Works (5)

Updated: August 3rd, 2023 21:15

2019 journal article

EPA and DHA Inhibit Myogenesis and Downregulate the Expression of Muscle-related Genes in C2C12 Myoblasts

Genes, 10(1), 64.

author keywords: C2C12; proliferation; differentiation; EPA; DHA
MeSH headings : Animals; Cell Differentiation; Cell Line; Docosahexaenoic Acids / pharmacology; Down-Regulation; Eicosapentaenoic Acid / pharmacology; Insulin-Like Growth Factor II / genetics; Insulin-Like Growth Factor II / metabolism; MAP Kinase Signaling System; Mice; Muscle Development; Myoblasts / cytology; Myoblasts / drug effects; Myoblasts / metabolism; Myoglobin / genetics; Myoglobin / metabolism; Myosin Heavy Chains / genetics; Myosin Heavy Chains / metabolism; Myosin Light Chains / genetics; Myosin Light Chains / metabolism; Troponin / genetics; Troponin / metabolism
TL;DR: It is suggested that EPA and DHA exerted an inhibitory effect on myoblast proliferation and differentiation and downregulated muscle-related genes expression. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: March 18, 2019

2019 journal article

Shifts in the Composition and Activities of Denitrifiers Dominate CO2 Stimulation of N2O Emissions


MeSH headings : Carbon Dioxide; Denitrification; Nitrogen; Nitrous Oxide; Soil; Soil Microbiology
TL;DR: The results suggest that effective management of N sources may mitigate N2O emissions by negating eCO2-stimulation of soil denitrifying microbes and their activities. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 28, 2019

2011 journal article

Dissimilar Properties of Two Recombinant Lactobacillus acidophilus Strains Displaying Salmonella FliC with Different Anchoring Motifs


By: A. Kajikawa n, S. Nordone, L. Zhang*, L. Stoeker*, A. LaVoy*, T. Klaenhammer n, G. Dean*

MeSH headings : Acids / metabolism; Antigens, Bacterial / genetics; Antigens, Bacterial / metabolism; Cells, Cultured; Cytokines / metabolism; Dendritic Cells / immunology; Dendritic Cells / microbiology; Drug Carriers; Drug Stability; Flagellin / genetics; Flagellin / metabolism; Genetic Vectors; Humans; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / metabolism; Peptide Hydrolases / metabolism; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Salmonella Vaccines / genetics; Salmonella Vaccines / immunology; Vaccines, Synthetic / genetics; Vaccines, Synthetic / immunology
TL;DR: Two recombinant L. acidophilus derivatives displaying Salmonella flagellin were constructed using different anchor motifs, and the surface-associated antigen was highly sensitive to simulated gastric and small intestinal juices. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Partial Regulatory T Cell Depletion Prior to Acute Feline Immunodeficiency Virus Infection Does Not Alter Disease Pathogenesis

PLOS ONE, 6(2).

By: S. Mikkelsen n, J. Long n, L. Zhang n, E. Galemore n, S. VandeWoude* & G. Dean n

MeSH headings : Acute Disease; Acute-Phase Reaction / immunology; Animals; Antibodies, Monoclonal / administration & dosage; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / pathology; Cat Diseases / immunology; Cat Diseases / virology; Cats; Disease Progression; Down-Regulation / immunology; Feline Acquired Immunodeficiency Syndrome / etiology; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / pathology; Feline Acquired Immunodeficiency Syndrome / virology; Female; Immunodeficiency Virus, Feline / immunology; Immunodeficiency Virus, Feline / physiology; Interleukin-2 Receptor alpha Subunit / immunology; Lymphocyte Count; Lymphocyte Depletion / methods; Lymphocyte Depletion / veterinary; Specific Pathogen-Free Organisms; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / pathology; Viremia / veterinary
TL;DR: It is reported here that partial Treg cell depletion prior to FIV infection does not significantly change provirus, viremia, or CD4+ T cell levels in blood and lymphoid tissues during the acute phase of disease. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Mycobacterium chelonae sensitisation induces CD4(+)-mediated cytotoxicity against BCG


By: P. Ho*, L. Zhang n, X. Wei* & G. Seah*

author keywords: Bacterial infections; CD4 T cells; Cytotoxicity; Host-pathogen interactions; Immune responses
MeSH headings : Animals; Antibodies / immunology; CD4-Positive T-Lymphocytes / cytology; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / metabolism; CD56 Antigen / immunology; CD8-Positive T-Lymphocytes / cytology; CD8-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / metabolism; Cytotoxicity, Immunologic / immunology; Fas Ligand Protein / immunology; Fas Ligand Protein / metabolism; Flow Cytometry; Interferon-gamma / immunology; Interferon-gamma / metabolism; Interleukin-10 / immunology; Interleukin-10 / metabolism; Lung / immunology; Lung / microbiology; Lung / pathology; Mice; Mice, Inbred BALB C; Mycobacterium bovis / immunology; Mycobacterium chelonae / immunology; Perforin / immunology; Perforin / metabolism; Tuberculosis / immunology; Tuberculosis / microbiology; Tuberculosis / veterinary
TL;DR: This is the first report describing cytotoxicity against BCG‐infected cells as a mechanism underlying the influence of Env sensitisation on subsequent BCG responses, and it is postulated that it could be due to Env‐specific T cells exerting cytot toxicity againstBCG‐ Infected host cells. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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