Works Published in 2016
Displaying works 41 - 60 of 284 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2016 journal article
Inhibiting Hexamer Disassembly of Human UDP-Glucose Dehydrogenase by Photoactivated Amino Acid Cross-Linking
Biochemistry, 55(22), 3157–3164.
MeSH headings : Amino Acids / chemistry; Amino Acids / radiation effects; Catalysis; Cross-Linking Reagents; Humans; Kinetics; Light; Models, Molecular; Oxidation-Reduction; Photochemical Processes; Protein Conformation; Protein Multimerization / radiation effects; Uridine Diphosphate Glucose / metabolism; Uridine Diphosphate Glucose Dehydrogenase / chemistry; Uridine Diphosphate Glucose Dehydrogenase / metabolism
TL;DR:
A model for catalysis in which the ability to dissociate the dimer-dimer interface is as important for maximal enzyme function as has been previously shown for the formation of the hexamer is supported.
(via Semantic Scholar)
digitalcommons.unl.edu (repository)
Source: Crossref
Added: February 24, 2020
2016 journal article
Loss of exogenous androgen dependence by prostate tumor cells is associated with elevated glucuronidation potential
Hormones and Cancer, 7(4), 260–271.
author keywords: Prostate cancer; Castration resistance; Dihydrotestosterone; Detoxification; LNCaP
MeSH headings : Androgens / pharmacology; Cell Line, Tumor; Gene Expression Regulation, Neoplastic / drug effects; Glucuronides / metabolism; Glucuronosyltransferase / metabolism; Humans; Kallikreins / genetics; Kallikreins / metabolism; Male; Minor Histocompatibility Antigens / metabolism; Models, Biological; Promoter Regions, Genetic; Prostate-Specific Antigen / genetics; Prostate-Specific Antigen / metabolism; Prostatic Neoplasms / genetics; Prostatic Neoplasms / metabolism; Prostatic Neoplasms, Castration-Resistant / genetics; Prostatic Neoplasms, Castration-Resistant / metabolism; Receptors, Androgen / metabolism; Uridine Diphosphate Glucose Dehydrogenase / metabolism
TL;DR:
A model in which the aberrant partitioning of UDP-glucuronate and other UDP-sugars into alternative pathways during androgen deprivation contributes to the loss of prostate tumor cell androgen sensitivity by promoting altered cell surface proteoglycan expression is supported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: February 24, 2020
2016 journal article
DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
The American Journal of Human Genetics, 98(4), 680–696.
MeSH headings : Asthma / etiology; Asthma / genetics; Child; Child, Preschool; Chromosome Mapping; Cleft Lip / etiology; Cleft Lip / genetics; Cleft Palate / etiology; Cleft Palate / genetics; DNA Methylation; Epigenesis, Genetic; Female; Genetic Association Studies; Humans; Infant; Infant, Newborn; Pregnancy; Smoking / adverse effects; White People / genetics
TL;DR:
This large scale meta-analysis of methylation data identified numerous loci involved in response to maternal smoking in pregnancy with persistence into later childhood and provide insights into mechanisms underlying effects of this important exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Crossref
Added: February 24, 2020
2016 journal article
Integrative approaches for large-scale transcriptome-wide association studies
Nature Genetics, 48(3), 245–252.
MeSH headings : Animals; Gene Expression Regulation / genetics; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Humans; Mice; Obesity / genetics; Obesity / pathology; Phenotype; Quantitative Trait Loci / genetics; Transcriptome / genetics
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: February 24, 2020
2016 journal article
Comment
Journal of the American Statistical Association, 111(515), 936–942.
TL;DR:
It is argued that NPB methods can have tremendous value as an engine for policy-search algorithms used to estimate an optimal treatment regime within a prespecified class, and may possess a number of advantages over existing methods in the context of policy- search algorithms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020
2016 journal article
A cell wall-bound anionic peroxidase, PtrPO21, is involved in lignin polymerization in Populus trichocarpa
Tree Genetics & Genomes, 12(2).
author keywords: Lignin polymerization; Populus trichocarpa; Lignin peroxidase; LC-MS/MS; Lignin systems biology
TL;DR:
Differentially expressed gene (DEG) analysis of PtrPO21 downregulated transgenics identified a significant overexpression of PtPrx35, suggesting a compensatory effect within the peroxidase family.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 24, 2020
2016 journal article
Recovery of stepping and coordination in dogs following acute thoracolumbar intervertebral disc herniations
The Veterinary Journal, 213, 59–63.
author keywords: Canine; Gait; Locomotion; Paralysis; Spinal cord injury
MeSH headings : Acute Disease; Animals; Dog Diseases / etiology; Dog Diseases / surgery; Dogs; Female; Forelimb / physiology; Hindlimb / physiology; Intervertebral Disc / pathology; Intervertebral Disc / surgery; Intervertebral Disc Displacement / etiology; Intervertebral Disc Displacement / surgery; Intervertebral Disc Displacement / veterinary; Male; Prospective Studies; Spinal Cord Injuries / etiology; Spinal Cord Injuries / surgery; Spinal Cord Injuries / veterinary; Walking
TL;DR:
Recovery of coordination was incomplete in dogs that showed good recovery of stepping in the 6 weeks following surgical decompression of dogs with TL-IVDH.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Crossref
Added: February 24, 2020
2016 journal article
Use of plankton-derived vitamin B1 precursors, especially thiazole-related precursor, by key marine picoeukaryotic phytoplankton
The ISME Journal, 11(3), 753–765.
MeSH headings : Chlorophyta / genetics; Eukaryota / metabolism; Plankton / classification; Plankton / metabolism; Pyrimidines; Thiamine / chemistry; Thiamine / metabolism; Thiazoles / metabolism
TL;DR:
Thiazole-related B1 precursors are found to be important micronutrients promoting the survival of abundant phytoplankton influencing surface ocean production and biogeochemical cycling.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 12, 2020
2016 journal article
Marine Non-Cyanobacterial Diazotrophs: Moving beyond Molecular Detection
Trends in Microbiology, 24(11), 916–927.
MeSH headings : Archaea / enzymology; Archaea / genetics; Archaea / metabolism; Bacteria / enzymology; Bacteria / genetics; Bacteria / metabolism; Cyanobacteria / enzymology; Cyanobacteria / metabolism; Ecology; Heterotrophic Processes; Nitrogen / metabolism; Nitrogen Cycle; Nitrogen Fixation / physiology; Nitrogenase / genetics; Oceans and Seas; Oxidoreductases / classification; Phylogeny; Seawater / microbiology
TL;DR:
The need for combining rate measurements and molecular analyses of field samples with cultivation studies in order to clarify the ecology of non-cyanobacteria and their contribution to marine N2 fixation on local and global scales is highlighted.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 5, 2020
2016 journal article
The mitogenome of the bed bug Cimex lectularius (Hemiptera: Cimicidae)
Mitochondrial DNA Part B, 1(1), 425–427.
author keywords: Arthropods; blood feeding; Hemiptera; pest; true bugs
TL;DR:
Phylogenetic analysis of all protein-coding genes indicates that C. lectularius is clearly a member of a paraphyletic Cimicomorpha clade within the Order Hemiptera, and has a similar AT nucleotide composition bias found in other insects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Crossref
Added: February 5, 2020
2016 journal article
Unique features of a global human ectoparasite identified through sequencing of the bed bug genome
Nature Communications, 7(1).
MeSH headings : Animals; Bedbugs / genetics; Ectoparasitic Infestations; Feeding Behavior; Gene Transfer, Horizontal / genetics; Genome; Host-Parasite Interactions / genetics; Humans; Insecticide Resistance / genetics; Insecticides; Sequence Analysis, DNA
TL;DR:
The authors sequence the genome of the bed bug and identify reductions in chemosensory genes, expansion of genes associated with blood digestion and genes linked to pesticide resistance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
17. Partnerships for the Goals
(OpenAlex)
Source: Crossref
Added: February 5, 2020
2016 journal article
Comparison of ingestion and topical application of insecticides against the common bed bug, Cimex lectularius (Hemiptera: Cimicidae)
Pest Management Science, 73(3), 521–527.
author keywords: bed bug; Cimex lectularius; mortality; systemic control; liquid bait
MeSH headings : Animals; Bedbugs / growth & development; Ectoparasitic Infestations / prevention & control; Guanidines; Insect Control / methods; Insecticides; Ivermectin / analogs & derivatives; Male; Neonicotinoids; Nymph; Oxazines; Pyrazoles; Thiazoles
TL;DR:
Fipronil, clothianidin and abamectin have potential for being incorporated into a liquid bait for bed bug control; indoxacarb and DCJW were not effective.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: January 28, 2020
2016 journal article
Effects of foraging distance on macronutrient balancing and performance in the German cockroach Blattella germanica
The Journal of Experimental Biology, 220(2), 304–311.
author keywords: Carbohydrate; Foraging effort; Juvenile development; Nutrient regulation; Protein; Sexual maturation
MeSH headings : Animal Nutritional Physiological Phenomena; Animals; Blattellidae / growth & development; Blattellidae / physiology; Energy Metabolism; Feeding Behavior; Female; Lipid Metabolism; Male; Nymph / growth & development; Nymph / physiology; Oocytes / growth & development; Sexual Maturation
TL;DR:
A positive effect of foraging distance on fitness-related parameters at two life stages is shown, in both cases involving increased consumption of specific nutrients corresponding to requirements at the respective life stage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science; OpenAlex)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Crossref
Added: January 28, 2020
2016 journal article
Discrimination between lineage-specific shelters by bat- and human-associated bed bugs does not constitute a stable reproductive barrier
Parasitology Research, 116(1), 237–242.
author keywords: Pre-copulation reproduction isolation; Pheromones; Parasites; Aggregation behavior
MeSH headings : Animals; Bedbugs / classification; Bedbugs / genetics; Bedbugs / physiology; Biological Assay; Chiroptera / parasitology; Ectoparasitic Infestations / parasitology; Ectoparasitic Infestations / veterinary; Female; Humans; Hybridization, Genetic; Male; Odorants / analysis; Reproduction
TL;DR:
Bed bugs show no preferences for lineage-specific shelters, strongly suggesting that semiochemicals associated with shelters alone do not function in reproductive isolation, and instead suggest a pre-copulation isolation mechanism.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: January 28, 2020
2016 journal article
Obp56h Modulates Mating Behavior in Drosophila melanogaster
G3: Genes|Genomes|Genetics, 6(10), 3335–3342.
author keywords: odorant binding protein; olfaction; cuticular hydrocarbon; pheromone; 5-tricosene; FlyBook
MeSH headings : Animals; Animals, Genetically Modified; Copulation; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Drosophila melanogaster / physiology; Female; Gene Expression Profiling; Gene Expression Regulation; Gene Knockdown Techniques; Genome-Wide Association Study; Hydrocarbons / metabolism; Male; Metabolomics; Psychomotor Performance; RNA Interference; Receptors, Odorant / genetics; Receptors, Odorant / metabolism; Sexual Behavior, Animal
TL;DR:
It is reported that RNAi knockdown of Obp56h gene expression in Drosophila melanogaster enhances mating behavior by reducing courtship latency and modulation of mating behavior is accompanied by altered cuticular hydrocarbon profiles and implicate 5-T as a possible ligand for Obp 56h.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: January 28, 2020
2016 journal article
Laboratory and Field Evaluation of Zyrox Fly Granular Bait Against Asian and German Cockroaches (Dictyoptera: Blattellidae)
Journal of Economic Entomology, 109(4), 1807–1812.
author keywords: Blattella asahinai; Blattella germanica; Zyrox Fly Granular Bait; cyantraniliprole; Maxforce Complete Granular Insect Bait
MeSH headings : Animals; Blattellidae; Insect Control; Insecticides; North Carolina; Pyrazoles; Species Specificity; ortho-Aminobenzoates
TL;DR:
Zyrox Fly Bait appears to be effective against the Asian and German cockroaches, and could be another tool in an integrated pest management program, if its label could be extended or the active ingredient formulated into a cockroach bait.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: January 28, 2020
2016 journal article
Feel the heat: activation, orientation and feeding responses of bed bugs to targets at different temperatures
The Journal of Experimental Biology, 219(23), 3773–3780.
author keywords: Cimex lectularius; Cimicidae; Host attraction; Sensory cues; Thermal orientation; Thermotaxis
MeSH headings : Animals; Bedbugs / physiology; Feeding Behavior / physiology; Hot Temperature; Motor Activity / physiology; Orientation, Spatial; Taxis Response / physiology
TL;DR:
Bed bugs utilize heat to locate and feed on hosts, and show a characteristic increase in the number of responders and decrease in response time with increasing target temperature, and bed bug feeding is shown to be relative to ambient temperature, not an absolute response to feeder blood temperature.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: January 28, 2020
2016 journal article
A note on multiple imputation for method of moments estimation
Biometrika, 103(1), 244–251.
author keywords: Bayesian method; Congeniality; Missingness at random; Proper imputation; Survey sampling
Sources: Crossref, NC State University Libraries
Added: January 14, 2020
2016 journal article
Fractional Imputation in Survey Sampling: A Comparative Review
Statistical Science, 31(3), 415–432.
author keywords: Item nonresponse; missing at random; Monte Carlo EM; multiple imputation; synthetic imputation
TL;DR:
The empirical performance of FI is demonstrated with respect to multiple imputation using a pseudo finite population generated from a sample from the Monthly Retail Trade Survey conducted by the US Census Bureau.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 14, 2020
2016 journal article
A goodness-of-fit test for structural nested mean models
Biometrika, 103(3), 734–741.
author keywords: Causal inference; Estimating equation; HIV; AIDs; Over-identification restrictions test
TL;DR:
A goodness-of-fit test based on modified over-identification restrictions tests for evaluating a treatment effect model is derived, and it is shown that the test is doubly robust in the sense that it has the correct Type I error if either the treatment initiation model or a nuisance regression outcome model is correctly specified.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 14, 2020
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