Works Published in 2010
Displaying works 241 - 260 of 675 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2010 journal article
Evaluation of an in vitro telomeric repeat amplification protocol assay to detect telomerase activity in canine urine
American Journal of Veterinary Research, 71(12), 1468–1474.
MeSH headings : Animals; Carcinoma, Transitional Cell / enzymology; Carcinoma, Transitional Cell / urine; Carcinoma, Transitional Cell / veterinary; Cell Line, Tumor; Dog Diseases / enzymology; Dog Diseases / urine; Dogs / urine; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Fibroblasts / enzymology; Lung / enzymology; Polymerase Chain Reaction / methods; Telomerase / analysis; Telomerase / urine; Telomere / genetics
TL;DR:
The TRAP-based assay detected telomerase activity in the canine TCC cell line and revealed that the telomersase ribonucleoprotein complex was inherently unstable at various storage durations and conditions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, ORCID, NC State University Libraries
Added: July 20, 2019
2010 chapter
Peripheral Nerve Disorders
In S. J. Ettinger & E. C. Feldman (Eds.), Textbook of Veterinary Internal Medicine (7th edition., pp. 1462–1467). St. Louis, MO: Saunders Elsevier.
Ed(s): S. Ettinger & E. Feldman
Source: NC State University Libraries
Added: July 11, 2019
2010 journal article
Protein-Like Copolymers (PLCs) as Compatibilizers for Homopolymer Blends
Macromolecules, 43(11), 5149–5157.
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: March 29, 2019
2010 journal article
A facile approach to fabricate porous nylon 6 nanofibers using silica nanotemplate
Journal of Applied Polymer Science, 120(1), 425–433.
author keywords: electrospinning; nanocomposite; porous nanofibers; Nylon 6
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: March 25, 2019
2010 journal article
Zwitterionic phosphorylcholine as a better ligand for gold nanorods cell uptake and selective photothermal ablation of cancer cells
Chemical Communications, 46(9), 1479–1481.
MeSH headings : Cell Line, Tumor; Gold / chemistry; Humans; Infrared Rays; Ligands; Metal Nanoparticles / chemistry; Microscopy, Electron, Transmission; Phosphorylcholine / chemistry
TL;DR:
The conjugation of zwitterionic phosphorylcholine onto gold nanorods leads to enhanced and selective uptake within cancer cells.
(via Semantic Scholar)
Source: ORCID
Added: March 21, 2019
2010 article
Signal Generation with Gold Nanoparticles: Photophysical Properties for Sensor and Imaging Applications
Wei, Q., & Wei, A. (2010, June). The Supramolecular Chemistry of Organic-Inorganic Hybrid Materials, pp. 319–349.
Source: ORCID
Added: March 21, 2019
2010 journal article
Plasmon-Resonant Nanoparticles and Nanostars with Magnetic Cores: Synthesis and Magnetomotive Imaging
Acs Nano, 4(9), 5163–5173.
author keywords: imaging; magnetic nanoparticles; nanomedicine; nanostars; plasmonics; synthesis
MeSH headings : Animals; Cattle; Cell Line; Gold / chemistry; Macrophages / metabolism; Magnetics; Magnetite Nanoparticles / chemistry; Mice; Microscopy, Electron, Transmission; Molecular Imaging / methods; Optical Phenomena; Protein Transport; Serum Albumin, Bovine / metabolism
TL;DR:
The polarization-sensitive MM imaging modality offers the dual advantage of enhanced signal quality and reduced background signal and can be applied toward the detection of magnetomotive NSTs in heterogeneous biological samples, as illustrated by their detection inside of granular cells such as macrophages.
(via Semantic Scholar)
europepmc.org (repository)
Source: ORCID
Added: March 21, 2019
2010 journal article
Gold nanorods: multifunctional agents for cancer imaging and therapy.
Methods in Molecular Biology (Clifton, N.J.), 624, 119–130.
author keywords: Gold; biomedical imaging; nonlinear optical microscopy; photothermal effects; surface functionalization; targeting
MeSH headings : Animals; Diagnostic Imaging / methods; Folic Acid / metabolism; Gold; Mice; Nanomedicine / methods; Nanotubes / chemistry; Nanotubes / ultrastructure; Neoplasms / diagnosis; Neoplasms / therapy; Polyethylene Glycols / metabolism; Surface Properties
TL;DR:
Gold nanorods are strongly absorbing at near-infrared (NIR) frequencies and can be employed as multifunctional agents for biological imaging and theragnostics, but future clinical applications will require the rigorous removal of CTAB and reliable methods of surface functionalization for cell-selective targeting and for minimizing nonspecific uptake into cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: ORCID
Added: March 21, 2019
2010 article
Cellular Interactions of Plasmon-Resonant Gold Nanorods
Wei, Q., & Wei, A. (2010, August). Organelle-Specific Pharmaceutical Nanotechnology, pp. 507–533.
Source: ORCID
Added: March 21, 2019
2010 journal article
The phylogenetic origins of natural killer receptors and recognition: relationships, possibilities, and realities
Immunogenetics, 63(3), 123–141.
author keywords: Marsupial; Monotreme; Chicken; Xenopus; Zebrafish; Innate immunity; Cytotoxicity
MeSH headings : Animals; Evolution, Molecular; Humans; Immunity, Innate; Killer Cells, Natural / immunology; Mammals / genetics; Mammals / immunology; Phylogeny; Receptors, Natural Killer Cell / genetics; Receptors, Natural Killer Cell / immunology; Receptors, Natural Killer Cell / metabolism; Vertebrates / genetics; Vertebrates / immunology
TL;DR:
Several lines of evidence suggest that NK-type function or its equivalent has sustained a long evolutionary history throughout vertebrate species and likely reflects the influence of pathogens on their evolution.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, NC State University Libraries, Crossref
Added: February 13, 2019
2010 journal article
Increased numbers of myeloid and lymphoid IL-10 producing cells in spleen of pigs with naturally occurring postweaning multisystemic wasting syndrome
Veterinary Immunology and Immunopathology, 136(3-4), 305–310.
Source: ORCID
Added: February 11, 2019
2010 journal article
Experimental infection with H1N1 European swine influenza virus protects pigs from an infection with the 2009 pandemic H1N1 human influenza virus.
Veterinary Research, 41(5), 74.
author keywords: influenza virus; swine H1N1; human A(H1N1) 2009; cross-protection
MeSH headings : Animals; Humans; Influenza A Virus, H1N1 Subtype / immunology; Lung / pathology; Orthomyxoviridae Infections / immunology; Orthomyxoviridae Infections / pathology; Orthomyxoviridae Infections / veterinary; Orthomyxoviridae Infections / virology; Pandemics; RNA, Viral; Swine
TL;DR:
Assessment of the risk posed by the A(H1N1) 2009 in the actual situation of swine farms sought to analyze whether a previous infection with a circulating European avian-like swine A/Swine/Spain/53207/2004 generated or not cross-protective immunity against a subsequent infection with the new human pandemic A/Catalonia/63/2009 (H1n1) influenza virus (hereafter referred to as pH1N 1).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: February 11, 2019
2010 journal article
Interferon-gamma induction correlates with protection by DNA vaccine expressing E2 glycoprotein against classical swine fever virus infection in domestic pigs.
Veterinary Microbiology, 142(1-2), 51–58.
author keywords: Classical swine fever virus; DNA vaccines; Interferon-gamma; Protection
MeSH headings : Animals; Antibodies, Viral / blood; Cell Line; Classical Swine Fever / immunology; Classical Swine Fever / prevention & control; Classical Swine Fever Virus / immunology; Interferon-gamma / immunology; Swine; Time Factors; Vaccines, DNA / immunology; Viral Envelope Proteins / immunology; Viral Vaccines / immunology
TL;DR:
P pigs vaccinated with the DNA vaccine induced a strong cellular immune response, characterized by the specific induction IFN-gamma expressing T cells after vaccination without any detectable levels of CSFV neutralizing antibodies, which supports the relevance of the induction of a strong T cellular response to confer a solid protection upon DNA vaccination against CSfV.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: February 11, 2019
2010 journal article
Increased numbers of myeloid and lymphoid IL-10 producing cells in spleen of pigs with naturally occurring postweaning multisystemic wasting syndrome.
Veterinary Immunology and Immunopathology, 136(3-4), 305–310.
author keywords: Postweaning multisystemic wasting syndrome; Porcine circovirus type 2; Immunofluorescence assay; Interleukin-10; Spleen
MeSH headings : Animals; Circoviridae Infections / immunology; Circoviridae Infections / veterinary; Circoviridae Infections / virology; Circovirus / genetics; Circovirus / immunology; Fluorescent Antibody Technique, Indirect / veterinary; Immunophenotyping / methods; Immunophenotyping / veterinary; Interleukin-10 / immunology; Microscopy, Fluorescence; Porcine Postweaning Multisystemic Wasting Syndrome / immunology; Porcine Postweaning Multisystemic Wasting Syndrome / virology; RNA, Viral / blood; Reverse Transcriptase Polymerase Chain Reaction; Spleen / cytology; Spleen / immunology; Spleen / virology; Swine; Viral Load / immunology; Viral Load / veterinary
TL;DR:
This is the first immunophenotyping study on IL-10 producing cells in cases of PMWS, further extending the studies on the role of IL- 10 in disease pathogenesis.
(via Semantic Scholar)
Source: ORCID
Added: February 11, 2019
2010 journal article
Estudien el paper de la citoquina IL-10 en el desenvolupament de la circovirosi porcina
UAB Divulga, 0001–0002.
Source: ORCID
Added: February 11, 2019
2010 journal article
Corrigendum to “A proposal on porcine circovirus type 2 (PCV2) genotype definition and their relation with postweaning multisystemic wasting syndrome (PMWS) occurrence”[Vet. Microbiol. 128 (2008) 23--25]
Veterinary Microbiology, 141(1), 194.
Source: ORCID
Added: February 11, 2019
2010 journal article
Human lung mast cells mediate pneumococcal cell death in response to activation by pneumolysin
Journal of Immunology, 184(12), 7108–7115.
Contributors: G. Cruse* , V. Fernandes *, J. De Salort*, D. Pankhania*, M. Marinas*, H. Brewin*, P. Andrew *, P. Bradding *, A. Kadioglu *
MeSH headings : Bacterial Proteins / immunology; Cell Degranulation / immunology; Cells, Cultured; Coculture Techniques; Humans; Lung / cytology; Lung / immunology; Mast Cells / immunology; Mast Cells / microbiology; Pneumococcal Infections / immunology; Streptococcus pneumoniae / immunology; Streptolysins / immunology
TL;DR:
HLMCs exhibit direct antimicrobial activity to pneumococci through their activation by pneumolysin, and the release of LL-37 from HLMCs suggests that mast cells provide an early warning system and potentially limit pneumococcal dissemination early in the course of invasive pulmonary pneumitiscal disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: February 11, 2019
2010 journal article
Counterregulation of β<inf>2</inf>-adrenoceptor function in human mast cells by stem cell factor
Journal of Allergy and Clinical Immunology, 125(1-3).
Contributors: G. Cruse* , W. Yang*, S. Duffy*, L. Chachi*, M. Leyland*, Y. Amrani*, P. Bradding *
author keywords: beta(2)-Adrenoceptor; albuterol; asthma; mast cell; desensitization
MeSH headings : Albuterol / metabolism; Albuterol / pharmacology; Asthma / drug therapy; Asthma / metabolism; Asthma / physiopathology; Cell Line; Histamine Release; Humans; Lung / cytology; Lung / drug effects; Mast Cells / drug effects; Mast Cells / immunology; Mast Cells / metabolism; Potassium Channels, Calcium-Activated / metabolism; Receptors, Adrenergic, beta-2 / drug effects; Receptors, Adrenergic, beta-2 / metabolism; Stem Cell Factor / metabolism; Stem Cell Factor / pharmacology
TL;DR:
Albuterol actually potentiated IgE-induced histamine release in a dose-dependent manner when both SCF and IgE were present, suggesting the potentially beneficial effects of beta(2)-adrenoceptor agonists in asthmatic airways may be blunted as a result of the high concentrations of SCF present.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: February 11, 2019
2010 journal article
Airway smooth muscle proliferation and survival is not modulated by mast cells
Clinical and Experimental Allergy, 40(2), 279–288.
Contributors: D. Kaur *, F. Hollins*, R. Saunders *, L. Woodman*, A. Sutcliffe*, G. Cruse* , P. Bradding *, C. Brightling *
author keywords: airway smooth muscle; apoptosis; asthma; mast cells; necrosis; proliferation; survival
MeSH headings : Aged; Apoptosis; Asthma / immunology; Asthma / pathology; Cell Proliferation; Cell Survival; Cells, Cultured; Coculture Techniques; Female; Humans; Immunoglobulin E / immunology; Male; Mast Cells / immunology; Mast Cells / physiology; Middle Aged; Muscle, Smooth / metabolism; Muscle, Smooth / pathology
TL;DR:
Background Airway smooth muscle (ASM) hyperplasia and mast cell localization within the ASM bundle are important features of asthma and the cause of this increased ASM mass is uncertain.
(via Semantic Scholar)
Source: ORCID
Added: February 11, 2019
2010 journal article
Activation of human mast cells through the platelet-activating factor receptor
Journal of Allergy and Clinical Immunology, 125(5).
Contributors: N. Kajiwara*, T. Sasaki*, P. Bradding *, G. Cruse* , H. Sagara *, K. Ohmori *, H. Saito *, C. Ra *, Y. Okayama*
author keywords: Anaphylaxis; histamine; human lung mast cells; human peripheral blood-derived mast cells; human skin mast cells; platelet-activating factor receptor
MeSH headings : Anaphylaxis / immunology; Anaphylaxis / physiopathology; Cells, Cultured; Histamine Release; Humans; Lung / cytology; Mast Cells / cytology; Mast Cells / immunology; Mast Cells / metabolism; Platelet Activating Factor / metabolism; Platelet Membrane Glycoproteins / metabolism; Receptors, G-Protein-Coupled / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Skin / cytology
TL;DR:
The findings provide a mechanism whereby PAF mediates an amplification loop for MC activation in the generation of anaphylaxis, and it is shown for the first time that PAF induces histamine release from human lung MCs and PB-derived MCs but not skin MCs.
(via Semantic Scholar)
Source: ORCID
Added: February 11, 2019
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