Jeane Marie Govan

Works (9)

Updated: August 19th, 2023 17:45
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2015 journal article

Optically triggered immune response through photocaged oligonucleotides

TETRAHEDRON LETTERS, 56(23), 3639–3642.

By: J. Govan n, D. Young n, M. Lively* & A. Deiters n

author keywords: Oligonucleotide synthesis; Light-activation; Photocaged nucleotides; Immune response; Toll-like receptors
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Cellular Delivery and Photochemical Activation of Antisense Agents through a Nucleobase Caging Strategy

ACS CHEMICAL BIOLOGY, 8(10), 2272–2282.

By: J. Govan n, R. Uprety n, M. Thomas  n, H. Lusic n, M. Lively* & A. Deiters n

MeSH headings : Base Sequence; Gene Transfer Techniques; HeLa Cells; Humans; Light; Models, Biological; Molecular Structure; Oligonucleotides, Antisense / chemistry; Oligonucleotides, Antisense / genetics; Oligonucleotides, Antisense / metabolism; Polymerase Chain Reaction; tat Gene Products, Human Immunodeficiency Virus / chemistry; tat Gene Products, Human Immunodeficiency Virus / genetics
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Optochemical control of RNA interference in mammalian cells

NUCLEIC ACIDS RESEARCH, 41(22), 10518–10528.

By: J. Govan*, D. Young *, H. Lusic n, Q. Liu  n, M. Lively* & A. Deiters n

Source: Web Of Science
Added: August 6, 2018

2012 journal article

Hydrogen Peroxide Induced Activation of Gene Expression in Mammalian Cells using Boronate Estrone Derivatives

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 51(36), 9066–9070.

By: J. Govan n, A. McIver n, C. Riggsbee n & A. Deiters n

author keywords: biosensors; estrogen receptor; estrone; gene expression; hydrogen peroxide
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Regulation of transcription through light-activation and light-deactivation of triplex-forming oligonucleotides in mammalian cells

ACS Chemical Biology, 7(7), 1247–1256.

By: J. Govan n, R. Uprety n, J. Hemphill n, M. Lively* & A. Deiters n

MeSH headings : DNA / chemistry; DNA / metabolism; HEK293 Cells; Humans; Nucleic Acid Conformation; Oligonucleotides / chemistry; Oligonucleotides / metabolism; Photic Stimulation / methods; Transcription, Genetic / physiology
Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Photochemical Control of DNA Decoy Function Enables Precise Regulation of Nuclear Factor kappa B Activity

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133(33), 13176–13182.

By: J. Govan n, M. Lively* & A. Deiters n

MeSH headings : Alkaline Phosphatase / genetics; Gene Expression Regulation / radiation effects; Light; Methods; NF-kappa B / metabolism; Oligodeoxyribonucleotides / radiation effects; Photochemical Processes; Transcription, Genetic / drug effects
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Stabilization and Photochemical Regulation of Antisense Agents through PEGylation

BIOCONJUGATE CHEMISTRY, 22(10), 2136–2142.

By: J. Govan n, A. McIver n & A. Deiters n

MeSH headings : Animals; DNA, Antisense / chemical synthesis; DNA, Antisense / chemistry; DNA, Antisense / genetics; DNA, Antisense / metabolism; Gene Expression Regulation; HEK293 Cells; Humans; Luminescent Proteins / genetics; Mice; NIH 3T3 Cells; Nucleic Acid Denaturation; Photolysis; Polyethylene Glycols / chemistry; Ribonuclease H / metabolism; Ultraviolet Rays
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Photocaged Morpholino Oligomers for the Light-Regulation of Gene Function in Zebrafish and Xenopus Embryos

Journal of the American Chemical Society, 132(44), 15644–15650.

By: A. Deiters n, R. Garner n, H. Lusic n, J. Govan n, M. Dush n, N. Nascone-Yoder n, J. Yoder n 

MeSH headings : Animals; Cells, Cultured; Embryo, Nonmammalian / metabolism; Gene Expression; Morpholines / chemistry; Oligonucleotides / genetics; Oligonucleotides / metabolism; Ultraviolet Rays; Xenopus laevis / genetics; Xenopus laevis / metabolism; Zebrafish / genetics; Zebrafish / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Photochemical Regulation of Restriction Endonuclease Activity

CHEMBIOCHEM, 10(10), 1612–1616.

By: D. Young n, J. Govan n, M. Lively* & A. Deiters n

author keywords: cage compounds; DNA cleavage; DNA enzymes; photochemistry
MeSH headings : Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Base Sequence; Benzodioxoles / chemistry; DNA / chemistry; DNA / radiation effects; DNA Cleavage; DNA Restriction Enzymes / genetics; DNA Restriction Enzymes / metabolism; Deoxyribonuclease BamHI / genetics; Deoxyribonuclease BamHI / metabolism; Deoxyribonuclease EcoRI / genetics; Deoxyribonuclease EcoRI / metabolism; Deoxyribonucleases, Type II Site-Specific / genetics; Deoxyribonucleases, Type II Site-Specific / metabolism; Substrate Specificity; Thymidine / analogs & derivatives; Thymidine / chemistry; Ultraviolet Rays
Source: Web Of Science
Added: August 6, 2018