Andrew K. Hotchkiss
Works (17)
Updated: August 20th, 2023 21:15
2010 review
Environmental-endocrine control of reproductive maturation in gastropods: implications for the mechanism of tributyltin-induced imposex in prosobranchs
[Review of ]. ECOTOXICOLOGY, 19(1), 4–23.
co-author countries:
United States of America 🇺🇸
author keywords: Mollusk; Endocrinology; Tributyltin; Imposex; Retinoid X-receptor
MeSH headings : Animal Nutritional Physiological Phenomena; Animals; Female; Male; Models, Biological; Photoperiod; Retinoid X Receptors / metabolism; Sex Characteristics; Sex Differentiation / drug effects; Signal Transduction / drug effects; Snails / drug effects; Snails / physiology; Temperature; Tretinoin / metabolism; Trialkyltin Compounds / metabolism; Trialkyltin Compounds / toxicity
Sources: Web Of Science, ORCID
Added: August 6, 2018
2010 journal article
In utero and lactational exposure to bisphenol A, in contrast to ethinyl estradiol, does not alter sexually dimorphic behavior, puberty, fertility, and anatomy of female LE rats
Toxicological Sciences, 114(1), 133–148.
Source: NC State University Libraries
Added: August 6, 2018
2009 journal article
Cumulative Effects of In Utero Administration of Mixtures of "Antiandrogens" on Male Rat Reproductive Development
TOXICOLOGIC PATHOLOGY, 37(1), 100–113.
co-author countries:
United States of America 🇺🇸
author keywords: reproductive system; male reproduction; endocrine disrupters
MeSH headings : Androgen Antagonists / toxicity; Animals; Bridged Bicyclo Compounds / toxicity; Complex Mixtures / toxicity; Dibutyl Phthalate / toxicity; Diethylhexyl Phthalate / toxicity; Drug Combinations; Drug Synergism; Female; Fungicides, Industrial / toxicity; Genital Diseases, Male / chemically induced; Genital Diseases, Male / embryology; Genitalia, Male / abnormalities; Genitalia, Male / drug effects; Hypospadias / chemically induced; Male; Maternal Exposure; Oxazoles / toxicity; Phthalic Acids / toxicity; Pregnancy; Rats; Receptors, Androgen / drug effects; Receptors, Androgen / metabolism; Sexual Maturation / drug effects
journals.sagepub.com (publisher PDF)
Source: Web Of Science
Added: August 6, 2018
2008 journal article
A mixture of five phthalate esters inhibits fetal testicular testosterone production in the sprague-dawley rat in a cumulative, dose-additive manner
TOXICOLOGICAL SCIENCES, 105(1), 153–165.
co-author countries:
United States of America 🇺🇸
author keywords: androgens; prenatal; reproductive tract; phthalates; cumulative risk; structure activity relationship
MeSH headings : Animals; Body Weight / drug effects; Dibutyl Phthalate / analogs & derivatives; Dibutyl Phthalate / toxicity; Diethylhexyl Phthalate / toxicity; Dose-Response Relationship, Drug; Female; Fetus / drug effects; Logistic Models; Male; Phthalic Acids / toxicity; Pregnancy; Rats; Rats, Sprague-Dawley; Testis / drug effects; Testis / metabolism; Testosterone / biosynthesis
Source: Web Of Science
Added: August 6, 2018
2008 article
Diverse mechanisms of anti-androgen action: impact on male rat reproductive tract development
Wilson, V. S., Blystone, C. R., Hotchkiss, A. K., Rider, C. V., & Gray, L. E., Jr. (2008, April). INTERNATIONAL JOURNAL OF ANDROLOGY, Vol. 31, pp. 178–185.
co-author countries:
United States of America 🇺🇸
author keywords: androgen receptor; anti-androgen; linuron; phthalate; prochloraz; reproductive development; vinclozolin
MeSH headings : Androgen Antagonists / pharmacology; Animals; Genitalia, Male / drug effects; Genitalia, Male / embryology; Male; Rats
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Environmental cues trigger seasonal regression of primary and accessory sex organs of the mud snail, Ilyanassa obsoleta
JOURNAL OF MOLLUSCAN STUDIES, 74, 301–303.
Sources: Web Of Science, ORCID
Added: August 6, 2018
2008 journal article
Of Mice and Men (and Mosquitofish): Antiandrogens and Androgens in the Environment
BIOSCIENCE, 58(11), 1037–1050.
co-author countries:
United States of America 🇺🇸
author keywords: androgens; vertebrates; reproductive development; environmental chemicals; antiandrogens
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Synchronized expression of retinoid X receptor mRNA with reproductive tract recrudescence in an imposex-susceptible mollusc
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 42(4), 1345–1351.
co-author countries:
United States of America 🇺🇸
MeSH headings : Amino Acid Sequence; Animals; Female; Male; Molecular Sequence Data; Mollusca / anatomy & histology; Phylogeny; RNA, Messenger / genetics; Reproduction; Retinoid X Receptors / chemistry; Retinoid X Receptors / genetics; Sequence Homology, Amino Acid; Species Specificity
Sources: Web Of Science, ORCID
Added: August 6, 2018
2008 journal article
The contribution of steroidal androgens and estrogens to reproductive maturation of the eastern mud snail Ilyanassa obsoleta
GENERAL AND COMPARATIVE ENDOCRINOLOGY, 156(1), 15–26.
author keywords: androgens; estrogens; retinoids; neogastropod; gastropod; imposex; tributyltin; bisphenol A
MeSH headings : Amino Acid Sequence; Androgens / physiology; Animals; Estradiol / metabolism; Estrogens / physiology; Female; Male; Molecular Sequence Data; Phylogeny; RNA, Messenger / metabolism; Receptors, Androgen / metabolism; Receptors, Estrogen / analysis; Receptors, Estrogen / metabolism; Reproduction / physiology; Sexual Maturation / physiology; Snails / physiology; Testosterone / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018
2007 journal article
Prenatal testosterone exposure permanently masculinizes anogenital distance, nipple development, and reproductive tract morphology in female Sprague-Dawley rats
TOXICOLOGICAL SCIENCES, 96(2), 335–345.
co-author countries:
United States of America 🇺🇸
author keywords: AGD; areola; masculinization; reproductive development; fetal androgen; intrauterine position
MeSH headings : Abnormalities, Drug-Induced / etiology; Abnormalities, Drug-Induced / pathology; Anal Canal / abnormalities; Anal Canal / drug effects; Animals; Animals, Newborn / abnormalities; Endocrine Disruptors / chemistry; Endocrine Disruptors / toxicity; Estrus / drug effects; Estrus / physiology; Female; Fetus / abnormalities; Fetus / drug effects; Genitalia, Female / abnormalities; Genitalia, Female / drug effects; Gestational Age; Male; Nipples / drug effects; Nipples / embryology; Nipples / growth & development; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Testosterone / chemistry; Testosterone / toxicity; Uterus / abnormalities; Uterus / drug effects; Vagina / abnormalities; Vagina / drug effects; Weight Loss / drug effects
Source: Web Of Science
Added: August 6, 2018
2005 journal article
The anogenital distance index of mice (Mus musculus domesticus): An analysis
Contemporary Topics in Laboratory Animal Science, 44(4), 46–48.
Source: NC State University Libraries
Added: August 6, 2018
2004 journal article
A mixture of the "antiandrogens" linuron and butyl benzyl phthalate alters sexual differentiation of the male rat in a cumulative fashion
BIOLOGY OF REPRODUCTION, 71(6), 1852–1861.
co-author countries:
United States of America 🇺🇸
author keywords: androgen receptor; male reproductive tract; male sexual function; testosterone; toxicology
MeSH headings : Anal Canal / anatomy & histology; Androgen Antagonists / administration & dosage; Androgen Antagonists / pharmacology; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Female; Fetus / metabolism; Genitalia, Male / anatomy & histology; Genitalia, Male / embryology; Linuron / administration & dosage; Linuron / pharmacology; Male; Osmolar Concentration; Phthalic Acids / administration & dosage; Phthalic Acids / pharmacology; Pregnancy; Prenatal Exposure Delayed Effects; Progesterone / metabolism; Rats; Rats, Sprague-Dawley; Sex Differentiation / drug effects; Testis / metabolism; Testosterone / metabolism
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Effects of prenatal testosterone propionate on the sexual development of male and female rats: A dose-response study
TOXICOLOGICAL SCIENCES, 65(1), 71–86.
author keywords: testosterone propionate; androgens; masculinization; prenatal exposure; sexual differentiation; anogenital distance; agenesis of the lower vagina; Sprague-Dawley rats
MeSH headings : Abnormalities, Drug-Induced / etiology; Anal Canal / abnormalities; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Female; Genitalia, Female / abnormalities; Genitalia, Male / abnormalities; Gonadal Steroid Hormones / administration & dosage; Gonadal Steroid Hormones / physiology; Gonadal Steroid Hormones / toxicity; Male; Maternal Exposure / adverse effects; Nipples / abnormalities; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Testosterone / administration & dosage; Testosterone / physiology; Testosterone / toxicity; Toxicity Tests; Vagina / abnormalities
Sources: Web Of Science, ORCID
Added: August 6, 2018
2001 patent
Altering sex ratio of offspring in mammals
Washington, DC: U.S. Patent and Trademark Office.
Source: NC State University Libraries
Added: August 6, 2018
2000 journal article
Cellular and molecular mechanisms of action of linuron: An antiandrogenic herbicide that produces reproductive malformations in male rats
TOXICOLOGICAL SCIENCES, 56(2), 389–399.
co-author countries:
United States of America 🇺🇸
author keywords: androgen binding; flutamide; linuron; reproductive malformations; androgen receptor (AR) antagonists
MeSH headings : Abnormalities, Drug-Induced; Androgen Antagonists / toxicity; Animals; COS Cells; Dibutyl Phthalate / toxicity; Dihydrotestosterone / pharmacology; Dose-Response Relationship, Drug; Female; Genitalia, Male / abnormalities; Genitalia, Male / drug effects; Genitalia, Male / pathology; Herbicides / toxicity; Linuron / toxicity; Male; Pregnancy; Rats; Rats, Sprague-Dawley; Transcriptional Activation / drug effects
Source: Web Of Science
Added: August 6, 2018
1999 journal article
Environmental antiandrogens: The malformation pattern varies with the mechanism of antiandrogenic action.
Biology of Reproduction, 60(1999), 201.
Source: NC State University Libraries
Added: August 6, 2018
1999 journal article
Environmental toxins - Exposure to bisphenol A advances puberty
NATURE, 401(6755), 763–764.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Benzhydryl Compounds; Body Weight / drug effects; Estrogens, Non-Steroidal / pharmacology; Female; Fetus / drug effects; Humans; Male; Mice; Models, Biological; Phenols / pharmacology; Pregnancy; Prenatal Exposure Delayed Effects; Sexual Maturation / drug effects
Source: Web Of Science
Added: August 6, 2018
