Andrew James Loder

Works (9)

Updated: August 9th, 2023 15:05
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2019 journal article

Determinants of sulphur chemolithoautotrophy in the extremely thermoacidophilic Sulfolobales

ENVIRONMENTAL MICROBIOLOGY, 21(10), 3696–3710.

By: B. Zeldes n, A. Loder n, J. Counts n, M. Haque n, K. Widney  n, L. Keller  n, S. Albers *, R. Kelly n 

MeSH headings : Autotrophic Processes; Chemoautotrophic Growth; Oxidation-Reduction; Oxidoreductases / metabolism; Sulfolobales / metabolism; Sulfur / metabolism; Thiosulfates / metabolism
Sources: Web Of Science, ORCID
Added: August 12, 2019

2017 journal article

Impact of growth mode, phase, and rate on the metabolic state of the extremely thermophilic archaeon Pyrococcus furiosus

BIOTECHNOLOGY AND BIOENGINEERING, 114(12), 2947–2954.

By: P. Khatibi n, C. Chou n, A. Loder n, J. Zurawski n, M. Adams * & R. Kelly n 

author keywords: continuous culture; growth phase; growth rate; hyperthermophiles; Pyrococcus furiosus; transcriptome
MeSH headings : Archaeal Proteins / metabolism; Batch Cell Culture Techniques / methods; Cell Proliferation / physiology; Energy Metabolism / physiology; Pyrococcus furiosus / growth & development; Pyrococcus furiosus / metabolism; Transcriptome / physiology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Ancillary contributions of heterologous biotin protein ligase and carbonic anhydrase for CO2 incorporation into 3-hydroxypropionate by metabolically engineered Pyrococcus furiosus

Biotechnology and Bioengineering, 113(12), 2652–2660.

By: H. Lian, B. Zeldes, G. Lipscomb, A. Hawkins, Y. Han, A. Loder, D. Nishiyama, M. Adams, R. Kelly

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Reaction kinetic analysis of the 3-hydroxypropionate/4-hydroxybutyrate CO2 fixation cycle in extremely thermoacidophilic archaea

METABOLIC ENGINEERING, 38, 446–463.

By: A. Loder n, Y. Han n, A. Hawkins n, H. Lian n, G. Lipscomb*, G. Schut *, M. Keller *, M. Adams *, R. Kelly n 

author keywords: CO2 fixation; 3-hydroxypropionate; 4-hydroxybutyrate; Metallosphaera sedula
MeSH headings : Archaea / metabolism; Carbon Dioxide / metabolism; Extremophiles / metabolism; Hydroxybutyrates / metabolism; Kinetics; Lactic Acid / analogs & derivatives; Lactic Acid / metabolism; Metabolic Clearance Rate; Metabolic Flux Analysis / methods; Metabolic Networks and Pathways / physiology; Models, Biological; Signal Transduction / physiology; Sulfolobaceae / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

A hybrid synthetic pathway for butanol production by a hyperthermophilic microbe

METABOLIC ENGINEERING, 27, 101–106.

By: M. Keller *, G. Lipscomb*, A. Loder n, G. Schut *, R. Kelly n  & M. Adams *

author keywords: Butanol; Biofuels; Hyperthermophile; Module; Hybrid; Pathway
MeSH headings : 1-Butanol / metabolism; Acetyl Coenzyme A / genetics; Acetyl Coenzyme A / metabolism; Metabolic Engineering / methods; Thermoanaerobacterium / genetics; Thermoanaerobacterium / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

A mutant ('lab strain') of the hyperthermophilic archaeon Pyrococcus furiosus, lacking flagella, has unusual growth physiology

EXTREMOPHILES, 19(2), 269–281.

By: D. Lewis n, J. Notey n, S. Chandrayan *, A. Loder n, G. Lipscomb*, M. Adams *, R. Kelly n 

author keywords: Pyrococcus furiosus; Hyperthermophile; Archaeon; Growth physiology; Flagella
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Alcohol Selectivity in a Synthetic Thermophilic n-Butanol Pathway Is Driven by Biocatalytic and Thermostability Characteristics of Constituent Enzymes

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 81(20), 7187–7200.

By: A. Loder n, B. Zeldes n, G. Garrison n, G. Lipscomb*, M. Adams * & R. Kelly n 

MeSH headings : 1-Butanol / metabolism; Acetyl-CoA C-Acyltransferase / metabolism; Acyl Coenzyme A / metabolism; Alcohol Dehydrogenase / metabolism; Alcohol Oxidoreductases / metabolism; Aldehyde Oxidoreductases / metabolism; Biocatalysis; Chromatography, Gas; Clostridium acetobutylicum / metabolism; Clostridium thermocellum / metabolism; Thermoanaerobacter / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Bioprocessing analysis of Pyrococcus furiosus strains engineered for CO2-based 3-hydroxypropionate production

BIOTECHNOLOGY AND BIOENGINEERING, 112(8), 1533–1543.

By: A. Hawkins n, H. Lian n, B. Zeldes n, A. Loder n, G. Lipscomb*, G. Schut *, M. Keller *, M. Adams *, R. Kelly n 

author keywords: 3-hydroxypropionate; CO2 fixation; Metallosphaera sedula; Pyrococcus furiosus
MeSH headings : Bioreactors / microbiology; Carbon Dioxide / metabolism; Gene Expression Profiling; Hot Temperature; Lactic Acid / analogs & derivatives; Lactic Acid / metabolism; Maltose / metabolism; Metabolic Engineering / methods; Metabolic Networks and Pathways / genetics; Pyrococcus furiosus / genetics; Pyrococcus furiosus / metabolism; Pyrococcus furiosus / radiation effects; Sulfolobaceae / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 review

Extremely thermophilic microorganisms as metabolic engineering platforms for production of fuels and industrial chemicals

[Review of ]. FRONTIERS IN MICROBIOLOGY, 6.

By: B. Zeldes n, M. Keller *, A. Loder n, C. Straub n, M. Adams * & R. Kelly n 

author keywords: extreme thermophiles; metabolic engineering; bio-based chemicals; genetics; biotechnology
Sources: Web Of Science, ORCID
Added: August 6, 2018