Works Published in 2010
Displaying works 201 - 220 of 675 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2010 journal article
Parvalbumin Deficiency and GABAergic Dysfunction in Mice Lacking PGC-1α
Journal of Neuroscience, 30(21), 7227–7235.
MeSH headings : Analysis of Variance; Animals; Animals, Newborn; Biophysics; Cells, Cultured; DNA-Binding Proteins / metabolism; Electric Stimulation / methods; GTP Phosphohydrolases / metabolism; Gene Expression Regulation, Developmental / genetics; Glutamate Decarboxylase / metabolism; Heart; High Mobility Group Proteins / metabolism; Hippocampus / cytology; Humans; Inhibitory Postsynaptic Potentials / drug effects; Inhibitory Postsynaptic Potentials / genetics; Interneurons / metabolism; Long-Term Potentiation / drug effects; Long-Term Potentiation / genetics; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium / metabolism; Parvalbumins / deficiency; Patch-Clamp Techniques / methods; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; RNA, Messenger / metabolism; Shaw Potassium Channels / metabolism; Trans-Activators / deficiency; Trans-Activators / metabolism; Transcription Factors / metabolism; Transfection / methods; gamma-Aminobutyric Acid / metabolism
TL;DR:
Findings indicate that PGC-1α is a novel regulator of interneuron gene expression and function and a potential therapeutic target for neurological disorders associated with Interneuron dysfunction.
(via Semantic Scholar)
www.jneurosci.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: September 9, 2019
2010 journal article
Model or meal? Farm animal populations as models for infectious diseases of humans
Nature Reviews Microbiology, 8(2), 139–148.
Contributors: C. Lanzas* , P. Ayscue*, R. Ivanek * & Y. Gröhn *
MeSH headings : Animals; Animals, Domestic / microbiology; Animals, Domestic / virology; Communicable Diseases / microbiology; Communicable Diseases / transmission; Communicable Diseases / virology; Disease Models, Animal; Host-Pathogen Interactions; Humans; Models, Biological; Population
TL;DR:
Farm animal populations can provide empirical models to study infectious diseases at the population level because they have been widely used as models at the organism level and are less appropriate for addressing issues at thepopulation level.
(via Semantic Scholar)
Source: ORCID
Added: September 9, 2019
2010 journal article
Transmission dynamics of a multidrug-resistant salmonella typhimurium outbreak in a dairy farm
Foodborne Pathogens and Disease, 7(4), 467–474.
Contributors: C. Lanzas* , L. Warnick *, K. James*, E. Wright *, M. Wiedmann * & Y. Gröhn *
MeSH headings : Animals; Anti-Infective Agents / pharmacology; Bacterial Shedding; Cattle; Cattle Diseases / epidemiology; Cattle Diseases / microbiology; Cattle Diseases / transmission; Computer Simulation; Dairying / methods; Disease Outbreaks / veterinary; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field / veterinary; Feces / microbiology; Longitudinal Studies; Microbial Sensitivity Tests / veterinary; Models, Statistical; Salmonella Infections, Animal / epidemiology; Salmonella Infections, Animal / microbiology; Salmonella Infections, Animal / transmission; Salmonella typhimurium / classification; Salmonella typhimurium / drug effects; Salmonella typhimurium / isolation & purification; Salmonella typhimurium / pathogenicity; Serologic Tests / veterinary; Serotyping / veterinary; Time Factors
TL;DR:
Simulations of the transmission model indicated that salmonellosis outbreaks with few clinical cases were likely due to the extinction of the pathogen in the premises in the early phase of the outbreaks, and small population size and group structure within the farm decrease the on-farm persistence of the Pathogen.
(via Semantic Scholar)
Source: ORCID
Added: September 9, 2019
2010 journal article
Developing an engineered antimicrobial/prophylactic system using electrically activated bactericidal metals
Journal of Materials Science: Materials in Medicine, 21(7), 2103–2114.
Contributors: T. Fuller, R. Wysk, C. Charumani*, M. Kennett*, W. Sebastiennelli, R. Abrahams *, R. Shirwaiker* , R. Voigt, P. Royer
MeSH headings : Anti-Bacterial Agents / pharmacology; Anti-Infective Agents / pharmacology; Electricity; Electrodes; Gels; Humans; Metals / pharmacology; Silver / pharmacology; Silver Compounds / pharmacology
TL;DR:
A surface treatment based on ionic emission to create an antibiotic environment that can significantly reduce RHD associated infections is proposed.
(via Semantic Scholar)
Source: ORCID
Added: September 6, 2019
2010 conference paper
Design of an electrically activated silver-based antibacterial surface system
IIE Annual Conference and Expo 2010 Proceedings. http://www.scopus.com/inward/record.url?eid=2-s2.0-84901037163&partnerID=MN8TOARS
Contributors: R. Shirwaiker , R. Voigt & R. Wysk
Source: ORCID
Added: September 6, 2019
2010 journal article
Mucosal epithelial barrier repair to maintain pig health
Livestock Science, 133(1-3), 194–199.
Contributors: A. Blikslager n
author keywords: Restitution; Tight junction; Villus contraction; Epithelium; Sepsis
TL;DR:
Mucosal barrier function is critical to prevent translocation of microorganisms and their toxins and the prominent contribution of the paracellular space to measures of barrier function such as transepithelial electrical resistance is highlighted.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: September 3, 2019
2010 journal article
Effect of firocoxib or flunixin meglumine on recovery of ischemic-injured equine jejunum | Wirkung von firocoxib oder flunixin auf die regeneration des ischämisch geschädigtem jejunum beim pferd
Pferdeheilkunde, 26(1), 100–101. http://www.scopus.com/inward/record.url?eid=2-s2.0-77749270496&partnerID=MN8TOARS
Contributors: V. Cook, C. Meyer, N. Campbell & A. Blikslager
Source: ORCID
Added: September 3, 2019
2010 journal article
A surgical tendonitis model in horses: Technique, clinical, ultrasonographic and histological characterisation
Veterinary and Comparative Orthopaedics and Traumatology, 23(4), 231–239.
Contributors: M. Schramme, S. Hunter, N. Campbell, A. Blikslager* & R. Smith
author keywords: Surgical model; tendonitis; horse; superficial digital flexor tendon
MeSH headings : Anesthesia, General / veterinary; Animals; Euthanasia, Animal; Follow-Up Studies; Forelimb / surgery; Horse Diseases / diagnostic imaging; Horse Diseases / pathology; Horse Diseases / surgery; Horses; Postoperative Care / veterinary; Tendinopathy / diagnostic imaging; Tendinopathy / pathology; Tendinopathy / surgery; Tendinopathy / veterinary; Time Factors; Treatment Outcome; Ultrasonography / veterinary
TL;DR:
The reported surgical technique resulted in core lesions that were consistent in size and location, were readily evaluated with ultrasonography, and showed similarities with the ultrasonographic and histological progression of naturally occurring tendonitis lesions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: September 3, 2019
2010 book
Alimentary diseases
In Diagnostic Techniques in Equine Medicine: Second Edition (pp. 28–72). http://www.scopus.com/inward/record.url?eid=2-s2.0-84905885831&partnerID=MN8TOARS
Contributors: A. Blikslager
Source: ORCID
Added: September 3, 2019
2010 journal article
A systematic review of the evidence of reduced allergenicity and clinical benefit of food hydrolysates in dogs with cutaneous adverse food reactions
Veterinary Dermatology, 21(1), 31–40.
Contributors: T. Olivry n & P. Bizikova n
MeSH headings : Animal Feed / analysis; Animals; Dermatitis / veterinary; Dog Diseases / prevention & control; Dogs; Food Handling; Food Hypersensitivity / veterinary
TL;DR:
A limited number of studies undertaken point to reduced - but not eliminated - immunological and clinical allergenicity of hydrolysate-based commercial diets, which are probably best used in dogs suspected not to be hypersensitive to their individual components.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: August 29, 2019
2010 journal article
New diagnostic criteria for canine atopic dermatitis
Veterinary Dermatology, 21(1), 123–126.
Contributors: T. Olivry n
MeSH headings : Animals; Dermatitis, Atopic / diagnosis; Dermatitis, Atopic / pathology; Dermatitis, Atopic / veterinary; Dog Diseases / diagnosis; Dogs; Humans; International Cooperation; Practice Guidelines as Topic; Predictive Value of Tests; Sensitivity and Specificity; Veterinary Medicine / standards
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: August 29, 2019
2010 journal article
Canine and feline pemphigus foliaceus: Improving your chances of a successful outcome
Veterinary Medicine, 105(1), 18–30. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955910081&partnerID=MN8TOARS
Contributors: K. Tater & T. Olivry
Source: ORCID
Added: August 29, 2019
2010 journal article
A new technique for emergency venous access
EZ-IO: Procedures Pro: Clinicians Breif.
Source: NC State University Libraries
Added: August 18, 2019
2010 journal article
Gene-drive into insect populations with age and spatial structure: a theoretical assessment
Evolutionary Applications, 4(3), 415–428.
author keywords: age and spatial structure; engineered underdominance; gene drive; release threshold; theoretical assessment
TL;DR:
This study demonstrates that to determine the best method of spatial release, and the total number of engineered insects that must be released, it is important to take into account the age and sex of the released insects and spatial structure of the population.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: July 28, 2019
2010 journal article
Heart to Heart
Circulation, 121(18), 1981–1984.
author keywords: Editorials; heart; regenerative medicine; stem cells
MeSH headings : Bone Marrow Cells / cytology; Hematopoietic Stem Cell Transplantation; Humans; Myocardial Ischemia / therapy; Myocytes, Cardiac / cytology; Regeneration
TL;DR:
In conclusion, injection of autologous BMCs as adjunctive treatment for convalescent myocardial infarction has proven to be remarkably safe and the overall efficacy is modest, but certain subgroups do experience clinically meaningful increments in ejection fraction.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: July 28, 2019
2010 journal article
Cardiospheres Recapitulate a Niche-Like Microenvironment Rich in Stemness and Cell-Matrix Interactions, Rationalizing Their Enhanced Functional Potency for Myocardial Repair
STEM CELLS, 28(11), 2088–2098.
author keywords: Cardiac stem cells; Stem cell niche; Extracellular-matrix molecules; Adhesion molecule
MeSH headings : Animals; Blotting, Western; Cells, Cultured; Echocardiography; Extracellular Matrix / metabolism; Flow Cytometry; Histone Deacetylase 2 / metabolism; Humans; Insulin-Like Growth Factor I / metabolism; Integrin alpha2 / metabolism; Laminin / metabolism; Mice; Mice, SCID; Myocardial Infarction / metabolism; Myocardial Infarction / therapy; Myocardium / cytology; Myocardium / metabolism; Oxidative Stress / physiology; Polymerase Chain Reaction; Stem Cell Transplantation; Stem Cells / cytology; Stem Cells / metabolism; Telomerase / metabolism
TL;DR:
Growth of cardiac‐derived cells as cardiospheres mimics stem cell niche properties with enhanced “stemness” and expression of ECM and adhesion molecules underlie an increase in cell survival and more potent augmentation of global function following implantation into the infarcted heart.
(via Semantic Scholar)
Source: Crossref
Added: July 28, 2019
2010 journal article
Exploring cellular adhesion and differentiation in a micro-/nano-hybrid polymer scaffold
Biotechnology Progress, 26(3), 838–846.
author keywords: tissue engineering; scaffold; stem cell; micro-/nano-fabrication; adhesion
MeSH headings : Cell Adhesion; Cell Differentiation; Cells, Cultured; Fibroblasts / cytology; Humans; Materials Testing; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Nanostructures / chemistry; Nanostructures / ultrastructure; Neurons / cytology; Porosity; Shear Strength; Stem Cells / cytology; Tissue Engineering / methods; Tissue Scaffolds / chemistry
TL;DR:
This study represents a systematic comparison of cellular activities on micro‐only, nano‐only and micro/nano combined scaffolds, and demonstrates the unique advantages of the later.
(via Semantic Scholar)
Source: Crossref
Added: July 28, 2019
2010 journal article
Dedifferentiation and Proliferation of Mammalian Cardiomyocytes
PLoS ONE, 5(9), e12559.
Ed(s): A. Kowaltowski
MeSH headings : Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; GATA4 Transcription Factor / genetics; GATA4 Transcription Factor / metabolism; Homeobox Protein Nkx-2.5; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Male; Mice; Mice, Transgenic; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Rats; Rats, Inbred WKY; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR:
Contradicting the prevailing view that they are terminally-differentiated, postnatal mammalian cardiomyocytes are instead capable of substantial plasticity.
(via Semantic Scholar)
Source: Crossref
Added: July 28, 2019
2010 journal article
Expansion of human cardiac stem cells in physiological oxygen improves cell production efficiency and potency for myocardial repair
Cardiovascular Research, 89(1), 157–165.
author keywords: Physiological oxygen; Ex vivo expansion; Cardiac stem cells
MeSH headings : Adult; Adult Stem Cells / cytology; Adult Stem Cells / physiology; Adult Stem Cells / transplantation; Aneuploidy; Animals; Cell Differentiation; Cell Proliferation; Cellular Senescence; DNA Damage; Humans; In Vitro Techniques; Male; Mice; Mice, SCID; Muscle Development / physiology; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocardium / cytology; Oxidative Stress; Oxygen / physiology; Reactive Oxygen Species / metabolism; Regeneration / physiology; Transplantation, Heterologous
TL;DR:
The expansion of human adult cardiac stem cells in low oxygen increased cell yield, and the resulting cells were superior by various key in vitro and in vivo metrics of cell quality.
(via Semantic Scholar)
Source: Crossref
Added: July 28, 2019
2010 journal article
Magnetic Targeting Enhances Engraftment and Functional Benefit of Iron-Labeled Cardiosphere-Derived Cells in Myocardial Infarction
Circulation Research, 106(10), 1570–1581.
author keywords: cardiac progenitor cells; cell transplantation; myocardial infarction; targeted cell delivery
MeSH headings : Animals; Cell Differentiation; Cell Survival; Echocardiography; Female; Genes, sry; In Situ Nick-End Labeling; Inflammation / physiopathology; Iron; Male; Mesenchymal Stem Cell Transplantation / methods; Myocardial Infarction / diagnostic imaging; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Myocardial Infarction / surgery; Polymerase Chain Reaction; Rats; Rats, Inbred WKY
Source: Crossref
Added: July 28, 2019
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