Lin Zhang

Works (5)

Updated: August 3rd, 2023 21:15

2019 journal article

EPA and DHA Inhibit Myogenesis and Downregulate the Expression of Muscle-related Genes in C2C12 Myoblasts

Genes, 10(1), 64.

By: J. Zhang *, X. Xu *, Y. Liu *, Y. Liu *, L. Zhang*, J. Odle n , H. Zhu  n, X. Wang *, Y. Liu *, Y. Liu *

author keywords: C2C12; proliferation; differentiation; EPA; DHA
MeSH headings : Animals; Cell Differentiation; Cell Line; Docosahexaenoic Acids / pharmacology; Down-Regulation; Eicosapentaenoic Acid / pharmacology; Insulin-Like Growth Factor II / genetics; Insulin-Like Growth Factor II / metabolism; MAP Kinase Signaling System; Mice; Muscle Development; Myoblasts / cytology; Myoblasts / drug effects; Myoblasts / metabolism; Myoglobin / genetics; Myoglobin / metabolism; Myosin Heavy Chains / genetics; Myosin Heavy Chains / metabolism; Myosin Light Chains / genetics; Myosin Light Chains / metabolism; Troponin / genetics; Troponin / metabolism
topics (OpenAlex): Adipose Tissue and Metabolism; Fatty Acid Research and Health; Muscle metabolism and nutrition
TL;DR: It is suggested that EPA and DHA exerted an inhibitory effect on myoblast proliferation and differentiation and downregulated muscle-related genes expression. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: March 18, 2019

2019 article

Shifts in the Composition and Activities of Denitrifiers Dominate CO2 Stimulation of N2O Emissions

Qiu, Y., Jiang, Y., Guo, L., Zhang, L., Burkey, K. O., Zobel, R. W., … Hu, S. (2019, August 29). Environmental Science & Technology, Vol. 53, pp. 11204–11213.

By: Y. Qiu n, Y. Jiang n, L. Guo  n, L. Zhang*, K. Burkey n, R. Zobel n, S. Reberg-Horton n , H. Shew  n, S. Hu  n

MeSH headings : Carbon Dioxide; Denitrification; Nitrogen; Nitrous Oxide; Soil; Soil Microbiology
topics (OpenAlex): Atmospheric chemistry and aerosols; Catalytic Processes in Materials Science; Plant responses to elevated CO2
TL;DR: The results suggest that effective management of N sources may mitigate N2O emissions by negating eCO2-stimulation of soil denitrifying microbes and their activities. (via Semantic Scholar)
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2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 28, 2019

2011 article

Dissimilar Properties of Two Recombinant Lactobacillus acidophilus Strains Displaying Salmonella FliC with Different Anchoring Motifs

Kajikawa, A., Nordone, S. K., Zhang, L., Stoeker, L. L., LaVoy, A. S., Klaenhammer, T. R., & Dean, G. A. (2011, July 23). Applied and Environmental Microbiology.

By: A. Kajikawa n, S. Nordone*, L. Zhang*, L. Stoeker*, A. LaVoy*, T. Klaenhammer n, G. Dean*

MeSH headings : Acids / metabolism; Antigens, Bacterial / genetics; Antigens, Bacterial / metabolism; Cells, Cultured; Cytokines / metabolism; Dendritic Cells / immunology; Dendritic Cells / microbiology; Drug Carriers; Drug Stability; Flagellin / genetics; Flagellin / metabolism; Genetic Vectors; Humans; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / metabolism; Peptide Hydrolases / metabolism; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Salmonella Vaccines / genetics; Salmonella Vaccines / immunology; Vaccines, Synthetic / genetics; Vaccines, Synthetic / immunology
topics (OpenAlex): Probiotics and Fermented Foods; Viral gastroenteritis research and epidemiology; Bacteriophages and microbial interactions
TL;DR: Two recombinant L. acidophilus derivatives displaying Salmonella flagellin were constructed using different anchor motifs, and the surface-associated antigen was highly sensitive to simulated gastric and small intestinal juices. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2011 article

Partial Regulatory T Cell Depletion Prior to Acute Feline Immunodeficiency Virus Infection Does Not Alter Disease Pathogenesis

Mikkelsen, S. R., Long, J. M., Zhang, L., Galemore, E. R., VandeWoude, S., & Dean, G. A. (2011, February 25). PLoS ONE.

By: S. Mikkelsen n, J. Long  n, L. Zhang n, E. Galemore n, S. VandeWoude * & G. Dean n

MeSH headings : Acute Disease; Acute-Phase Reaction / immunology; Animals; Antibodies, Monoclonal / administration & dosage; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / pathology; Cat Diseases / immunology; Cat Diseases / virology; Cats; Disease Progression; Down-Regulation / immunology; Feline Acquired Immunodeficiency Syndrome / etiology; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / pathology; Feline Acquired Immunodeficiency Syndrome / virology; Female; Immunodeficiency Virus, Feline / immunology; Immunodeficiency Virus, Feline / physiology; Interleukin-2 Receptor alpha Subunit / immunology; Lymphocyte Count; Lymphocyte Depletion / methods; Lymphocyte Depletion / veterinary; Specific Pathogen-Free Organisms; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / pathology; Viremia / veterinary
topics (OpenAlex): HIV Research and Treatment; Immune Cell Function and Interaction; T-cell and B-cell Immunology
TL;DR: It is reported here that partial Treg cell depletion prior to FIV infection does not significantly change provirus, viremia, or CD4+ T cell levels in blood and lymphoid tissues during the acute phase of disease. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 article

Mycobacterium chelonae sensitisation induces CD4+‐mediated cytotoxicity against BCG

Ho, P., Zhang, L., Wei, X., & Seah, G. T. (2009, July 1). European Journal of Immunology.

By: P. Ho *, L. Zhang n, X. Wei * & G. Seah*

author keywords: Bacterial infections; CD4 T cells; Cytotoxicity; Host-pathogen interactions; Immune responses
MeSH headings : Animals; Antibodies / immunology; CD4-Positive T-Lymphocytes / cytology; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / metabolism; CD56 Antigen / immunology; CD8-Positive T-Lymphocytes / cytology; CD8-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / metabolism; Cytotoxicity, Immunologic / immunology; Fas Ligand Protein / immunology; Fas Ligand Protein / metabolism; Flow Cytometry; Interferon-gamma / immunology; Interferon-gamma / metabolism; Interleukin-10 / immunology; Interleukin-10 / metabolism; Lung / immunology; Lung / microbiology; Lung / pathology; Mice; Mice, Inbred BALB C; Mycobacterium bovis / immunology; Mycobacterium chelonae / immunology; Perforin / immunology; Perforin / metabolism; Tuberculosis / immunology; Tuberculosis / microbiology; Tuberculosis / veterinary
topics (OpenAlex): Mycobacterium research and diagnosis; Tuberculosis Research and Epidemiology; Immunodeficiency and Autoimmune Disorders
TL;DR: This is the first report describing cytotoxicity against BCG‐infected cells as a mechanism underlying the influence of Env sensitisation on subsequent BCG responses, and it is postulated that it could be due to Env‐specific T cells exerting cytot toxicity againstBCG‐ Infected host cells. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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