Works Published in 2004
Displaying works 21 - 40 of 139 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2004 journal article
Identification of Transthyretin Variants by Sequential Proteomic and Genomic Analysis
Clinical Chemistry, 50(9), 1544–1552.
MeSH headings : Amyloidosis, Familial / diagnosis; Amyloidosis, Familial / genetics; DNA / chemistry; DNA / genetics; Gas Chromatography-Mass Spectrometry / instrumentation; Gas Chromatography-Mass Spectrometry / methods; Genomics / methods; Genotype; Humans; Polymerase Chain Reaction; Polymorphism, Genetic; Prealbumin / chemistry; Prealbumin / genetics; Proteomics / methods; Sequence Analysis, DNA; Spectrometry, Mass, Electrospray Ionization / instrumentation; Spectrometry, Mass, Electrospray Ionization / methods
TL;DR:
This method correctly identified all previously known variants and also identified a novel variant, Val94Ala, which allows screening for the familial forms of amyloidosis in a broad patient population in a timely fashion.
(via Semantic Scholar)
clinchem.aaccjnls.org (publisher PDF)
Sources: Crossref, NC State University Libraries
Added: February 27, 2021
2004 journal article
Discovery of Ovarian Cancer Biomarkers in Serum Using NanoLC Electrospray Ionization TOF and FT-ICR Mass Spectrometry
Disease Markers, 19(4-5), 239–249.
MeSH headings : Amino Acid Sequence; Biomarkers, Tumor / blood; Chromatography; Female; Humans; Middle Aged; Molecular Sequence Data; Nanotechnology; Neoplasm Staging; Ovarian Neoplasms / blood; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization
TL;DR:
A set of protocols for the isolation and identification of serum biomarkers for ovarian cancer that exist in the low molecular weight serum fraction is delineated and one of these contains the sequence of fibrinopeptide-A known to be elevated in many types of cancer including ovarian cancer.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 12, 2021
2004 journal article
Identification and Characterization of Novel, Naturally Processed Measles Virus Class II HLA-DRB1 Peptides
Journal of Virology, 78(1), 42–51.
MeSH headings : Alleles; Cytokines / biosynthesis; Cytokines / genetics; HLA-DR Antigens / chemistry; HLA-DR Antigens / metabolism; HLA-DRB1 Chains; Humans; Interferon-gamma / biosynthesis; Interferon-gamma / genetics; Interleukin-4 / biosynthesis; Interleukin-4 / genetics; Measles / immunology; Measles / prevention & control; Measles virus / immunology; Measles virus / metabolism; Measles-Mumps-Rubella Vaccine / administration & dosage; Nucleocapsid Proteins; Nucleoproteins / chemistry; Nucleoproteins / immunology; Nucleoproteins / metabolism; Peptides / chemical synthesis; Peptides / chemistry; Peptides / immunology; Peptides / metabolism; T-Lymphocytes / immunology; Viral Proteins / chemistry; Viral Proteins / immunology; Viral Proteins / metabolism
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 12, 2021
2004 chapter
Sex Pheromones of Cockroaches
In R. T. Cardé & J. Millar (Eds.), Advances in Insect Chemical Ecology (pp. 179–247). New York: Cambridge University Press.
Ed(s): R. Cardé & J. Millar
Source: NC State University Libraries
Added: January 23, 2021
2004 journal article
Factor analysis of pesticide use patterns among pesticide applicators in the Agricultural Health Study
Journal of Exposure Science & Environmental Epidemiology, 15(3), 225–233.
author keywords: pesticides; farmers; custom applicators; factor analysis; herbicides; insecticides; fungicides; fumigants; Iowa; North Carolina
MeSH headings : Adult; Age Factors; Agriculture; Cohort Studies; Factor Analysis, Statistical; Female; Humans; Iowa; Life Style; Male; Middle Aged; Occupational Exposure; Pesticides / analysis; Risk Assessment; Spouses
TL;DR:
Heterogeneity in exposure patterns to pesticides did not correlate with lifestyle characteristics such as race, smoking status or education, which may be used to guide etiologic studies of health effects of farmers and other groups exposed to pesticides.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 21, 2021
2004 journal article
Roles of uptake, biotransformation, and target site sensitivity in determining the differential toxicity of chlorpyrifos to second to fourth instar Chironomous riparius (Meigen)
Aquatic Toxicology, 66(2), 149–157.
author keywords: chlorpyrifos; acetylcholinesterase; biotransformation; life stages; Chironomous
MeSH headings : Acetylcholinesterase / metabolism; Animals; Chironomidae / metabolism; Chlorpyrifos / metabolism; Chlorpyrifos / pharmacokinetics; Chlorpyrifos / toxicity; Dose-Response Relationship, Drug; Down-Regulation / drug effects; Larva / metabolism; Toxicity Tests
TL;DR:
It appeared that chlorpyrifos sensitivity differences among second to fourth instar C. riparius were largely determined by differences in uptake rates, which could potentially offset the apparent increased sensitivity to the oxon.
(via Semantic Scholar)
Source: Crossref
Added: January 21, 2021
2004 journal article
Estrogen receptor expression in a human primitive neuroectodermal tumor cell line from the cerebral cortex: estrogen stimulates rapid ERK1/2 activation and receptor-dependent cell migration
Biochemical and Biophysical Research Communications, 319(3), 753–758.
Contributors: M. Kirby*, A. Zsarnovszky* & S. Belcher*
author keywords: ER alpha; ER beta; ERK1/2; estrogen; estrogen receptor; growth; hormone responsive; MAPK; migration; non-genomic; PNET; signal transduction
MeSH headings : Animals; Brain Neoplasms / metabolism; Cell Line, Tumor; Cell Movement / physiology; Cerebral Cortex / metabolism; Cerebral Cortex / pathology; Enzyme Activation; Estrogens / metabolism; Humans; MAP Kinase Signaling System / physiology; Mitogen-Activated Protein Kinase 1 / metabolism; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases / metabolism; Neuroectodermal Tumors, Primitive / metabolism; Receptors, Estrogen / metabolism; Transcriptional Activation
TL;DR:
Results of immunoblot studies using ER-specific antiserum indicate that both ERalpha and ERbeta are expressed in PFSK1 cells, suggesting that rapid actions of E(2) and ER-mediated processes might contribute to the metastatic phenotype of some PNETs.
(via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: January 21, 2021
2004 journal article
Detection of Purkinje cell loss following drug exposures to developing rat pups using reverse transcriptase-polymerase chain reaction (RT-PCR) analysis for calbindin-D28k mRNA expression
Toxicology Letters, 150(3), 325–334.
Contributors: Y. Ge *, S. Belcher* , D. Pierce* & K. Light*
MeSH headings : Administration, Oral; Animals; Animals, Newborn; Calbindin 1; Calbindins; Cell Count; Dose-Response Relationship, Drug; Ethanol / toxicity; Female; Male; Pregnancy; Prenatal Exposure Delayed Effects; Purkinje Cells / cytology; Purkinje Cells / drug effects; Purkinje Cells / metabolism; RNA, Messenger / biosynthesis; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; S100 Calcium Binding Protein G / biosynthesis; Valproic Acid / toxicity
TL;DR:
Analysis of mRNA expression specific to calbindin-D28k by comparison to matched controls provides a reliable means of determining whether cell loss has occurred, regardless of whether the cell loss was induced by prenatal valproic acid or postnatal ethanol exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, ORCID, NC State University Libraries
Added: January 21, 2021
2004 journal article
Analytical Performance of a Venturi Device Integrated into an Electrospray Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometer for Analysis of Nucleic Acids
Analytical Chemistry, 76(14), 4118–4122.
MeSH headings : Cyclotrons; Fourier Analysis; Mass Spectrometry / instrumentation; Mass Spectrometry / methods; Oligonucleotides / analysis; Spectrometry, Mass, Electrospray Ionization / methods
TL;DR:
A voltage-assisted venturi device modeled after an industrial air amplifier was used to improve the ion transmission efficiency of a 16.2 kDa oligonucleotide and a 53-mer PCR product in the high-pressure region between an electrospray ionization emitter and the sampling orifices of two Fourier transform ion cyclotron resonance mass spectrometers (FT-ICR-MS).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 18, 2021
2004 journal article
Utility of accurate monoisotopic mass measurements to confidently identify lambda exonuclease generated single-stranded amplicons containing 7-deaza analogs by electrospray ionization FT-ICR mass spectrometry
International Journal of Mass Spectrometry, 234(1-3), 79–87.
Sources: Crossref, NC State University Libraries
Added: January 18, 2021
2004 journal article
Involvement of ASK1 in Ca 2+ ‐induced p38 MAP kinase activation
EMBO Reports, 5(2), 161–166.
MeSH headings : Animals; Calcium / metabolism; Calcium / pharmacology; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases / metabolism; Cells, Cultured; Fibroblasts / drug effects; Fibroblasts / metabolism; Glutathione Transferase / analysis; MAP Kinase Kinase Kinase 5 / metabolism; MAP Kinase Kinase Kinase 5 / physiology; MAP Kinase Signaling System / physiology; Marine Toxins / pharmacology; Mice; Mice, Inbred C57BL; Oxocins / pharmacology; Phosphorylation; Potassium Channels, Calcium-Activated / metabolism; RNA, Small Interfering / pharmacology; Synaptosomes / drug effects; Synaptosomes / metabolism; p38 Mitogen-Activated Protein Kinases / metabolism
TL;DR:
It is shown that Ca2+ signalling regulates the ASK1–p38 MAP kinase cascade, which is a critical intermediate of Ca2- signalling between CaMKII and p38 MAP Kinase.
(via Semantic Scholar)
Source: Crossref
Added: January 5, 2021
2004 journal article
Pendimethalin exposure and cancer risk among pesticide applicators: a report from the U.S.-based agricultural health study
Annals of Epidemiology, 14(8), 608.
TL;DR:
The findings suggest a possible association between pendimethalin exposure and incidence of rectum and lung cancers among pesticide applicators in the U.S. Agricultural Health Study.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 10, 2020
2004 journal article
Energy intake and physical activity during short-term smoking cessation in postmenopausal women
Addictive Behaviors, 29(5), 947–951.
author keywords: energy intake; smoking cessation; postmenopausal women
MeSH headings : Adult; Aged; Analysis of Variance; Dietary Carbohydrates / administration & dosage; Energy Intake / physiology; Exercise / physiology; Female; Hormone Replacement Therapy / methods; Humans; Middle Aged; Postmenopause / metabolism; Postmenopause / psychology; Smoking / metabolism; Smoking Cessation; Weight Gain / physiology
TL;DR:
These are the first published findings on caloric intake and weight gain during smoking abstinence in postmenopausal women-an understudied population in the smoking cessation literature.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 8, 2020
2004 journal article
Characteristics of cigarette smokers seeking treatment for cessation versus reduction
Addictive Behaviors, 29(2), 357–364.
author keywords: cigarette smoking; smoking cessation; smoking reduction; research subjects
MeSH headings : Adult; Alcohol Drinking / psychology; Diagnosis, Dual (Psychiatry); Female; Health Status; Humans; Logistic Models; Male; Middle Aged; Motivation; Patient Acceptance of Health Care / psychology; Smoking / psychology; Smoking Cessation / psychology; Substance-Related Disorders / psychology
TL;DR:
The results indicate that cigarette smokers seeking treatment for smoking reduction but not cessation may be more dependent smokers who experience more medical disorders.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 8, 2020
2004 journal article
Characterization of termite lipophorin and its involvement in hydrocarbon transport
Journal of Insect Physiology, 50(7), 609–620.
author keywords: Reticulitermes flavipes; ELISA; hydrocarbon; lipophorin termite
MeSH headings : Animals; Antibodies / immunology; Biological Transport; Carrier Proteins / immunology; Carrier Proteins / isolation & purification; Carrier Proteins / metabolism; Enzyme-Linked Immunosorbent Assay; Hemolymph / chemistry; Hydrocarbons / metabolism; Insect Proteins / immunology; Insect Proteins / isolation & purification; Insect Proteins / metabolism; Isoptera / chemistry; Isoptera / immunology; Isoptera / physiology; Lipoproteins / immunology; Lipoproteins / isolation & purification; Lipoproteins / metabolism; Lipoproteins, HDL / immunology; Lipoproteins, HDL / isolation & purification; Lipoproteins, HDL / metabolism; Sensitivity and Specificity; Species Specificity
TL;DR:
Involvement of lipophorin in hydrocarbon transport was shown by injecting HDLp antisersum into Zootermopsis nevadensis and then monitoring the de novo biosynthesis of hydrocarbons and their transport to the cuticular surface; the antiserum significantly disrupted hydrocarbon Transport.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: September 6, 2020
2004 journal article
Phthalate exposure and pulmonary function.
Environmental Health Perspectives, 112(5), 571–574.
author keywords: monobutyl phthalate; pulmonary function; urine samples
MeSH headings : Adult; Biomarkers; Environmental Exposure; Female; Humans; Linear Models; Lung / drug effects; Lung / physiology; Male; Middle Aged; Nutrition Surveys; Phthalic Acids / toxicity; Phthalic Acids / urine; Respiratory Function Tests; Sex Factors
TL;DR:
It is suggested that MBP and MEP, but not MEHP, may influence pulmonary function among adult males, and the metabolite of the plasticizer commonly used in medical tubing was not adversely associated with any of the pulmonary function parameters evaluated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: September 3, 2020
2004 journal article
Cancer risk and parental pesticide application in children of Agricultural Health Study participants.
Environmental Health Perspectives, 112(5), 631–635.
author keywords: agricultural workers; cancer; children; occupational exposure; pesticides
MeSH headings : Adolescent; Adult; Agriculture; Child; Child, Preschool; Female; Humans; Incidence; Infant; Iowa; Lymphoma / chemically induced; Lymphoma / epidemiology; Male; Maternal Exposure / adverse effects; Neoplasms / chemically induced; Neoplasms / epidemiology; Paternal Exposure / adverse effects; Pesticides / toxicity; Prospective Studies; Retrospective Studies; Risk
TL;DR:
Analysis of childhood cancer risk and associations with parental pesticide application in Iowa suggests that farm exposures including pesticides may play a role in the etiology of childhood lymphoma.
(via Semantic Scholar)
Source: Crossref
Added: September 3, 2020
2004 journal article
Characterization of Human UDP-glucose Dehydrogenase
Journal of Biological Chemistry, 279(22), 23590–23596.
MeSH headings : Binding Sites; Catalytic Domain / genetics; Cysteine; Humans; Lysine; Oxidation-Reduction; Protein Conformation; Streptococcus pyogenes; Structure-Activity Relationship; Uridine Diphosphate Glucose Dehydrogenase / chemistry; Uridine Diphosphate Glucose Dehydrogenase / genetics; Uridine Diphosphate Glucose Dehydrogenase / metabolism
TL;DR:
Cloned, expressed, and affinity-purified the human UGDH and determined its steady state kinetic parameters, which are consistent with the postulated role of Cys-276 as a catalytic residue and supports its position in the reaction mechanism for the human enzyme.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2004 journal article
Of mice and missing data: what we know (and need to learn) about male sexual behavior
Physiology & Behavior, 83(2), 217–232.
Source: Crossref
Added: August 28, 2020
2004 journal article
Background matters: the effects of estrogen receptor α gene disruption on male sexual behavior are modified by background strain
Hormones and Behavior, 46(4), 482–490.
author keywords: sexual behavior; estrogen receptor; inbred strains; knockout mice; testosterone; aggression; lordosis; olfaction; DBA; BALB/c; C57BL/6J
MeSH headings : Analysis of Variance; Animals; Copulation / physiology; Ejaculation / physiology; Estrogen Receptor alpha / genetics; Estrogen Receptor alpha / physiology; Female; Fertility / genetics; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains / genetics; Mice, Inbred Strains / physiology; Mice, Knockout / genetics; Mice, Knockout / physiology; Sex Factors; Sexual Behavior, Animal / physiology; Species Specificity; Testosterone / physiology
TL;DR:
The data suggest that genetic background has dramatic effects on male sexual behavior and its dependence on the ERα gene.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
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