Works (41)

2020 article

Nanosilver composite pNIPAm microgels for the development of antimicrobial platelet-like particles

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS.

By: E. Chee, S. Nandi, K. Nellenbach, E. Mihalko, D. Snider, L. Morrill, A. Bond, E. Sproul ...

Sources: Web Of Science, ORCID
Added: March 16, 2020

2020 journal article

Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch

CELL REPORTS, 31(1).

By: S. Mishra, J. Wheeler, S. Pitake, H. Ding, C. Jiang, T. Fukuyama, J. Paps, P. Ralph ...

Sources: Web Of Science, ORCID
Added: April 27, 2020

2020 journal article

The FcεRIβ homologue, MS4A4A, promotes FcεRI signal transduction and store-operated Ca2+ entry in human mast cells

Cellular Signalling, 71, 109617.

By: G. Arthur, L. Ehrhardt-Humbert, D. Snider, C. Jania, S. Tilley, D. Metcalfe, G. Cruse

Source: ORCID
Added: April 10, 2020

2018 chapter

Exon Skipping of Fc epsilon RI beta for Allergic Diseases

In EXON SKIPPING AND INCLUSION THERAPIES: METHODS AND PROTOCOLS (Vol. 1828, pp. 503–518).

By: G. Arthur & G. Cruse

Sources: NC State University Libraries, ORCID
Added: March 4, 2019

2016 journal article

Constitutive KIT Activity and IL-6 Production in Mast Cells Alters Levels of Reactive Oxygen Species (ROS) and the Scavenger Protein DJ-1 in Mastocytosis

Journal of Allergy and Clinical Immunology, 137(2), AB281.

By: D. Kim, M. Beaven, J. Kulinski, A. Desai, G. Cruse, C. Prussin, H. Komarow, M. Carter, D. Metcalfe, A. Olivera

Sources: Crossref, ORCID
Added: January 25, 2020

2016 journal article

Exon skipping of FcϵRIβ eliminates expression of the high-affinity IgE receptor in mast cells with therapeutic potential for allergy

Proceedings of the National Academy of Sciences of the United States of America, 113(49), 14115–14120.

By: G. Cruse, Y. Yin, T. Fukuyama, A. Desai, G. Arthur, W. Bäumer, M. Beaven, D. Metcalfe

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Immunophenotypic and ultrastructural analysis of mast cells in hermansky-pudlak syndrome type-1: A possible connection to pulmonary fibrosis

PLoS ONE, 11(7).

Source: ORCID
Added: February 11, 2019

2016 journal article

Mast cells in airway diseases and interstitial lung disease

European Journal of Pharmacology, 778, 125–138.

By: G. Cruse & P. Bradding

Source: ORCID
Added: February 11, 2019

2016 journal article

Vibratory urticaria associated with a missense variant in ADGRE2

New England Journal of Medicine, 374(7), 656–663.

By: S. Boyden, A. Desai, G. Cruse, M. Young, H. Bolan, L. Scott, A. Robin Eisch, R. Daniel Long ...

Source: ORCID
Added: February 11, 2019

2015 journal article

Constitutively Activated KIT in Mastocytosis Patients Is Associated with Decreased Levels of the Scavenger Protein DJ1 and Reciprocal Increases in Reactive Oxygen Species

Journal of Allergy and Clinical Immunology, 135(2), AB389.

By: D. Kim, M. Beaven, G. Cruse, C. Prussin, H. Komarow, M. Carter, D. Metcalfe, A. Olivera

Sources: Crossref, ORCID
Added: January 25, 2020

2015 book

Flow cytometry-based monitoring of mast cell activation

In Methods in Molecular Biology (Vol. 1220, pp. 365–379).

By: G. Cruse, A. Gilfillan & D. Smrz

Source: ORCID
Added: February 11, 2019

2015 journal article

Mast Cells Expressing the Germline HPS1 16-Bp Duplication (c.1470_1486dup16, Hermansky-Pudlak Syndrome-1) Defect Produce Extracellular Matrix Components

Journal of Allergy and Clinical Immunology, 135(2), AB172.

By: A. Kirshenbaum, G. Bandara, A. Desai, E. Fischer, M. Leerkes, D. Metcalfe, G. Cruse

Sources: Crossref, ORCID
Added: January 25, 2020

2015 journal article

The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recycling

Molecular Biology of the Cell, 26(9), 1711–1727.

By: G. Cruse, M. Beaven, S. Music, P. Bradding, A. Gilfillan & D. Metcalfe

Source: ORCID
Added: February 11, 2019

2015 journal article

The Fcεriβ Homologue, MS4A4, Promotes Fcεri-Dependent Human Mast Cell Degranulation By Facilitating PLCγ1 Signaling

Journal of Allergy and Clinical Immunology, 135(2), AB240.

By: G. Cruse, M. Beaven, S. Music, P. Bradding & D. Metcalfe

Sources: Crossref, ORCID
Added: January 25, 2020

2014 journal article

Functional deregulation of KIT: Link to mast cell proliferative diseases and other neoplasms

Immunology and Allergy Clinics of North America, 34(2), 219–237.

By: G. Cruse, D. Metcalfe & A. Olivera

Source: ORCID
Added: February 11, 2019

2014 journal article

Rictor negatively regulates high-affinity receptors for IgE-induced mast cell degranulation

Journal of Immunology, 193(12), 5924–5932.

By: D. Smrz, G. Cruse, M. Beaven, A. Kirshenbaum, D. Metcalfe & A. Gilfillan

Source: ORCID
Added: February 11, 2019

2013 journal article

A Truncated Splice-Variant of the FcεRIβ Receptor Subunit Is Critical for Microtubule Formation and Degranulation in Mast Cells

Immunity, 38(5), 906–917.

By: G. Cruse, M. Beaven, I. Ashmole, P. Bradding, A. Gilfillan & D. Metcalfe

Source: ORCID
Added: February 11, 2019

2013 journal article

Diminished allergic disease in patients with STAT3 mutations reveals a role for STAT3 signaling in mast cell degranulation

Journal of Allergy and Clinical Immunology, 132(6).

Source: ORCID
Added: February 11, 2019

2013 journal article

Diminished allergic disease in patients with STAT3 mutations reveals a role for STAT3 signaling in mast cell degranulation

Journal of Allergy and Clinical Immunology, 132(6), 1388–1396.e3.

By: A. Siegel, K. Stone, G. Cruse, M. Lawrence, A. Olivera, M. Jung, J. Barber, A. Freeman ...

Sources: Crossref, ORCID
Added: February 5, 2020

2013 journal article

Establishment of the Hermansky Pudlak Mastocyte (HPM) Cell Line Which Has the HPS1 16-Bp Duplication (c.1470_1486dup16)

Journal of Allergy and Clinical Immunology, 131(2), AB115.

By: A. Kirshenbaum, A. Desai, G. Bandara, G. Cruse, E. Fischer, A. Gilfillan, W. Gahl, D. Metcalfe

Sources: Crossref, ORCID
Added: February 5, 2020

2012 journal article

Cold urticaria, immunodeficiency, and autoimmunity related to PLCG2 deletions

New England Journal of Medicine, 366(4), 330–338.

By: M. Ombrello, E. Remmers, G. Sun, A. Freeman, S. Datta, P. Torabi-Parizi, N. Subramanian, T. Bunney ...

Source: ORCID
Added: February 11, 2019

2011 journal article

Functional KCa3.1 K+ channels are required for human fibrocyte migration

Journal of Allergy and Clinical Immunology, 128(6).

By: G. Cruse, S. Singh, S. Duffy, C. Doe, R. Saunders, C. Brightling, P. Bradding

Source: ORCID
Added: February 11, 2019

2010 journal article

A novel FcεRIβ-chain truncation regulates human mast cell proliferation and survival

FASEB Journal, 24(10), 4047–4057.

By: G. Cruse, D. Kaur, M. Leyland & P. Bradding

Source: ORCID
Added: February 11, 2019

2010 journal article

Activation of human mast cells through the platelet-activating factor receptor

Journal of Allergy and Clinical Immunology, 125(5).

By: N. Kajiwara, T. Sasaki, P. Bradding, G. Cruse, H. Sagara, K. Ohmori, H. Saito, C. Ra, Y. Okayama

Source: ORCID
Added: February 11, 2019

2010 journal article

Airway smooth muscle proliferation and survival is not modulated by mast cells

Clinical and Experimental Allergy, 40(2), 279–288.

By: D. Kaur, F. Hollins, R. Saunders, L. Woodman, A. Sutcliffe, G. Cruse, P. Bradding, C. Brightling

Source: ORCID
Added: February 11, 2019

2010 journal article

Counterregulation of β2-adrenoceptor function in human mast cells by stem cell factor

Journal of Allergy and Clinical Immunology, 125(1-3).

By: G. Cruse, W. Yang, S. Duffy, L. Chachi, M. Leyland, Y. Amrani, P. Bradding

Source: ORCID
Added: February 11, 2019

2010 journal article

Human lung mast cells mediate pneumococcal cell death in response to activation by pneumolysin

Journal of Immunology, 184(12), 7108–7115.

By: G. Cruse, V. Fernandes, J. De Salort, D. Pankhania, M. Marinas, H. Brewin, P. Andrew, P. Bradding, A. Kadioglu

Source: ORCID
Added: February 11, 2019

2009 journal article

Airway wall geometry in asthma and nonasthmatic eosinophilic bronchitis

Allergy: European Journal of Allergy and Clinical Immunology, 64(6), 951–958.

By: S. Siddiqui, S. Gupta, G. Cruse, P. Haldar, J. Entwisle, S. McDonald, P. Whithers, S. Hainsworth, H. Coxson, C. Brightling

Source: ORCID
Added: February 11, 2019

2009 journal article

IL-13 expression by blood T cells and not eosinophils is increased in asthma compared to non-asthmatic eosinophilic bronchitis

BMC Pulmonary Medicine, 9.

By: S. Siddiqui, G. Cruse, S. Mckenna, W. Monteiro, V. Mistry, A. Wardlaw, C. Brightling

Source: ORCID
Added: February 11, 2019

2009 book

Mast Cells: Biological Properties and Role in Health and Allergic Diseases

In Allergy and Allergic Diseases, Second Edition (Vol. 1, pp. 217–257).

By: P. Bradding & G. Cruse

Source: ORCID
Added: February 11, 2019

2008 journal article

Engagement of the EP2 prostanoid receptor closes the K+ channel KCa3.1 in human lung mast cells and attenuates their migration

European Journal of Immunology, 38(9), 2548–2556.

By: S. Duffy, G. Cruse, S. Cockerill, C. Brightling & P. Bradding

Source: ORCID
Added: February 11, 2019

2008 journal article

Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: Cooperative roles for CADM1, stem cell factor, and IL-6

Journal of Immunology, 181(4), 2772–2780.

By: F. Hollins, D. Kaur, W. Yang, G. Cruse, R. Saunders, A. Sutcliffe, P. Berger, A. Ito, C. Brightling, P. Bradding

Source: ORCID
Added: February 11, 2019

2008 journal article

IgE alone promotes human lung mast cell survival through the autocrine production of IL-6

BMC Immunology, 9.

By: G. Cruse, S. Cockerill & P. Bradding

Source: ORCID
Added: February 11, 2019

2008 journal article

Mast cells promote airway smooth muscle cell differentiation via autocrine up-regulation of TGF-β1

Journal of Immunology, 181(7), 5001–5007.

By: L. Woodman, S. Siddiqui, G. Cruse, A. Sutcliffe, R. Saunders, D. Kaur, P. Bradding, C. Brightling

Source: ORCID
Added: February 11, 2019

2007 journal article

Adenosine closes the K+ channel KCa3.1 in human lung mast cells and inhibits their migration via the adenosine A2A receptor

European Journal of Immunology, 37(6), 1653–1662.

By: S. Duffy, G. Cruse, C. Brightling & P. Bradding

Source: ORCID
Added: February 11, 2019

2007 journal article

KCa3.1 Ca2+-activated K+ channels regulate human airway smooth muscle proliferation

American Journal of Respiratory Cell and Molecular Biology, 37(5), 525–531.

By: M. Shepherd, S. Duffy, T. Harris, G. Cruse, M. Schuliga, C. Brightling, C. Neylon, P. Bradding, A. Stewart

Source: ORCID
Added: February 11, 2019

2006 journal article

Functional KCa3.1 K+ channels are required for human lung mast cell migration

Thorax, 61(10), 880–885.

By: G. Cruse, S. Duffy, C. Brightling & P. Bradding

Source: ORCID
Added: February 11, 2019

2005 journal article

Activation of human lung mast cells by monomeric immunoglobulin E

European Respiratory Journal, 25(5), 858–863.

By: G. Cruse, D. Kaur, W. Yang, S. Duffy, C. Brightling & P. Bradding

Source: ORCID
Added: February 11, 2019

2005 journal article

Activation of human lung mast cells by monomeric immunoglobulin E (multiple letters) [2]

European Respiratory Journal, 26(4), 744–746.

By: S. Hart, I. Dransfield, P. Bradding & G. Cruse

Source: ORCID
Added: February 11, 2019

2005 journal article

β2-adrenoceptor regulation of the K+ channel iKCa1 in human mast cells

FASEB Journal, 19(8), 1006–1008.

By: S. Duffy, G. Cruse, W. Lawley & P. Bradding

Source: ORCID
Added: February 11, 2019

2004 journal article

The K + channel iK CA1 potentiates Ca 2+ influx and degranulation in human lung mast cells

Journal of Allergy and Clinical Immunology, 114(1), 66–72.

By: S. Mark Duffy, P. Berger, G. Cruse, W. Yang, S. Bolton & P. Bradding

Source: ORCID
Added: February 11, 2019

Employment

2016 - present

North Carolina State University Raleigh, NC, US
Assistant Professor Molecular Biomedical Sciences