Abdulkerim Eroglu

Also known as: KERIM EROGLU

https://orcid.org/0000-0001-5350-450X

carotenoids, systems biology, proteomics, metagenomics, synthetic biology, gut microbiome

Works (18)

2022 journal article

Carotenoids in orange carrots mitigate non-alcoholic fatty liver disease progression

FRONTIERS IN NUTRITION, 9.

By: E. Balbuena, J. Cheng & A. Eroglu

author keywords: phytochemicals; nutrition; beta-oxidation; nuclear receptors; lipid metabolism
Sources: Web Of Science, ORCID
Added: October 24, 2022

2021 journal article

In Situ Biomanufacturing of Small Molecules in the Mammalian Gut by Probiotic Saccharomyces boulardii

ACS SYNTHETIC BIOLOGY, 10(5), 1039–1052.

author keywords: Saccharomyces boulardii; probiotic engineering; metabolic engineering; colonization profile; in situ production; beta-carotene
Sources: Web Of Science, ORCID
Added: May 6, 2021

2021 review

The Promising Effects of Astaxanthin on Lung Diseases

[Review of ]. ADVANCES IN NUTRITION, 12(3), 850–864.

By: J. Cheng & A. Eroglu

author keywords: astaxanthin; lung diseases; oxidative stress; molecular mechanism; lung cancer
Sources: Web Of Science, ORCID
Added: January 10, 2021

2021 journal article

The Role of beta-Carotene in Colonic Inflammation and Intestinal Barrier Integrity

FRONTIERS IN NUTRITION, 8.

By: J. Cheng, E. Balbuena, B. Miller n & A. Eroglu

author keywords: beta-carotene; colonic inflammation; colonic epithelial cells; tight junctions; vitamin A
Sources: Web Of Science, ORCID
Added: November 23, 2021

2020 journal article

Lycopene Protects against Smoking-Induced Lung Cancer by Inducing Base Excision Repair

Antioxidants.

By: J. Cheng n, B. Miller n, E. Balbuena n & A. Eroğlu

author keywords: lycopene; beta-carotene; lung cancer; base excision repair; gap junction communication; all-trans retinoic acid; oxidative stress
Source: ORCID
Added: July 26, 2020

2020 article

Nutrient modulation of DNA repair in lung cancer

Eroglu, A., & Balbuena, E. (2020, April). FASEB JOURNAL, Vol. 34.

By: A. Eroglu & E. Balbuena

Sources: Web Of Science, ORCID
Added: October 12, 2020

2020 article

The Colors of Health: Chemistry, Bioactivity, and Market Demand for Colorful Foods and Natural Food Sources of Colorants

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 11, Vol. 11, pp. 145–182.

By: E. Mejia*, Q. Zhang*, K. Penta n, A. Eroglu & M. Lila

author keywords: anthocyanins; betalains; bioactivity; carotenoids; natural colors; phycocyanins
Sources: Web Of Science, ORCID
Added: April 27, 2020

2019 journal article

Investigation into the use of histone deacetylase inhibitor MS-275 as a topical agent for the prevention and treatment of cutaneous squamous cell carcinoma in an SKH-1 hairless mouse model.

PloS One.

Ed(s): T. Oberyszyn

Source: ORCID
Added: May 4, 2019

2018 journal article

A plasma proteome is associated with carotenoid status and dietary intake of food sources of carotenoids in Nepalese school aged children

Archives of Biochemistry and Biophysics, 646, 153–160.

By: A. Eroglu, K. Schulze, J. Yager, R. Cole, P. Christian, B. Nonyane, S. Lee, L. Wu ...

Source: NC State University Libraries
Added: February 8, 2019

2018 journal article

Plasma proteins associated with circulating carotenoids in Nepalese school-aged children.

Archives of Biochemistry and Biophysics.

By: A. Eroglu, K. Schulze*, J. Yager*, R. Cole*, P. Christian*, B. Nonyane*, S. Lee*, L. Wu* ...

author keywords: Proteomics; Plasma proteins; beta-cryptoxanthin; Antioxidants; Carotenoids; Nepal
Source: ORCID
Added: May 4, 2019

2018 journal article

Plasma proteome correlates of lipid and lipoprotein: biomarkers of metabolic diversity and inflammation in children of rural Nepal

Journal of Lipid Research, 60(1), 149–160.

By: S. Lee*, K. Schulze*, C. Stewart*, R. Cole*, L. Wu*, A. Eroğlu, J. Yager*, J. Groopman* ...

author keywords: plasma proteomics; high density lipoprotein-cholesterol; low density lipoprotein-cholesterol; triglycerides
Sources: Web Of Science, ORCID
Added: February 8, 2019

2018 journal article

Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

Nature Communications, 9(1), 53.

By: J. Kalin*, M. Wu*, A. Gomez*, Y. Song*, J. Das*, D. Hayward*, N. Adejola*, M. Wu* ...

Sources: Web Of Science, ORCID
Added: February 8, 2019

2017 journal article

Synthesis of apo-13- and apo-15-lycopenoids, cleavage products of lycopene that are retinoic acid antagonists

Journal of Lipid Research, 58(5), 1021–1029.

By: S. Narayanasamy*, J. Sun*, R. Pavlovicz*, A. Eroglu, C. Rush*, B. Sunkel*, C. Li*, E. Harrison*, R. Curley*

Sources: NC State University Libraries, ORCID
Added: February 8, 2019

2016 journal article

Inhibition of RPE65 retinol isomerase activity by inhibitors of lipid metabolism

Journal of Biological Chemistry, 291, 4966–4973.

By: A. Eroglu, S. Gentleman*, E. Poliakov* & T. Redmond*

author keywords: enzyme inhibitor; liposome; retinal metabolism; retinoid; vision; RPE65; triacsin C; visual cycle; fatty acyl:CoA ligase
Sources: Web Of Science, ORCID
Added: February 8, 2019

2013 journal article

Carotenoid metabolism in mammals, including man; formation, occurrence, and function of apocarotenoids

Journal of Lipid Research, 54, 1719–1730.

By: A. Eroglu & E. Harrison*

author keywords: retinoids; vitamin A; beta-carotene; lycopene
Sources: Web Of Science, ORCID
Added: February 8, 2019

2012 journal article

Naturally-occurring eccentric cleavage products of provitamin A carotene b-carotene function as antagonists of retinoic acid receptors

Journal of Biological Chemistry, 287, 15886–158995.

By: A. Eroglu, D. Hruszkewycz*, C. Sena*, S. Narayanasamy*, K. Riedl*, R. Kopec*, S. Schwartz*, E. Harrison*, R. Curley*

Sources: Web Of Science, ORCID
Added: February 8, 2019

2012 journal article

The formation, occurrence and function of b-apocarotenoids: b-Carotene metabolites that may modulate nuclear receptor signaling

American Journal of Clinical Nutrition, 96, 1189–1192.

By: E. Harrison*, C. Sena*, A. Eroglu & M. Fleshman*

Sources: Web Of Science, ORCID
Added: February 8, 2019

2010 journal article

The eccentric cleavage product of b- carotene, b-apo-13-carotenone, functions as an antagonist of RXRa

Archives of Biochemistry and Biophysics, 504, 11–16.

By: A. Eroglu, D. Hruszkewycz*, R. Curley* & E. Harrison*

author keywords: beta-Apocarotenoids; Retinoids; Retinoid receptors; Carotenoids
Sources: Web Of Science, ORCID
Added: February 8, 2019

Employment

2018 - present

North Carolina State University Raleigh, NC, US
Assistant Professor Molecular and Structural Biochemistry

2016 - 2018

Johns Hopkins Bloomberg School of Public Health Baltimore, MD, US
Micronutrient Lab Manager International Health

2015 - 2016

Johns Hopkins School of Medicine Baltimore, MD, US
Research Scholar Pharmacology and Molecular Sciences

2012 - 2015

National Institutes of Health Bethesda, MD, US
Post-doc National Eye Institute

2005 - 2006

Nationwide Children's Hospital Columbus, OH, US
Research Assistant Center for Vaccines and Immunity

Education

2006 - 2012

The Ohio State University Columbus, Ohio, US
Ph.D. Biochemistry

2001 - 2005

Haliç Üniversitesi Istanbul, TR
B.Sc. Molecular Biology and Genetics