Lloyd Norman Fleisher

Works (43)

Updated: July 28th, 2023 21:14

2017 journal article

Vitreous Humor Changes Expression of Iron-Handling Proteins in Lens Epithelial Cells

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 58(2).

By: M. Goralska n, L. Fleisher n & M. McGahan n

author keywords: iron; oxidative damage; ferritin; transferrin receptor; vitreous humor
MeSH headings : Animals; Aquaporins / metabolism; Blotting, Western; Cells, Cultured; Disease Models, Animal; Dogs; Epithelial Cells / metabolism; Eye Proteins / metabolism; Ferritins / metabolism; Immunohistochemistry; Lens, Crystalline / metabolism; Receptors, Transferrin / metabolism; Vitreous Body / physiology
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Hypoxia induced changes in expression of proteins involved in iron uptake and storage in cultured lens epithelial cells

EXPERIMENTAL EYE RESEARCH, 125, 135–141.

By: M. Goralska n, L. Fleisher n & M. McGahan n

author keywords: lens; iron; iron proteins; hypoxia
MeSH headings : Animals; Cell Hypoxia / physiology; Cells, Cultured; Dogs; Epithelial Cells / metabolism; Ferritins / metabolism; Gene Expression Regulation; Lens, Crystalline / cytology; Lens, Crystalline / metabolism; Oxidative Stress / physiology; RNA, Messenger / metabolism; Real-Time Polymerase Chain Reaction; Receptors, Transferrin / metabolism; Transferrin / metabolism
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Source-Dependent Intracellular Distribution of Iron in Lens Epithelial Cells Cultured Under Normoxic and Hypoxic Conditions

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 54(12), 7666–7673.

By: M. Goralska n, S. Nagar*, L. Fleisher*, P. Mzyk* & M. McGahan

author keywords: iron trafficking; transferrin; NTBI; lens epithelial cells; hypoxia
MeSH headings : Animals; Biological Transport; Cell Nucleus / metabolism; Cell Proliferation; Cell Survival; Cells, Cultured; Chlorides / metabolism; Dogs; Epithelial Cells / metabolism; Ferric Compounds / metabolism; Hypoxia / metabolism; Intracellular Fluid / metabolism; Iron Radioisotopes / metabolism; Lens, Crystalline / cytology; Lens, Crystalline / metabolism; Mitochondria / metabolism; Transferrin / metabolism
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Ceruloplasmin alters intracellular iron regulated proteins and pathways: Ferritin, transferrin receptor, glutamate and hypoxia-inducible factor-1α

Experimental Eye Research, 97(1), 90–97.

By: J. Harned n, J. Ferrell n, S. Nagar n, M. Goralska n, L. Fleisher n & M. McGahan n

author keywords: ceruloplasmin; iron; lens epithelial cells; retinal pigmented epithelial cells glutamate; hypoxia-inducible factor; transferrin receptor; ferritin
MeSH headings : Animals; Cells, Cultured; Ceruloplasmin / metabolism; Ceruloplasmin / pharmacology; Dogs; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Ferritins / metabolism; Fluorescent Antibody Technique, Indirect; Glutamic Acid / metabolism; Hypoxia-Inducible Factor 1, alpha Subunit / metabolism; Iron Chelating Agents / pharmacology; Lens, Crystalline / cytology; Oxalates / pharmacology; Receptors, Transferrin / metabolism; Retinal Pigment Epithelium / drug effects; Retinal Pigment Epithelium / metabolism
Sources: Web Of Science, Crossref
Added: August 6, 2018

2010 journal article

Altered Ferritin Subunit Composition: Change in Iron Metabolism in Lens Epithelial Cells and Downstream Effects on Glutathione Levels and VEGF Secretion

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 51(9), 4437–4446.

By: J. Harned n, J. Ferrell n, M. Lall n, L. Fleisher n, S. Nagar n, M. Goralska n, M. McGahan n

MeSH headings : Animals; Apoferritins / genetics; Apoferritins / metabolism; Cell Nucleus / metabolism; Cells, Cultured; Culture Media, Conditioned / pharmacology; Cystine / pharmacokinetics; Dogs; Epithelial Cells / cytology; Epithelial Cells / metabolism; Glutathione / metabolism; Homeostasis / physiology; Hypoxia-Inducible Factor 1, alpha Subunit / metabolism; Iron / metabolism; Lens, Crystalline / cytology; Lens, Crystalline / metabolism; Oxidative Stress / physiology; Protein Subunits / genetics; Protein Subunits / metabolism; RNA, Small Interfering; Transfection; Vascular Endothelial Growth Factor A / metabolism
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Changes in Ferritin H- and L-Chains in Canine Lenses with Age-Related Nuclear Cataract

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 50(1), 305–310.

By: M. Goralska n, S. Nagar n, C. Colitz n, L. Fleisher n & M. McGahan n

MeSH headings : Aging; Animals; Apoferritins / metabolism; Cataract / metabolism; Cataract / veterinary; Dog Diseases / metabolism; Dogs; Electrophoresis, Polyacrylamide Gel / veterinary; Enzyme-Linked Immunosorbent Assay / veterinary; Fluorescent Antibody Technique, Indirect / veterinary; Lens, Crystalline / metabolism; Microscopy, Fluorescence / veterinary
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Distribution of ferritin chains in canine lenses with and without age-related nuclear cataracts

Molecular Vision, 15(256-59), 2404–2410.

By: M. Goralska, S. Nagar, L. Fleisher & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Iron metabolism in the eye: A review

Experimental Eye Research, 88(2), 204–215.

By: M. Goralska n, J. Ferrell n, J. Harned n, M. Lall n, S. Nagar n, L. Fleisher n, M. McGahan n

author keywords: iron; ferritin; transferrin; lens; retinal pigmented epithelium; retina
MeSH headings : Animals; Eye / metabolism; Eye Diseases / metabolism; Homeostasis; Humans; Iron / metabolism; Oxidative Stress; Signal Transduction / physiology
Sources: Web Of Science, Crossref
Added: August 6, 2018

2008 journal article

Iron regulates L-cystine uptake and glutathione levels in lens epithelial and retinal pigment epithelial cells by its effect on cytosolic aconitase

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 49(1), 310–319.

By: M. Lall n, J. Ferrell n, S. Nagar n, L. Fleisher n & M. McGahan n

MeSH headings : 2,2'-Dipyridyl / pharmacology; Aconitate Hydratase / antagonists & inhibitors; Aconitate Hydratase / metabolism; Amino Acid Transport System y+ / genetics; Amino Acid Transport System y+ / metabolism; Animals; Cells, Cultured; Chelating Agents / pharmacology; Cystine / metabolism; Cytosol; Dogs; Enzyme Inhibitors / pharmacology; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Fluorescent Antibody Technique, Indirect; Gene Expression; Glutathione / metabolism; Immunoblotting; Lens, Crystalline / drug effects; Lens, Crystalline / metabolism; Oxalates / pharmacology; Pigment Epithelium of Eye / metabolism; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Transferrin / pharmacology
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Ferritin H- and L-chains in fiber cell canine and human lenses of different ages

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 48(9), 3968–3975.

By: M. Goralska n, L. Fleisher n & M. McGahan n

MeSH headings : Adolescent; Adult; Aged; Aging / physiology; Animals; Apoferritins / metabolism; Blotting, Western; Dogs; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Ferritins / metabolism; Humans; Iron Radioisotopes / metabolism; Lens, Crystalline / cytology; Lens, Crystalline / metabolism; Middle Aged
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Lens epithelial cells synthesize and secrete ceruloplasmin: Effects of ceruloplasmin and transferrin on iron efflux and intracellular iron dynamics

EXPERIMENTAL EYE RESEARCH, 83(4), 721–727.

By: J. Harned n, L. Fleisher n & M. McGahan n

author keywords: lens; ceruloplasmin; iron; ferritin; transferrin; labile iron pool
MeSH headings : Animals; Ceruloplasmin / biosynthesis; Ceruloplasmin / pharmacology; Ceruloplasmin / physiology; Culture Media, Conditioned; Cytosol / metabolism; Dogs; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Ferritins / metabolism; Iron / metabolism; Lens Capsule, Crystalline / cytology; Lens Capsule, Crystalline / drug effects; Lens Capsule, Crystalline / metabolism; Tissue Culture Techniques; Transferrin / biosynthesis; Transferrin / pharmacology; Transferrin / physiology
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Differential degradation of ferritin H- and L-chains: Accumulation of L-chain-rich ferritin in lens epithelial cells

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 46(10), 3521–3529.

By: M. Goralska n, S. Nagar n, L. Fleisher n & M. McGahan n

MeSH headings : Aging / physiology; Animals; Apoferritins; Cells, Cultured; Cysteine Proteinase Inhibitors / pharmacology; Dogs; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Ferritins / metabolism; Iron / metabolism; Lens, Crystalline / drug effects; Lens, Crystalline / metabolism; Lysosomes / metabolism; Methionine / metabolism; Plasmids; Transfection
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Iron alters glutamate secretion by regulating cytosolic aconitase activity

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 288(5), C1117–C1124.

By: M. McGahan, J. Harned*, M. Mukunnemkeril, M. Goralska*, L. Fleisher* & J. Ferrell*

author keywords: retinal pigment epithelial cells; lens epithelial cells
MeSH headings : Aconitate Hydratase / antagonists & inhibitors; Aconitate Hydratase / metabolism; Animals; Cells, Cultured; Citric Acid / metabolism; Cytosol / metabolism; Dogs; Enzyme Activation / drug effects; Glutamates / metabolism; Iron / metabolism; Isocitrates / metabolism; Membrane Transport Proteins / metabolism; Oxalates / pharmacology; Pigment Epithelium of Eye / drug effects; Pigment Epithelium of Eye / enzymology; Riluzole / pharmacology; Vesicular Glutamate Transport Protein 1
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Rabbit pigmented ciliary epithelium produces interleukin-6 in response to inflammatory cytokines

EXPERIMENTAL EYE RESEARCH, 70(3), 271–279.

By: L. Fleisher n, M. McGahan n & J. Ferrell n

author keywords: interleukin-6; pigmented ciliary epithelium; interleukin-1; tumor necrosis factor-alpha; adenosine 3 ',5 '-cyclic monophosphate
MeSH headings : Animals; Cell Culture Techniques; Ciliary Body / immunology; Ciliary Body / metabolism; Cyclic AMP / metabolism; Cytokines / immunology; Endotoxins / immunology; Interleukin-1 / immunology; Interleukin-6 / biosynthesis; Pigment Epithelium of Eye / immunology; Pigment Epithelium of Eye / metabolism; Rabbits; Tumor Necrosis Factor-alpha / immunology
Source: Web Of Science
Added: August 6, 2018

1998 journal article

The effect of ascorbic acid and ferric ammonium citrate on iron uptake and storage in lens epithelial cells

EXPERIMENTAL EYE RESEARCH, 66(6), 687–697.

By: M. Goralska n, J. Harned n, L. Fleisher n & M. McGahan n

author keywords: ascorbic acid; ferritin; lens; iron; ferric ammonium citrate; transferrin
MeSH headings : Animals; Apoferritins / biosynthesis; Ascorbic Acid / pharmacology; Cells, Cultured; Chlorides; Dogs; Epithelial Cells / metabolism; Ferric Compounds / metabolism; Ferric Compounds / pharmacology; Homeostasis; Humans; Infant, Newborn; Iron Radioisotopes / metabolism; Lens, Crystalline / metabolism; Quaternary Ammonium Compounds / pharmacology; Transferrin / metabolism
Source: Web Of Science
Added: August 6, 2018

1998 journal article

The lens influences aqueous humor levels of transforming growth factor-beta 2

GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 236(4), 305–311.

By: J. Allen*, M. Davidson n, M. Nasisse*, L. Fleisher* & M. McGahan

MeSH headings : Animals; Aphakia / etiology; Aphakia / metabolism; Aphakia / pathology; Aqueous Humor / metabolism; Biological Assay; Cataract / etiology; Cataract / metabolism; Cataract / pathology; Cells, Cultured; Ciliary Body / cytology; Ciliary Body / metabolism; Disease Models, Animal; Dogs; Enzyme-Linked Immunosorbent Assay; Female; Lens, Crystalline / cytology; Lens, Crystalline / metabolism; Male; Pigment Epithelium of Eye / cytology; Pigment Epithelium of Eye / metabolism; Rabbits; Transforming Growth Factor beta / metabolism
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Mechanisms by which ascorbic acid increases ferritin levels in cultured lens epithelial cells

EXPERIMENTAL EYE RESEARCH, 64(3), 413–421.

By: M. Goralska n, J. Harned n, A. Grimes n, L. Fleisher n & M. McGahan n

author keywords: ascorbic acid; ferritin; lens; cataract
MeSH headings : Animals; Ascorbic Acid / metabolism; Ascorbic Acid / pharmacology; Base Sequence; Blotting, Northern; Cells, Cultured; DNA / metabolism; Deferoxamine / pharmacology; Dithiothreitol / pharmacology; Dogs; Epithelium / drug effects; Epithelium / metabolism; Ferric Compounds / metabolism; Ferritins / biosynthesis; Ferritins / drug effects; Ferritins / genetics; Hydrogen Peroxide / pharmacology; Lens, Crystalline / drug effects; Lens, Crystalline / metabolism; Molecular Sequence Data; Oxidation-Reduction; Protein Biosynthesis; Protein Synthesis Inhibitors / pharmacology; RNA, Messenger / drug effects; RNA, Messenger / metabolism
Source: Web Of Science
Added: August 6, 2018

1997 chapter

Nitric oxide in ocular inflammation

In Advances in ocular toxicology (pp. 121–131).

By: J. Allen n, M. McGahan n, L. Fleisher n, G. Jaffe* & C. Privalle*

Source: NC State University Libraries
Added: August 6, 2018

1996 journal article

Hemoglobin exacerbates the ocular inflammatory response to endotoxin

GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 234(10), 643–647.

By: M. McGahan n, A. Grimes n & L. Fleisher n

Source: Web Of Science
Added: August 6, 2018

1996 journal article

Interleukin-1 beta increases prostaglandin E(2)-stimulated adenosine 3',5'-cyclic monophosphate production in rabbit pigmented ciliary epithelium

EXPERIMENTAL EYE RESEARCH, 63(1), 91–104.

By: L. Fleisher n, M. McGahan n, J. Ferrell n & I. Pagan n

author keywords: ciliary epithelium; cyclic AMP, interleukin-1; prostaglandins; transforming growth factor-beta; pigmented ciliary epithelium
MeSH headings : Animals; Cells, Cultured; Colforsin / pharmacology; Cyclic AMP / biosynthesis; Cycloheximide / pharmacology; Cyclooxygenase Inhibitors / pharmacology; Dinoprostone / pharmacology; Dose-Response Relationship, Drug; Indomethacin / pharmacology; Interleukin-1 / pharmacology; Isoproterenol / pharmacology; Kinetics; Lipopolysaccharides / pharmacology; Pigment Epithelium of Eye / drug effects; Pigment Epithelium of Eye / metabolism; Protein Synthesis Inhibitors / pharmacology; Rabbits; Stimulation, Chemical; Transforming Growth Factor beta / pharmacology; Tumor Necrosis Factor-alpha / pharmacology; Up-Regulation; Vasoactive Intestinal Peptide / pharmacology
Source: Web Of Science
Added: August 6, 2018

1996 journal article

Intravitreal transforming growth factor-beta 2 decreases cellular infiltration in endotoxin-induced ocular inflammation in rabbits

CURRENT EYE RESEARCH, 15(1), 95–103.

By: J. Allen n, M. McGahan n, Y. Ogawa, D. Sellon n, B. Clark* & L. Fleisher n

author keywords: inflammation; in situ hybridization; rabbits; transforming growth factor-beta (TGF-beta); uveitis; endotoxin
MeSH headings : Animals; Anterior Eye Segment / pathology; Body Fluids / metabolism; Cell Movement / drug effects; Injections; Interleukin-1 / metabolism; Lipopolysaccharides; Male; Rabbits; Transforming Growth Factor beta / pharmacology; Uveitis / chemically induced; Uveitis / metabolism; Uveitis / pathology; Vitreous Body
Source: Web Of Science
Added: August 6, 2018

1996 journal article

Nitric oxide synthase inhibitors exert differential time-dependent effects on LPS-induced uveitis

EXPERIMENTAL EYE RESEARCH, 62(1), 21–28.

By: J. Allen n, M. McGahan n, J. Ferrell n, K. Adler n & L. Fleisher n

author keywords: nitric oxide; uveitis; nitric oxide synthase; nitric oxide synthase inhibitors; inflammation
MeSH headings : Animals; Aqueous Humor / metabolism; Arginine / analogs & derivatives; Arginine / therapeutic use; Cell Count / drug effects; Dose-Response Relationship, Drug; Eye Proteins / drug effects; Guanidines / therapeutic use; Kinetics; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide / antagonists & inhibitors; Nitric Oxide / physiology; Nitric Oxide Synthase / antagonists & inhibitors; Rabbits; Uveitis, Anterior / etiology; Uveitis, Anterior / metabolism; Uveitis, Anterior / prevention & control
Source: Web Of Science
Added: August 6, 2018

1995 journal article

INFLAMMATION-INDUCED CHANGES IN ADENOSINE 3',5'-CYCLIC-MONOPHOSPHATE PRODUCTION BY CILIARY EPITHELIAL-CELL BILAYERS

EXPERIMENTAL EYE RESEARCH, 60(2), 165–171.

By: L. Fleisher n, J. Ferrell n & M. Mcgahan n

author keywords: ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE; INTERLEUKIN-1; TUMOR NECROSIS FACTOR; ANTERIOR UVEA; CILIARY EPITHELIUM; ENDOTOXIN; UVEITIS
MeSH headings : Animals; Ciliary Body / drug effects; Ciliary Body / metabolism; Colforsin / pharmacology; Culture Techniques; Cyclic AMP / biosynthesis; Epithelium / drug effects; Epithelium / metabolism; Interleukin-1 / pharmacology; Isoproterenol / pharmacology; Lipopolysaccharides / pharmacology; Male; Rabbits; Recombinant Proteins / pharmacology; Tumor Necrosis Factor-alpha / pharmacology; Uveitis, Anterior / etiology; Uveitis, Anterior / metabolism
Source: Web Of Science
Added: August 6, 2018

1995 journal article

IRON UPTAKE BY CULTURED LENS EPITHELIAL-CELLS

GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 233(6), 354–359.

By: M. Mcgahan n, A. Grimes n, M. Nasisse n & L. Fleisher n

MeSH headings : 2,2'-Dipyridyl / pharmacology; Animals; Ascorbic Acid / pharmacology; Biological Transport / drug effects; Cataract / metabolism; Cataract / pathology; Cells, Cultured; Dogs; Epithelium / metabolism; Iron / metabolism; Iron Radioisotopes; Lens, Crystalline / cytology; Lens, Crystalline / metabolism; Receptors, Transferrin / metabolism; Transferrin / metabolism
Source: Web Of Science
Added: August 6, 2018

1995 journal article

MEDIATORS OF THE OCULAR INFLAMMATORY RESPONSE TO INTERLEUKIN-1-BETA PLUS TUMOR-NECROSIS-FACTOR-ALPHA

GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 233(2), 94–100.

By: L. Fleisher n, J. Ferrell n & C. Mcgahan n

MeSH headings : Animals; Indomethacin / therapeutic use; Interleukin-1 / toxicity; Male; Platelet Activating Factor / antagonists & inhibitors; Platelet Activating Factor / metabolism; Rabbits; Tumor Necrosis Factor-alpha / toxicity; Uveitis, Anterior / immunology; Uveitis, Anterior / prevention & control; Uveitis, Posterior / immunology; Uveitis, Posterior / prevention & control
Source: Web Of Science
Added: August 6, 2018

1995 journal article

TRANSFERRIN SECRETION BY LENS EPITHELIAL-CELLS IN CULTURE

EXPERIMENTAL EYE RESEARCH, 60(6), 667–673.

By: M. Mcgahan n, J. Harned n, M. Goralska n, B. Sherry n & L. Fleisher n

author keywords: TRANSFERRIN; LENS; ANTIOXIDANTS; GROWTH FACTORS; AQUEOUS HUMOR
MeSH headings : Animals; Aqueous Humor / chemistry; Blotting, Northern; Cells, Cultured; Ciliary Body / metabolism; Dogs; Epithelium / metabolism; Lens, Crystalline / metabolism; Rabbits; Secretory Rate; Time Factors; Transferrin / metabolism; Vitreous Body / chemistry
Source: Web Of Science
Added: August 6, 2018

1994 journal article

INFLUENCE OF EXPOSURE TIME ON INFLAMMATORY RESPONSE TO NEODYMIUM - YAG CYCLOPHOTOCOAGULATION IN RABBITS

ARCHIVES OF OPHTHALMOLOGY, 112(7), 977–981.

By: D. Echelman*, M. Nasisse*, M. Shields, M. Mcgahan & L. Fleisher*

MeSH headings : Animals; Aqueous Humor / metabolism; Ciliary Body / metabolism; Ciliary Body / pathology; Ciliary Body / surgery; Erythrocyte Count; Inflammation; Laser Coagulation / adverse effects; Leukocyte Count; Rabbits; Time Factors; Uveitis / etiology; Uveitis / metabolism; Uveitis / pathology
Source: Web Of Science
Added: August 6, 2018

1994 journal article

REGULATION OF FERRITIN LEVELS IN CULTURED LENS EPITHELIAL-CELLS

EXPERIMENTAL EYE RESEARCH, 59(5), 551–555.

By: M. Mcgahan n, J. Harned n, A. Grimes n & L. Fleisher n

author keywords: IRON; FERRITIN; LENS EPITHELIAL CELLS; PEROXIDE; FREE RADICALS; ASCORBIC ACID
MeSH headings : Animals; Cells, Cultured; Chelating Agents / pharmacology; Deferoxamine / pharmacology; Dogs; Enzyme-Linked Immunosorbent Assay; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Ferritins / metabolism; Hemin / pharmacology; Lens, Crystalline / cytology; Lens, Crystalline / drug effects; Lens, Crystalline / metabolism
Source: Web Of Science
Added: August 6, 2018

1994 personal communication

TRANSFERRIN INHIBITS THE OCULAR INFLAMMATORY RESPONSE

MCGAHAN, M. C., GRIMES, A. M., & FLEISHER, L. N. (1994, April).

By: M. Mcgahan, A. Grimes* & L. Fleisher*

MeSH headings : Animals; Eye Proteins / metabolism; Leukocyte Count / drug effects; Rats; Transferrin / therapeutic use; Uveitis / prevention & control; Xanthine Oxidase
Source: Web Of Science
Added: August 6, 2018

1992 journal article

CELLULAR-RESPONSE TO INTRAVITREAL INJECTION OF ENDOTOXIN AND XANTHINE-OXIDASE IN RABBITS

GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 230(5), 463–467.

By: M. Mcgahan n & L. Fleisher n

MeSH headings : Animals; Aqueous Humor / cytology; Endotoxins / administration & dosage; Endotoxins / pharmacology; Escherichia coli; Injections; Leukocyte Count / drug effects; Leukocytes; Lipopolysaccharides; Rabbits; Vitreous Body / cytology; Xanthine Oxidase / administration & dosage; Xanthine Oxidase / pharmacology
Source: Web Of Science
Added: August 6, 2018

1992 journal article

Effects of copper loading and depletion on rabbit superoxide dismutase activity

Trace Elements in Medicine, 9, 55–58.

By: J. Ferrell, L. Fleisher, M. Smith & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1992 journal article

Synergistic uveitic effects of tumor necrosis factor-alpha and interleukin-1 beta

Investigative Ophthalmology and Visual Science, 33, 2120–2127.

By: L. Fleisher, J. Ferrell & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1991 journal article

EFFECTS OF COPPER DEPLETION AND D-PENICILLAMINE TREATMENT ON THE OCULAR INFLAMMATORY RESPONSE

AGENTS AND ACTIONS, 34(3-4), 405–409.

By: M. Mcgahan n, L. Fleisher n & A. Grimes n

MeSH headings : Animals; Antioxidants; Aqueous Humor / metabolism; Ceruloplasmin / metabolism; Copper / deficiency; Copper / metabolism; Endophthalmitis / metabolism; Endophthalmitis / pathology; Free Radicals; Penicillamine / pharmacology; Rabbits
Source: Web Of Science
Added: August 6, 2018

1991 journal article

Lipid mediators of TNF- induced uveitis

Investigative Ophthalmology and Visual Science, 32, 2393–2399.

By: L. Fleisher, J. Ferrell & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

1990 journal article

OCULAR INFLAMMATORY EFFECTS OF INTRAVITREALLY INJECTED TUMOR NECROSIS FACTOR-ALPHA AND ENDOTOXIN

INFLAMMATION, 14(3), 325–335.

By: L. Fleisher n, J. Ferrell n & M. Mcgahan n

Source: Web Of Science
Added: August 6, 2018

1989 journal article

CLINICAL SIGNS OF ACUTE OCULAR INFLAMMATORY RESPONSE TO ENDOTOXIN ARE NOT ALTERED BY INCREASING ANTIOXIDANT POTENCY OF INTRAOCULAR FLUIDS

INFLAMMATION, 13(4), 393–400.

By: M. Mcgahan n, L. Fleisher n & A. Grimes n

MeSH headings : Animals; Antioxidants; Aqueous Humor / metabolism; Ceruloplasmin / metabolism; Copper / blood; Copper / pharmacology; Endotoxins / toxicity; Rabbits; Transferrin / metabolism; Uveitis / physiopathology
Source: Web Of Science
Added: August 6, 2018

1989 journal article

DIMETHYLTHIOUREA INHIBITS THE INFLAMMATORY RESPONSE TO INTRAVITREALLY-INJECTED ENDOTOXIN

EXPERIMENTAL EYE RESEARCH, 48(4), 561–567.

By: L. Fleisher n, J. Ferrell n, N. Olson n & M. Mcgahan n

MeSH headings : Animals; Endotoxins; Escherichia coli; Male; Rabbits; Thiourea / administration & dosage; Thiourea / analogs & derivatives; Thiourea / pharmacology; Uveitis, Anterior / chemically induced; Uveitis, Anterior / prevention & control; Vitreous Body
Source: Web Of Science
Added: August 6, 2018

1989 journal article

Ferroxidase activity increases dramatically in the aqueous humor during the ocular inflammatory response

Ophthalmic Research, 21, 221–225.

By: M. McGahan n, A. Grimes* & L. Fleisher*

MeSH headings : Animals; Aqueous Humor / enzymology; Ceruloplasmin / analysis; Ceruloplasmin / metabolism; Copper / analysis; Copper / blood; Endophthalmitis / enzymology; Endotoxins; Escherichia coli / metabolism; Proteins / analysis; Rabbits; Spectrophotometry, Atomic; Time Factors; Vitreous Body
Source: NC State University Libraries
Added: August 6, 2018

1988 journal article

Inflammation-induced changes in the concentration of iron and total-iron-binding capacity in the intraocular fluids of rabbits

Graefes Archive for Clinical and Experimental Ophthalmology, 226, 27–30.

By: M. McGahan n & L. Fleisher n

MeSH headings : Animals; Aqueous Humor / metabolism; Endophthalmitis / chemically induced; Endophthalmitis / metabolism; Eye / metabolism; Iron / analysis; Iron / blood; Iron / metabolism; Rabbits; Transferrin / metabolism; Vitreous Body / metabolism
Source: NC State University Libraries
Added: August 6, 2018

1986 journal article

A MICROMETHOD FOR THE DETERMINATION OF IRON AND TOTAL IRON-BINDING-CAPACITY IN INTRAOCULAR FLUIDS AND PLASMA USING ELECTROTHERMAL ATOMIC-ABSORPTION SPECTROSCOPY

ANALYTICAL BIOCHEMISTRY, 156(2), 397–402.

By: M. Mcgahan n & L. Fleisher n

MeSH headings : Animals; Aqueous Humor / metabolism; Cats; Dogs; Electrochemistry; Eye / metabolism; Horses; Indicators and Reagents; Iron / analysis; Iron / blood; Iron / metabolism; Rabbits; Species Specificity; Spectrophotometry, Atomic; Swine; Temperature; Vitreous Body / metabolism
Source: Web Of Science
Added: August 6, 2018

1986 journal article

ANTIOXIDANT ACTIVITY OF AQUEOUS AND VITREOUS-HUMOR FROM THE INFLAMED RABBIT EYE

CURRENT EYE RESEARCH, 5(9), 641–645.

By: M. Mcgahan & L. Fleisher*

MeSH headings : Animals; Antioxidants / metabolism; Aqueous Humor / metabolism; Brain / metabolism; Endophthalmitis / metabolism; Eye Proteins / metabolism; Male; Malondialdehyde / biosynthesis; Oxidation-Reduction; Rabbits; Time Factors; Vitreous Body / metabolism
Source: Web Of Science
Added: August 6, 2018

1986 journal article

TIME COURSE FOR PROSTAGLANDIN SYNTHESIS BY RABBIT LENS DURING ENDOTOXIN-INDUCED OCULAR INFLAMMATION

CURRENT EYE RESEARCH, 5(9), 629–634.

By: L. Fleisher n & M. Mcgahan n

MeSH headings : Animals; Body Fluids / metabolism; Dinoprost; Dinoprostone; Endophthalmitis / chemically induced; Endophthalmitis / metabolism; Endophthalmitis / pathology; Endotoxins / pharmacology; Escherichia coli; Lens, Crystalline / metabolism; Male; Prostaglandins E / biosynthesis; Prostaglandins F / biosynthesis; Rabbits
Source: Web Of Science
Added: August 6, 2018

1985 journal article

ENDOTOXIN-INDUCED OCULAR INFLAMMATION INCREASES PROSTAGLANDIN-E2 SYNTHESIS BY RABBIT LENS

EXPERIMENTAL EYE RESEARCH, 40(5), 711–719.

By: L. Fleisher n & M. Mcgahan n

MeSH headings : Animals; Aqueous Humor / metabolism; Dinoprostone; Endotoxins / pharmacology; Escherichia coli; Eye / drug effects; Eye / pathology; Inflammation / metabolism; Lens, Crystalline / metabolism; Male; Prostaglandins E / biosynthesis; Rabbits
Source: Web Of Science
Added: August 6, 2018