Works Published in 2018
Displaying works 101 - 120 of 252 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2018 journal article
Preparation of photodynamic P(MMA-co-MAA) composite nanofibers doped with MMT: A facile method for increasing antimicrobial efficiency
Applied Surface Science, 457, 247–255.
author keywords: Montmorillonite; Photodynamic; Nanofiber; Electrospinning; Photosensitizer; Antibacterial
TL;DR:
The results demonstrate that MMT and similar additives may be a universal method for increasing the adsorption capacity of cationic photosensitizers in electrospun nanofibers, thereby generating materials with improved photodynamic inactivation efficacy without significantly changing the fiber morphology, cost, or ease of production.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020
2018 journal article
Photooxidation Properties of Photosensitizer/Direct Dye Patterned Polyester/Cotton Fabrics
Fibers and Polymers, 19(8), 1687–1693.
author keywords: Cationic dyeable polyester; Polyester/cotton knitted fabric; Dyeing process; Antimicrobial; Photooxidation
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020
2018 journal article
Silica-Supported Lipid Bilayers: Electrostatic Effects at Lipid Interfaces as Reported by Spin-Labeling EPR
Biophysical Journal, 114(3), 96a.
www.cell.com (publisher PDF)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020
2018 journal article
Characterization of the Spectral Accuracy of an Orbitrap Mass Analyzer Using Isotope Ratio Mass Spectrometry
Analytical Chemistry, 90(3), 1897–1906.
MeSH headings : Caffeine / analysis; Carbon Isotopes / analysis; Nitrogen Isotopes / analysis; Oligopeptides / analysis; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods; Sulfur Isotopes / analysis
TL;DR:
It is demonstrated that at optimum absolute ions abundances the Orbitrap can be used to accurately count carbons, nitrogens, and sulfurs in samples with varying masses and absolute monoisotopic ion abundances required for high SA were empirically determined by using the expected and experimental isotopic distributions to calculate the Pearson chi-square test.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: February 21, 2020
2018 journal article
Jürgen H. Gross: Mass spectrometry: a textbook, 3rd ed.
Analytical and Bioanalytical Chemistry, 410(8), 2051–2052.
TL;DR:
To effectively make use of modern mass spectrometry for chemical and biological systems, one needs to understand the principles of the technique including ionization methods, mass analyzer technology, and ion dissociation as well as a basic understanding of isotopic distributions and measuring mass.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 21, 2020
2018 journal article
Interdependent Roles of Electrostatics and Surface Functionalization on the Adhesion Strengths of Nanodiamonds to Gold in Aqueous Environments Revealed by Molecular Dynamics Simulations
The Journal of Physical Chemistry Letters, 9(15), 4396–4400.
TL;DR:
Molecular dynamics simulations demonstrate that adhesion strengths as a function of charge for aqueous nanodiamonds interacting with a gold substrate result from an interdependence of electrostatics and surface functionalization.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Crossref
Added: February 18, 2020
2018 journal article
Electrochemical Selectivity Achieved Using a Double Voltammetric Waveform and Partial Least Squares Regression: Differentiating Endogenous Hydrogen Peroxide Fluctuations from Shifts in pH
Analytical Chemistry, 90(3), 1767–1776.
MeSH headings : Animals; Brain / metabolism; Electrochemical Techniques / methods; Hydrogen Peroxide / metabolism; Hydrogen-Ion Concentration; Least-Squares Analysis; Male; Principal Component Analysis; Rats, Sprague-Dawley
TL;DR:
The data demonstrate that the double waveform PLSR model is a powerful tool that can be used to disambiguate and evaluate naturally occurring H2O2 fluctuations in vivo.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: February 5, 2020
2018 journal article
Quantitative Comparison of Enzyme Immobilization Strategies for Glucose Biosensing in Real-Time Using Fast-Scan Cyclic Voltammetry Coupled with Carbon-Fiber Microelectrodes
ChemPhysChem, 19(10), 1197–1204.
author keywords: biosensing; carbon-fiber microelectrodes; cyclic voltammetry; dopamine; glucose
MeSH headings : Animals; Biosensing Techniques; Carbon / chemistry; Electrochemical Techniques; Enzymes, Immobilized; Glucose / analysis; Glucose Oxidase / metabolism; Male; Microelectrodes; Rats; Rats, Sprague-Dawley; Time Factors
TL;DR:
Comparing three approaches to enzyme immobilization on the microelectrode surface-physical adsorption, hydrogel entrapment, andEntrapment in electrospun nanofibers suggests that each of these methods can be used to create functional microbiosensors.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: February 5, 2020
2018 content posted
Lactobacillus acidophilus disrupts collaborative multispecies bile acid metabolism
TL;DR:
It is discovered that a decrease in ursocholate abundance corresponded with successful weight loss in patients after gastric bypass surgery versus those who did not lose weight after surgery, which highlights a new microbe-to-microbe interaction mediated by bile acids.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: December 16, 2019
2018 journal article
Online Ozonolysis Combined with Ion Mobility-Mass Spectrometry Provides a New Platform for Lipid Isomer Analyses
Analytical Chemistry, 90(2), 1292–1300.
Contributors: B. Poad *, X. Zheng *, T. Mitchell *, R. Smith *, E. Baker* & S. Blanksby *
MeSH headings : Chromatography, High Pressure Liquid / instrumentation; Equipment Design; Humans; Ion Mobility Spectrometry / instrumentation; Isomerism; Lipids / analysis; Lipids / blood; Ozone / chemistry; Tandem Mass Spectrometry / instrumentation
TL;DR:
The combination of OzID with multidimensional separations shows significant promise for facile profiling of unsaturation patterns within complex lipidomes including human plasma.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions
(OpenAlex)
Source: ORCID
Added: December 5, 2019
2018 journal article
Unraveling the isomeric heterogeneity of glycans: Ion mobility separations in structures for lossless ion manipulations
Chemical Communications, 54(83), 11701–11704.
Contributors: G. Nagy *, I. Attah *, S. Garimella *, K. Tang *, Y. Ibrahim *, E. Baker* , R. Smith *
TL;DR:
A structures for lossless ion manipulations (SLIM) serpentine ultra-long path with extended routing (SUPER) ion mobility-mass spectrometry platform to achieve much higher resolution of isomeric glycoforms to address the challenges associated with glycan analyses.
(via Semantic Scholar)
Source: ORCID
Added: December 5, 2019
2018 journal article
The MPLEx protocol for multi-omic analyses of soil samples
Journal of Visualized Experiments, 2018(135).
Contributors: C. Nicora *, K. Burnum-Johnson *, E. Nakayasu *, C. Casey *, R. White *, T. Chowdhury *, J. Kyle *, Y. Kim *
author keywords: Chemistry; Issue 135; MPLEx; Metaproteomics; Lipidomics; Metabolomics; Multi-omics; Mass Spectrometry
MeSH headings : Mass Spectrometry / methods; Metabolomics / methods; Soil / chemistry
TL;DR:
A 3-in-1 method for the simultaneous extraction of metabolites, proteins, and lipids from the same soil sample was created by adapting a solvent-based approach, which has proven to be both simple and robust for many sample types, even when utilized for limited quantities of complex soil samples.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: December 5, 2019
2018 journal article
Recent advances in lipid separations and structural elucidation using mass spectrometry combined with ion mobility spectrometry, ion-molecule reactions and fragmentation approaches
Current Opinion in Chemical Biology, 42, 111–118.
Contributors: X. Zheng *, R. Smith * & E. Baker*
MeSH headings : Ion Mobility Spectrometry / methods; Isomerism; Lipids / chemistry; Lipids / classification; Lipids / isolation & purification; Mass Spectrometry / methods; Molecular Structure
TL;DR:
To aid in isomer characterization, ion mobility spectrometry separations, ion-molecule reactions and fragmentation techniques have increasingly been added to lipid analysis workflows and their capabilities for improving the identification of lipid species are reviewed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Source: ORCID
Added: December 5, 2019
2018 journal article
Rapid Ion Mobility Separations of Bile Acid Isomers Using Cyclodextrin Adducts and Structures for Lossless Ion Manipulations
Analytical Chemistry, 90(18), 11086–11091.
Contributors: C. Chouinard *, G. Nagy *, I. Webb *, S. Garimella *, E. Baker* , Y. Ibrahim *, R. Smith *
MeSH headings : Bile Acids and Salts / chemistry; Bile Acids and Salts / isolation & purification; Cyclodextrins / chemistry; Ions / chemistry; Ions / isolation & purification; Isomerism; Mass Spectrometry / economics; Mass Spectrometry / methods; Models, Molecular; Time Factors
TL;DR:
Cyclodextrin adducts were utilized in conjunction with novel ion mobility (IM) separation capabilities provided by structures for lossless ion manipulations (SLIM) that resulted in much higher resolution separations and increased signal intensities for the BA isomers studied.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
Source: ORCID
Added: December 5, 2019
2018 journal article
High-throughput serum proteomics for the identification of protein biomarkers of mortality in older men
Aging Cell, 17(2).
Contributors: E. Orwoll *, J. Wiedrick*, J. Jacobs *, E. Baker* , P. Piehowski *, V. Petyuk *, Y. Gao *, T. Shi *
author keywords: aging; biomarker; inflammation; men; mortality; proteomics
MeSH headings : Biomarkers / chemistry; Humans; Male; Mortality; Proteomics / methods
TL;DR:
The results suggest that complex inflammatory pathways, and proteins in other pathways, are linked to 5‐year mortality risk.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: December 5, 2019
2018 journal article
Utilizing Ion Mobility Spectrometry and Mass Spectrometry for the Analysis of Polycyclic Aromatic Hydrocarbons, Polychlorinated Biphenyls, Polybrominated Diphenyl Ethers and Their Metabolites
Analytica Chimica Acta, 1037, 265–273.
Contributors: X. Zheng *, K. Dupuis*, N. Aly*, Y. Zhou *, F. Smith*, K. Tang *, R. Smith *, E. Baker*
author keywords: Ion mobility spectrometry; Collision cross section; Xenobiotics; Polycyclic aromatic hydrocarbons; Polychlorinated biphenyls; Polybrominated diphenyl ethers; Electrospray ionization; Atmospheric pressure chemical ionization; Atmospheric pressure photoionization
MeSH headings : Chromatography, Liquid; Halogenated Diphenyl Ethers / analysis; Halogenated Diphenyl Ethers / metabolism; Ion Mobility Spectrometry; Mass Spectrometry; Molecular Structure; Polybrominated Biphenyls / analysis; Polybrominated Biphenyls / metabolism; Polycyclic Aromatic Hydrocarbons / analysis; Polycyclic Aromatic Hydrocarbons / metabolism
TL;DR:
The rapid isomeric and molecular separations possible with IMS-MS showed great promise for quickly distinguishing the parent and metabolized PAH, PCB, and PDBE molecules in complex environmental and biological samples.
(via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: December 5, 2019
2018 journal article
Using Skyline to Analyze Data-Containing Liquid Chromatography, Ion Mobility Spectrometry, and Mass Spectrometry Dimensions
Journal of the American Society for Mass Spectrometry, 29(11), 2182–2188.
Contributors: B. MacLean *, B. Pratt *, J. Egertson*, M. MacCoss *, R. Smith * & E. Baker*
author keywords: Ion mobility spectrometry; Skyline; Data independent acquisition; Proteomics
TL;DR:
This study showcases Skyline’s ability to work with the multidimensional LC-IMS-CID-MS data and provide biological and environmental insights rapidly and presents an important informatics development.
(via Semantic Scholar)
Source: ORCID
Added: December 5, 2019
2018 journal article
Towards Discovery and Targeted Peptide Biomarker Detection Using nanoESI-TIMS-TOF MS
Journal of the American Society for Mass Spectrometry, 29(5), 817–826.
Contributors: A. Garabedian*, P. Benigni*, C. Ramirez*, E. Baker* , T. Liu *, R. Smith *, F. Fernandez-Lima *
author keywords: Discovery and targeted monitoring; Trapped ion mobility spectrometry; Mass; Spectrometry; Biomarker detection; Quantitative proteomics
MeSH headings : Amino Acid Sequence; Biomarkers, Tumor / analysis; Breast Neoplasms / chemistry; Breast Neoplasms / pathology; Female; Humans; Ion Mobility Spectrometry / methods; Peptides / analysis; Proteomics / methods; Spectrometry, Mass, Electrospray Ionization / methods; Tandem Mass Spectrometry / methods; Workflow
TL;DR:
The TIMS-TOF MS analysis permitted peptide biomarker detection based on accurate mobility, mass measurements, and high sequence coverage for concentrations in the 10–200 nM range, while simultaneously achieving discovery measurements of not initially targeted peptides as markers from the same proteins and, eventually, other proteins.
(via Semantic Scholar)
Source: ORCID
Added: December 5, 2019
2018 journal article
Improved Sensitivity and Separations for Phosphopeptides using Online Liquid Chromotography Coupled with Structures for Lossless Ion Manipulations Ion Mobility-Mass Spectrometry
Analytical Chemistry, 90(18), 10889–10896.
Contributors: C. Chouinard *, G. Nagy *, I. Webb *, T. Shi *, E. Baker* , S. Prost*, T. Liu *, Y. Ibrahim *, R. Smith *
MeSH headings : Amino Acid Sequence; Bacterial Proteins / analysis; Bacterial Proteins / isolation & purification; Chromatography, Reverse-Phase / methods; Humans; Ion Mobility Spectrometry / methods; Isomerism; Mass Spectrometry / methods; Phosphopeptides / analysis; Phosphopeptides / isolation & purification; Shewanella / chemistry
TL;DR:
LC-SLIM IM-MS offers great potential for improving the sensitivity, separation, and throughput of phosphoproteomics analyses, with additional gains projected with the future use of longer path SLIM IM separations.
(via Semantic Scholar)
Source: ORCID
Added: December 5, 2019
2018 journal article
Evaluating lipid mediator structural complexity using ion mobility spectrometry combined with mass spectrometry
Bioanalysis, 10(5), 279–289.
Contributors: J. Kyle *, N. Aly*, X. Zheng *, K. Burnum-Johnson *, R. Smith * & E. Baker*
author keywords: collision cross-section; ion mobility spectrometry; lipid mediators
MeSH headings : Animals; Arachidonic Acid / chemistry; Chromatography, Liquid; Docosahexaenoic Acids / analogs & derivatives; Docosahexaenoic Acids / chemistry; Humans; Influenza A virus / growth & development; Ion Mobility Spectrometry; Isomerism; Linoleic Acid / chemistry; Lung / virology; Mass Spectrometry; Mice; Tissue Extracts / chemistry
TL;DR:
Adding IMS separations to conventional LC-MS analyses show great utility for enabling better identification and characterization of LMs in complex biological samples.
(via Semantic Scholar)
Source: ORCID
Added: December 5, 2019
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