Works Published in 2015

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Displaying works 181 - 200 of 259 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2015 journal article

Testing in Microbiome-Profiling Studies with MiRKAT, the Microbiome Regression-Based Kernel Association Test

AMERICAN JOURNAL OF HUMAN GENETICS, 96(5), 797–807.

By: N. Zhao*, J. Chen*, I. Carroll*, T. Ringel-Kulka*, M. Epstein*, H. Zhou n, J. Zhou*, Y. Ringel*, H. Li*, M. Wu*

MeSH headings : Computer Simulation; Genetics, Population; High-Throughput Nucleotide Sequencing; Humans; Microbiota / genetics; Models, Statistical; Phylogeny; Polymorphism, Single Nucleotide; Software
TL;DR: The microbiome regression-based kernel association test (MiRKAT), which directly regresses the outcome on the microbiome profiles via the semi-parametric kernel machine regression framework, is proposed and applied to real microbiome datasets to show that microbial communities are associated with smoking and with fecal protease levels after confounders are controlled for. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Stability of Caribbean coral communities quantified by long-term monitoring and autoregression models

ECOLOGY, 96(7), 1812–1822.

author keywords: autoregression; coral reefs; global climate change; hurricanes; monitoring; seawater temperature; time-series model; U; S; Virgin Islands
MeSH headings : Animals; Anthozoa / physiology; Caribbean Region; Coral Reefs; Environmental Monitoring / methods; Models, Biological; Time Factors
TL;DR: Analyzing the stability of coral reefs at three habitats at different depths along the south shore of St. John, U.S. Virgin Islands, using multivariate autoregression (MAR) models and two decades of monitoring data sharpen understanding of recent changes, provide a more detailed understanding of how these habitats may change in future environments, and illustrate how MAR models can be used to assess stability of communities founded upon long-lived species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science; OpenAlex)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Seasonal prediction of landfalling hurricanes along Eastern Seaboard of the United States

INTERNATIONAL JOURNAL OF CLIMATOLOGY, 35(9), 2647–2653.

By: T. Yan*, L. Pietrafesa*, D. Dickey n, P. Gayes* & S. Bao*

author keywords: North Atlantic hurricanes; landfall; ACE; ENSO; AMM; AMO; Sahel rainfall; North Atlantic SST; Eastern Seaboard of the US
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Roles of Solvent Accessibility and Gene Expression in Modeling Protein Sequence Evolution

EVOLUTIONARY BIOINFORMATICS, 11.

author keywords: protein evolution; protein structure; gene expression; codon usage; scaled selection coefficient; solvent accessibility
TL;DR: It is come to the biologically plausible conclusion that both RSA and gene expression are related to amino acid frequencies, but, among synonymous codons, the relative probability of a particular codon is more closely related to gene expression than RSA. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Penalized function-on-function regression

COMPUTATIONAL STATISTICS, 30(2), 539–568.

By: A. Ivanescu*, A. Staicu n, F. Scheipl* & S. Greven*

author keywords: Functional data analysis; Functional regression model; Mixed model; Multiple functional predictors; Penalized splines; Tractography data
TL;DR: A general framework for smooth regression of a functional response on one or multiple functional predictors is proposed using the mixed model representation of penalized regression, which allows for seamless integration of continuous or categorical covariates and provides approximate confidence intervals as a by-product of the Mixed model inference. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Parametrically guided estimation in nonparametric varying coefficient models with quasi-likelihood

JOURNAL OF NONPARAMETRIC STATISTICS, 27(2), 195–213.

By: C. Davenport n, A. Maity n & Y. Wu n

Contributors: C. Davenport n, A. Maity n & Y. Wu n

author keywords: nonparametric regression; varying coefficient model; generalised linear models; local polynomial smoothing; parametrically guided estimation; 62G08; 62J12
TL;DR: A guided estimation procedure for the nonparametric VCMs is developed and asymptotic properties are established for the guided estimators and a method of bandwidth selection via bias-variance tradeoff is proposed. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2015 journal article

OPTIMAL DESIGN FOR PARAMETER ESTIMATION IN EEG PROBLEMS IN A 3D MULTILAYERED DOMAIN

MATHEMATICAL BIOSCIENCES AND ENGINEERING, 12(4), 739–760.

By: H. Banks n, D. Rubio, N. Saintier & M. Troparevsky n

author keywords: Electromagnetic inverse problems; optimal design in 3D EEG analysis; parameter estimation; asymptotic error analysis
MeSH headings : Algorithms; Animals; Brain / physiology; Brain Mapping / methods; Computer Simulation; Diagnosis, Computer-Assisted / methods; Electroencephalography / methods; Humans; Models, Neurological; Models, Statistical; Pattern Recognition, Automated / methods; Reproducibility of Results; Sensitivity and Specificity
TL;DR: This work considers an electromagnetic interrogation problem, specifically one arising in an electroencephalography (EEG) problem, of finding optimal number and locations for sensors for source identification in a 3D unit sphere from data on its boundary. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Multiple window discrete scan statistic for higher-order Markovian sequences

JOURNAL OF APPLIED STATISTICS, 42(8), 1690–1705.

By: D. Coleman n, D. Martin n & B. Reich n

author keywords: variable windows; p-values; one-dimensional scan statistics; 60E05; 60J22
TL;DR: This work gives an efficient method to compute the exact distribution of multiple window discrete scan statistics for higher-order, multi-state Markovian sequences and defines a Markov chain to efficiently keep track of probabilities needed to compute p-values for the statistic. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Multilevel quantile function modeling with application to birth outcomes

BIOMETRICS, 71(2), 508–519.

author keywords: Birth weight; Discrete; Extremes; Gestational Age; Graphics processing units; Ozone; Quantile
MeSH headings : Air Pollutants / adverse effects; Bayes Theorem; Biometry; Birth Weight; Computer Simulation; Female; Gestational Age; Humans; Infant; Infant Mortality; Infant, Newborn; Infant, Premature; Infant, Small for Gestational Age; Male; Models, Statistical; Ozone / adverse effects; Pregnancy; Regression Analysis; Texas / epidemiology
TL;DR: A semi‐parametric Bayesian quantile approach that models the full quantile function rather than just a few quantile levels and shows that pooling information across gestational age and quantile level substantially reduces MSE of predictor effects. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Maternal Concern about Child Weight in a Study of Weight-Discordant Siblings

PUBLIC HEALTH NURSING, 32(2), 132–142.

author keywords: maternal concern about child weight; obesity; weight-discordant siblings
MeSH headings : Adult; Attitude to Health; Body Height; Body Mass Index; Body Weight; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Male; Mothers / psychology; Mothers / statistics & numerical data; Pediatric Obesity / psychology; Siblings; Waist Circumference
TL;DR: Mothers' concern for their overweight/obese child's weight was greater for sibling pairs who were more discordant in their weight, and mothers tended to underreport children's height and weight. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Identifying Greater Sage-Grouse source and sink habitats for conservation planning in an energy development landscape

ECOLOGICAL APPLICATIONS, 25(4), 968–990.

author keywords: Atlantic Rim Project Area; Centrocercus urophasianus; energy development; fitness; Greater Sage-Grouse; habitat quality; productivity; resource selection functions; source-sink habitats; south-central Wyoming, USA; survival functions; survival modeling
MeSH headings : Animals; Biomarkers; Coal; Conservation of Natural Resources / methods; Ecosystem; Extraction and Processing Industry; Female; Galliformes / physiology; Natural Gas; Wyoming
TL;DR: The results provide evidence that energy development and avoidance of energy infrastructure were probably reducing the amount of source habitat within the ARPA landscape, and a source-sink map provides managers with a means of prioritizing habitats for conservation planning based on source and sink dynamics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Identification of homogeneous and heterogeneous variables in pooled cohort studies

BIOMETRICS, 71(2), 397–403.

author keywords: Adaptive group lasso; Cox proportional hazards model; Heterogeneity; Penalized partial likelihood; Pooled analysis; Structure identification
MeSH headings : Algorithms; Biometry; Cohort Studies; Computer Simulation; Female; Gene Expression; Humans; Likelihood Functions; Models, Statistical; Ovarian Neoplasms / genetics; Proportional Hazards Models; Sample Size
TL;DR: This article considers the pooled cohort studies with time-to-event outcomes and proposes a penalized Cox partial likelihood approach with adaptively weighted composite penalties on variables' homogeneous and heterogeneous effects and shows that the method can characterize the variables as having heterogeneous, homogeneous, or null effects, and estimate non-zero effects. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Ecologists need robust survey designs, sampling and analytical methods

JOURNAL OF APPLIED ECOLOGY, 52(2), 286–290.

By: M. Hayward*, L. Boitani*, N. Burrows*, P. Funston*, K. Karanth*, D. MacKenzie*, K. Pollock n, R. Yarnell*

author keywords: detectability; dingo debate; ecological methods; indices; intraguild interactions; occupancy modelling; predator interactions; robust survey methods; scientific debates
TL;DR: The debate about the role of dingoes Canis dingo in conservation in Australia is used as a case study for a phenomenon that is relevant to all applied ecologists, where conflicting results have been published in high-quality journals and yet the problems with the methods used have led to significant controversy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Carbon nanotube sheet electrodes for anisotropic actuation of dielectric elastomers

CARBON, 89, 113–120.

By: E. Cakmak n, X. Fang n, O. Yildiz n, P. Bradford n & T. Ghosh n

UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Bayesian structure learning in graphical models

Journal of Multivariate Analysis, 136, 147–162.

author keywords: Graphical lasso; Graphical models; Laplace approximation; Posterior convergence; Precision matrix
TL;DR: This paper considers the problem of estimating a sparse precision matrix of a multivariate Gaussian distribution, where the dimension p may be large, and proposes a fast computational method for approximating the posterior probabilities of various graphs using the Laplace approximation approach. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: August 6, 2018

2015 journal article

Accuracy of SNPs to predict risk of HLA alleles associated with drug-induced hypersensitivity events across racial groups

PHARMACOGENOMICS, 16(8), 817–824.

By: Y. He*, J. Hoskins, S. Clark, N. Campbell, K. Wagner, A. Motsinger-Reif n, H. McLeod*

author keywords: drug-induced hypersensitivity; HLA; human leukocyte antigen; pharmacogenetics; pharmacogenomics; risk mitigation
MeSH headings : Black or African American / genetics; Alleles; Asian People / genetics; Drug Hypersensitivity / genetics; Drug Hypersensitivity / pathology; Genotype; HLA-B Antigens / genetics; HLA-DQ alpha-Chains / genetics; Hispanic or Latino / genetics; Humans; Polymorphism, Single Nucleotide / genetics; White People
TL;DR: This study demonstrates the utility of SNP tagging as a 'real time' approach to predict or exclude the presence of specific HLA alleles of known importance to HSR across diverse ethnic groups. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

A penalized likelihood approach for investigating gene-drug interactions in pharmacogenetic studies

BIOMETRICS, 71(2), 529–537.

author keywords: Association analysis; Haplotype; Individualized medicine; Multiple comparisons; Penalized regression; Pharmacogenetics
MeSH headings : Antineoplastic Agents / adverse effects; Biometry; Computer Simulation; Female; Genes, bcl-2; Haplotypes; Humans; Likelihood Functions; Models, Statistical; Ovarian Neoplasms / drug therapy; Ovarian Neoplasms / genetics; Pharmacogenetics / statistics & numerical data; Regression Analysis
TL;DR: This work proposes a penalized likelihood approach that is able to overcome the drawbacks of the standard approach and yield the desired personalized output and demonstrates the utility of the method by applying it to the Scottish Randomized Trial in Ovarian Cancer. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

A marginal cure rate proportional hazards model for spatial survival data

JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS, 64(4), 673–691.

author keywords: Bayesian hierarchical modelling; Cure rate; Dental data; Extreme value analysis; Frailty; Positive stable; Tooth loss
TL;DR: This model permits predictions that account for the survival status of nearby teeth and simultaneously preserves the proportional hazards relationship marginally over the random effects for the susceptible teeth, allowing for interpretable estimates of the effects of risk factors on tooth loss. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2015 journal article

Variability of Intra-event Statistics for Multiple Fecal Indicator Bacteria in Urban Stormwater

WATER RESOURCES MANAGEMENT, 29(10), 3635–3649.

author keywords: Intra-event; E. coli; Enterococci; Fecal coliform; Urban stormwater; Variability
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Toxicity testing in the 21st century beyond environmental chemicals

Altex-Alternatives to Animal Experimentation, 32(3), 171–181.

By: C. Rovida, S. Asakura, M. Daneshian, H. Hofman-Huether, M. Leist, L. Meunier, D. Reif, A. Rossi ...

Source: NC State University Libraries
Added: August 6, 2018

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