Works Published in 2008
Displaying works 41 - 60 of 95 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2008 conference paper
Addressing Non-uniqueness in a Water Distribution Contaminant Source Identification Problem
Water Distribution Systems Analysis Symposium 2006. Presented at the Eighth Annual Water Distribution Systems Analysis Symposium (WDSA).
Event: Eighth Annual Water Distribution Systems Analysis Symposium (WDSA)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020
2008 conference paper
Adaptive Contamination Source Identification in Water Distribution Systems Using an Evolutionary Algorithm-based Dynamic Optimization Procedure
Water Distribution Systems Analysis Symposium 2006. Presented at the Eighth Annual Water Distribution Systems Analysis Symposium (WDSA).
Event: Eighth Annual Water Distribution Systems Analysis Symposium (WDSA)
TL;DR:
A new multi population-based search using an evolutionary algorithm (EA) that at any time represents the solution state that best matches the available observations that is demonstrated for a contamination source identification problem in an illustrative water distribution network.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020
2008 journal article
Simultaneous fragmentation of multiple ions using IMS drift time dependent collision energies
Journal of the American Society For Mass Spectrometry, 19(3), 411–419.
Contributors: E. Baker* , K. Tang *, W. Danielson*, D. Prior* & R. Smith *
MeSH headings : Angiotensin I / chemistry; Bradykinin / chemistry; Electricity; Fibrinopeptide A / chemistry; Ions / chemistry; Neurotensin / chemistry; Peptides / chemistry; Serum Albumin, Bovine / chemistry; Spectrometry, Mass, Electrospray Ionization / instrumentation; Spectrometry, Mass, Electrospray Ionization / methods; Spectrum Analysis / methods; Trypsin / chemistry
TL;DR:
In conclusion, ion collision energy ramping technique that simultaneously fragments a variety of species and fragmentation efficiencies were found to be similar for different ions when the fragmentation voltage was linearly ramped with drift time, but varied drastically when only a single voltage was used.
(via Semantic Scholar)
link.springer.com (publisher PDF)
Source: ORCID
Added: December 5, 2019
2008 journal article
High-resolution separations and improved ion production and transmission in metabolomics
Trac-Trends in Analytical Chemistry, 27(3), 205–214.
author keywords: electrospray ionization; ion mobility spectroscopy; liquid chromatography; mass spectrometry; metabolomics
TL;DR:
The role of high resolution liquid chromatography separations in conjunction with improved ion production and transmission for LC-MS-based metabolomics will be focused on, with additional emphasis on the compromise between metabolome coverage and sample analysis throughput.
(via Semantic Scholar)
Source: ORCID
Added: December 5, 2019
2008 journal article
G-quadruplex DNA assemblies: Loop length, cation identity, and multimer formation
Journal of the American Chemical Society, 130(31), 10208–10216.
Contributors: N. Smargiasso*, F. Rosu *, W. Hsia*, P. Colson *, E. Baker* , M. Bowers *, E. De Pauw *, V. Gabelica *
MeSH headings : Base Sequence; Cations; Dimerization; G-Quadruplexes; Nucleic Acid Conformation; Oligodeoxyribonucleotides / chemistry
TL;DR:
It is found that sequences with short loops form very stable multimeric quadruplexes, even at low strand concentration, and the nature of the cation also has an influence on the adopted structures.
(via Semantic Scholar)
Source: ORCID
Added: December 5, 2019
2008 journal article
Pesticides and Atopic and Nonatopic Asthma among Farm Women in the Agricultural Health Study
American Journal of Respiratory and Critical Care Medicine, 177(1), 11–18.
Contributors: J. Hoppin* , D. Umbach *, S. London, P. Henneberger *, G. Kullman*, M. Alavanja*, D. Sandler
author keywords: agricultural workers; allergy; asthma; organophosphates; pesticides
MeSH headings : Adult; Agricultural Workers' Diseases / epidemiology; Agricultural Workers' Diseases / prevention & control; Asthma / epidemiology; Asthma / prevention & control; Causality; Cohort Studies; Cross-Sectional Studies; Dermatitis, Atopic / epidemiology; Dermatitis, Atopic / prevention & control; Female; Humans; Iowa; Middle Aged; North Carolina; Occupational Exposure / adverse effects; Pesticides / adverse effects; Regression Analysis; Respiratory Hypersensitivity / epidemiology; Respiratory Hypersensitivity / prevention & control; Rhinitis, Allergic, Seasonal / epidemiology; Rhinitis, Allergic, Seasonal / prevention & control; Risk Factors
TL;DR:
It is suggested that pesticides may contribute to atopic asthma, but not nonatopic allergy, among farm women.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
S -Ethyl- N,N -dipropylthiocarbamate Exposure and Cancer Incidence among Male Pesticide Applicators in the Agricultural Health Study: A Prospective Cohort
Environmental Health Perspectives, 116(11), 1541–1546.
Contributors: D. Bemmel *, K. Visvanathan *, L. Beane Freeman*, J. Coble*, J. Hoppin* & M. Alavanja*
author keywords: agriculture; cancer; EPTC; herbicide; neoplasms; occupational exposure; pesticides; thiocarbamates
MeSH headings : Adult; Agricultural Workers' Diseases; Cohort Studies; Herbicides / toxicity; Humans; Incidence; Iowa / epidemiology; Male; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; North Carolina / epidemiology; Thiocarbamates / toxicity
TL;DR:
In this analysis, EPTC use appeared to be associated with colon cancer and leukemia, however, given the relatively small number of cases in the highest exposure tertile, results should be interpreted with caution, and further investigations are needed.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Meat and Meat Mutagens and Risk of Prostate Cancer in the Agricultural Health Study
Cancer Epidemiology Biomarkers & Prevention, 17(1), 80–87.
Contributors: S. Koutros *, A. Cross *, D. Sandler *, J. Hoppin* , X. Ma *, T. Zheng *, M. Alavanja*, R. Sinha *
MeSH headings : Case-Control Studies; Cohort Studies; Cooking; Diet; Humans; Male; Meat; Middle Aged; Mutagens / adverse effects; Polycyclic Aromatic Hydrocarbons / adverse effects; Prospective Studies; Prostatic Neoplasms / epidemiology; Prostatic Neoplasms / etiology; Quinoxalines / adverse effects
TL;DR:
In conclusion, well and very well done meat was associated with an increased risk for prostate cancer in this cohort.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Dichlorvos exposure and human cancer risk: Results from the Agricultural Health Study
Cancer Causes and Control, 19(1), 59–65.
Contributors: S. Koutros *, R. Mahajan*, T. Zheng *, J. Hoppin* , X. Ma *, C. Lynch *, A. Blair*, M. Alavanja*
author keywords: pesticides; organophosphate insecticides; dichlorvos (DDVP); prospective cohort; cancer etiology
MeSH headings : Adult; Agricultural Workers' Diseases / chemically induced; Agricultural Workers' Diseases / epidemiology; Agriculture; Dichlorvos / adverse effects; Female; Humans; Insecticides / adverse effects; Male; Middle Aged; Neoplasms / chemically induced; Neoplasms / epidemiology; Occupational Exposure / adverse effects; Risk Factors
TL;DR:
There is little evidence of an association between cumulative lifetime use of DDVP and risk of any cancer at this stage of follow up of the AHS, and DDVP exposure was not associated with any cancer studied here.
(via Semantic Scholar)
Source: ORCID
Added: September 13, 2019
2008 journal article
An interlaboratory study of perfluorinated alkyl compound levels in human plasma
Environmental Research, 107(2), 152–159.
Contributors: M. Longnecker*, C. Smith *, G. Kissling*, J. Hoppin* , J. Butenhoff*, E. Decker*, D. Ehresman*, M. Ellefson*
author keywords: perfluorinated alkyl compounds; interlaboratory study; persistent organic pollutants; interdisciplinary studies; research design; epidemiologic methods
MeSH headings : Adult; Biomarkers / blood; Environmental Monitoring / standards; Environmental Pollutants / analysis; Female; Fluorocarbons / blood; Humans; Male; Pregnancy
TL;DR:
Considering the degree of between-subject variation in levels among people in background-exposed populations, the results indicate that biomarker-based epidemiologic studies of associations with health could have reasonable precision.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Cancer incidence among pesticide applicators exposed to trifluralin in the Agricultural Health Study
Environmental Research, 107(2), 271–276.
Contributors: D. Kang *, S. Park *, L. Beane-Freeman *, C. Lynch *, C. Knott*, D. Sandler *, J. Hoppin* , M. Dosemeci*
author keywords: agriculture; trifluralin; pesticides; cancer; occupational exposure
MeSH headings : Adult; Agriculture; Female; Herbicides / toxicity; Humans; Incidence; Male; Middle Aged; Neoplasms / epidemiology; Neoplasms / etiology; Occupational Exposure; Prospective Studies; Trifluralin / toxicity; United States
TL;DR:
Although there was a possible link between trifluralin exposure and colon cancer, small numbers and inconsistencies in dose-response and subgroup analyses indicate that this may be a chance finding.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Hearing Loss Among Licensed Pesticide Applicators in the Agricultural Health Study
Journal of Occupational and Environmental Medicine, 50(7), 817–826.
Contributors: J. Crawford, J. Hoppin* , M. Alavanja, A. Blair, D. Sandler & F. Kamel
MeSH headings : Adult; Agriculture; Commerce; Health Surveys; Hearing Loss / chemically induced; Hearing Loss / epidemiology; Humans; Licensure; Male; Middle Aged; North Carolina / epidemiology; Occupational Exposure; Odds Ratio; Organophosphates; Pesticides / adverse effects
TL;DR:
Although control for exposure to noise or other neurotoxicants was limited, this study extends previous reports suggesting that organophosphate exposure increases risk of hearing loss.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Chlorothalonil exposure and cancer incidence among pesticide applicator participants in the agricultural health study
Environmental Research, 108(3), 400–403.
Contributors: A. Mozzachio*, J. Rusiecki *, J. Hoppin* , R. Mahajan*, R. Patel*, L. Beane-Freeman *, M. Alavanja*
author keywords: Chlorothalonil; Pesticides; Fungicides; Cancer; Agriculture
MeSH headings : Agriculture / statistics & numerical data; Cohort Studies; Fungicides, Industrial / toxicity; Humans; Neoplasms / chemically induced; Neoplasms / epidemiology; Nitriles / toxicity; North Carolina / epidemiology; Occupational Exposure / analysis; Prospective Studies
TL;DR:
Chlorothalonil was not associated with overall cancer incidence, nor did the authors find any association with colon, lung, and prostate cancers--the only cancers for which they had sufficient numbers to explore associations.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Evaluation of Freeze–Thaw Cycles on Stored Plasma in the Biobank of the Norwegian Mother and Child Cohort Study
Cell Preservation Technology, 6(3), 223–229.
Contributors: L. Paltiel*, K. Rønningen *, H. Meltzer *, S. Baker* & J. Hoppin*
TL;DR:
Human plasma can go through several freeze-thaw cycles before analysis without influencing sample integrity for the selected analytes, according to a quality control study using pooled EDTA-plasma.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Cancer incidence among pesticide applicators exposed to captan in the Agricultural Health Study
Cancer Causes & Control, 19(10), 1401–1407.
Contributors: D. Greenburg*, J. Rusiecki *, S. Koutros *, M. Dosemeci*, R. Patel*, C. Hines*, J. Hoppin* , M. Alavanja*
author keywords: Captan; Cancer; Agricultural Health Study; Cohort; Prospective; Pesticide; Fungicide; CAS number 133-06-2
MeSH headings : Adult; Agricultural Workers' Diseases / epidemiology; Captan / adverse effects; Cohort Studies; Confidence Intervals; Follow-Up Studies; Fungicides, Industrial / adverse effects; Humans; Incidence; Iowa / epidemiology; Life Style; Male; Middle Aged; Neoplasms / classification; Neoplasms / epidemiology; Neoplasms / etiology; North Carolina / epidemiology; Occupational Exposure / adverse effects; Poisson Distribution; Prevalence; Prospective Studies; Risk Factors; Surveys and Questionnaires; Time Factors
TL;DR:
This study is limited by low numbers of observed cancer cases and follow-up time, it does not provide evidence of an increased risk for the development of cancer at the investigated sites, and no association between the highest tertile of captan exposure and development of all cancers was observed.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
Depression and Pesticide Exposures among Private Pesticide Applicators Enrolled in the Agricultural Health Study
Environmental Health Perspectives, 116(12), 1713–1719.
Contributors: C. Beseler *, L. Stallones *, J. Hoppin* , M. Alavanja*, A. Blair*, T. Keefe*, F. Kamel*
author keywords: cumulative exposure; depression; farm applicators; pesticides; pesticide poisoning
MeSH headings : Adult; Agriculture; Depression / chemically induced; Humans; Iowa; Middle Aged; North Carolina; Occupational Exposure; Pesticides / toxicity; Surveys and Questionnaires
TL;DR:
This study is unique in reporting that depression is also associated with chronic pesticide exposure in the absence of a physician-diagnosed poisoning.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019
2008 journal article
An Evaluation of Information Content as a Metric for the Inference of Putative Conserved Noncoding Regions in DNA Sequences Using a Genetic Algorithms Approach
IEEE/ACM Transactions on Computational Biology and Bioinformatics, 5(1), 1–14.
author keywords: evolutionary computing; genetic algorithms; biology; genetics
MeSH headings : Algorithms; Animals; Base Sequence; Computational Biology / methods; Confidence Intervals; Conserved Sequence / genetics; Cystic Fibrosis Transmembrane Conductance Regulator / genetics; Enhancer Elements, Genetic / genetics; Glutathione Transferase / genetics; Humans; Models, Genetic; Regulatory Sequences, Nucleic Acid / genetics; Sequence Alignment; Sequence Analysis, DNA / methods; Sex-Determining Region Y Protein / genetics
TL;DR:
Results indicate that IC does not identify highly conserved regions and, thus, is not the appropriate metric for this task, whereas variations on IC, as well as the original metric, succeed in identifying putative Conserved regions.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 10, 2019
2008 journal article
The Comparative Toxicogenomics Database facilitates identification and understanding of chemical-gene-disease associations: arsenic as a case study
BMC Medical Genomics, 1(1).
TL;DR:
Analysis of curated data for the chemical arsenic provides insight into the biological functions and molecular networks affected by exposure to arsenic, including stress response, apoptosis, cell cycle, and specific protein signaling pathways.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 10, 2019
2008 journal article
A critical role for DAP10 and DAP12 in CD8+ T cell-mediated tissue damage in large granular lymphocyte leukemia
Blood, 113(14), 3226–3234.
MeSH headings : Adaptor Proteins, Signal Transducing / genetics; Adaptor Proteins, Signal Transducing / metabolism; Adaptor Proteins, Signal Transducing / physiology; CD28 Antigens / metabolism; CD8-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / metabolism; CD8-Positive T-Lymphocytes / pathology; Cytotoxicity, Immunologic / genetics; Endothelial Cells / immunology; Endothelial Cells / pathology; Extracellular Signal-Regulated MAP Kinases / metabolism; Humans; K562 Cells; Leukemia, Large Granular Lymphocytic / genetics; Leukemia, Large Granular Lymphocytic / immunology; Leukemia, Large Granular Lymphocytic / metabolism; Leukemia, Large Granular Lymphocytic / pathology; Membrane Proteins / genetics; Membrane Proteins / metabolism; Membrane Proteins / physiology; Phosphatidylinositol 3-Kinases / metabolism; Pulmonary Artery / immunology; Pulmonary Artery / pathology; Receptors, Immunologic / genetics; Receptors, Immunologic / metabolism; Receptors, Immunologic / physiology; Receptors, Natural Killer Cell / metabolism; Signal Transduction / genetics; Tumor Cells, Cultured
TL;DR:
Results shown suggest that inhibitors of DAP10 and DAP12 or other proteins involved in this signaling pathway will be attractive therapeutic targets for the treatment of LGLL and other autoimmune diseases and syndromes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: NC State University Libraries, Crossref
Added: May 17, 2019
2008 journal article
Genetic basis for adverse events after smallpox vaccination.
Journal of Infectious Diseases, 198(1), 16–22.
Contributors: D. Reif* , B. McKinney *, A. Motsinger*, S. Chanock *, K. Edwards *, M. Rock*, J. Moore, J. Crowe Jr.
MeSH headings : Adult; Female; Genetic Predisposition to Disease; Genotype; Humans; Interferon Regulatory Factor-1 / genetics; Interleukin-4 / genetics; Male; Methylenetetrahydrofolate Reductase (NADPH2) / genetics; Polymorphism, Single Nucleotide; Smallpox Vaccine / adverse effects; Vaccination / adverse effects
TL;DR:
Genetic polymorphisms in genes expressing an enzyme previously associated with adverse reactions to a variety of pharmacologic agents (MTHFR) and an immunological transcription factor (IRF1) were associated with AEs after smallpox vaccination in 2 independent study samples.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: May 14, 2019
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