Works Published in 2005
Displaying works 81 - 100 of 501 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2005 journal article
Structure-guided saturation mutagenesis of N-acetylneuraminic acid lyase for the synthesis of sialic acid mimetics
Protein Engineering, Design and Selection, 18(5), 239–246.
author keywords: N-acetylneuraminic acid lyase; sialic acid mimetics; structure-guided saturation mutagenesis; synthesis
MeSH headings : Amides / metabolism; Amino Acid Substitution; Biomimetics; Escherichia coli / enzymology; Molecular Structure; Mutagenesis; N-Acetylneuraminic Acid / metabolism; Oxo-Acid-Lyases / chemistry; Oxo-Acid-Lyases / genetics; Protein Engineering; Structure-Activity Relationship; Substrate Specificity
TL;DR:
Engineering efforts provide a scaffold for the further tailoring of NAL for the synthesis of sialic acid mimetics, including 6-dipropylcarboxamides, through structure-guided saturation mutagenesis.
(via Semantic Scholar)
academic.oup.com (publisher PDF)
Sources: Crossref, NC State University Libraries
Added: December 22, 2020
2005 journal article
The Met-Tyr-Trp Cross-link in Mycobacterium tuberculosis Catalase-peroxidase (KatG)
Journal of Biological Chemistry, 280(24), 22651–22663.
Contributors: R. Ghiladi* , G. Knudsen *, K. Medzihradszky * & P. Ortiz De Montellano*
MeSH headings : Amino Acid Sequence; Bacterial Proteins / chemistry; Bacterial Proteins / physiology; Binding Sites; Catalase / chemistry; Catalase / physiology; Catalysis; Chromatography, High Pressure Liquid; Cross-Linking Reagents / pharmacology; Crystallography, X-Ray; Heme / chemistry; Hydrogen Peroxide / chemistry; Kinetics; Mass Spectrometry; Methionine / chemistry; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mycobacterium tuberculosis / enzymology; Peptides / chemistry; Peracetic Acid / chemistry; Plasmids / metabolism; Protein Binding; Recombinant Proteins / chemistry; Spectrophotometry; Time Factors; Trypsin / pharmacology; Tryptophan / chemistry; Tyrosine / chemistry; Ultraviolet Rays
TL;DR:
The structure-function-spectroscopy relationship in KatG is discussed with relevance to the role that the Met-Tyr-Trp cross-link plays in the catalase-peroxidase mechanism.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 15, 2020
2005 journal article
Role of the Met−Tyr−Trp Cross-Link inMycobacterium tuberculosis Catalase-Peroxidase (KatG) As Revealed by KatG(M255I)
Biochemistry, 44(46), 15093–15105.
Contributors: R. Ghiladi* , K. Medzihradszky * & P. Ortiz De Montellano*
MeSH headings : Amino Acid Sequence; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Catalase / chemistry; Catalase / genetics; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Mass Spectrometry; Methionine / chemistry; Molecular Sequence Data; Peptide Fragments / chemistry; Peracetic Acid / chemistry; Peroxidases / analysis; Spectrophotometry; Spectrophotometry, Ultraviolet; Tryptophan / chemistry; Tyrosine / chemistry
TL;DR:
Insight into the contributions of the individual Tyr-Trp and Met-Tyr cross-links to catalase activity is presented, as is the overall contribution of the Met-tyr-trp cross-link to the structure-function-spectroscopy relationship and catalases-peroxidase mechanism in KatG.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 15, 2020
2005 journal article
Heme-copper/dioxygen adduct formation relevant to cytochrome c oxidase: Spectroscopic characterization of [(<sup>6</sup>L)Fe<sup>III</sup>-(O <inf>2</inf><sup>2-</sup>)-Cu<sup>II</sup>]<sup>+</sup>
Journal of Biological Inorganic Chemistry, 10(1), 63–77.
Contributors: R. Ghiladi* , H. Huang *, P. Moënne-Loccoz *, J. Stasser*, N. Blackburn *, A. Woods *, R. Cotter *, C. Incarvito*, A. Rheingold *, K. Karlin *
author keywords: heme-copper; iron(II)-copper(I) complex; peroxo complex; mass spectrometry; resonance Raman spectroscopy; dioxygen adduct; model compound
MeSH headings : Binding Sites; Copper / chemistry; Copper / metabolism; Electron Transport Complex IV / chemistry; Electron Transport Complex IV / metabolism; Heme / chemistry; Heme / metabolism; Molecular Conformation; Oxygen / chemistry; Oxygen / metabolism; Solvents; Spectrum Analysis; Temperature
TL;DR:
1H and 2H NMR spectroscopy reveals that 2 is the first heme-copper peroxo complex which is high-spin, with downfield-shifted pyrrole resonances and upfield shifted peaks at δ= −22, −35, and −40 ppm, similar to the pattern observed for the μ-oxocomplex.
(via Semantic Scholar)
Source: ORCID
Added: December 15, 2020
2005 journal article
Correlation between Isoniazid Resistance and Superoxide Reactivity in Mycobacterium tuberculosis KatG
Journal of the American Chemical Society, 127(38), 13428–13442.
Contributors: R. Ghiladi* , K. Medzihradszky *, F. Rusnak* & P. Ortiz De Montellano*
MeSH headings : Bacterial Proteins / chemistry; Catalase / chemistry; Drug Resistance, Microbial; Free Radicals / chemistry; Isoniazid / chemistry; Isoniazid / pharmacology; Mycobacterium tuberculosis / drug effects; Mycobacterium tuberculosis / enzymology; Oxidation-Reduction; Oxygen Consumption / drug effects; Structure-Activity Relationship; Time Factors
TL;DR:
A mechanism for isoniazid resistance which accounts for the observed reactivity for each of the compound I, II, and III intermediates is proposed and suggests that the compound III pathway may be the primary factor in determining overall isoniaZid resistance by specific KatG mutants, with secondary contributions arising from the compounds I and II pathways.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: December 15, 2020
2005 encyclopedia entry
Dirhodium(II) Tetrakis[R 2-oxaazetidine-4(S)-carboxylate]
In Encyclopedia of Reagents for Organic Synthesis.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Source: ORCID
Added: December 15, 2020
2005 journal article
Adiabatic demagnetization of a pyrochlore antiferromagnet Gd<inf>2</inf>Ti<inf>2</inf>O<inf>7</inf>
Journal of Magnetism and Magnetic Materials, 290-291 PART 1, 709–711.
Contributors: S. Sosin *, L. Prozorova*, A. Smirnov* , A. Golov *, I. Berkutov*, O. Petrenko *, G. Balakrishnan *, M. Zhitomirsky*
author keywords: magnetocaloric effect; frustration; rare-earth compounds
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: ORCID
Added: December 4, 2020
2005 journal article
Magnetocaloric effect in pyrochlore antiferromagnet Gd<inf>2</inf>Ti<inf>2</inf>O<inf>7</inf>
Physical Review B - Condensed Matter and Materials Physics, 71(9).
Contributors: S. Sosin *, L. Prozorova*, A. Smirnov* , A. Golov *, I. Berkutov*, O. Petrenko *, G. Balakrishnan *, M. Zhitomirsky*
Source: ORCID
Added: December 4, 2020
2005 journal article
Field-controlled phase separation at the impurity-induced magnetic ordering in the spin-peierls magnet CuGeO<inf>3</inf>
Physical Review Letters, 94(5).
Contributors: V. Glazkov *, A. Smirnov* , H. Von Nidda *, A. Loidl *, K. Uchinokura* & T. Masuda *
TL;DR:
The paramagnetic fraction surviving at the impurity-induced antiferromagnetic phase transition in the spin-Peierls magnet CuGeO3 is found to increase with an external magnetic field.
(via Semantic Scholar)
Source: ORCID
Added: December 4, 2020
2005 journal article
The method of possible states and its application to the chemical thermodynamic analysis of nonequilibrium processes in a multicomponent mixture of reacting gases under isobaric adiabatic conditions
Theoretical Foundations of Chemical Engineering, 39(3), 250–258.
Contributors: A. Smirnov*
Source: ORCID
Added: December 4, 2020
2005 journal article
A cardiac myosin binding protein C mutation in the Maine Coon cat with familial hypertrophic cardiomyopathy
Human Molecular Genetics, 14(23), 3587–3593.
MeSH headings : Amino Acid Substitution; Animals; Cardiomyopathy, Hypertrophic / genetics; Carrier Proteins / genetics; Carrier Proteins / metabolism; Cats; Disease Models, Animal; Genotype; Muscle Proteins / genetics; Muscle Proteins / metabolism; Point Mutation; RNA, Messenger / metabolism; Sarcomeres / metabolism
TL;DR:
This is the first report of a spontaneous mutation causing HCM in a non-human species and feline familial HCM provides a valuable model for investigators to evaluate pathophysiologic processes and therapeutic manipulations.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: October 18, 2020
2005 journal article
Clinical, echocardiographic, and electrocardiographic abnormalities in Boxers with cardiomyopathy and left ventricular systolic dysfunction: 48 cases (1985-2003)
Journal of the American Veterinary Medical Association, 226(7), 1102–1104.
MeSH headings : Animals; Cardiomyopathies / diagnosis; Cardiomyopathies / physiopathology; Cardiomyopathies / veterinary; Dog Diseases / diagnosis; Dog Diseases / physiopathology; Dogs; Echocardiography / methods; Echocardiography / veterinary; Electrocardiography, Ambulatory / methods; Electrocardiography, Ambulatory / veterinary; Female; Male; Radiography, Thoracic / methods; Radiography, Thoracic / veterinary; Retrospective Studies; Ventricular Dysfunction, Left / diagnosis; Ventricular Dysfunction, Left / physiopathology; Ventricular Dysfunction, Left / veterinary
TL;DR:
Boxers with cardiomyopathy and left ventricular dysfunction frequently have arrhythmias of supraventricular or ventricular origin, and the natural history of myocardial disease in Boxers requires further study.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 18, 2020
2005 chapter
Molecular genetics of dilated cardiomyaopthy in the dog
In Canine Genetics (pp. 365–382). Cold Spring Harbor.
Source: NC State University Libraries
Added: October 10, 2020
2005 chapter
Canine Myocardial Disease
In Textbook of Veterinary Internal Medicine (6th ed., pp. 1077–1081). Philadelphia: WB Saunders.
Source: NC State University Libraries
Added: October 10, 2020
2005 chapter
Mechanism of lesion formation in canine atopic dermatitis: 2004 hypothesis
In A. Hillier, A. P. Foster, & K. W. Kwochka (Eds.), Advances in Veterinary Dermatology (Vol. 5, pp. 6–10). Oxford, UK: Blackwell Publishing.
Ed(s): A. Hillier, A. Foster & K. Kwochka
Source: NC State University Libraries
Added: September 22, 2020
2005 journal article
Treatment of canine pemphigus foliaceus
Derm Dialogue, 12–14.
Source: NC State University Libraries
Added: September 22, 2020
2005 journal article
Three-Dimensional Reconstruction for Medical-CAD Modeling
Computer-Aided Design and Applications, 2(1-4), 431–438.
TL;DR:
Methodology to generate bio-CAD models from high resolution non-invasive imaging, the medical image process and the 3D reconstruction technique will be described, enabling state-of-the-art computer programs to be enabled.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 10, 2020
2005 journal article
Screening Growth and Root Formation in Cadmium-Treated Turfgrass Using a Whole-Plant Microculture System
Journal of Plant Nutrition, 28(6), 1041–1048.
author keywords: bermudagrass; seashore paspalum; whole-plant microculture; phytoremediation
TL;DR:
Microculture at the whole-plant level in vitro enables intact root growth observations through the culture medium and vessel, and offers a potential pre-screening method for putative heavy-metal-tolerant turfgrasses before commercialization and use in phytoremediation to clean up contaminated soils.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 9, 2020
2005 journal article
Effects of Grape Cell Culture Extracts on Human Topoisomerase II Catalytic Activity and Characterization of Active Fractions
Journal of Agricultural and Food Chemistry, 53(7), 2489–2498.
author keywords: human topoisomerase II; catalytic inhibitor; antitopoisomerase II activity; Vitis; grape cell culture; chemopreventive agents
MeSH headings : Anticarcinogenic Agents; Cells, Cultured; Chemical Fractionation; Chromatography, High Pressure Liquid; Culture Media, Conditioned; DNA Topoisomerases, Type II / metabolism; Enzyme Inhibitors / isolation & purification; Enzyme Inhibitors / metabolism; Enzyme Inhibitors / pharmacology; Flavonoids / isolation & purification; Flavonoids / metabolism; Flavonoids / pharmacology; Glucosides / analysis; Humans; Phenols / isolation & purification; Phenols / metabolism; Phenols / pharmacology; Plant Extracts / chemistry; Plant Extracts / pharmacology; Polyphenols; Proanthocyanidins / analysis; Spectrometry, Mass, Electrospray Ionization; Vitis / metabolism
TL;DR:
The significant potency especially of TP-4 and TP-6 from grape cell cultures suggests that these fractions may have potential as chemopreventive agents.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 9, 2020
2005 journal article
Structural and Electron-Transfer Characteristics of O-, S-, and Se-Tethered Porphyrin Monolayers on Si(100) [J. Am. Chem. Soc.2004,126, 15603−15612].
Journal of the American Chemical Society, 127(25), 9308–9308.
TL;DR:
Collectively, the studies reported herein provide a detailed picture of how the anchor atom and the linker type influence the structural and electron-transfer characteristics of these general classes of monolayers.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 6, 2020
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.
