Glenn Paul Cruse

The exon-skipping oligonucleotide, KitStop, depletes tissue-resident mast cells in vivo to ameliorate anaphylaxis

FRONTIERS IN IMMUNOLOGY, 14.

Identification of redundancy between human Fc epsilon RI beta and MS4A6A proteins points toward additional complex mechanisms for Fc epsilon RI trafficking and signaling

Bitting, K., Hedgespeth, B., Ehrhardt-Humbert, L. C., Arthur, G. K., Schubert, A. G., Bradding, P., … Cruse, G. (2022, December 7). ALLERGY, Vol. 12.

Regulation of Trafficking and Signaling of the High Affinity IgE Receptor by Fc epsilon RI beta and the Potential Impact of Fc epsilon RI beta Splicing in Allergic Inflammation

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(2).

Targeting KIT by frameshifting mRNA transcripts as a therapeutic strategy for aggressive mast cell neoplasms

MOLECULAR THERAPY, 30(1), 295–310.

Dermal Extracellular Matrix-Derived Hydrogels as an In Vitro Substrate to Study Mast Cell Maturation

TISSUE ENGINEERING PART A, 27(15-16), 1008–1022.

Identification of an ATP/P2X7/mast cell pathway mediating ozone-induced bronchial hyperresponsiveness

JCI INSIGHT, 6(21).

Mast Cell-Biomaterial Interactions and Tissue Repair

TISSUE ENGINEERING PART B-REVIEWS, 27(6), 590–603.

Nanosilver composite pNIPAm microgels for the development of antimicrobial platelet-like particles

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 108(6), 2599–2609.

Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch

CELL REPORTS, 31(1).

The FcεRIβ homologue, MS4A4A, promotes FcεRI signal transduction and store-operated Ca2+ entry in human mast cells

Cellular Signalling, 71, 109617.

Exon Skipping of Fc epsilon RI beta for Allergic Diseases

EXON SKIPPING AND INCLUSION THERAPIES: METHODS AND PROTOCOLS, Vol. 1828, pp. 503–518.

Constitutive KIT Activity and IL-6 Production in Mast Cells Alters Levels of Reactive Oxygen Species (ROS) and the Scavenger Protein DJ-1 in Mastocytosis

Journal of Allergy and Clinical Immunology, 137(2), AB281.

Exon skipping of Fc epsilon RI beta eliminates expression of the high-affinity IgE receptor in mast cells with therapeutic potential for allergy

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(49), 14115–14120.

Immunophenotypic and ultrastructural analysis of mast cells in hermansky-pudlak syndrome type-1: A possible connection to pulmonary fibrosis

PLoS ONE, 11(7).

Mast cells in airway diseases and interstitial lung disease

European Journal of Pharmacology, 778, 125–138.

Vibratory urticaria associated with a missense variant in ADGRE2

New England Journal of Medicine, 374(7), 656–663.

Constitutively Activated KIT in Mastocytosis Patients Is Associated with Decreased Levels of the Scavenger Protein DJ1 and Reciprocal Increases in Reactive Oxygen Species

Journal of Allergy and Clinical Immunology, 135(2), AB389.

Flow cytometry-based monitoring of mast cell activation

In Methods in Molecular Biology (Vol. 1220, pp. 365–379).

Mast Cells Expressing the Germline HPS1 16-Bp Duplication (c.1470_1486dup16, Hermansky-Pudlak Syndrome-1) Defect Produce Extracellular Matrix Components

Journal of Allergy and Clinical Immunology, 135(2), AB172.

The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recycling

Molecular Biology of the Cell, 26(9), 1711–1727.

The Fcεriβ Homologue, MS4A4, Promotes Fcεri-Dependent Human Mast Cell Degranulation By Facilitating PLCγ1 Signaling

Journal of Allergy and Clinical Immunology, 135(2), AB240.

Functional deregulation of KIT: Link to mast cell proliferative diseases and other neoplasms

Immunology and Allergy Clinics of North America, 34(2), 219–237.

Rictor negatively regulates high-affinity receptors for IgE-induced mast cell degranulation

Journal of Immunology, 193(12), 5924–5932.

A Truncated Splice-Variant of the FcεRIβ Receptor Subunit Is Critical for Microtubule Formation and Degranulation in Mast Cells

Immunity, 38(5), 906–917.

Diminished allergic disease in patients with STAT3 mutations reveals a role for STAT3 signaling in mast cell degranulation

Journal of Allergy and Clinical Immunology, 132(6).

Diminished allergic disease in patients with STAT3 mutations reveals a role for STAT3 signaling in mast cell degranulation

Journal of Allergy and Clinical Immunology, 132(6), 1388–1396.e3.

Establishment of the Hermansky Pudlak Mastocyte (HPM) Cell Line Which Has the HPS1 16-Bp Duplication (c.1470_1486dup16)

Journal of Allergy and Clinical Immunology, 131(2), AB115.

Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions

New England Journal of Medicine, 366(4), 330–338.

Functional KCa3.1 K⁺ channels are required for human fibrocyte migration

Journal of Allergy and Clinical Immunology, 128(6).

A novel FcεRIβ-chain truncation regulates human mast cell proliferation and survival

FASEB Journal, 24(10), 4047–4057.

Activation of human mast cells through the platelet-activating factor receptor

Journal of Allergy and Clinical Immunology, 125(5).

Airway smooth muscle proliferation and survival is not modulated by mast cells

Clinical and Experimental Allergy, 40(2), 279–288.

Counterregulation of β2-adrenoceptor function in human mast cells by stem cell factor

Journal of Allergy and Clinical Immunology, 125(1-3).

Human lung mast cells mediate pneumococcal cell death in response to activation by pneumolysin

Journal of Immunology, 184(12), 7108–7115.

Airway wall geometry in asthma and nonasthmatic eosinophilic bronchitis

Allergy: European Journal of Allergy and Clinical Immunology, 64(6), 951–958.

IL-13 expression by blood T cells and not eosinophils is increased in asthma compared to non-asthmatic eosinophilic bronchitis

BMC Pulmonary Medicine, 9.

Mast Cells: Biological Properties and Role in Health and Allergic Diseases

In Allergy and Allergic Diseases, Second Edition (Vol. 1, pp. 217–257).

Engagement of the EP2 prostanoid receptor closes the K⁺ channel KCa3.1 in human lung mast cells and attenuates their migration

European Journal of Immunology, 38(9), 2548–2556.

Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: Cooperative roles for CADM1, stem cell factor, and IL-6

Journal of Immunology, 181(4), 2772–2780.

IgE alone promotes human lung mast cell survival through the autocrine production of IL-6

BMC Immunology, 9.

Mast cells promote airway smooth muscle cell differentiation via autocrine up-regulation of TGF-β1

Journal of Immunology, 181(7), 5001–5007. http://www.scopus.com/inward/record.url?eid=2-s2.0-58149280835&partnerID=MN8TOARS

Adenosine closes the K⁺ channel KCa3.1 in human lung mast cells and inhibits their migration via the adenosine A2A receptor

European Journal of Immunology, 37(6), 1653–1662.

KCa3.1 Ca²⁺-activated K⁺ channels regulate human airway smooth muscle proliferation

American Journal of Respiratory Cell and Molecular Biology, 37(5), 525–531.

Functional KCa3.1 K⁺ channels are required for human lung mast cell migration

Thorax, 61(10), 880–885.

Activation of human lung mast cells by monomeric immunoglobulin E

European Respiratory Journal, 25(5), 858–863.

Activation of human lung mast cells by monomeric immunoglobulin E (multiple letters) [2]

European Respiratory Journal, 26(4), 744–746.

β2-adrenoceptor regulation of the K⁺ channel iKCa1 in human mast cells

FASEB Journal, 19(8), 1006–1008.

The K ⁺ channel iK CA1 potentiates Ca ²⁺ influx and degranulation in human lung mast cells

Journal of Allergy and Clinical Immunology, 114(1), 66–72.