Works Published in 2005

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Displaying works 21 - 40 of 219 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2005 journal article

Label-Free Electronic Detection of Thrombin in Blood Serum by Using an Aptamer-Based Sensor

Angewandte Chemie International Edition, 44(34), 5456–5459.

By: Y. Xiao*, A. Lubin*, A. Heeger* & K. Plaxco*

author keywords: aptamers; biosensors; DNA structures; electron transfer; thrombin
MeSH headings : Aptamers, Nucleotide / chemistry; Biosensing Techniques / instrumentation; Biosensing Techniques / methods; Electrochemistry; Humans; Models, Biological; Sensitivity and Specificity; Thrombin / analysis
Sources: Crossref, NC State University Libraries
Added: August 3, 2021

2005 journal article

Optical and Electrochemical Detection of NADH and of NAD+-Dependent Biocatalyzed Processes by the Catalytic Deposition of Copper on Gold Nanoparticles

Small, 1(2), 213–216.

By: B. Shlyahovsky*, E. Katz*, Y. Xiao*, V. Pavlov* & I. Willner*

author keywords: copper; enzymes; gold; nanoparticles; sensors
MeSH headings : Biosensing Techniques; Catalysis; Copper / chemistry; Electrochemistry / methods; Electrodes; Gold / chemistry; Metal Nanoparticles / chemistry; Microscopy, Electron, Scanning; NAD / chemistry; Nanotechnology / methods; Propylamines; Silanes / chemistry; Surface Properties; Temperature
Sources: Crossref, NC State University Libraries
Added: July 11, 2021

2005 journal article

Inhibition of the Acetycholine Esterase-Stimulated Growth of Au Nanoparticles:  Nanotechnology-Based Sensing of Nerve Gases

Nano Letters, 5(4), 649–653.

By: V. Pavlov*, Y. Xiao* & I. Willner*

MeSH headings : Acetylcholinesterase / chemistry; Acetylcholinesterase / drug effects; Biosensing Techniques; Chemical Warfare Agents / analysis; Cholinesterase Inhibitors / pharmacology; Gold / chemistry; Nanostructures / chemistry; Nanotechnology / methods; Oxidation-Reduction; Paraoxon / pharmacology
TL;DR: The catalytic growth of the Au NPs is inhibited by 1,5-bis(4-allyldimethylammoniumphenyl)pentane-3-one dibromide or by diethyl p-nitrophenyl phosphate (paraoxon; 4), thus enabling a colorimetric test for AChE inhibitors. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 11, 2021

2005 journal article

An OsII-Bisbipyridine-4-Picolinic Acid Complex Mediates the Biocatalytic Growth of Au Nanoparticles: Optical Detection of Glucose and Acetylcholine Esterase Inhibition

Chemistry - A European Journal, 11(9), 2698–2704.

By: Y. Xiao*, V. Pavlov*, B. Shlyahovsky* & I. Willner*

author keywords: enzymes; gold; inhibitors; nanotechnology; sensors
MeSH headings : 2,2'-Dipyridyl / chemistry; Catalysis; Cholinesterase Inhibitors / analysis; Cholinesterase Inhibitors / chemistry; Glucose / analysis; Gold / chemistry; Nanostructures / chemistry; Organometallic Compounds / chemistry; Osmium / chemistry; Picolinic Acids / chemistry; Spectrophotometry, Ultraviolet
TL;DR: The complex Os(II)-bisbipyridine-4-picolinic acid, [Os(bpy)(2)PyCO(2)H](2+) mediates the biocatalyzed growth of Au nanoparticles, Au NPs, and enables the spectroscopic assay of bioc atalyzed transformations and enzyme inhibition by following the Au NP plasmon absorbance. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 11, 2021

2005 journal article

A Reagentless Signal-On Architecture for Electronic, Aptamer-Based Sensors via Target-Induced Strand Displacement

Journal of the American Chemical Society, 127(51), 17990–17991.

By: Y. Xiao*, B. Piorek*, K. Plaxco* & A. Heeger*

MeSH headings : Aptamers, Nucleotide / chemistry; Biosensing Techniques / methods; DNA / chemistry; Electrochemistry; Gold / chemistry; Thrombin / chemistry
TL;DR: Thrombin binding stabilizes the alternative G-quadruplex conformation of the aptamer, liberating the methylene blue (MB)-tagged oligonucleotide to produce a flexible, single-stranded DNA element. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 11, 2021

2005 conference paper

Suppression of chemical phase separation in high-k zirconium an hafnium nitro-silicate and alumino-silicate alloys for CMOS applications

Proceedings of 35th European Solid-State Device Research Conference, 2005. ESSDERC 2005. Presented at the Proceedings of 35th European Solid-State Device Research Conference, 2005. ESSDERC 2005.

By: G. Lucovsky n, J. Phillips* & J. Whitten n

Event: Proceedings of 35th European Solid-State Device Research Conference, 2005. ESSDERC 2005.

Sources: Crossref, NC State University Libraries
Added: May 11, 2021

2005 journal article

Near Edge XRay Absorption Spectroscopy a Novel Approach for Determining Conduction Band Edge States in Transition Metal Oxide Gate Dielectrics

Physica Scripta, 335.

By: G. Lucovsky n, Y. Zhang n, J. Whitten n, D. Schlom* & J. Freeouf*

Sources: Crossref, NC State University Libraries
Added: May 10, 2021

2005 journal article

Increased levels of 4-hydroxynonenal and acrolein, neurotoxic markers of lipid peroxidation, in the brain in Mild Cognitive Impairment and early Alzheimer's disease.

Neurobiology of Aging, 8.

By: T. Williams*, B. Lynn*, W. Markesbery* & M. Lovell*

author keywords: early Alzheimer's disease; Mild Cognitive Impairment; lipid peroxidation; oxidative stress; Alzheimer's disease
MeSH headings : Acrolein / metabolism; Aged, 80 and over; Aldehydes / metabolism; Alzheimer Disease / metabolism; Biomarkers / metabolism; Brain / metabolism; Cognition Disorders / metabolism; Female; Humans; Lipid Peroxidation; Male; Tissue Distribution
TL;DR: The results suggest that lipid peroxidation occurs early in the pathogenesis of AD, and levels of HNE in HPG and SMTG and a significant increase in acrolein in all three brain regions studied. (via Semantic Scholar)
Source: ORCID
Added: April 8, 2021

2005 journal article

Analysis of derivatized biogenic aldehydes by LC tandem mass spectrometry.

Analytical Chemistry, 5(10), 3383–3389.

Contributors: T. Williams*, M. Lovell* & B. Lynn*

MeSH headings : Acrolein / analysis; Acrolein / metabolism; Aldehydes / analysis; Aldehydes / metabolism; Alzheimer Disease / etiology; Alzheimer Disease / pathology; Biomarkers / analysis; Biomarkers / metabolism; Chromatography, Liquid / methods; Humans; Lipid Peroxidation; Tandem Mass Spectrometry / methods; Tissue Distribution
TL;DR: The LC-MS/MS methodology developed here will be used in subsequent studies to determine aldehyde concentrations for comparing age-matched controls to AD tissues from human subjects. (via Semantic Scholar)
Source: ORCID
Added: April 8, 2021

2005 journal article

Reproducibility of Retention Time using a Splitless nanoLC Coupled to an ESI-FTICR Mass Spectrometer

Journal of Biomolecular Techniques, 16, 4, 414–422.

By: D. Muddiman, C. Mason & K. Johnson

Source: NC State University Libraries
Added: March 17, 2021

2005 journal article

A Reinterpretation of the Mechanism of the Simplest Reaction at an sp3-Hybridized Carbon Atom:  H + CD4 → CD3 + HD

Journal of the American Chemical Society, 127(34), 11898–11899.

TL;DR: It is found that bent H-D-C transition state geometries play an important role in the dynamics of the H + CD4 reaction and a simple model that relates the scattering angle impact parameter and cone of acceptance accounts well for the overall reaction dynamics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 20, 2021

2005 journal article

Effects of Bending Excitation on the Reaction of Chlorine Atoms with Methane

Angewandte Chemie International Edition, 44(16), 2382–2385.

author keywords: gas-phase reactions; kinetics; molecular dynamics; reaction mechanisms; vibrational spectroscopy
TL;DR: Direct measurements of the effects of bend-excitation on an atom + polyatom reaction system under single collision conditions are presented and it is confirmed that one quantum of antisymmetric stretch excitation enhances the reaction by a factor of approximately 30. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 16, 2021

2005 journal article

Nucleic Acid Analysis by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry at the Beginning of the Twenty-First Century

Current Pharmaceutical Design, 11(20), 2593–2613.

By: J. Frahm & D. Muddiman*

author keywords: FT-ICR; Fourier transform ion cyclotron resonance; mass spectrometry; DNA; RNA; PNA
MeSH headings : Nucleic Acids / analysis; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Electrospray Ionization / trends; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / trends; Spectroscopy, Fourier Transform Infrared / methods; Spectroscopy, Fourier Transform Infrared / trends; Spectrum Analysis / methods; Spectrum Analysis / trends; Technology, Pharmaceutical / instrumentation; Technology, Pharmaceutical / methods; Technology, Pharmaceutical / trends
TL;DR: A diverse range of studies including fundamental studies of nucleic acid properties, improvements in sample clean up and preparation, better methods to obtain higher mass measurement accuracy, analysis of noncovalent complexes, tandem mass spectrometry, and characterization of peptide nucleic acids are presented. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 12, 2021

2005 journal article

Primary Trabecular Meshwork Cells Incubated in Human Aqueous Humor Differ from Cells Incubated in Serum Supplements

Investigative Opthalmology & Visual Science, 46(8), 2848.

By: M. Fautsch, K. Howell, A. Vrabel, M. Charlesworth*, D. Muddiman* & D. Johnson

MeSH headings : Adult; Aged; Aged, 80 and over; Aqueous Humor / physiology; Ascorbic Acid / metabolism; Ascorbic Acid / pharmacology; Blotting, Western; Cell Culture Techniques; Cell Proliferation; Culture Media; Cytoskeletal Proteins / metabolism; Dexamethasone / pharmacology; Electrophoresis, Gel, Two-Dimensional; Eye Proteins / metabolism; Female; Glycoproteins / metabolism; Humans; Infant; Male; Middle Aged; Serum; Tissue Inhibitor of Metalloproteinase-1 / metabolism; Trabecular Meshwork / cytology; Trabecular Meshwork / drug effects; Trabecular Meshwork / metabolism
TL;DR: Addition of human aqueous humor rather than FBS to trabecular monolayer cell cultures triggers significant changes in cellular and molecular characteristics. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 12, 2021

2005 journal article

Poly[nickel(II)-di-μ-4,4′-bipyridyl-κ4N:N′-μ-dichromato-κ2O:O′] and poly[copper(II)-di-μ-4,4'-bipyridyl-κ4N:N′-μ-dichromato-κ2O:O′]

Acta Crystallographica Section C Crystal Structure Communications, 61(4), m165–m168.

UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: February 6, 2021

2005 journal article

Loaded dopamine is preferentially stored in the halo portion of PC12 cell dense core vesicles

Journal of Neurochemistry, 93(5), 1122–1131.

By: L. Sombers*, M. Maxson* & A. Ewing*

author keywords: amperometry; dense core vesicles; exocytosis; PC12 cells; vesicular volume
MeSH headings : Animals; Catecholamines / metabolism; Dopamine / pharmacokinetics; Dopamine Agents / pharmacology; Electrochemistry; Extracellular Fluid / metabolism; Levodopa / pharmacology; Models, Theoretical; Osmolar Concentration; Osmosis; PC12 Cells / metabolism; Rats; Secretory Vesicles / metabolism; Tissue Distribution
TL;DR: Evidence is presented indicating that upon treatment with L‐DOPA the majority of the dopamine loaded into these vesicles is preferentially compartmentalized into the halo portion of the vesicle, suggesting that newly loaded dopamine is located in the h Halo of thevesicle. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 6, 2021

2005 journal article

Correlation between Vesicle Quantal Size and Fusion Pore Release in Chromaffin Cell Exocytosis

Biophysical Journal, 88(6), 4411–4420.

By: C. Amatore*, S. Arbault*, I. Bonifas*, Y. Bouret*, M. Erard*, A. Ewing*, L. Sombers*

MeSH headings : Animals; Biophysical Phenomena; Biophysics; Catecholamines / metabolism; Cattle; Chromaffin Cells / metabolism; Chromaffin Cells / physiology; Electrophysiology; Exocytosis / physiology; In Vitro Techniques; Kinetics; Membrane Fusion / physiology; Models, Biological; Secretory Vesicles / physiology
TL;DR: It is hypothesized that in chromaffin cells, the expanding core is a controlling factor in opening the fusion pore, that prefusion of two smaller vesicles leads to excess membrane, and that this slows pore expansion leading to an increased observation of events with a foot. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 5, 2021

2005 book

Amorphous materials engineering: Designing structure in liquid and glassy metal-halide networks

In Ceramic Transactions (Vol. 170, pp. 57–67). http://www.scopus.com/inward/record.url?eid=2-s2.0-23744502926&partnerID=MN8TOARS

By: J. Martin

Contributors: J. Martin

Source: ORCID
Added: January 26, 2021

2005 journal article

Quantitative Protein Expression Analysis Of CLL B Cells from Mutated and Unmutated IgVHSubgroups Using Acid-Cleavable Isotope-Coded Affinity Tag Reagents

Journal of Proteome Research, 4(4), 1310–1317.

By: D. Barnidge*, D. Jelinek*, D. Muddiman* & N. Kay*

author keywords: CLL; B cell; quantitative comparison; clCAT; UM-CLL; M-CLL; linear ion trap mass spectrometer
MeSH headings : B-Lymphocytes / chemistry; B-Lymphocytes / immunology; Cell Fractionation; Genes, Immunoglobulin; Humans; Immunoglobulin Heavy Chains / genetics; Immunoglobulin Heavy Chains / immunology; Immunoglobulin Variable Region / genetics; Immunoglobulin Variable Region / immunology; Isotope Labeling / methods; Leukemia, Lymphocytic, Chronic, B-Cell / immunology; Mass Spectrometry / methods; Mutation; Proteome / analysis
TL;DR: Stable isotope labeling and mass spectrometry can complement 2D gel electrophoresis and gene microarray technologies for identifying putative and perhaps unique prognostic markers in CLL. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 18, 2021

2005 journal article

Property and Morphology Development in Nanocomposite Thermoplastic Elastomer Gels

Langmuir, 21(7), 3106–3115.

By: G. van Maanen n, S. Seeley n, M. Capracotta n, S. White n, R. Bukovnik n, J. Hartmann n, J. Martin n, R. Spontak n

Contributors: G. Van Maanen n, S. Seeley n, M. Capracotta n, S. White n, R. Bukovnik n, J. Hartmann n, J. Martin n, R. Spontak n

TL;DR: This work investigates the effect of several network-forming nanoscale modifiers-two different silica nanoparticles, three different nanoclays, and a multiwalled carbon nanotube-on the property and morphology development of a TPEG prepared from a microphase-ordered poly(styrene-b-(ethylene-co-butylene)-b-styrene) (SEBS) triblock copolymer imbibed with an EB-compatible aliphatic mineral oil. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, ORCID, NC State University Libraries
Added: December 31, 2020

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