Works Published in 2017

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Displaying all 7 works

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2017 journal article

An inclusive Research Education Community (iREC): Impact of the SEA-PHAGES program on research outcomes and student learning

Proceedings of the National Academy of Sciences, 114(51), 13531–13536.

By: D. Hanauer*, M. Graham*, L. Betancur*, A. Bobrownicki*, S. Cresawn*, R. Garlena*, D. Jacobs-Sera*, N. Kaufmann* ...

author keywords: bacteriophage; genomics; science education; evolution; assessment
MeSH headings : Biomedical Research / education; Biomedical Research / standards; Education, Medical, Undergraduate / methods; Education, Medical, Undergraduate / standards; Female; Humans; Learning; Male; Program Evaluation; Teaching; Universities / standards; Young Adult
TL;DR: The SEA-PHAGES students show strong gains correlated with persistence relative to those in traditional laboratory courses regardless of academic, ethnic, gender, and socioeconomic profiles. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 19, 2020

2017 journal article

Safety and Efficacy of Allogeneic Lung Spheroid Cells in a Mismatched Rat Model of Pulmonary Fibrosis

STEM CELLS TRANSLATIONAL MEDICINE, 6(10), 1905–1916.

By: J. Cores n, M. Hensley n, K. Kinlaw n, S. Rikard n, P. Dinh n, D. Paudel n, J. Tang n, A. Vandergriff n ...

author keywords: Fibrosis; Pulmonary; Syngeneic; Allogeneic; Stem cells
MeSH headings : Animals; Bleomycin / toxicity; Cells, Cultured; Female; Lung / cytology; Pulmonary Fibrosis / etiology; Pulmonary Fibrosis / therapy; Rats; Rats, Wistar; Spheroids, Cellular / transplantation; Stem Cell Transplantation / adverse effects; Stem Cell Transplantation / methods; Transplantation, Homologous / adverse effects; Transplantation, Homologous / methods
TL;DR: It is found that infusion of allogeneic LSCs reduces the progression of inflammation and fibrotic manifestation and preserves epithelial and endothelial health without eliciting significant immune rejection. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

An Evaluation of University Recreation Center Outdoor Programs for People With Disabilities: Perspectives From Professionals

JOURNAL OF OUTDOOR RECREATION EDUCATION AND LEADERSHIP, 9(1), 83–97.

By: E. Daniels n, M. Cottingham*, D. Walsh* & D. Pearson*

author keywords: outdoor adventure programs; students with disabilities; recreational programming
UN Sustainable Development Goal Categories
4. Quality Education (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Derivation of therapeutic lung spheroid cells from minimally invasive transbronchial pulmonary biopsies

RESPIRATORY RESEARCH, 18.

By: P. Dinh n, J. Cores n, M. Hensley n, A. Vandergriff n, J. Tang n, T. Allen n, T. Caranasos*, K. Adler n, L. Lobo*, K. Cheng n

author keywords: Pulmonary progenitor cells; Lung spheroid; Stem cell
MeSH headings : Adolescent; Aged; Animals; Biopsy; Bronchi / cytology; Bronchi / physiology; Cell Culture Techniques / methods; Female; Human Umbilical Vein Endothelial Cells / physiology; Humans; Infusions, Intravenous; Lung / cytology; Lung / physiology; Male; Mice; Mice, Nude; Middle Aged; Spheroids, Cellular / physiology; Stem Cell Transplantation / methods; Stem Cells / physiology
TL;DR: These cells could be utilized in long-term expansion of lung progenitor cells and as part of the development of cell-based therapies for the treatment of lung diseases such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

A Regenerative Cardiac Patch Formed by Spray Painting of Biomaterials onto the Heart

TISSUE ENGINEERING PART C-METHODS, 23(3), 146–155.

author keywords: cardiac patch; platelet fibrin gel; myocardial infarction; regeneration
MeSH headings : Animals; Biocompatible Materials / chemistry; Blood Platelets / metabolism; Fibrin / metabolism; Heart / physiology; Male; Mice; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Paintings; Rats; Rats, Sprague-Dawley; Regeneration / physiology
TL;DR: The use of the spraying system allowed for placement of a uniform cardiac patch on the heart in a mini-invasive manner without the need for sutures or glue, and promoted cardiac repair and attenuated cardiac dysfunction after MI. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome

NATURE COMMUNICATIONS, 8.

By: J. Tang*, D. Shen*, T. Caranasos*, Z. Wang*, A. Vandergriff n, T. Allen n, M. Hensley n, P. Dinh n ...

MeSH headings : Animals; Biomimetic Materials / chemistry; Biomimetic Materials / metabolism; Biomimetic Materials / pharmacology; Cell Fractionation; Cell Membrane / chemistry; Cell Membrane / metabolism; Cell Membrane / transplantation; Cell-Derived Microparticles / chemistry; Cell-Derived Microparticles / metabolism; Cell-Derived Microparticles / transplantation; Culture Media, Conditioned / chemistry; Culture Media, Conditioned / isolation & purification; Disease Models, Animal; Gene Expression; Hepatocyte Growth Factor / genetics; Hepatocyte Growth Factor / metabolism; Humans; Injections, Intralesional; Insulin-Like Growth Factor I / genetics; Insulin-Like Growth Factor I / metabolism; Intercellular Signaling Peptides and Proteins / pharmacology; Male; Mice; Myocardial Infarction / metabolism; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocardium / metabolism; Myocardium / pathology; Paracrine Communication; Recovery of Function / drug effects; Stem Cells / cytology; Stem Cells / metabolism; Vascular Endothelial Growth Factor A / genetics; Vascular Endothelial Growth Factor A / metabolism
TL;DR: A synthetic cell-mimicking microparticle that recapitulates stem cell functions in tissue repair and acts as ‘synthetic stem cells’ which mimic the paracrine and biointerfacing activities of natural stem cells in therapeutic cardiac regeneration. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Angiopellosis as an Alternative Mechanism of Cell Extravasation

STEM CELLS, 35(1), 170–180.

By: T. Allen n, D. Gracieux n, M. Talib n, D. Tokarz n, M. Hensley n, J. Cores n, A. Vandergriff n, J. Tang n ...

author keywords: Extravasation; Angiopellosis; Transmigration; Stem cell infusion; Diapedesis
MeSH headings : Animals; Blood Vessels / physiology; CD11 Antigens / metabolism; Cell Aggregation; Cell Membrane / metabolism; Cell Shape; Dogs; Extravasation of Diagnostic and Therapeutic Materials / pathology; Female; Humans; Injections; Intravital Microscopy; Male; Mesenchymal Stem Cells; Microspheres; Myocytes, Cardiac / cytology; Polymers / chemistry; Rats; Time Factors; Transendothelial and Transepithelial Migration; Zebrafish / metabolism
TL;DR: In injected cardiac and mesenchymal stem cells, the vascular wall undergoes an extensive remodeling to allow the cell to exit the lumen, while the injected cell remains distinctively passive in activity. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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