Nancy Lynn Allbritton

Hyperglycemia minimally alters primary self-renewing human colonic epithelial cells while TNF alpha-promotes severe intestinal epithelial dysfunction

INTEGRATIVE BIOLOGY, 13(6), 139–152.

Magnetically-propelled fecal surrogates for modeling the impact of solid-induced shear forces on primary colonic epithelial cells

BIOMATERIALS, 276.

Stem/Proliferative and Differentiated Cells within Primary Murine Colonic Epithelium Display Distinct Intracellular Free Ca2+ Signal Codes

Mestril, S., Kim, R., Hinman, S. S., Gomez, S. M., & Allbritton, N. L. (2021, September 12). ADVANCED HEALTHCARE MATERIALS.

An in vitro intestinal platform with a self-sustaining oxygen gradient to study the human gut/microbiome interface

BIOFABRICATION, 12(1).

Assay and Isolation of Single Proliferating CD4+Lymphocytes Using an Automated Microraft Array Platform

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 67(8), 2166–2175.

Automated platform for cell selection and separation based on four-dimensional motility and matrix degradation

ANALYST, 145(7), 2731–2742.

Image-Based Live Cell Sorting

[Review of ]. TRENDS IN BIOTECHNOLOGY, 39(6), 613–623.

Microraft array-based platform for sorting of viable microcolonies based on cell-lethal immunoassay of intracellular proteins in microcolony biopsies

ANALYST, 145(7), 2649–2660.

Pooled CRISPR screens with imaging on microraft arrays reveals stress granule-regulatory factors

NATURE METHODS, 17(6), 636-+.

Preserving single cells in space and time for analytical assays

[Review of ]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 122.

"Fix and assay": separating in-cellulo sphingolipid reactions from analytical assay in time and space using an aldehyde-based fixative

ANALYST, 144(3), 961–971.

Automated sensing and splitting of stem cell colonies on microraft arrays

APL BIOENGINEERING, 3(3).

Building a Thick Mucus Hydrogel Layer to Improve the Physiological Relevance of In Vitro Primary Colonic Epithelial Models

Evaluation of human primary intestinal monolayers for drug metabolizing capabilities

JOURNAL OF BIOLOGICAL ENGINEERING, 13(1).

Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking

JOURNAL OF BIOLOGICAL ENGINEERING, 13.

Photopatterned Membranes and Chemical Gradients Enable Scalable Phenotypic Organization of Primary Human Colon Epithelial Models

ANALYTICAL CHEMISTRY, 91(23), 15240–15247.

Primary Cell-Derived Intestinal Models: Recapitulating Physiology

[Review of ]. TRENDS IN BIOTECHNOLOGY, 37(7), 744–760.

Selection and optimization of enzyme reporters for chemical cytometry

CHEMICAL AND SYNTHETIC BIOLOGY APPROACHES TO UNDERSTAND CELLULAR FUNCTIONS - PT B, Vol. 622, pp. 221–248.

A Monolayer of Primary Colonic Epithelium Generated on a Scaffold with a Gradient of Stiffness for Drug Transport Studies

ANALYTICAL CHEMISTRY, 90(22), 13331–13340.

Analysis of Interleukin 8 Secretion by a Stem-Cell-Derived Human-Intestinal-Epithelial-Monolayer Platform

ANALYTICAL CHEMISTRY, 90(19), 11523–11530.

Bioengineered systems and designer matrices that recapitulate the intestinal stem cell niche

[Review of ]. Cellular and Molecular Gastroenterology and Hepatology, 5(3), 440-.

Characterization of Tensioned PDMS Membranes for Imaging Cytometry on Microraft Arrays

ANALYTICAL CHEMISTRY, 90(7), 4792–4800.

Formation of Human Colonic Crypt Array by Application of Chemical Gradients Across a Shaped Epithelial Monolayer

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 5(2), 113–130.

LITE microscopy: Tilted light-sheet excitation of model organisms offers high resolution and low photobleaching

JOURNAL OF CELL BIOLOGY, 217(5), 1869–1882.

N-Gemini peptides: cytosolic protease resistance via N-terminal dimerization of unstructured peptides

CHEMICAL COMMUNICATIONS, 54(2), 204–207.

Nonsteroidal Anti-Inflammatory Drug -Induced Leaky Gut Modeled Using Polarized Monolayers of Primary Human Intestinal Epithelial Cells

ACS INFECTIOUS DISEASES, 4(1), 46–52.

A microengineered collagen scaffold for generating a polarized crypt-villus architecture of human small intestinal epithelium

BIOMATERIALS, 128, 44–55.

Automated microraft platform to identify and collect non-adherent cells successfully gene-edited with CRISPR-Cas9

BIOSENSORS & BIOELECTRONICS, 91, 175–182.

Chemical fixation to arrest phospholipid signaling for chemical cytometry

JOURNAL OF CHROMATOGRAPHY A, 1523, 97–106.

Required hydrophobicity of fluorescent reporters for phosphatidylinositol family of lipid enzymes

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 409(29), 6781–6789.

Self-renewing monolayer of primary colonic or rectal epithelial cells

Cellular and Molecular Gastroenterology and Hepatology, 4(1), 165-.

An Integrated Chemical Cytometry Method: Shining a Light on Akt Activity in Single Cells

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 55(42), 13095–13098.

Co-fabrication of chitosan and epoxy photoresist to form microwell arrays with permeable hydrogel bottoms

BIOMATERIALS, 74, 77–88.

Development of a protease-resistant reporter to quantify BCR-ABL activity in intact cells

ANALYST, 141(21), 6008–6017.

Identification and isolation of antigen-specific cytotoxic T lymphocytes with an automated microraft sorting system

INTEGRATIVE BIOLOGY, 8(12), 1208–1220.

In vitro polarization of colonoids to create an intestinal stem cell compartment

PLoS One, 11(4).

Rational Design of a Dephosphorylation-Resistant Reporter Enables Single-Cell Measurement of Tyrosine Kinase Activity

ACS CHEMICAL BIOLOGY, 11(2), 355–362.

Single Cell Chemical Cytometry of Akt Activity in Rheumatoid Arthritis and Normal Fibroblast-like Synoviocytes in Response to Tumor Necrosis Factor alpha

ANALYTICAL CHEMISTRY, 88(15), 7786–7792.

Single-cell functional analysis of parathyroid adenomas reveals distinct classes of calcium sensing behaviour in primary hyperparathyroidism

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 20(2), 351–359.

Analysis of sphingosine kinase activity in single natural killer cells from peripheral blood

INTEGRATIVE BIOLOGY, 7(4), 392–401.

Array-Based Platform To Select, Release, and Capture Epstein-Barr Virus-Infected Cells Based on Intercellular Adhesion

ANALYTICAL CHEMISTRY, 87(24), 12281–12289.

Magnetic Alignment of Microelements Containing Cultured Neuronal Networks for High-Throughput Screening

JOURNAL OF BIOMOLECULAR SCREENING, 20(9), 1091–1100.

Optimizing Wnt-3a and R-spondin1 concentrations for stem cell renewal and differentiation in intestinal organoids using a gradient-forming microdevice

RSC ADVANCES, 5(91), 74881–74891.

Pronase E-Based Generation of Fluorescent Peptide Fragments: Tracking Intracellular Peptide Fate in Single Cells

ANALYTICAL CHEMISTRY, 87(15), 7987–7995.

Separation of peptide fragments of a protein kinase C substrate fused to a beta-hairpin by capillary electrophoresis

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 407(30), 8999–9008.

An Immature Retroviral RNA Genome Resembles a Kinetically Trapped Intermediate State

JOURNAL OF VIROLOGY, 88(11), 6061–6068.

Dynamics and evolution of beta-catenin-dependent Wnt signaling revealed through massively parallel clonogenic screening

INTEGRATIVE BIOLOGY, 6(7), 673–684.

Ex Vivo Chemical Cytometric Analysis of Protein Tyrosine Phosphatase Activity in Single Human Airway Epithelial Cells

ANALYTICAL CHEMISTRY, 86(2), 1291–1297.

Measurement of Protein Kinase B Activity in Single Primary Human Pancreatic Cancer Cells

ANALYTICAL CHEMISTRY, 86(9), 4573–4580.

Micropallet arrays for the capture, isolation and culture of circulating tumor cells from whole blood of mice engrafted with primary human pancreatic adenocarcinoma

BIOSENSORS & BIOELECTRONICS, 54, 476–483.

Response of single leukemic cells to peptidase inhibitor therapy across time and dose using a microfluidic device

INTEGRATIVE BIOLOGY, 6(2), 164–174.

Single-cell sphingosine kinase activity measurements in primary leukemia

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 406(27), 7027–7036.

Small Sample Sorting of Primary Adherent Cells by Automated Micropallet Imaging and Release

CYTOMETRY PART A, 85A(7), 642–649.

A comparative analysis of the ubiquitination kinetics of multiple degrons to identify an ideal targeting sequence for a proteasome reporter

PLoS One, 8(10).

Array of biodegradable microrafts for isolation and implantation of living, adherent cells

RSC Advances, 3(24), 9264–9272.

Automated Capillary Electrophoresis System for Fast Single-Cell Analysis

ANALYTICAL CHEMISTRY, 85(9), 4797–4804.

Capture and 3D culture of colonic crypts and colonoids in a microarray platform

Lab on a Chip, 13(23), 4625–4634.

Characterization of freestanding photoresist films for biological and MEMS applications

Journal of Micromechanics and Microengineering, 23(2).

Efficient division and sampling of cell colonies using microcup arrays

ANALYST, 138(1), 220–228.

Fabrication of 3D Microstructures from Interactions of Immiscible Liquids with a Structured Surface

ADVANCED MATERIALS, 25(30), 4107–4112.

Isolation and in Vitro Culture of Rare Cancer Stem Cells from Patient-Derived Xenografts of Pancreatic Ductal Adenocarcinoma

ANALYTICAL CHEMISTRY, 85(15), 7271–7278.

Laser-based directed release of array elements for efficient collection into targeted microwells

ANALYST, 138(3), 831–838.

Measurement of Protein Tyrosine Phosphatase Activity in Single Cells by Capillary Electrophoresis

ANALYTICAL CHEMISTRY, 85(12), 6136–6142.

Measuring Activity in the Ubiquitin-Proteasome System: From Large Scale Discoveries to Single Cells Analysis

CELL BIOCHEMISTRY AND BIOPHYSICS, 67(1), 75–89.

Micro Total Analysis Systems: Fundamental Advances and Applications in the Laboratory, Clinic, and Field

[Review of ]. ANALYTICAL CHEMISTRY, 85(2), 451–472.

Microfluidic Chemical Cytometry of Peptide Degradation in Single Drug-Treated Acute Myeloid Leukemia Cells

ANALYTICAL CHEMISTRY, 85(10), 4991–4997.

Scalable synthesis of a biocompatible, transparent and superparamagnetic photoresist for microdevice fabrication

Journal of Micromechanics and Microengineering, 23(10).

beta-Turn sequences promote stability of peptide substrates for kinases within the cytosolic environment

Analyst [London], 138(15), 4305–4311.

Development of a Peptidase-Resistant Substrate for Single-Cell Measurement of Protein Kinase B Activation

ANALYTICAL CHEMISTRY, 84(16), 7195–7202.

Dissolution-guided wetting for microarray and microfluidic devices

Lab on a Chip, 12(17), 3036–3039.

Metabolism of peptide reporters in cell lysates and single cells

Analyst [London], 137(13), 3028–3038.

Micro Total Analysis Systems for Cell Biology and Biochemical Assays

[Review of ]. ANALYTICAL CHEMISTRY, 84(2), 516–540.

Microfabricated Arrays for Splitting and Assay of Clonal Colonies

ANALYTICAL CHEMISTRY, 84(24), 10614–10620.

Polystyrene-coated micropallets for culture and separation of primary muscle cells

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 402(3), 1083–1091.

Separation of fluorescently labeled phosphoinositides and sphingolipids by capillary electrophoresis

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 907, 79–86.

Trapping cells on a stretchable microwell array for single-cell analysis

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 402(3), 1065–1072.

Trapping cells on a stretchable microwell array for single-cell analysis (vol 402, pg 1065, 2012)

Analytical and Bioanalytical Chemistry, Vol. 404, pp. 2519–2519.

Benchtop micromolding of polystyrene by soft lithography

Lab on a Chip, 11(18), 3089–3097.

Continuous analysis of dye-loaded, single cells on a microfluidic chip

Lab on a Chip, 11(7), 1333–1341.

Femtomole SHAPE Reveals Regulatory Structures in the Authentic XMRV RNA Genome

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133(50), 20326–20334.

Isolation and manipulation of living adherent cells by micromolded magnetic rafts

Biomicrofluidics, 5(3).

Kinetic analysis of PI3K reactions with fluorescent PIP2 derivatives

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 401(6), 1881–1888.

Measuring enzyme activity in single cells

[Review of ]. TRENDS IN BIOTECHNOLOGY, 29(5), 222–230.

Patterning pallet arrays for cell selection based on high-resolution measurements of fluorescent biosensors

ANALYTICA CHIMICA ACTA, 696(1-2), 101–107.

Sample transport and electrokinetic injection in a microchip device for chemical cytometry

ELECTROPHORESIS, 32(22), 3180–3187.

Selection and Separation of Viable Cells Based on a Cell-Lethal Assay

ANALYTICAL CHEMISTRY, 83(1), 278–283.

Single-cell analysis of phosphoinositide 3-kinase and phosphatase and tensin homolog activation

Faraday Discussions, 149, 187–200.

Use of a virtual wall valve in polydimethylsiloxane microfluidic devices for bioanalytical applications

Biomicrofluidics, 5(2).

Air-stable supported membranes for single-cell cytometry on PDMS microchips

Lab on a Chip, 10(7), 864–870.

Contact printing of arrayed microstructures

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 397(8), 3377–3385.

In situ Roughening of Polymeric Microstructures

ACS APPLIED MATERIALS & INTERFACES, 2(4), 1086–1093.

Microcup Arrays for the Efficient Isolation and Cloning of Cells

ANALYTICAL CHEMISTRY, 82(8), 3161–3167.

Microdevice to capture colon crypts for in vitro studies

Lab on a Chip, 10(12), 1596–1603.

Microelectrophoresis platform for fast serial analysis of single cells

Electrophoresis, 31(15), 2558–2565.

Micromolded arrays for separation of adherent cells

Lab on a Chip, 10(21), 2917–2924.

Microtable arrays for culture and isolation of cell colonies

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 398(6), 2595–2604.

Transparent magnetic photoresists for bioanalytical applications

BIOMATERIALS, 31(33), 8810–8817.