Works (9)
Updated: August 3rd, 2023 21:17
2013 journal article
Effects of quinapril on angiotensin converting enzyme and plasma renin activity as well as pharmacokinetic parameters of quinapril and its active metabolite, quinaprilat, after intravenous and oral administration to mature horses
EQUINE VETERINARY JOURNAL, 46(6), 729–733.
author keywords: horse; angiotensin converting enzyme; renin; mitral insufficiency
MeSH headings : Administration, Intravenous; Administration, Oral; Angiotensin-Converting Enzyme Inhibitors / blood; Angiotensin-Converting Enzyme Inhibitors / metabolism; Angiotensin-Converting Enzyme Inhibitors / pharmacokinetics; Angiotensin-Converting Enzyme Inhibitors / pharmacology; Animals; Area Under Curve; Gene Expression Regulation, Enzymologic; Half-Life; Horses / blood; Horses / metabolism; Peptidyl-Dipeptidase A / blood; Peptidyl-Dipeptidase A / genetics; Peptidyl-Dipeptidase A / metabolism; Quinapril; Renin / blood; Tetrahydroisoquinolines / blood; Tetrahydroisoquinolines / metabolism; Tetrahydroisoquinolines / pharmacokinetics; Tetrahydroisoquinolines / pharmacology
TL;DR:
Results suggest that, despite low plasma concentrations, quinapril has sufficient oral absorption to produce inhibition of ACE in healthy horses and provides a potential treatment alternative for horses with cardiovascular and renal disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Aqueous humor and plasma concentrations of a compounded 0.2% solution of terbinafine following topical ocular administration to normal equine eyes
Veterinary Ophthalmology, 14(1), 41–47.
author keywords: aqueous humor; equine; keratomycosis; terbinafine
MeSH headings : Absorption; Animals; Antifungal Agents / administration & dosage; Antifungal Agents / analysis; Antifungal Agents / blood; Antifungal Agents / pharmacokinetics; Aqueous Humor / chemistry; Chromatography, High Pressure Liquid / veterinary; Cornea / metabolism; Female; Horses / metabolism; Male; Naphthalenes / administration & dosage; Naphthalenes / analysis; Naphthalenes / blood; Naphthalenes / pharmacokinetics; Ophthalmic Solutions; Terbinafine
TL;DR:
Topical ocular administration of compounded 0.2% terbinafine solution does not result in detectable AH or plasma levels following administration to normal equine eyes, suggesting its use for deep corneal or intraocular fungal infections in equine ophthalmology may be limited.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2011 journal article
Intravenous and sublingual buprenorphine in horses: pharmacokinetics and influence of sampling site
VETERINARY ANAESTHESIA AND ANALGESIA, 38(4), 374–384.
author keywords: analgesia; buprenorphine; equine; opioids; pharmacokinetics; sampling site
MeSH headings : Administration, Sublingual; Analgesics, Opioid / administration & dosage; Analgesics, Opioid / blood; Analgesics, Opioid / pharmacokinetics; Animals; Biological Availability; Blood Chemical Analysis / methods; Blood Chemical Analysis / veterinary; Buprenorphine / administration & dosage; Buprenorphine / analogs & derivatives; Buprenorphine / blood; Buprenorphine / pharmacokinetics; Cross-Over Studies; Horses / metabolism; Injections, Intravenous / veterinary; Jugular Veins; Male; Prospective Studies
TL;DR:
Buprenorphine has a long plasma half-life and results in plasma concentrations that are consistent with analgesia in other species for up to 4 hours following IV administration of this dose in horses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Pharmacokinetics of intravenous and intramuscular buprenorphine in the horse
Journal of Veterinary Pharmacology and Therapeutics, 35(1), 52–58.
MeSH headings : Analgesics, Opioid / administration & dosage; Analgesics, Opioid / blood; Analgesics, Opioid / pharmacokinetics; Animals; Area Under Curve; Buprenorphine / administration & dosage; Buprenorphine / blood; Buprenorphine / pharmacokinetics; Cross-Over Studies; Female; Half-Life; Horses / blood; Horses / metabolism; Injections, Intramuscular; Injections, Intravenous; Male
TL;DR:
Buprenorphine has a moderate T(1/2) in the horse and was detected at concentrations expected to be therapeutic in other species after i.v. and i.m. administration of 0.005 mg/kg.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Aqueous humor and plasma concentrations of ciprofloxacin and moxifloxacin following topical ocular administration in ophthalmologically normal horses
American Journal of Veterinary Research, 71(5), 564–569.
MeSH headings : Administration, Oral; Administration, Topical; Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / blood; Anti-Infective Agents / metabolism; Aqueous Humor / metabolism; Aza Compounds / administration & dosage; Aza Compounds / blood; Aza Compounds / metabolism; Ciprofloxacin / administration & dosage; Ciprofloxacin / blood; Ciprofloxacin / metabolism; Female; Fluoroquinolones; Horses / blood; Horses / metabolism; Male; Moxifloxacin; Orchiectomy / veterinary; Quinolines / administration & dosage; Quinolines / blood; Quinolines / metabolism
TL;DR:
Moxifloxacin was better able to penetrate healthy equine corneas and reach measurable AH concentrations than was ciprofloxacIn, suggesting moxif loxac in might be of greater value in the treatment of deep corneal or intraocular bacterial infections caused by susceptible organisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2007 journal article
Cardiovascular effects of acute pulmonary obstruction in horses with recurrent airway obstruction
JOURNAL OF VETERINARY INTERNAL MEDICINE, 21(2), 302–307.
author keywords: cardiac; echocardiogram; equine; heaves
open access via onlinelibrary.wiley.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2004 journal article
Moxifloxacin pharmacokinetics in horses and disposition into phagocytes after oral dosing
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 27(1), 57–60.
MeSH headings : Administration, Oral; Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / blood; Anti-Infective Agents / pharmacokinetics; Area Under Curve; Aza Compounds / administration & dosage; Aza Compounds / blood; Aza Compounds / pharmacokinetics; Female; Fluoroquinolones; Horses / metabolism; Moxifloxacin; Phagocytes / metabolism; Quinolines / administration & dosage; Quinolines / blood; Quinolines / pharmacokinetics
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2004 journal article
Pharmacokinetics and pharmacodynamics of furosemide after oral administration to horses
JOURNAL OF VETERINARY INTERNAL MEDICINE, 18(5), 739–743.
author keywords: equine; frusemide; loop diuretic; oral bioavailability
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2003 journal article
Furosemide continuous rate infusion in the horse: Evaluation of enhanced efficacy and reduced side effects
JOURNAL OF VETERINARY INTERNAL MEDICINE, 17(6), 887–895.
author keywords: electrolyte; equine; fluid balance; frusemide; lasix; loop diuretic
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
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