Cherilyn L Heggen-Peay

Works (7)

Updated: July 5th, 2023 16:03

2002 journal article

Interactions of poult enteritis and mortality syndrome-associated reovirus with various cell types in vitro

POULTRY SCIENCE, 81(11), 1661–1667.

By: C. Heggen-Peay n, M. Cheema n, R. Ali n, K. Schat n & M. Qureshi n

author keywords: poult enteritis and mortality syndrome; reovirus; replication; immune response
MeSH headings : Animals; Antigens, Viral / analysis; B-Lymphocytes / metabolism; B-Lymphocytes / virology; Cell Line; Cells, Cultured; Chickens; Cytopathogenic Effect, Viral; Interleukin-1 / genetics; Interleukin-1 / metabolism; Liver / cytology; Liver / virology; Macrophages / metabolism; Macrophages / virology; Microscopy, Electron / veterinary; Orthoreovirus, Avian / growth & development; Orthoreovirus, Avian / immunology; Orthoreovirus, Avian / pathogenicity; Poult Enteritis Mortality Syndrome / metabolism; Poult Enteritis Mortality Syndrome / virology; Poultry Diseases / metabolism; Poultry Diseases / virology; RNA, Messenger / metabolism; Reoviridae Infections / veterinary; Reoviridae Infections / virology; Specific Pathogen-Free Organisms; T-Lymphocytes / metabolism; T-Lymphocytes / virology; Tumor Cells, Cultured; Turkeys; Virus Replication
TL;DR: It is demonstrated that ARV-CU98 actively infects and replicates in LMH cells, but not in lymphocytes or macrophages, suggesting that the liver may be a target and site of replication of ARV -CU98 in poults experiencing PEMS. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Isolation of a reovirus from poult enteritis and mortality syndrome and its pathogenicity in turkey poults

AVIAN DISEASES, 46(1), 32–47.

By: C. Heggen-Peay n, M. Qureshi n, F. Edens n, B. Sherry*, P. Wakenell, . PH O'Connell, K. Schat*

author keywords: poult enteritis and mortality syndrome; reovirus; turkey; fecal filtrate
TL;DR: It is demonstrated that ARV-CU98 does cause some of the clinical signs in PEMS, including intestinal alterations and significantly lower relative bursa and liver weights. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2001 journal article

Induction of functional defects in macrophages by a poult enteritis and mortality syndrome-associated turkey astrovirus

AVIAN DISEASES, 45(4), 853–861.

By: M. Qureshi n, Y. Saif, C. Heggen-Peay*, F. Edens* & G. Havenstein*

author keywords: turkey astrovirus; poult enteritis and mortality; syndrome; macrophage functions; interleukins; phagocytosis; bacterial killing
TL;DR: The findings of these studies indicated that TAst-OSU challenge induced defects in macrophage effector functions, implying that PEMS-turkey astrovirus can potentially impair the immune response of turkeys, thereby leading to enhanced susceptibility ofTurkeys to secondary, perhaps even fatal, bacterial infections. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Alterations in macrophage-produced cytokines and nitrite associated with poult enteritis and mortality syndrome

AVIAN DISEASES, 44(1), 59–65.

By: C. Heggen n, M. Qureshi*, F. Edens* & H. Barnes*

author keywords: poult enteritis and mortality syndrome; macrophage; turkey; cytokine; nitrite
TL;DR: It is suggested that the enhanced production of proinflammatory cytokine/metabolites by activated macrophages in PEMS poults may be responsible, at least in part, for the physiological intestinal inflammation, gut motility, and anorexia that characterize this disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2000 review

Avian macrophage: effector functions in health and disease

[Review of ]. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 24(2-3), 103–119.

By: M. Qureshi n, C. Heggen & I. Hussain

author keywords: macrophage; macrophage-pathogen interaction; macrophage-environmental interaction; macrophage functions; avian
MeSH headings : Animals; Bird Diseases / immunology; Bird Diseases / microbiology; Bird Diseases / parasitology; Bird Diseases / virology; Macrophages / immunology; Macrophages / microbiology; Macrophages / parasitology; Macrophages / virology
TL;DR: The basic profiles of severalmacrophage effector functions are described and the interaction of macrophages with various pathogens as well as the effect of genetic and environmental factors on macrophage functional modulation is described. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Vanadium stimulates immunological responses of chicks

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 68(1), 61–71.

By: M. Qureshi n, C. Hill n & C. Heggen n

author keywords: vanadium; antibody response; macrophage functions; interleukins; lymphocytes; protein-tyrosinephosphate
MeSH headings : Adjuvants, Immunologic / pharmacology; Animals; Antibody Formation / drug effects; CD4-CD8 Ratio / drug effects; Chickens; Female; Macrophages / drug effects; Macrophages / immunology; Male; Protein Tyrosine Phosphatases / metabolism; Vanadium / pharmacology
TL;DR: Densitometric analysis of lysates of macrophages isolated from control and V-fed chicks for anti-protein-tyrosinephosphate (PTP) bands indicate that dietary V increased PTP. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Alterations in the lymphocytic and mononuclear phagocytic systems of turkey poults associated with exposure to poult enteritis and mortality syndrome

AVIAN DISEASES, 42(4), 711–720.

By: C. Heggen n, M. Qureshi*, F. Edens*, H. Barnes* & G. Havenstein*

author keywords: poult enteritis and mortality syndrome; macrophage; turkey; Escherichia coli; lymphocytes
TL;DR: In conclusion, immune system dysfunction in PEMS is associated with impaired mononuclear phagocytic system function and alterations in lymphocyte populations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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