Center for Human Health and the Environment

Works Published in 1992

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Displaying works 21 - 27 of 27 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

1992 journal article

PLATELET-ACTIVATING-FACTOR PROVOKES RELEASE OF MUCIN-LIKE GLYCOPROTEINS FROM GUINEA-PIG RESPIRATORY EPITHELIAL-CELLS VIA A LIPOXYGENASE-DEPENDENT MECHANISM

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 6(5), 550–556.

By: K. Adler n, N. Akley n & W. Glasgow n

MeSH headings : Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors / pharmacology; Epithelium / metabolism; Glyceryl Ethers / pharmacology; Guinea Pigs; Hydroxyeicosatetraenoic Acids / metabolism; In Vitro Techniques; Indomethacin / pharmacology; Lipoxygenase / physiology; Lipoxygenase Inhibitors / pharmacology; Masoprocol / pharmacology; Mucins / metabolism; Phospholipid Ethers / pharmacology; Platelet Activating Factor / pharmacology; Platelet Membrane Glycoproteins; Receptors, Cell Surface / antagonists & inhibitors; Receptors, G-Protein-Coupled; Thiazoles / pharmacology; Trachea / metabolism
TL;DR: The results suggest that PAF stimulates release of MLG by guinea pig tracheal epithelial cells in vitro by a mechanism involving binding of PAF to receptors on epithelial cell surfaces, stimulation of lipoxygenase metabolism of arachidonic acid to HETEs within the epithelium, and stimulation of secretion by these epithelial-derived HetEs via an autocrine or paracrine mechanism. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1992 review

INTERACTIONS BETWEEN AIRWAY EPITHELIUM AND MEDIATORS OF INFLAMMATION

[Review of ]. EXPERIMENTAL LUNG RESEARCH, 18(3), 299–322.

By: L. Cohn n & K. Adler n

MeSH headings : Bronchi / metabolism; Epithelial Cells; Epithelium / metabolism; Humans; Inflammation / metabolism; Trachea / metabolism
TL;DR: Recent studies have indicated that airway epithelial cells also can act as "effector" cells, responding to a variety of exogenous and/or endogenous stimuli by generating and releasing additional mediators of inflammation, such as eicosanoids, reactive oxygen species, and cytokines. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1992 journal article

INFLAMMATORY MEDIATORS AND THE GENERATION AND RELEASE OF REACTIVE OXYGEN SPECIES BY AIRWAY EPITHELIUM INVITRO

CHEST, 101(3), S53–S54.

By: K. Adler n, V. Kinnula, N. Akley n, J. Lee n, L. Cohn n & J. Crapo n

MeSH headings : Animals; Cells, Cultured; Endothelins / pharmacology; Epithelium / metabolism; Guinea Pigs; Hydrogen Peroxide / metabolism; Platelet Activating Factor / pharmacology; Trachea / metabolism
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1992 article

Ozone increases platelet activating factor and activates phospholipases (PLA2 and PLC) in primary guinea pig tracheal epithelial cells (GPTE).

American Review of Respiratory Disease, Vol. 145, p. A99.

By: M. Friedman, D. Wright, L. Dailey, N. Akley, R. Devlin & K. Adler

Source: NC State University Libraries
Added: August 6, 2018

1992 article

Guinea pig tracheal epithelial cells in primary air/liquid interface culture scavenge H2O2 via a mechanism only partially dependent on catalase and the glutathione system.

FASEB Journal, Vol. 6, p. A939.

Source: NC State University Libraries
Added: August 6, 2018

1992 article

Airway epithelial cells release factor(s) that stimulate proliferation of airway smooth muscle cells in vitro.

Molecular Biology of the Cell, Vol. 3, p. 175a.

By: P. Rippetoe, M. Absher, W. Makrides, K. Adler & J. Evans

Source: NC State University Libraries
Added: August 6, 2018

1992 journal article

Attempted Mechanical Transfer of Ehrlichia risticii by Tabanids (Diptera: Tabanidae)

Journal of Medical Entomology, 29(5), 806–812.

By: J. Levine n, M. Levy n, W. Nicholson n, W. Irby n, R. Gager n & C. Apperson n

author keywords: INSECTA; TABANIDAE; EHRLICHIA-RISTICII; MECHANICAL TRANSFER
MeSH headings : Animals; Diptera; Ehrlichiosis / transmission; Insect Vectors
TL;DR: These studies document that E. risticii-infected cells can be retained on mouthparts and potentially transferred by tabanids. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

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