Works (2)

Updated: July 5th, 2023 15:33

2019 journal article

Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury


By: T. Su n, K. Huang n, H. Ma*, H. Liang n, P. Dinh n, J. Chen n, D. Shen n, T. Allen n ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
author keywords: biomimetics; drug delivery; ischemic injury; platelets; stromal cell secretome
Sources: Web Of Science, ORCID
Added: February 4, 2019

2018 journal article

Heat shock promotes inclusion body formation of mutant huntingtin (mHtt) and alleviates mHtt-induced transcription factor dysfunction


By: J. Chen*, M. Parekh, H. Seliman, D. Bakshinskaya, W. Dai, K. Kwan, K. Chen*, A. Liu

co-author countries: United States of America 🇺🇸
author keywords: Huntington's disease; aggregation; heat shock protein (HSP); chaperone; heat shock factor protein 1 (HSF1); neurodegeneration; HSP chaperones; heat shock; inclusion bodies; polyQ-mHtt protein; transcription factor sequestration; CREB
MeSH headings : Animals; Cell Nucleus / drug effects; Cell Nucleus / metabolism; Cell Nucleus / pathology; Corpus Striatum / metabolism; Corpus Striatum / pathology; Cyclic AMP Response Element-Binding Protein / genetics; Cyclic AMP Response Element-Binding Protein / metabolism; Cytosol / drug effects; Cytosol / metabolism; Cytosol / pathology; Ecdysterone / analogs & derivatives; Ecdysterone / pharmacology; Embryo, Mammalian; Gene Expression Regulation; HSC70 Heat-Shock Proteins / genetics; HSC70 Heat-Shock Proteins / metabolism; HSP70 Heat-Shock Proteins / genetics; HSP70 Heat-Shock Proteins / metabolism; Heat Shock Transcription Factors / genetics; Heat Shock Transcription Factors / metabolism; Heat-Shock Response; Huntingtin Protein / genetics; Huntingtin Protein / metabolism; Huntington Disease / chemically induced; Huntington Disease / genetics; Huntington Disease / metabolism; Huntington Disease / pathology; Inclusion Bodies / chemistry; Inclusion Bodies / drug effects; Inclusion Bodies / metabolism; Models, Biological; Mutation; NF-kappa B / genetics; NF-kappa B / metabolism; Neurons / drug effects; Neurons / metabolism; Neurons / pathology; PC12 Cells; Primary Cell Culture; Rats; Sorbitol / pharmacology
Source: Web Of Science
Added: October 22, 2018