Alison B. Clode

Works (24)

Updated: July 5th, 2023 15:56

2015 journal article

Presumed primary ocular lymphangiosarcoma with metastasis in a miniature horse

Veterinary Ophthalmology, 18(6), 502–509.

By: J. Gerding n, B. Gilger n , S. Montgomery * & A. Clode n

author keywords: histopathology; horse; immunohistochemistry; lymphangiosarcoma; metastatic; ocular
MeSH headings : Animals; Corneal Diseases / diagnosis; Corneal Diseases / pathology; Corneal Diseases / therapy; Corneal Diseases / veterinary; Eye Neoplasms / diagnosis; Eye Neoplasms / pathology; Eye Neoplasms / therapy; Eye Neoplasms / veterinary; Fatal Outcome; Female; Horse Diseases / diagnosis; Horse Diseases / pathology; Horses; Lymphangiosarcoma / diagnosis; Lymphangiosarcoma / pathology; Lymphangiosarcoma / therapy; Lymphangiosarcoma / veterinary
TL;DR: A 7-year-old, 153.0-kg American Miniature mare presented for evaluation of keratoconjunctivitis of the right eye (OD), and a primary ocular lymphangiosarcoma with metastasis was diagnosed. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 review

Equine orbital fractures: a review of 18 cases (2006-2013)

[Review of ]. VETERINARY OPHTHALMOLOGY, 17, 97–106.

By: J. Gerding n, A. Clode n, B. Gilger n  & K. Montgomery n

author keywords: Complication; equine; fracture; orbital; outcome; retrospective
MeSH headings : Animals; Female; Horses / injuries; Male; Orbital Fractures / complications; Orbital Fractures / diagnostic imaging; Orbital Fractures / etiology; Orbital Fractures / therapy; Orbital Fractures / veterinary; Retrospective Studies; Tomography, X-Ray Computed / veterinary; Zygomatic Fractures / complications; Zygomatic Fractures / diagnostic imaging; Zygomatic Fractures / etiology; Zygomatic Fractures / therapy; Zygomatic Fractures / veterinary
TL;DR: Horses sustaining orbital fractures treated promptly with medical and surgical therapy have a favorable prognosis for return to function and cosmesis and warrant more aggressive therapy and decrease functional and cosmetic outcome. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Retrospective analysis of equine cataract surgery – visual outcomes vs age, IOL, and ERU status (35 cases)

Veterinary Ophthalmology, 17, 160–167.

By: M. Edelmann  n, R. McMullen n, R. Stoppini*, A. Clode n & B. Gilger n 

author keywords: cataracts; chronic uveitis; equine; intraocular lens; phacoemulsification; prognosis
MeSH headings : Age Factors; Animals; Cataract / veterinary; Female; Horses; Lenses, Intraocular / veterinary; Male; Phacoemulsification / adverse effects; Phacoemulsification / veterinary; Postoperative Complications / veterinary; Retrospective Studies; Treatment Outcome; Uveitis / etiology; Uveitis / veterinary; Vision Disorders / etiology; Vision Disorders / veterinary
TL;DR: Horses with chronic uveitis had significantly less favorable visual outcome after PA, and older age at surgery and IOL use were not associated with poor visual outcome. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 article

Veterinary Ophthalmology - Equine Ophthalmology Special Issue Preface

Clode, A., & Gilger, B. (2014, July). VETERINARY OPHTHALMOLOGY, Vol. 17, pp. 1–1.

By: A. Clode n & B. Gilger n 

MeSH headings : Animals; Eye Diseases / diagnosis; Eye Diseases / therapy; Eye Diseases / veterinary; Horse Diseases / diagnosis; Horse Diseases / therapy; Horses
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Evaluation of the effects of tricaine methanesulfonate on retinal structure and function in koi carp (Cyprinus carpio)

Journal of the American Veterinary Medical Association, 242(11), 1578–1582.

By: K. Bailey n, J. Hempstead, J. Tobias*, L. Borst* , A. Clode* & L. Posner*

MeSH headings : Aminobenzoates / adverse effects; Aminobenzoates / pharmacology; Anesthetics / adverse effects; Anesthetics / pharmacology; Animals; Carps; Fish Diseases / chemically induced; Retinal Diseases / chemically induced; Retinal Diseases / veterinary
TL;DR: Short-term exposure of koi carp to clinically relevant concentrations of MS-222 daily for up to 13 days was not associated with changes in retinal structure or function as measured in this study. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2013 journal article

Histopathologic features of equine superficial, nonhealing, corneal ulcers

Veterinary Ophthalmology, 17(s1), 46–52.

By: J. Hempstead, A. Clode n, B. Salmon & B. Gilger n 

author keywords: corneal; equine; indolent; nonhealing; superficial; ulcer
MeSH headings : Animals; Cornea / pathology; Corneal Stroma / pathology; Corneal Ulcer / pathology; Corneal Ulcer / veterinary; Epithelium, Corneal / pathology; Female; Horse Diseases / pathology; Horses; Male; Retrospective Studies
TL;DR: The most consistent histopathological characteristics of equine chronic, nonhealing, superficial, corneal ulcers include epithelial nonadherence, epithelial dysmaturity and mild to moderate stromal inflammation; however, one set of histopathology characteristics does not definitively define this syndrome in horses. (via Semantic Scholar)
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Added: August 6, 2018

2013 journal article

Treatment of immune-mediated keratitis in horses with episcleral silicone matrix cyclosporine delivery devices

Veterinary Ophthalmology, 17, 23–30.

By: B. Gilger n , R. Stoppini, D. Wilkie *, A. Clode n, N. Pinto n, J. Hempstead n, J. Gerding n, J. Salmon n

author keywords: cyclosporine; horse; immune-mediated; keratitis; sustained release
MeSH headings : Animals; Cyclosporine / administration & dosage; Cyclosporine / therapeutic use; Drug Implants / administration & dosage; Female; Horse Diseases / drug therapy; Horses; Immunosuppressive Agents / administration & dosage; Immunosuppressive Agents / therapeutic use; Keratitis / drug therapy; Keratitis / veterinary; Male; Sclera; Silicones; Treatment Outcome
TL;DR: Results from this preliminary retrospective study suggest that the ESMC implants were well tolerated and associated with treatment success with superficial and endothelial IMMK, especially if placed early in the disease process. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Identification and management of ocular lipid deposition in association with hyperlipidaemia in captive moray eels , Gymnothorax funebris Ranzani, Gymnothorax moringa (Cuvier) and Muraena retifera Goode and Bean

JOURNAL OF FISH DISEASES, 35(9), 683–693.

By: A. Clode n, C. Harms n , M. Fatzinger*, F. Young*, C. Colitz* & D. Wert*

author keywords: eye; Gymnothorax spp; lipid keratopathy; moray eel
MeSH headings : Animals; Blood Chemical Analysis; Diet; Eels; Eye Diseases / physiopathology; Eye Diseases / surgery; Eye Diseases / veterinary; Fish Diseases / pathology; Fish Diseases / prevention & control; Fish Diseases / surgery; Fisheries; Hyperlipidemias / pathology; Hyperlipidemias / prevention & control; Hyperlipidemias / surgery; Hyperlipidemias / veterinary; Lipids
TL;DR: Dietary management was minimally effective, while surgery improved ocular clarity within 1month post-operatively, in captive moray eels, which have an apparent predisposition for hyperlipidaemia and ocular lipid deposition. (via Semantic Scholar)
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14. Life Below Water (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Immunohistochemical and immunopathologic characterization of superficial stromal immune-mediated keratitis in horses

American Journal of Veterinary Research, 73(7), 1067–1073.

By: D. Pate n, A. Clode n, T. Olivry n , J. Cullen  n, J. Salmon n & B. Gilger n 

Contributors: D. Pate n, A. Clode n, T. Olivry n , J. Cullen  n, J. Salmon n & B. Gilger n 

TL;DR: Pathogenesis of superficial stromal immune-mediated keratitis included cell-mediated inflammation governed by both cytotoxic and helper T cells and local immunoglobulins were present in affected corneas; however, corneal-binding immunoglolins were not detected in the serum or AH from horses with IMMK. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2012 journal article

Phacoemulsification and +14 diopter intraocular lens placement in a Saddlebred foal

VETERINARY OPHTHALMOLOGY, 16(2), 140–148.

By: J. Harrington n, R. McMullen  n, A. Clode n & B. Gilger n 

author keywords: cataract; equine phacoemulsification; foal; intraocular lens; ocular ultrasound; retinoscopy
MeSH headings : Animals; Cataract / pathology; Cataract / therapy; Cataract / veterinary; Cataract Extraction / methods; Cataract Extraction / veterinary; Female; Horse Diseases / surgery; Horse Diseases / therapy; Horses; Lens Implantation, Intraocular / veterinary; Phacoemulsification / veterinary
TL;DR: A +14 diopter (D) intraocular lens (IOL) IOL may be the appropriate choice following lens extraction in a foal to achieve refraction near emmetropia at maturity at maturity. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

A retrospective comparison of surgical removal and subsequent CO2 laser ablation versus topical administration of mitomycin C as therapy for equine corneolimbal squamous cell carcinoma

VETERINARY OPHTHALMOLOGY, 15(4), 254–262.

By: A. Clode n, C. Miller, R. McMullen  n & B. Gilger n 

author keywords: cornea; equine; mitomycin; squamous cell carcinoma
MeSH headings : Administration, Topical; Animals; Antibiotics, Antineoplastic / administration & dosage; Antibiotics, Antineoplastic / therapeutic use; Carcinoma, Squamous Cell / drug therapy; Carcinoma, Squamous Cell / surgery; Carcinoma, Squamous Cell / veterinary; Eye Neoplasms / drug therapy; Eye Neoplasms / surgery; Eye Neoplasms / veterinary; Female; Horse Diseases / drug therapy; Horse Diseases / surgery; Horse Diseases / therapy; Horses; Lasers, Gas / therapeutic use; Male; Mitomycin / administration & dosage; Mitomycin / therapeutic use; Ophthalmologic Surgical Procedures / methods; Ophthalmologic Surgical Procedures / veterinary; Retrospective Studies
TL;DR: Horses receiving adjunctive topical MMC therapy were no more likely to experience tumor recurrence than were horses undergoing CO(2) laser ablation in the horses in this study. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Aqueous humor and plasma concentrations of a compounded 0.2% solution of terbinafine following topical ocular administration to normal equine eyes

Veterinary Ophthalmology, 14(1), 41–47.

By: A. Clode n, J. Davis n, G. Davidson n, J. Salmon n, H. Lafevers n & B. Gilger n 

author keywords: aqueous humor; equine; keratomycosis; terbinafine
MeSH headings : Absorption; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / analysis; Antifungal Agents / blood; Antifungal Agents / pharmacokinetics; Aqueous Humor / chemistry; Chromatography, High Pressure Liquid / veterinary; Cornea / metabolism; Female; Horses / metabolism; Male; Naphthalenes / administration & dosage; Naphthalenes / analysis; Naphthalenes / blood; Naphthalenes / pharmacokinetics; Ophthalmic Solutions; Terbinafine
TL;DR: Topical ocular administration of compounded 0.2% terbinafine solution does not result in detectable AH or plasma levels following administration to normal equine eyes, suggesting its use for deep corneal or intraocular fungal infections in equine ophthalmology may be limited. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2011 journal article

Diagnosis of intraocular lymphosarcoma in a dog by use of a polymerase chain reaction assay for antigen receptor rearrangement

Journal of the American Veterinary Medical Association, 238(5), 625–630.

By: D. Pate n, B. Gilger* , S. Suter* & A. Clode*

MeSH headings : Animals; Antineoplastic Agents / therapeutic use; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Eye Neoplasms / diagnosis; Eye Neoplasms / drug therapy; Eye Neoplasms / pathology; Eye Neoplasms / veterinary; Lymphoma, Non-Hodgkin / diagnosis; Lymphoma, Non-Hodgkin / drug therapy; Lymphoma, Non-Hodgkin / veterinary; Male; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Receptors, Antigen
TL;DR: In the dog of this report, intraocular lymphosarcoma was diagnosed via PARR performed on samples of aqueous humor and the immunophenotype of the neoplastic cells was determined by use of that diagnostic technique. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2010 journal article

Aqueous humor and plasma concentrations of ciprofloxacin and moxifloxacin following topical ocular administration in ophthalmologically normal horses

American Journal of Veterinary Research, 71(5), 564–569.

By: A. Clode n, J. Davis*, J. Salmon*, H. LaFevers & B. Gilger* 

MeSH headings : Administration, Oral; Administration, Topical; Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / blood; Anti-Infective Agents / metabolism; Aqueous Humor / metabolism; Aza Compounds / administration & dosage; Aza Compounds / blood; Aza Compounds / metabolism; Ciprofloxacin / administration & dosage; Ciprofloxacin / blood; Ciprofloxacin / metabolism; Female; Fluoroquinolones; Horses / blood; Horses / metabolism; Male; Moxifloxacin; Orchiectomy / veterinary; Quinolines / administration & dosage; Quinolines / blood; Quinolines / metabolism
TL;DR: Moxifloxacin was better able to penetrate healthy equine corneas and reach measurable AH concentrations than was ciprofloxacIn, suggesting moxif loxac in might be of greater value in the treatment of deep corneal or intraocular bacterial infections caused by susceptible organisms. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2010 journal article

CASE REPORT: Anomalous nasolacrimal openings in a 2-year-old Morgan filly

Veterinary Ophthalmology, 13(5), 339–342.

By: B. Gilger n , J. Histed n, D. Pate n, A. Clode n & R. McMullen n

author keywords: computed tomography; congenital; epiphora; equine; nasolacrimal duct
MeSH headings : Animals; Female; Horse Diseases / pathology; Horse Diseases / surgery; Horses / abnormalities; Nasolacrimal Duct / abnormalities; Nasolacrimal Duct / surgery
TL;DR: This case report describes the clinical, diagnostic, computed tomography findings, and surgical treatment of a 2-year-old Morgan filly with bilateral, proximal, and distal anomalous nasolacrimal duct openings. (via Semantic Scholar)
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Added: August 6, 2018

2010 journal article

Effect of three treatment protocols on acute ocular hypertension after phacoemulsification and aspiration of cataracts in dogs

Veterinary Ophthalmology, 13(1), 14–19.

By: M. Crasta, A. Clode n, R. McMullen  n, D. Pate n & B. Gilger n 

author keywords: carbachol; cataract; dogs; IOP; latanoprost; phacoemulsification
MeSH headings : Administration, Topical; Animals; Carbachol / therapeutic use; Cataract Extraction / adverse effects; Cataract Extraction / veterinary; Dog Diseases / drug therapy; Dog Diseases / prevention & control; Dog Diseases / surgery; Dogs; Intraocular Pressure / drug effects; Latanoprost; Ocular Hypertension / etiology; Ocular Hypertension / prevention & control; Ocular Hypertension / veterinary; Phacoemulsification / adverse effects; Phacoemulsification / veterinary; Postoperative Period; Prostaglandins F, Synthetic / therapeutic use; Retrospective Studies
TL;DR: Topical 0.005% latanoprost or intracameral injection after PA in dogs did not reduce POH or increase intraocular inflammation compared to dogs not receiving adjunctive therapy after PA of cataracts. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2010 journal article

Long-term outcome after implantation of a suprachoroidal cyclosporine drug delivery device in horses with recurrent uveitis

Veterinary Ophthalmology, 13(5), 294–300.

By: B. Gilger n , D. Wilkie *, A. Clode n, R. McMullen n, M. Utter, A. Komaromy *, D. Brooks*, J. Salmon n

author keywords: cyclosporine; equine; implant; recurrent uveitis
MeSH headings : Animals; Cyclosporine / administration & dosage; Cyclosporine / therapeutic use; Female; Horse Diseases / drug therapy; Horses; Immunosuppressive Agents / administration & dosage; Immunosuppressive Agents / therapeutic use; Infusion Pumps, Implantable / veterinary; Male; Uveitis / drug therapy; Uveitis / veterinary
TL;DR: The increased vision loss related to uveitis episode of inflammation in eyes after the likely depletion of CsA from the CSI suggests that a repeat CSI may be required at or before 48 months after surgery. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2009 journal article

Infrared digital imaging of the equine anterior segment

Veterinary Ophthalmology, 12(2), 125–131.

By: R. McMullen Jr., A. Clode n & B. Gilger n 

author keywords: anterior segment; corneal disease; digital infrared photography; equine; melanoma; equine ophthalmology
MeSH headings : Animals; Eye / anatomy & histology; Eye Diseases / diagnosis; Eye Diseases / veterinary; Horse Diseases / diagnosis; Horses / anatomy & histology; Infrared Rays; Ophthalmology / instrumentation; Ophthalmology / methods; Photography / instrumentation; Photography / methods; Photography / veterinary
TL;DR: In the equine eye, advantages of infrared digital photography include increased contrast of anterior segment images, identification and monitoring of pigmentary changes, and increased visualization of the anterior segment through a cloudy or edematous cornea. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2009 journal article

Surgical correction of severe strabismus and enophthalmos secondary to zygomatic arch fracture in a dog

Veterinary Ophthalmology, 12(2), 119–124.

By: K. Konrade n, A. Clode n, T. Michau n, S. Roe n , B. Trumpatori n, W. Krug n, B. Gilger n 

author keywords: dog; fracture; miniplate fixation; orbital rim
MeSH headings : Animals; Bone Plates / veterinary; Dog Diseases / surgery; Dogs; Enophthalmos / surgery; Enophthalmos / veterinary; Male; Strabismus / surgery; Strabismus / veterinary; Zygomatic Fractures / surgery; Zygomatic Fractures / veterinary
TL;DR: A grossly displaced segmental zygomatic arch fracture with marked ventro-lateral deviation of the left globe was diagnosed in a 3-month-old male German Shepherd dog following a bite injury and surgical correction achieved sufficient skeletal fixation for proper anatomical reduction of the globe. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2008 journal article

Epibulbar melanoma in a foal

Veterinary Ophthalmology, 11, 44–50.

By: R. McMullen  n, A. Clode*, A. Pandiri n, D. Malarkey*, T. Michau* & B. Gilger* 

author keywords: congenital; epibulbar; equine; melanoma; neoplasia
MeSH headings : Animals; Animals, Newborn; Choroid Neoplasms / pathology; Choroid Neoplasms / surgery; Choroid Neoplasms / veterinary; Eye Enucleation / methods; Eye Enucleation / veterinary; Eye Neoplasms / pathology; Eye Neoplasms / surgery; Eye Neoplasms / veterinary; Horse Diseases / pathology; Horse Diseases / surgery; Horses; Limbus Corneae; Macrophages / pathology; Male; Melanoma / pathology; Melanoma / surgery; Melanoma / veterinary; Pigment Epithelium of Eye / pathology; Treatment Outcome
TL;DR: Based on the sudden onset and rapid growth as well as the histological evidence of invasion, well-differentiated features, heavy pigmentation, and no apparent mitoses, this neoplasm was considered to be a low-grade malignant melanoma. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2008 journal article

Letter to the Editor

Veterinary Ophthalmology, 11(3), 207–207.

By: B. Gilger n , A. Clode n, T. Miller n & R. McMullen n

MeSH headings : Animals; Controlled Clinical Trials as Topic; Diagnostic Techniques, Ophthalmological / standards; Dog Diseases / diagnosis; Dogs; Evidence-Based Medicine; Glaucoma / diagnosis; Glaucoma / veterinary
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Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2006 journal article

Evaluation of concentration of voriconazole in aqueous humor after topical and oral administration in horses

American Journal of Veterinary Research, 67(2), 296–301.

By: A. Clode n, J. Davis*, J. Salmon*, T. Michau* & B. Gilger* 

MeSH headings : Administration, Oral; Administration, Topical; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / adverse effects; Antifungal Agents / blood; Antifungal Agents / pharmacokinetics; Aqueous Humor / chemistry; Dose-Response Relationship, Drug; Female; Horses / metabolism; Male; Pyrimidines / administration & dosage; Pyrimidines / adverse effects; Pyrimidines / blood; Pyrimidines / pharmacokinetics; Triazoles / administration & dosage; Triazoles / adverse effects; Triazoles / blood; Triazoles / pharmacokinetics; Voriconazole
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

journal article

Impact of fungal species cultured on outcome in horses with fungal keratitis

Sherman, A. B., Clode, A. B., & Gilger, B. C. Pferdeheilkunde, 33(4), 394–395.

By: A. Sherman, A. Clode & B. Gilger 

Source: NC State University Libraries
Added: August 6, 2018

journal article

Treatment of immune-mediated keratitis in horses with episcleral cyclosporine-silicone matrix- implant

Gilger, B. C., Stoppini, R., Wilkie, D. A., Clode, A. B., Pinto, N. H., Hempstead, J., … Salmon, J. H. Pferdeheilkunde, 30(6), 711–712.

By: B. Gilger , R. Stoppini, D. Wilkie, A. Clode, N. Pinto, J. Hempstead, J. Gerding, J. Salmon

Source: NC State University Libraries
Added: August 6, 2018

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